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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621303
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp2b1
Name: ATPase plasma membrane Ca2+ transporting 1
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7354416480464CTDStreptozocin results in increased expression of ATP2B1 mRNA

PMID:29935216
multiple interactionsISORGD:7354416480464CTD[Streptozocin co-treated with bisphenol A] results in increased expression of ATP2B1 mRNA, [Streptozocin co-treated with octylphenol] results in increased expression of ATP2B1 mRNA

PMID:29935216
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.