S1pr2 (sphingosine-1-phosphate receptor 2) - Rat Genome Database

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Gene: S1pr2 (sphingosine-1-phosphate receptor 2) Rattus norvegicus
Analyze
Symbol: S1pr2
Name: sphingosine-1-phosphate receptor 2
RGD ID: 68334
Description: Enables G protein-coupled peptide receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway; negative regulation of smooth muscle cell migration; and negative regulation of vascular associated smooth muscle cell proliferation. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 68. Orthologous to human S1PR2 (sphingosine-1-phosphate receptor 2); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: AGR16; Edg5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; G-protein coupled receptor 13; G-protein coupled receptor H218; Gpcr13; GPCR18; H218; S1P receptor 2; S1P receptor Edg-5; S1P2; snGPCR18; sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor Edg-5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2819,503,276 - 19,514,169 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,502,627 - 19,523,574 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx823,522,690 - 23,533,589 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0821,820,536 - 21,831,435 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0819,732,951 - 19,743,843 (-)NCBIRnor_WKY
Rnor_6.0821,984,914 - 21,995,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,984,914 - 21,995,806 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,041,266 - 22,061,702 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4819,989,867 - 20,000,759 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1819,989,866 - 20,000,759 (-)NCBI
Celera820,897,794 - 20,908,686 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids. An S, etal., FEBS Lett 1997 Nov 17;417(3):279-82.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Cloning and characterization of a putative G-protein coupled receptor potentially involved in development. MacLennan AJ, etal., Mol Cell Neurosci 1994 Jun;5(3):201-9.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Molecular cloning of a novel putative G protein-coupled receptor expressed in the cardiovascular system. Okazaki H, etal., Biochem Biophys Res Commun 1993 Feb 15;190(3):1104-9.
8. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2. Wang Y, etal., Circulation. 2018 Jul 3;138(1):48-63. doi: 10.1161/CIRCULATIONAHA.117.032398. Epub 2018 Feb 16.
Additional References at PubMed
PMID:10383399   PMID:11553273   PMID:15713536   PMID:18535287   PMID:19151362   PMID:19636535   PMID:21932398   PMID:22139303   PMID:22406263   PMID:22505286   PMID:23106337   PMID:24064301  
PMID:24700501   PMID:24851274   PMID:25575056   PMID:27317945   PMID:27814635   PMID:28493876   PMID:29266713   PMID:29401609   PMID:31603252   PMID:33452855   PMID:33880585   PMID:34224319  
PMID:35263212  


Genomics

Comparative Map Data
S1pr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2819,503,276 - 19,514,169 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,502,627 - 19,523,574 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx823,522,690 - 23,533,589 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0821,820,536 - 21,831,435 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0819,732,951 - 19,743,843 (-)NCBIRnor_WKY
Rnor_6.0821,984,914 - 21,995,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,984,914 - 21,995,806 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,041,266 - 22,061,702 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4819,989,867 - 20,000,759 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1819,989,866 - 20,000,759 (-)NCBI
Celera820,897,794 - 20,908,686 (-)NCBICelera
Cytogenetic Map8q13NCBI
S1PR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,221,433 - 10,231,331 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1910,221,433 - 10,231,331 (-)EnsemblGRCh38hg38GRCh38
GRCh371910,332,109 - 10,342,007 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,193,109 - 10,202,948 (-)NCBINCBI36Build 36hg18NCBI36
Build 341910,195,519 - 10,202,929NCBI
Celera1910,227,498 - 10,237,335 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,912,564 - 9,922,403 (-)NCBIHuRef
CHM1_11910,332,386 - 10,342,216 (-)NCBICHM1_1
T2T-CHM13v2.01910,347,578 - 10,357,458 (-)NCBIT2T-CHM13v2.0
S1pr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,877,248 - 20,888,089 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,873,657 - 20,888,077 (-)EnsemblGRCm39 Ensembl
GRCm38920,965,952 - 20,976,793 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,962,361 - 20,976,781 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,770,396 - 20,781,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,716,360 - 20,727,183 (-)NCBIMGSCv36mm8
Celera918,234,642 - 18,245,483 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.68NCBI
S1pr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,529,428 - 1,530,486 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,528,963 - 1,530,527 (-)NCBIChiLan1.0ChiLan1.0
S1PR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11910,436,094 - 10,443,955 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,436,502 - 10,437,563 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0199,771,888 - 9,781,944 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
S1PR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,855,505 - 50,862,985 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,860,591 - 50,861,649 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,725,039 - 50,732,522 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,376,931 - 51,384,414 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,376,966 - 51,384,411 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,583,043 - 50,590,527 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,012,253 - 51,019,735 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,252,973 - 51,260,455 (+)NCBIUU_Cfam_GSD_1.0
S1pr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,767,641 - 209,774,934 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936659579,867 - 586,885 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936659579,771 - 587,077 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
S1PR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,049,270 - 69,057,270 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1269,050,396 - 69,057,270 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,377,718 - 69,384,593 (-)NCBISscrofa10.2Sscrofa10.2susScr3
S1PR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,281,130 - 9,291,705 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl69,283,529 - 9,284,590 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607410,755,523 - 10,766,082 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
S1pr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,390,742 - 2,394,106 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,371,750 - 2,419,330 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in S1pr2
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:267
Count of miRNA genes:169
Interacting mature miRNAs:192
Transcripts:ENSRNOT00000028034
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat

