Gene: St6gal1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Rattus norvegicus
Analyze
Symbol:
St6gal1
Name:
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
Description:
Exhibits sialyltransferase activity. Involved in several processes, including negative regulation of macrophage apoptotic process; protein sialylation; and regulation of substrate adhesion-dependent cell spreading. Localizes to Golgi medial cisterna; Golgi trans cisterna; and endoplasmic reticulum. Used to study malignant glioma. Orthologous to human ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1); PARTICIPATES IN N-linked glycan biosynthetic pathway; O-linked glycan biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
alpha 2,6-ST 1; beta galactoside alpha 2,6 sialyltransferase 1; beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; sialyltransferase 1; Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase); Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase); Siat1; ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6Gal I; ST6GalI
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
St6gal1 (beta galactoside alpha 2,6 sialyltransferase 1) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
St6gal1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
St6gal1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
St6gal1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
St6gal1 (beta galactoside alpha 2,6 sialyltransferase 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Homo sapiens (human):
ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
st6gal1 (ST6 beta-galactosamide alpha-2,6-sialyltranferase 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|OrthoFinder|PhylomeDB|TreeFam)
Drosophila melanogaster (fruit fly):
SiaT
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 11 80,927,601 - 80,981,424 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 11 80,927,601 - 80,981,422 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 11 79,754,201 - 79,808,024 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 11 79,723,269 - 79,765,645 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 11 79,780,860 - 79,789,781 (-) NCBI Celera 11 76,402,694 - 76,445,042 (-) NCBI Celera Cytogenetic Map 11 q23 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
3MC syndrome 1 ISO RGD:1601776 8554872 ClinVar Annotator: match by term: 3MC syndrome 1 ClinVar PMID:28492532 3MC syndrome 1 ISO RGD:1601776 8554872 ClinVar Annotator: match by term: Michels syndrome ClinVar PMID:28492532 , PMID:29407414
Imported Annotations - CTD
allergic contact dermatitis ISO RGD:1601776 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16033404 type 2 diabetes mellitus ISO RGD:1601776 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21874001
1,2-dimethylhydrazine decreases expression ISO RGD:736316 6480464 1, 2-Dimethylhydrazine results in decreased expression of ST6GAL1 mRNA CTD PMID:22206623 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of ST6GAL1 mRNA CTD PMID:12655037 17beta-estradiol decreases expression ISO RGD:1601776 6480464 Estradiol results in decreased expression of ST6GAL1 mRNA CTD PMID:20106945 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:1601776 6480464 Dihydrotestosterone results in increased expression of ST6GAL1 mRNA CTD PMID:29581250 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:736316 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:736316 6480464 2 more ... CTD PMID:30294300 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:736316 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1601776 6480464 Tetrachlorodibenzodioxin results in decreased expression of ST6GAL1 mRNA CTD PMID:20106945 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:736316 6480464 Tetrachlorodibenzodioxin affects the expression of ST6GAL1 mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ST6GAL1 mRNA CTD PMID:19692669 , PMID:21724226 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ST6GAL1 mRNA CTD PMID:22298810 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of ST6GAL1 mRNA CTD PMID:21346803 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736316 6480464 Glucosamine results in increased expression of ST6GAL1 mRNA CTD PMID:17178593 2-butoxyethanol decreases expression ISO RGD:736316 6480464 n-butoxyethanol results in decreased