Gene: Agtr2 (angiotensin II receptor, type 2) Rattus norvegicus
Symbol: Agtr2
Name: angiotensin II receptor, type 2
Description: Exhibits transcription factor binding activity; involved in several processes, including aldosterone secretion, animal organ development, and regulation of secretion; localizes to the perinuclear region of cytoplasm and plasma membrane; used to study artery disease (multiple), chronic kidney disease, congenital diaphragmatic hernia, glomerulonephritis (multiple), and meconium aspiration syndrome; biomarker of several diseases, including asthma, congestive heart failure, dilated cardiomyopathy, glomerulonephritis (multiple), and hypertension; orthologous to human AGTR2 (angiotensin II receptor type 2); PARTICIPATES IN angiotensin III signaling pathway via AT2 receptor; angiotensin II signaling pathway via AT2 receptor; G protein mediated signaling pathway via Galphai family; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 3',5'-cyclic GMP.
Type: protein-coding
Also known as: angiotensin II type 2 receptor; angiotensin II type-2 receptor; Angiotensin receptor 2; AT2; AT2-R; AT2R; AT2R; type-2 angiotensin II receptor
Homo sapiens (human) : AGTR2 (angiotensin II receptor type 2)  HGNC  Alliance
Mus musculus (house mouse) : Agtr2 (angiotensin II receptor, type 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Agtr2 (angiotensin II receptor type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AGTR2 (angiotensin II receptor type 2)
Canis lupus familiaris (dog) : AGTR2 (angiotensin II receptor type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agtr2 (angiotensin II receptor type 2)
Sus scrofa (pig) : AGTR2 (angiotensin II receptor type 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X119,389,480 - 119,393,845 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X119,534,483 - 119,538,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX111,375,374 - 111,376,465 (+)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Protein Structures

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Agtr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2072
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.