Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Derl3 (derlin 3) Rattus norvegicus
Analyze
Symbol: Derl3
Name: derlin 3
Description: Predicted to have misfolded protein binding activity and ubiquitin-specific protease binding activity. Predicted to be involved in cellular protein metabolic process; endoplasmic reticulum unfolded protein response; and negative regulation of retrograde protein transport, ER to cytosol. Predicted to colocalize with the signal recognition particle and signal recognition particle receptor complex. Orthologous to human DERL3 (derlin 3); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Der1-like domain family, member 3; derlin-3; LOC690315; similar to Der1-like domain family, member 3
Orthologs:
Homo sapiens (human) : DERL3 (derlin 3)  HGNC  Alliance
Mus musculus (house mouse) : Derl3 (Der1-like domain family, member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Derl3 (derlin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DERL3 (derlin 3)
Canis lupus familiaris (dog) : DERL3 (derlin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Derl3 (derlin 3)
Sus scrofa (pig) : DERL3 (derlin 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02013,692,102 - 13,707,645 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,704,314 - 13,706,205 (-)Ensembl
Rnor_5.02015,858,297 - 15,863,183 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,163,287 - 13,165,848 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2014,255,751 - 14,258,312 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Derl3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1597373
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.