Markers in Region
RH127910  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2819,503,411 - 19,503,601 (+)MAPPERmRatBN7.2
Rnor_6.0821,985,050 - 21,985,239NCBIRnor6.0
Rnor_5.0822,041,403 - 22,041,592UniSTSRnor5.0
RGSC_v3.4819,990,003 - 19,990,192UniSTSRGSC3.4
Celera820,897,930 - 20,898,119UniSTS
RH 3.4 Map8182.1UniSTS
Cytogenetic Map8q13UniSTS
UniSTS:474719  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2819,505,275 - 19,505,875 (+)MAPPERmRatBN7.2
Rnor_6.0821,986,914 - 21,987,513NCBIRnor6.0
Rnor_5.0822,043,267 - 22,043,866UniSTSRnor5.0
RGSC_v3.4819,991,867 - 19,992,466UniSTSRGSC3.4
Celera820,899,794 - 20,900,393UniSTS
Cytogenetic Map8q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 36 14 6 6 6 1 1 31 20 33 11 1
Low 1 7 43 35 13 35 7 10 43 15 8 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000028034   ⟹   ENSRNOP00000028034
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl819,503,263 - 19,523,574 (-)Ensembl
Rnor_6.0 Ensembl821,984,914 - 21,995,806 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107018   ⟹   ENSRNOP00000080559
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl819,502,627 - 19,514,332 (-)Ensembl
RefSeq Acc Id: NM_017192   ⟹   NP_058888
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2819,503,276 - 19,514,169 (-)NCBI
Rnor_6.0821,984,914 - 21,995,806 (-)NCBI
Rnor_5.0822,041,266 - 22,061,702 (-)NCBI
RGSC_v3.4819,989,867 - 20,000,759 (-)RGD
Celera820,897,794 - 20,908,686 (-)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_058888   ⟸   NM_017192
- UniProtKB: Q54AI6 (UniProtKB/Swiss-Prot),   P47752 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028034   ⟸   ENSRNOT00000028034
RefSeq Acc Id: ENSRNOP00000080559   ⟸   ENSRNOT00000107018
Protein Domains
G_PROTEIN_RECEP_F1_2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47752-F1-model_v2 AlphaFold P47752 1-352 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695770
Promoter ID:EPDNEW_R6294
Type:initiation region
Name:S1pr2_1
Description:sphingosine-1-phosphate receptor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0821,995,847 - 21,995,907EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68334 AgrOrtholog
BioCyc Gene G2FUF-31447 BioCyc
Ensembl Genes ENSRNOG00000020653 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000028034.3 UniProtKB/TrEMBL
  ENSRNOP00000080559 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000028034.5 UniProtKB/TrEMBL
  ENSRNOT00000107018 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro EDG5_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S1P_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29415 UniProtKB/Swiss-Prot
NCBI Gene 29415 ENTREZGENE
PANTHER PTHR22750:SF17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen S1pr2 PhenoGen
PRINTS EDG5RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S1PRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2QF47_RAT UniProtKB/TrEMBL
  P47752 ENTREZGENE
  Q54AI6 ENTREZGENE
  S1PR2_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q54AI6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-20 S1pr2  sphingosine-1-phosphate receptor 2  Edg5  endothelial differentiation, sphingolipid G-protein-coupled receptor, 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Edg5  endothelial differentiation, sphingolipid G-protein-coupled receptor, 5      Name updated 70584 APPROVED
2002-02-20 Edg5  endothelial differentiation, sphingolipid G-protein-coupled receptor, 5      Symbol and Name updated to reflect Human and Mouse nomenclature 70282 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains Src homology 2 domains 68254