expression of ST6GAL1 mRNA CTD PMID:19812364 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:19692669 , PMID:23196670 3,4-dichloroaniline increases expression EXP 6480464 3, 4-dichloroaniline results in increased expression of ST6GAL1 mRNA CTD PMID:24172598 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:736316 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of ST6GAL1 mRNA more ... CTD PMID:28031460 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of ST6GAL1 mRNA CTD PMID:19162173 4-hydroxyphenyl retinamide increases expression ISO RGD:736316 6480464 Fenretinide results in increased expression of ST6GAL1 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine multiple interactions ISO RGD:736316 6480464 Decitabine inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of ST6GAL1 mRNA] CTD PMID:28031460 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of ST6GAL1 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of ST6GAL1 mRNA CTD PMID:19483382 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of ST6GAL1 mRNA CTD PMID:31881176 aflatoxin B1 affects expression ISO RGD:1601776 6480464 Aflatoxin B1 affects the expression of ST6GAL1 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:1601776 6480464 Aflatoxin B1 results in decreased expression of ST6GAL1 mRNA CTD PMID:22100608 , PMID:27153756 aflatoxin B1 decreases expression ISO RGD:736316 6480464 Aflatoxin B1 results in decreased expression of ST6GAL1 mRNA CTD PMID:19770486 aldehydo-D-glucosamine increases expression ISO RGD:736316 6480464 Glucosamine results in increased expression of ST6GAL1 mRNA CTD PMID:17178593 all-trans-retinoic acid increases expression ISO RGD:736316 6480464 Tretinoin results in increased expression of ST6GAL1 mRNA CTD PMID:16604517 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of ST6GAL1 mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ST6GAL1 mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of ST6GAL1 mRNA CTD PMID:30779732 antirheumatic drug decreases expression ISO RGD:1601776 6480464 Antirheumatic Agents results in decreased expression of ST6GAL1 mRNA CTD PMID:25339124 atrazine decreases expression ISO RGD:1601776 6480464 Atrazine results in decreased expression of ST6GAL1 mRNA CTD PMID:22378314 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of ST6GAL1 mRNA CTD PMID:19483382 benzo[a]pyrene decreases expression ISO RGD:736316 6480464 Benzo(a)pyrene results in decreased expression of ST6GAL1 mRNA CTD PMID:19770486 benzo[a]pyrene affects methylation ISO RGD:1601776 6480464 Benzo(a)pyrene affects the methylation of ST6GAL1 intron CTD PMID:30157460 benzo[a]pyrene decreases expression ISO RGD:1601776 6480464 Benzo(a)pyrene results in decreased expression of ST6GAL1 mRNA CTD PMID:20064835 more ... beta-D-glucosamine increases expression ISO RGD:736316 6480464 Glucosamine results in increased expression of ST6GAL1 mRNA CTD PMID:17178593 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ST6GAL1 mRNA CTD PMID:25181051 , PMID:30903817 bisphenol A affects expression ISO RGD:1601776 6480464 bisphenol A affects the expression of ST6GAL1 mRNA CTD PMID:30903817 bisphenol A increases expression ISO RGD:1601776 6480464 bisphenol A results in increased expression of ST6GAL1 mRNA CTD PMID:27685785 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of ST6GAL1 mRNA CTD PMID:24136188 butanal decreases expression ISO RGD:1601776 6480464 butyraldehyde results in decreased expression of ST6GAL1 mRNA CTD PMID:26079696 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of ST6GAL1 mRNA CTD PMID:19167457 carbamazepine affects expression ISO RGD:1601776 6480464 Carbamazepine affects the expression of ST6GAL1 mRNA CTD PMID:25979313 carbon nanotube affects expression ISO RGD:736316 6480464 Nanotubes, Carbon affects the expression of ST6GAL1 mRNA CTD PMID:25620056 carbon nanotube decreases expression ISO RGD:736316 6480464 Nanotubes, Carbon analog results in decreased expression of ST6GAL1 mRNA CTD PMID:25620056 carmustine increases expression ISO RGD:1601776 6480464 Carmustine results in increased expression of ST6GAL1 mRNA CTD PMID:15980968 choline multiple interactions ISO RGD:736316 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ST6GAL1 gene CTD PMID:20938992 cisplatin decreases expression ISO RGD:1601776 6480464 Cisplatin results in