Symbol:
Ctss
Name:
cathepsin S
RGD ID:
621513
Description:
Enables cysteine-type peptidase activity. Involved in bone resorption and metanephros development. Located in cell surface. Biomarker of intracranial aneurysm. Human ortholog(s) of this gene implicated in neuropathy. Orthologous to human CTSS (cathepsin S); PARTICIPATES IN antigen processing and presentation pathway; phagocytosis pathway; tuberculosis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type:
protein-coding
RefSeq Status:
VALIDATED
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
CTSS (cathepsin S) HGNC
HomoloGene, NCBI, Panther
Mus musculus (house mouse):
Ctss (cathepsin S) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ctss (cathepsin S) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
CTSS (cathepsin S) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
CTSS (cathepsin S) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ctss (cathepsin S) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
CTSS (cathepsin S) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
CTSS (cathepsin S) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ctss (cathepsin S) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
DEFA5 (defensin alpha 5) HGNC
OMA
Homo sapiens (human):
DEFA4 (defensin alpha 4) HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Ctss (cathepsin S)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
CTSS (cathepsin S)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ctss2.1 (cathepsin S, ortholog2, tandem duplicate 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ctss2.2 (cathepsin S, ortholog 2, tandem duplicate 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
Y71H2AM.25
Alliance
DIOPT (Ensembl Compara|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
CG11459
Alliance
DIOPT (OMA|PANTHER)
Xenopus tropicalis (tropical clawed frog):
ctss
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 185,775,316 - 185,803,440 (+) NCBI GRCr8 mRatBN7.2 2 183,086,437 - 183,114,483 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 183,086,437 - 183,114,483 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 2 190,751,075 - 190,779,335 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 188,546,398 - 188,574,853 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 183,383,602 - 183,411,862 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 197,655,780 - 197,679,768 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 197,655,786 - 197,679,458 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 2 217,144,866 - 217,169,058 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 2 190,425,290 - 190,466,877 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 2 190,385,391 - 190,429,631 (+) NCBI Celera 2 175,621,979 - 175,645,341 (+) NCBI Celera Cytogenetic Map 2 q34 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Ctss Rat (1->4)-beta-D-glucan multiple interactions ISO Ctss (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CTSS mRNA CTD PMID:36331819 Ctss Rat (R)-lipoic acid decreases expression ISO Ctss (Mus musculus) 6480464 Thioctic Acid results in decreased expression of CTSS mRNA CTD PMID:19555370 Ctss Rat 1,1-dichloroethene increases expression ISO Ctss (Mus musculus) 6480464 vinylidene chloride results in increased expression of CTSS mRNA CTD PMID:26682919 Ctss Rat 1,2-dimethylhydrazine multiple interactions ISO Ctss (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CTSS mRNA CTD PMID:22206623 Ctss Rat 1,2-dimethylhydrazine decreases expression ISO Ctss (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of CTSS mRNA CTD PMID:22206623 Ctss Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of CTSS mRNA CTD PMID:18289764 and PMID:25380136 Ctss Rat 17alpha-ethynylestradiol increases expression ISO Ctss (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of CTSS mRNA CTD PMID:12072388 Ctss Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of CTSS mRNA CTD PMID:12655037 more ... Ctss Rat 17alpha-ethynylestradiol multiple interactions ISO Ctss (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CTSS mRNA CTD PMID:17942748 Ctss Rat 17beta-estradiol affects expression ISO Ctss (Mus musculus) 6480464 Estradiol affects the expression of CTSS mRNA CTD PMID:15598610 Ctss Rat 17beta-estradiol decreases expression ISO Ctss (Mus musculus) 6480464 Estradiol results in decreased expression of CTSS mRNA CTD PMID:39298647 Ctss Rat 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CTSS mRNA CTD PMID:32741896 Ctss Rat 17beta-estradiol increases expression ISO Ctss (Mus musculus) 6480464 Estradiol results in increased expression of CTSS mRNA CTD PMID:19484750 Ctss Rat 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CTSS mRNA CTD PMID:32741896 Ctss Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ctss (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CTSS mRNA CTD PMID:17942748 Ctss Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CTSS mRNA CTD PMID:34747641 Ctss Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ctss (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CTSS mRNA CTD PMID:21570461 more ... Ctss Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO CTSS (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of CTSS mRNA CTD PMID:20106945 and PMID:21632981 Ctss Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Ctss (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Ctss Rat 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of CTSS mRNA CTD PMID:14600272 Ctss Rat 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of CTSS mRNA CTD PMID:28522335 Ctss Rat 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of CTSS mRNA CTD PMID:19162173 Ctss Rat 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of CTSS mRNA CTD PMID:25380136 and PMID:30723492 Ctss Rat 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of CTSS mRNA CTD PMID:18289764 Ctss Rat 4,4'-sulfonyldiphenol increases expression ISO Ctss (Mus musculus) 6480464 bisphenol S results in increased expression of CTSS mRNA CTD PMID:30951980 Ctss Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CTSS mRNA CTD PMID:36041667 Ctss Rat 4,4'-sulfonyldiphenol affects expression ISO Ctss (Mus musculus) 6480464 bisphenol S affects the expression of CTSS mRNA CTD PMID:39298647 Ctss Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTSS mRNA CTD PMID:14600272 Ctss Rat 4-hydroxy-TEMPO decreases expression ISO Ctss (Mus musculus) 6480464 tempol results in decreased expression of CTSS mRNA CTD PMID:19555370 Ctss Rat 4-hydroxyphenyl retinamide decreases expression ISO Ctss (Mus musculus) 6480464 Fenretinide results in decreased expression of CTSS mRNA CTD PMID:28973697 Ctss Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of CTSS mRNA CTD PMID:31881176 Ctss Rat actinomycin D multiple interactions ISO CTSS (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of CTSS protein CTD PMID:38460933 Ctss Rat aflatoxin B1 increases methylation ISO CTSS (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of CTSS gene CTD PMID:27153756 Ctss Rat aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of CTSS mRNA CTD PMID:33354967 Ctss Rat all-trans-retinoic acid increases expression ISO CTSS (Homo sapiens) 6480464 Tretinoin results in increased expression of CTSS mRNA CTD PMID:23830798 and PMID:33167477 Ctss Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CTSS mRNA CTD PMID:16483693 Ctss Rat amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of CTSS mRNA CTD PMID:30779732 Ctss Rat anagliptin multiple interactions ISO CTSS (Homo sapiens) 6480464 anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of CTSS mRNA] CTD PMID:31586451 Ctss Rat antirheumatic drug decreases expression ISO CTSS (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of CTSS mRNA CTD PMID:24449571 Ctss Rat aristolochic acid A multiple interactions EXP 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of CTSS mRNA CTD PMID:23912714 Ctss Rat aristolochic acid A increases expression ISO CTSS (Homo sapiens) 6480464 aristolochic acid I results in increased expression of CTSS mRNA CTD PMID:33212167 Ctss Rat arsenous acid increases expression ISO CTSS (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of CTSS mRNA CTD PMID:19101991 Ctss Rat asperphenamate multiple interactions ISO CTSS (Homo sapiens) 6480464 asperphenamate analog binds to and results