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Gene: St6gal1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1) Rattus norvegicus
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Symbol: St6gal1
Name: ST6 beta-galactoside alpha-2,6-sialyltransferase 1
Description: Exhibits sialyltransferase activity. Involved in several processes, including negative regulation of macrophage apoptotic process; protein sialylation; and regulation of substrate adhesion-dependent cell spreading. Localizes to the Golgi medial cisterna; Golgi trans cisterna; and endoplasmic reticulum. Used to study malignant glioma. Orthologous to human ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1); PARTICIPATES IN N-linked glycan biosynthetic pathway; O-linked glycan biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha 2,6-ST 1; beta galactoside alpha 2,6 sialyltransferase 1; beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; sialyltransferase 1; Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase); Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase); Siat1; ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6Gal I; ST6GalI
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01180,927,601 - 80,981,424 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1180,927,601 - 80,981,422 (-)Ensembl
Rnor_5.01179,754,201 - 79,808,024 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,723,269 - 79,765,645 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11179,780,860 - 79,789,781 (-)NCBI
Celera1176,402,694 - 76,445,042 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on St6gal1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3676
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.