Gene: Agtr2 (angiotensin II receptor, type 2) Rattus norvegicus
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Symbol: Agtr2
Name: angiotensin II receptor, type 2
Description: Exhibits transcription factor binding activity; involved in several processes, including aldosterone secretion, animal organ development, and regulation of secretion; localizes to the perinuclear region of cytoplasm and plasma membrane; used to study artery disease (multiple), chronic kidney disease, congenital diaphragmatic hernia, glomerulonephritis (multiple), and meconium aspiration syndrome; biomarker of several diseases, including asthma, congestive heart failure, dilated cardiomyopathy, glomerulonephritis (multiple), and hypertension; orthologous to human AGTR2 (angiotensin II receptor type 2); PARTICIPATES IN angiotensin III signaling pathway via AT2 receptor; angiotensin II signaling pathway via AT2 receptor; G protein mediated signaling pathway via Galphai family; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 3',5'-cyclic GMP.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: angiotensin II type 2 receptor; angiotensin II type-2 receptor; Angiotensin receptor 2; AT2; AT2-R; AT2R; AT2R; type-2 angiotensin II receptor
Orthologs:
Homo sapiens (human) : AGTR2 (angiotensin II receptor type 2)  HGNC  Alliance
Mus musculus (house mouse) : Agtr2 (angiotensin II receptor, type 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Agtr2 (angiotensin II receptor type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AGTR2 (angiotensin II receptor type 2)
Canis lupus familiaris (dog) : AGTR2 (angiotensin II receptor type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agtr2 (angiotensin II receptor type 2)
Sus scrofa (pig) : AGTR2 (angiotensin II receptor type 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X119,389,480 - 119,393,845 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X119,534,483 - 119,538,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX111,375,374 - 111,376,465 (+)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

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Sequence

Nucleotide Sequences
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Strain Sequence Variants (Rnor 5.0)

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RGD Curation Notes
  
More on Agtr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2072
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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