in decreased activity of CTSS protein CTD PMID:30253340 Ctss Rat astaxanthin decreases expression ISO Ctss (Mus musculus) 6480464 astaxanthine results in decreased expression of CTSS mRNA CTD PMID:19555370 Ctss Rat bacitracin increases expression EXP 6480464 Bacitracin results in increased expression of CTSS mRNA CTD PMID:18289764 Ctss Rat benzo[a]pyrene increases expression ISO Ctss (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of CTSS mRNA CTD PMID:22228805 Ctss Rat benzo[a]pyrene increases expression ISO CTSS (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of CTSS mRNA CTD PMID:35870112 Ctss Rat benzo[b]fluoranthene increases expression ISO Ctss (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of CTSS mRNA CTD PMID:26377693 Ctss Rat beta-hexachlorocyclohexane increases expression ISO Ctss (Mus musculus) 6480464 beta-hexachlorocyclohexane results in increased expression of CTSS mRNA CTD PMID:25270620 Ctss Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Ctss (Mus musculus) 6480464 Diethylhexyl Phthalate promotes the reaction [Dietary Fats results in increased expression of CTSS mRNA] CTD PMID:34303773 Ctss Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CTSS mRNA CTD PMID:25181051 and PMID:34947998 Ctss Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CTSS mRNA CTD PMID:36041667 Ctss Rat bisphenol A decreases expression ISO Ctss (Mus musculus) 6480464 bisphenol A results in decreased expression of CTSS mRNA CTD PMID:35598803 Ctss Rat bisphenol A increases expression ISO Ctss (Mus musculus) 6480464 bisphenol A results in increased expression of CTSS mRNA CTD PMID:38701888 Ctss Rat bisphenol F increases expression ISO Ctss (Mus musculus) 6480464 bisphenol F results in increased expression of CTSS mRNA CTD PMID:30951980 and PMID:38685157 Ctss Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CTSS mRNA CTD PMID:36041667 Ctss Rat bleomycin A2 increases expression ISO CTSS (Homo sapiens) 6480464 Bleomycin results in increased expression of CTSS mRNA CTD PMID:19101991 Ctss Rat Brusatol multiple interactions EXP 6480464 brusatol inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CTSS mRNA] CTD PMID:34695510 Ctss Rat buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of CTSS mRNA CTD PMID:24136188 Ctss Rat cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CTSS mRNA more ... CTD PMID:34695510 Ctss Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of CTSS mRNA CTD PMID:25993096 Ctss Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CTSS mRNA more ... CTD PMID:34695510 Ctss Rat cadmium dichloride increases expression ISO Ctss (Mus musculus) 6480464 Cadmium Chloride results in increased expression of CTSS mRNA CTD PMID:30030080 Ctss Rat calcium atom multiple interactions ISO CTSS (Homo sapiens) 6480464 [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium more ... CTD PMID:25833952 Ctss Rat calcium(0) multiple interactions ISO CTSS (Homo sapiens) 6480464 [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium more ... CTD PMID:25833952 Ctss Rat carbon nanotube affects expression ISO Ctss (Mus musculus) 6480464 Nanotubes and Carbon affects the expression of CTSS mRNA CTD PMID:23845593 Ctss Rat carbon nanotube increases expression ISO Ctss (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 Ctss Rat CGP 52608 multiple interactions ISO CTSS (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to CTSS gene] CTD PMID:28238834 Ctss Rat chlormequat chloride decreases expression EXP 6480464 Chlormequat results in decreased expression of CTSS protein CTD PMID:34958886 Ctss Rat chlorpyrifos increases expression ISO Ctss (Mus musculus) 6480464 Chlorpyrifos results in increased expression of CTSS mRNA CTD PMID:27737797 Ctss Rat choline multiple interactions ISO Ctss (Mus musculus) 6480464 [Dietary Fats co-treated with Choline deficiency] results in increased expression of CTSS mRNA more ... CTD PMID:20938992 and PMID:29246445 Ctss Rat chondroitin sulfate multiple interactions ISO CTSS (Homo sapiens) 6480464 Chondroitin Sulfates inhibits the reaction [CTSS protein results in increased degradation of CXCL10 protein] more ... CTD PMID:25833952 Ctss Rat chromium(6+) affects