Tyrobp (transmembrane immune signaling adaptor Tyrobp)

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Gene: Tyrobp (transmembrane immune signaling adaptor Tyrobp) Rattus norvegicus

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Symbol:

Tyrobp

Name:

transmembrane immune signaling adaptor Tyrobp

RGD ID:

1303081

Description:

Predicted to have identical protein binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including myeloid cell activation involved in immune response; regulation of cytokine production; and regulation of lymphocyte activation. Predicted to localize to cell surface. Human ortholog(s) of this gene implicated in Nasu-Hakola disease. Orthologous to human TYROBP (transmembrane immune signaling adaptor TYROBP); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

DAP12; DNAX-activation protein 12; Karap; killer cell activating receptor-associated protein; LOC361537; Tyro protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein

Orthologs:

Homo sapiens (human) : TYROBP (transmembrane immune signaling adaptor TYROBP) HGNC Alliance
Mus musculus (house mouse) : Tyrobp (TYRO protein tyrosine kinase binding protein) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tyrobp (transmembrane immune signaling adaptor TYROBP)
Pan paniscus (bonobo/pygmy chimpanzee) : TYROBP (transmembrane immune signaling adaptor TYROBP)
Canis lupus familiaris (dog) : TYROBP (transmembrane immune signaling adaptor TYROBP)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tyrobp (transmembrane immune signaling adaptor TYROBP)
Sus scrofa (pig) : TYROBP (transmembrane immune signaling adaptor TYROBP)
Chlorocebus sabaeus (African green monkey) : TYROBP (transmembrane immune signaling adaptor TYROBP)
Heterocephalus glaber (naked mole-rat) : Tyrobp (transmembrane immune signaling adaptor TYROBP)

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	1	88,875,370 - 88,879,305 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	88,875,375 - 88,879,303 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	90,031,123 - 90,034,976 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	85,365,371 - 85,369,224 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	85,443,481 - 85,447,330 (+)	NCBI
Celera	1	80,045,174 - 80,049,027 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

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Comparative Map Data

QTLs in Region (Rnor_6.0)

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences

Protein Sequences

Transcriptome

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Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links

Nomenclature History

More on Tyrobp
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	1303081
Created:	2004-12-03
Species:	Rattus norvegicus
Last Modified:	2020-08-20
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - ClinVar

Imported Annotations - CTD

Imported Annotations - OMIM