decreased expression of ST6GAL1 mRNA CTD PMID:27594783 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of ST6GAL1 mRNA CTD PMID:19483382 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ST6GAL1 mRNA CTD PMID:17602206 copper(II) chloride decreases expression ISO RGD:1601776 6480464 cupric chloride results in decreased expression of ST6GAL1 mRNA CTD PMID:17211630 copper(II) sulfate decreases expression ISO RGD:1601776 6480464 Copper Sulfate results in decreased expression of ST6GAL1 mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO RGD:1601776 6480464 Cyclosporine results in decreased expression of ST6GAL1 mRNA CTD PMID:20106945 more ... desferrioxamine B multiple interactions ISO RGD:1601776 6480464 ST6GAL1 protein promotes the reaction [Deferoxamine results in increased expression of HIF1A protein] CTD PMID:29475939 dexamethasone multiple interactions ISO RGD:736316 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of ST6GAL1 mRNA more ... CTD PMID:28031460 diclofenac increases expression ISO RGD:736316 6480464 Diclofenac results in increased expression of ST6GAL1 mRNA CTD PMID:26934552 dioxygen multiple interactions ISO RGD:1601776 6480464 ST6GAL1 protein affects the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA] more ... CTD PMID:29475939 dioxygen affects response to substance ISO RGD:1601776 6480464 ST6GAL1 protein affects the susceptibility to Oxygen deficiency CTD PMID:29475939 diuron increases expression EXP 6480464 Diuron metabolite results in increased expression of ST6GAL1 mRNA CTD PMID:24172598 dorsomorphin multiple interactions ISO RGD:1601776 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ST6GAL1 mRNA CTD PMID:27188386 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of ST6GAL1 mRNA CTD PMID:29391264 ethyl methanesulfonate decreases expression ISO RGD:1601776 6480464 Ethyl Methanesulfonate results in decreased expression of ST6GAL1 mRNA CTD PMID:23649840 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of ST6GAL1 mRNA CTD PMID:18035473 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of ST6GAL1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:736316 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ST6GAL1 gene CTD PMID:20938992 folic acid decreases expression ISO RGD:736316 6480464 Folic Acid results in decreased expression of ST6GAL1 mRNA CTD PMID:25629700 fonofos decreases methylation ISO RGD:1601776 6480464 Fonofos results in decreased methylation of ST6GAL1 promoter CTD PMID:22847954 formaldehyde decreases expression ISO RGD:1601776 6480464 Formaldehyde results in decreased expression of ST6GAL1 mRNA CTD PMID:23649840 furan increases methylation EXP 6480464 furan results in increased methylation of ST6GAL1 gene CTD PMID:22079235 furan decreases expression EXP 6480464 furan results in decreased expression of ST6GAL1 mRNA CTD PMID:25539665 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of ST6GAL1 mRNA CTD PMID:22061828 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of ST6GAL1 mRNA CTD PMID:22061828 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of ST6GAL1 mRNA CTD PMID:19483382 L-methionine multiple interactions ISO RGD:736316 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ST6GAL1 gene CTD PMID:20938992 lithocholic acid decreases activity ISO RGD:1601776 6480464 Lithocholic Acid analog results in decreased activity of ST6GAL1 protein CTD PMID:21224350 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of ST6GAL1 mRNA CTD PMID:28801915 methyl methanesulfonate decreases expression ISO RGD:1601776 6480464 Methyl Methanesulfonate results in decreased expression of ST6GAL1 mRNA CTD PMID:23649840 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ST6GAL1 mRNA CTD PMID:17602206 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of ST6GAL1 mRNA CTD PMID:24136188 nickel dichloride increases expression ISO RGD:1601776 6480464 nickel chloride results in increased expression of ST6GAL1 mRNA CTD PMID:17312168 nicotinic acid increases expression EXP 6480464 Niacin results in increased expression of ST6GAL1 mRNA CTD PMID:20303128 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of ST6GAL1 mRNA CTD PMID:24136188 O-methyleugenol decreases expression ISO RGD:1601776 6480464 methyleugenol results in decreased expression of ST6GAL1 mRNA CTD PMID:32234424 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of