expression ISO Ctss (Mus musculus) 6480464 chromium hexavalent ion affects the expression of CTSS mRNA CTD PMID:28472532 Ctss Rat cisplatin decreases expression ISO CTSS (Homo sapiens) 6480464 Cisplatin results in decreased expression of CTSS mRNA CTD PMID:27594783 Ctss Rat cisplatin multiple interactions ISO CTSS (Homo sapiens) 6480464 [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of CTSS mRNA CTD PMID:30871063 Ctss Rat cisplatin increases expression ISO CTSS (Homo sapiens) 6480464 Cisplatin results in increased expression of CTSS mRNA CTD PMID:27392435 Ctss Rat clofibrate multiple interactions ISO Ctss (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CTSS mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CTSS mRNA] CTD PMID:17585979 Ctss Rat coenzyme Q10 decreases expression ISO Ctss (Mus musculus) 6480464 coenzyme Q10 results in decreased expression of CTSS mRNA CTD PMID:19555370 Ctss Rat copper atom decreases expression EXP 6480464 Copper results in decreased expression of CTSS mRNA CTD PMID:30556269 Ctss Rat copper atom multiple interactions ISO CTSS (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of CTSS mRNA CTD PMID:30911355 Ctss Rat copper(0) decreases expression EXP 6480464 Copper results in decreased expression of CTSS mRNA CTD PMID:30556269 Ctss Rat copper(0) multiple interactions ISO CTSS (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of CTSS mRNA CTD PMID:30911355 Ctss Rat corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of CTSS mRNA CTD PMID:15755911 Ctss Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of CTSS mRNA CTD PMID:27523638 Ctss Rat curcumin decreases expression ISO Ctss (Mus musculus) 6480464 Curcumin results in decreased expression of CTSS mRNA CTD PMID:19555370 Ctss Rat cyclosporin A increases expression ISO CTSS (Homo sapiens) 6480464 Cyclosporine results in increased expression of CTSS mRNA CTD PMID:27989131 Ctss Rat deguelin decreases expression ISO CTSS (Homo sapiens) 6480464 deguelin results in decreased expression of CTSS mRNA CTD PMID:33512557 Ctss Rat dextran sulfate decreases expression ISO Ctss (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of CTSS protein CTD PMID:32272095 Ctss Rat dextran sulfate multiple interactions ISO Ctss (Mus musculus) 6480464 Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CTSS protein] CTD PMID:32272095 Ctss Rat diarsenic trioxide increases expression ISO CTSS (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of CTSS mRNA CTD PMID:19101991 Ctss Rat Dibutyl phosphate affects expression ISO CTSS (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of CTSS mRNA CTD PMID:37042841 Ctss Rat diclofenac increases expression ISO Ctss (Mus musculus) 6480464 Diclofenac results in increased expression of CTSS mRNA CTD PMID:26934552 Ctss Rat diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of CTSS mRNA CTD PMID:36653537 Ctss Rat diquat decreases expression ISO Ctss (Mus musculus) 6480464 Diquat results in decreased expression of CTSS mRNA CTD PMID:36851058 Ctss Rat diuron decreases expression EXP 6480464 Diuron results in decreased expression of CTSS mRNA CTD PMID:25152437 Ctss Rat doramapimod decreases expression ISO Ctss (Mus musculus) 6480464 doramapimod results in decreased expression of CTSS mRNA CTD PMID:21328587 Ctss Rat doxorubicin affects response to substance ISO CTSS (Homo sapiens) 6480464 CTSS protein affects the susceptibility to Doxorubicin CTD PMID:16217747 Ctss Rat doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of CTSS mRNA CTD PMID:32289291 Ctss Rat doxorubicin decreases expression ISO CTSS (Homo sapiens) 6480464 Doxorubicin results in decreased expression of CTSS mRNA CTD PMID:29803840 Ctss Rat doxorubicin increases expression ISO Ctss (Mus musculus) 6480464 Doxorubicin results in increased expression of CTSS mRNA CTD PMID:15033991 and PMID:25896364 Ctss Rat epoxiconazole increases expression ISO Ctss (Mus musculus) 6480464 epoxiconazole results in increased expression of CTSS mRNA CTD PMID:35436446 Ctss Rat ethanol decreases response to substance ISO Ctss (Mus musculus) 6480464 CTSS gene mutant form results in decreased susceptibility to Ethanol CTD PMID:21309947 Ctss Rat