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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3676
Species: Rattus norvegicus
RGD Object: Gene
Symbol: St6gal1
Name: ST6 beta-galactoside alpha-2,6-sialyltransferase 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
St6gal1affects response to substanceISOST6GAL1 (Homo sapiens)6480464CTDST6GAL1 protein affects the susceptibility to Oxygen deficiencyPMID:29475939
St6gal1multiple interactionsISOST6GAL1 (Homo sapiens)6480464CTDST6GAL1 protein affects the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; ST6GAL1 protein inhibits the reaction [Oxygen deficiency results in decreased expression of HIF1A mRNA]; ST6GAL1 protein promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; ST6GAL1 protein promotes the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA]; ST6GAL1 protein promotes the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; ST6GAL1 protein promotes the reaction [Oxygen deficiency results in increased expression of SLC2A3 mRNA]PMID:29475939
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