ST6GAL1 mRNA CTD PMID:19483382 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ST6GAL1 mRNA CTD PMID:25729387 oxazepam increases expression ISO RGD:736316 6480464 Oxazepam results in increased expression of ST6GAL1 mRNA CTD PMID:12727805 p-toluidine decreases expression EXP 6480464 4-toluidine results in decreased expression of ST6GAL1 mRNA CTD PMID:27638505 paracetamol decreases expression ISO RGD:1601776 6480464 Acetaminophen results in decreased expression of ST6GAL1 mRNA CTD PMID:21420995 , PMID:29067470 parathion decreases methylation ISO RGD:1601776 6480464 Parathion results in decreased methylation of ST6GAL1 promoter CTD PMID:22847954 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of ST6GAL1 mRNA CTD PMID:19162173 phenylmercury acetate decreases expression ISO RGD:1601776 6480464 Phenylmercuric Acetate results in decreased expression of ST6GAL1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1601776 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ST6GAL1 mRNA CTD PMID:27188386 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of ST6GAL1 mRNA CTD PMID:19483382 pirinixic acid decreases expression ISO RGD:736316 6480464 pirinixic acid results in decreased expression of ST6GAL1 mRNA CTD PMID:12727805 , PMID:18445702 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of ST6GAL1 mRNA CTD PMID:19162173 quercetin decreases expression ISO RGD:1601776 6480464 Quercetin results in decreased expression of ST6GAL1 mRNA CTD PMID:21632981 SB 431542 multiple interactions ISO RGD:1601776 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ST6GAL1 mRNA CTD PMID:27188386 silicon dioxide decreases expression ISO RGD:1601776 6480464 Silicon Dioxide analog results in decreased expression of ST6GAL1 mRNA, Silicon Dioxide results in decreased expression of ST6GAL1 mRNA CTD PMID:25351596 , PMID:25895662 silicon dioxide increases expression ISO RGD:736316 6480464 Silicon Dioxide results in increased expression of ST6GAL1 mRNA CTD PMID:23221170 silicon dioxide decreases expression ISO RGD:736316 6480464 Silicon Dioxide results in decreased expression of ST6GAL1 mRNA CTD PMID:19073995 silver atom decreases expression ISO RGD:736316 6480464 Silver results in decreased expression of ST6GAL1 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:736316 6480464 Silver results in decreased expression of ST6GAL1 mRNA CTD PMID:27131904 sodium arsenite affects methylation ISO RGD:1601776 6480464 sodium arsenite affects the methylation of ST6GAL1 gene CTD PMID:28589171 sodium arsenite decreases expression ISO RGD:1601776 6480464 sodium arsenite results in decreased expression of ST6GAL1 mRNA CTD PMID:29301061 succimer multiple interactions ISO RGD:736316 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ST6GAL1 mRNA CTD PMID:21641980 tamoxifen decreases expression ISO RGD:736316 6480464 Tamoxifen results in decreased expression of ST6GAL1 mRNA CTD PMID:25123088 terbufos decreases methylation ISO RGD:1601776 6480464 terbufos results in decreased methylation of ST6GAL1 promoter CTD PMID:22847954 tetrachloromethane affects expression ISO RGD:736316 6480464 Carbon Tetrachloride affects the expression of ST6GAL1 mRNA CTD PMID:17484886 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of ST6GAL1 mRNA CTD PMID:16239168 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of ST6GAL1 mRNA CTD PMID:19483382 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of ST6GAL1 mRNA CTD PMID:25729387 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ST6GAL1 mRNA CTD PMID:25729387 triclosan decreases expression ISO RGD:1601776 6480464 Triclosan results in decreased expression of ST6GAL1 mRNA CTD PMID:30510588 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of ST6GAL1 mRNA CTD PMID:24136188 valproic acid decreases expression ISO RGD:1601776 6480464 Valproic Acid results in decreased expression of ST6GAL1 mRNA CTD PMID:29154799 , PMID:29501571 valproic acid affects methylation ISO RGD:1601776 6480464 Valproic Acid affects the methylation of ST6GAL1 gene CTD PMID:29501571 valproic acid affects expression ISO RGD:1601776 6480464 Valproic Acid affects the expression of ST6GAL1 mRNA CTD PMID:25979313 vancomycin decreases expression ISO RGD:736316 6480464 Vancomycin results in decreased expression of ST6GAL1 mRNA CTD PMID:18930951 vorinostat decreases expression ISO RGD:1601776 6480464 vorinostat results in decreased expression of ST6GAL1 mRNA CTD PMID:27188386 zoledronic acid increases expression ISO RGD:1601776 6480464 zoledronic acid results in increased expression of ST6GAL1 mRNA CTD PMID:20977926