ethanol increases expression ISO Ctss (Mus musculus) 6480464 Ethanol results in increased expression of CTSS mRNA CTD PMID:30319688 Ctss Rat ethanol multiple interactions ISO Ctss (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of CTSS mRNA CTD PMID:30517762 Ctss Rat flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of CTSS mRNA CTD PMID:24136188 Ctss Rat folic acid multiple interactions ISO Ctss (Mus musculus) 6480464 [1 more ... CTD PMID:20938992 and PMID:22206623 Ctss Rat folpet decreases expression ISO Ctss (Mus musculus) 6480464 folpet results in decreased expression of CTSS mRNA CTD PMID:31558096 Ctss Rat fumonisin B1 increases expression ISO Ctss (Mus musculus) 6480464 fumonisin B1 results in increased expression of CTSS mRNA CTD PMID:16221962 Ctss Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CTSS mRNA CTD PMID:18289764 and PMID:22061828 Ctss Rat glycolaldehyde decreases activity ISO CTSS (Homo sapiens) 6480464 glycolaldehyde results in decreased activity of CTSS protein CTD PMID:16671891 Ctss Rat glyoxal decreases activity ISO CTSS (Homo sapiens) 6480464 Glyoxal results in decreased activity of CTSS protein CTD PMID:16671891 Ctss Rat graphene oxide increases expression ISO Ctss (Mus musculus) 6480464 graphene oxide analog results in increased expression of CTSS mRNA and graphene oxide results in increased expression of CTSS mRNA CTD PMID:33227293 Ctss Rat hydrogen peroxide increases expression ISO CTSS (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of CTSS mRNA CTD PMID:19101991 and PMID:31586451 Ctss Rat hydrogen peroxide multiple interactions ISO CTSS (Homo sapiens) 6480464 anagliptin inhibits the reaction [Hydrogen Peroxide results in increased expression of CTSS mRNA] CTD PMID:31586451 Ctss Rat imiquimod increases activity ISO Ctss (Mus musculus) 6480464 Imiquimod results in increased activity of CTSS protein CTD PMID:22916010 Ctss Rat indometacin increases expression EXP 6480464 Indomethacin results in increased expression of CTSS mRNA CTD PMID:36868495 Ctss Rat kainic acid increases expression ISO Ctss (Mus musculus) 6480464 Kainic Acid results in increased expression of CTSS mRNA and Kainic Acid results in increased expression of CTSS protein CTD PMID:17997037 Ctss Rat ketamine increases expression EXP 6480464 Ketamine results in increased expression of CTSS mRNA CTD PMID:20080153 Ctss Rat ketoconazole affects expression EXP 6480464 Ketoconazole affects the expression of CTSS mRNA CTD PMID:18289764 Ctss Rat L-methionine multiple interactions ISO Ctss (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTSS mRNA CTD PMID:20938992 Ctss Rat lipoic acid decreases expression ISO Ctss (Mus musculus) 6480464 Thioctic Acid results in decreased expression of CTSS mRNA CTD PMID:19555370 Ctss Rat lipopolysaccharide increases expression ISO Ctss (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of CTSS mRNA CTD PMID:27339419 Ctss Rat lycopene decreases expression ISO Ctss (Mus musculus) 6480464 lycopene results in decreased expression of CTSS mRNA CTD PMID:19555370 Ctss Rat methotrexate affects expression ISO Ctss (Mus musculus) 6480464 Methotrexate affects the expression of CTSS mRNA CTD PMID:18502557 Ctss Rat methotrexate decreases expression ISO CTSS (Homo sapiens) 6480464 Methotrexate results in decreased expression of CTSS mRNA CTD PMID:17400583 Ctss Rat methylglyoxal decreases activity ISO CTSS (Homo sapiens) 6480464 Pyruvaldehyde results in decreased activity of CTSS protein CTD PMID:16671891 Ctss Rat mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of CTSS mRNA CTD PMID:25972201 Ctss Rat N-nitrosodiethylamine increases expression ISO Ctss (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of CTSS mRNA CTD PMID:17942915 Ctss Rat N-nitrosodiethylamine multiple interactions ISO Ctss (Mus musculus) 6480464 MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CTSS mRNA] CTD PMID:17942915 Ctss Rat N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of CTSS mRNA CTD PMID:14600272 and PMID:25380136 Ctss Rat nickel atom increases expression ISO CTSS (Homo sapiens) 6480464 Nickel results in increased expression of CTSS mRNA CTD PMID:24768652 and PMID:25583101 Ctss Rat