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Gene: Sfrp2 (secreted frizzled-related protein 2) Rattus norvegicus
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Symbol: Sfrp2
Name: secreted frizzled-related protein 2
Description: Predicted to have several functions, including Wnt-protein binding activity; fibronectin binding activity; and molecular function regulator. Involved in negative regulation of canonical Wnt signaling pathway; positive regulation of canonical Wnt signaling pathway; and response to nutrient. Predicted to localize to the collagen-containing extracellular matrix and extracellular space. Biomarker of myocardial infarction. Orthologous to human SFRP2 (secreted frizzled related protein 2); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling pathway; INTERACTS WITH 17beta-estradiol; 2-amino-2-deoxy-D-glucopyranose; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: putative secreted frizzled related protein
Orthologs:
Homo sapiens (human) : SFRP2 (secreted frizzled related protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Sfrp2 (secreted frizzled-related protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sfrp2 (secreted frizzled related protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SFRP2 (secreted frizzled related protein 2)
Canis lupus familiaris (dog) : SFRP2 (secreted frizzled related protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sfrp2 (secreted frizzled related protein 2)
Sus scrofa (pig) : SFRP2 (secreted frizzled related protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02182,723,732 - 182,731,277 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02202,136,233 - 202,143,778 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42175,479,320 - 175,486,865 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12175,435,856 - 175,436,574 (+)NCBI
Celera2163,105,875 - 163,113,424 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sfrp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735163
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.