Biological Process N-acetylneuraminate metabolic process ISO RGD:1601776 1624291 (PMID:23999306) RGD PMID:23999306 N-acetylneuraminate metabolic process ISS UniProtKB:P15907 1600115 GO_REF:0000024 UniProt GO_REF:0000024 N-acetylneuraminate metabolic process IEA UniProtKB:P15907 , ensembl:ENSP000001692981600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of chemotaxis IDA 10043143 RGD negative regulation of macrophage apoptotic process IDA 10043116 RGD positive regulation of mononuclear cell proliferation IDA 10043116 RGD protein glycosylation ISO RGD:736316 1624291 MGI:MGI:2387745 (MGI:MGI:2386347 , PMID:12068010) RGD MGI:MGI:2386347 , PMID:12068010 protein glycosylation IEA InterPro:IPR001675 1600115 GO_REF:0000002 InterPro GO_REF:0000002 protein N-linked glycosylation via asparagine ISO RGD:1601776 1624291 (PMID:23999306) RGD PMID:23999306 protein N-linked glycosylation via asparagine ISS UniProtKB:P15907 1600115 GO_REF:0000024 UniProt GO_REF:0000024 protein N-linked glycosylation via asparagine IEA UniProtKB:Q64685 , ensembl:ENSMUSP000000236011600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein N-linked glycosylation via asparagine IEA UniProtKB:P15907 , ensembl:ENSP000001692981600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein N-linked glycosylation via asparagine ISO RGD:736316 1624291 (MGI:MGI:6213409, PMID:22039275) RGD MGI:MGI:6213409 , PMID:22039275 protein sialylation IDA 10043116 RGD regulation of substrate adhesion-dependent cell spreading IDA 10043143 RGD response to ethanol IEP 10043140 RGD sialylation ISO RGD:1601776 1624291 (PMID:23999306) RGD PMID:23999306 sialylation ISS UniProtKB:P15907 1600115 GO_REF:0000024 UniProt GO_REF:0000024 sialylation IEA UniProtKB:P15907 , ensembl:ENSP000001692981600115 GO_REF:0000107 Ensembl GO_REF:0000107 sialylation IEA GO:0008373 1600115 GO_REF:0000108 GOC GO_REF:0000108 Cellular Component endoplasmic reticulum IDA 10043130 RGD extracellular region IEA UniProtKB-SubCell:SL-0243 1600115 GO_REF:0000044 UniProt GO_REF:0000044 Golgi apparatus IEA UniProtKB-KW:KW-0333 1600115 GO_REF:0000043 UniProt GO_REF:0000043 Golgi cisterna membrane IEA UniProtKB-SubCell:SL-0136 1600115 GO_REF:0000044 UniProt GO_REF:0000044 Golgi medial cisterna IDA 10043130 RGD Golgi membrane ISO RGD:1601776 1624291 (PMID:20378551) RGD PMID:20378551 Golgi membrane IEA UniProtKB:P15907 , ensembl:ENSP000001692981600115 GO_REF:0000107 Ensembl GO_REF:0000107 Golgi trans cisterna IDA 10043130 RGD integral component of membrane IEA UniProtKB-KW:KW-0812 1600115 GO_REF:0000043 UniProt GO_REF:0000043 Molecular Function beta-galactoside alpha-2,6-sialyltransferase activity ISO RGD:1601776 1624291 (PMID:23999306) RGD PMID:23999306 beta-galactoside alpha-2,6-sialyltransferase activity IBA MGI:MGI:108470 more ... 13792537 PMID:21873635 GO_Central beta-galactoside alpha-2,6-sialyltransferase activity ISS UniProtKB:P15907 1600115 GO_REF:0000024 UniProt GO_REF:0000024 beta-galactoside alpha-2,6-sialyltransferase activity IEA UniProtKB:Q64685 , ensembl:ENSMUSP000000236011600115 GO_REF:0000107 Ensembl GO_REF:0000107 beta-galactoside alpha-2,6-sialyltransferase activity IEA UniProtKB:P15907 , ensembl:ENSP000001692981600115 GO_REF:0000107 Ensembl GO_REF:0000107 beta-galactoside alpha-2,6-sialyltransferase activity ISO RGD:736316 1624291 MGI:MGI:2387745 (MGI:MGI:2386347 more ... RGD MGI:MGI:2386347 more ... protein binding ISO RGD:1601776 1624291 UniProtKB:P0C045 (PMID:16237761) RGD PMID:16237761 protein homodimerization activity ISO RGD:1601776 1624291 (PMID:20378551) RGD PMID:20378551 protein homodimerization activity IEA UniProtKB:P15907 , ensembl:ENSP000001692981600115 GO_REF:0000107 Ensembl GO_REF:0000107 sialyltransferase activity ISO RGD:1601776 1624291 (PMID:21081508) RGD PMID:21081508 sialyltransferase activity IEA InterPro:IPR001675 1600115 GO_REF:0000002 InterPro GO_REF:0000002 sialyltransferase activity IDA 10043130 RGD sialyltransferase activity ISO RGD:736316 1624291 (MGI:MGI:2677197, PMID:12966079) RGD MGI:MGI:2677197 , PMID:12966079
Gene-Chemical Interaction Annotations