nickel subsulfide increases expression EXP 6480464 nickel subsulfide results in increased expression of CTSS mRNA CTD PMID:21086188 Ctss Rat nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of CTSS mRNA CTD PMID:24136188 Ctss Rat Nutlin-3 multiple interactions ISO CTSS (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of CTSS protein CTD PMID:38460933 Ctss Rat O-acetyl-L-carnitine decreases expression ISO Ctss (Mus musculus) 6480464 Acetylcarnitine results in decreased expression of CTSS mRNA CTD PMID:19555370 Ctss Rat oligopeptide decreases expression ISO CTSS (Homo sapiens) 6480464 Oligopeptides analog results in decreased expression of CTSS protein CTD PMID:24875536 Ctss Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of CTSS mRNA CTD PMID:25729387 Ctss Rat ozone multiple interactions ISO Ctss (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which affects the expression of CTSS mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of CTSS mRNA CTD PMID:34911549 Ctss Rat ozone multiple interactions ISO CTSS (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of CTSS mRNA CTD PMID:35430440 Ctss Rat paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of CTSS mRNA CTD PMID:18754875 Ctss Rat paracetamol multiple interactions ISO Ctss (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CTSS mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CTSS mRNA] CTD PMID:17585979 Ctss Rat paracetamol decreases expression ISO CTSS (Homo sapiens) 6480464 Acetaminophen results in decreased expression of CTSS mRNA CTD PMID:21420995 and PMID:29067470 Ctss Rat paracetamol affects expression ISO Ctss (Mus musculus) 6480464 Acetaminophen affects the expression of CTSS mRNA CTD PMID:17562736 Ctss Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Ctss (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CTSS mRNA CTD PMID:36331819 Ctss Rat phenobarbital multiple interactions ISO Ctss (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of CTSS mRNA] CTD PMID:19482888 Ctss Rat phenobarbital decreases expression ISO Ctss (Mus musculus) 6480464 Phenobarbital results in decreased expression of CTSS mRNA CTD PMID:19482888 Ctss Rat picoxystrobin decreases expression ISO CTSS (Homo sapiens) 6480464 picoxystrobin results in decreased expression of CTSS mRNA CTD PMID:33512557 Ctss Rat pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of CTSS mRNA CTD PMID:19162173 Ctss Rat potassium chromate decreases expression ISO CTSS (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of CTSS mRNA CTD PMID:22714537 Ctss Rat pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of CTSS mRNA CTD PMID:19162173 Ctss Rat resveratrol multiple interactions EXP 6480464 [resveratrol co-treated with Streptozocin] results in increased expression of CTSS mRNA CTD PMID:25905778 Ctss Rat serpentine asbestos increases expression ISO CTSS (Homo sapiens) 6480464 Asbestos and Serpentine results in increased expression of CTSS mRNA CTD PMID:24160326 Ctss Rat serpentine asbestos increases expression ISO Ctss (Mus musculus) 6480464 Asbestos and Serpentine results in increased expression of CTSS mRNA CTD PMID:16251409 Ctss Rat silicon dioxide decreases expression ISO CTSS (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of CTSS mRNA CTD PMID:25895662 Ctss Rat silicon dioxide increases expression ISO CTSS (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of CTSS mRNA CTD PMID:34766707 Ctss Rat silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of CTSS mRNA CTD PMID:32721576 Ctss Rat simvastatin multiple interactions ISO Ctss (Mus musculus) 6480464 Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol more ... CTD PMID:20835264 Ctss Rat sodium arsenite affects expression ISO CTSS (Homo sapiens) 6480464 sodium arsenite affects the expression of CTSS mRNA CTD PMID:20816728 Ctss Rat sodium arsenite decreases expression ISO Ctss (Mus musculus) 6480464 sodium arsenite results in decreased expression of CTSS mRNA CTD PMID:37668303 Ctss Rat sodium arsenite increases expression ISO CTSS (Homo sapiens) 6480464 sodium arsenite results in increased expression of CTSS mRNA CTD PMID:38568856 Ctss Rat streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of