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Gene: Prok2 (prokineticin 2) Rattus norvegicus
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Symbol: Prok2
Name: prokineticin 2
Description: Exhibits G protein-coupled receptor binding activity. Predicted to be involved in several processes, including activation of MAPK activity; angiogenesis; and cell population proliferation. Predicted to localize to the extracellular region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 4 with or without anosmia. Orthologous to human PROK2 (prokineticin 2); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bv8; homolog of mouse Bv8 (Bombina variegata 8 kDa); PK2; prokineticin 2 beta; prokineticin 2 precursor; prokineticin-2
Orthologs:
Homo sapiens (human) : PROK2 (prokineticin 2)  HGNC  Alliance
Mus musculus (house mouse) : Prok2 (prokineticin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prok2 (prokineticin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PROK2 (prokineticin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prok2 (prokineticin 2)
Sus scrofa (pig) : PROK2 (prokineticin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04132,157,556 - 132,171,244 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04196,648,637 - 196,662,531 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44134,561,300 - 134,574,487 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14134,806,140 - 134,819,328 (-)NCBI
Celera4121,207,301 - 121,220,343 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prok2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620280
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.