CTSS mRNA CTD PMID:16684804 Ctss Rat streptozocin multiple interactions EXP 6480464 [resveratrol co-treated with Streptozocin] results in increased expression of CTSS mRNA and vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA] CTD PMID:16684804 and PMID:25905778 Ctss Rat succimer multiple interactions ISO CTSS (Homo sapiens) 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CTSS mRNA CTD PMID:26378955 Ctss Rat testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CTSS mRNA CTD PMID:32741896 Ctss Rat testosterone enanthate affects expression ISO CTSS (Homo sapiens) 6480464 testosterone enanthate affects the expression of CTSS mRNA CTD PMID:17440010 Ctss Rat tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of CTSS mRNA CTD PMID:15963342 Ctss Rat tetrachloromethane multiple interactions ISO Ctss (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of CTSS mRNA CTD PMID:30517762 Ctss Rat tetrachloromethane increases expression ISO Ctss (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of CTSS mRNA CTD PMID:27339419 more ... Ctss Rat thifluzamide decreases expression ISO CTSS (Homo sapiens) 6480464 thifluzamide results in decreased expression of CTSS mRNA CTD PMID:33512557 Ctss Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CTSS mRNA CTD PMID:34492290 Ctss Rat titanium dioxide affects expression ISO Ctss (Mus musculus) 6480464 titanium dioxide affects the expression of CTSS mRNA CTD PMID:27760801 Ctss Rat titanium dioxide increases expression ISO Ctss (Mus musculus) 6480464 titanium dioxide results in increased expression of CTSS mRNA CTD PMID:23557971 Ctss Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of CTSS mRNA CTD PMID:25729387 Ctss Rat tremolite asbestos increases expression ISO Ctss (Mus musculus) 6480464 tremolite results in increased expression of CTSS mRNA CTD PMID:29279043 Ctss Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of CTSS mRNA CTD PMID:33387578 Ctss Rat triphenyl phosphate affects expression ISO CTSS (Homo sapiens) 6480464 triphenyl phosphate affects the expression of CTSS mRNA CTD PMID:37042841 Ctss Rat triptonide increases expression ISO Ctss (Mus musculus) 6480464 triptonide results in increased expression of CTSS mRNA CTD PMID:33045310 Ctss Rat valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of CTSS mRNA CTD PMID:24136188 Ctss Rat valproic acid decreases expression ISO CTSS (Homo sapiens) 6480464 Valproic Acid results in decreased expression of CTSS mRNA CTD PMID:29154799 Ctss Rat valsartan decreases expression ISO CTSS (Homo sapiens) 6480464 Valsartan results in decreased expression of CTSS mRNA CTD PMID:22768174 Ctss Rat vanadyl sulfate multiple interactions EXP 6480464 vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA] CTD PMID:16684804 Ctss Rat vancomycin decreases expression ISO Ctss (Mus musculus) 6480464 Vancomycin results in decreased expression of CTSS mRNA CTD PMID:18930951 Ctss Rat vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of CTSS mRNA CTD PMID:18289764 Ctss Rat vincaleukoblastine increases expression EXP 6480464 Vinblastine results in increased expression of CTSS mRNA CTD PMID:20624997 Ctss Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of CTSS mRNA CTD PMID:23034163 Ctss Rat Yessotoxin increases expression ISO CTSS (Homo sapiens) 6480464 yessotoxin analog results in increased expression of CTSS mRNA CTD PMID:30679557 Ctss Rat zoledronic acid increases expression ISO CTSS (Homo sapiens) 6480464 zoledronic acid results in increased expression of CTSS mRNA CTD PMID:24714768
Imported Annotations - KEGG (archival)
(1->4)-beta-D-glucan (ISO) (R)-lipoic acid (ISO) 1,1-dichloroethene (ISO) 1,2-dimethylhydrazine (ISO) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (EXP,ISO) 17beta-estradiol 3-benzoate (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2-nitrofluorene (EXP) 3-chloropropane-1,2-diol (EXP) 3H-1,2-dithiole-3-thione (EXP) 4,4'-diaminodiphenylmethane (EXP) 4,4'-sulfonyldiphenol (EXP,ISO) 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP) 4-hydroxy-TEMPO (ISO) 4-hydroxyphenyl retinamide (ISO) acetamide (EXP) actinomycin D (ISO) aflatoxin B1 (EXP,ISO) all-trans-retinoic acid (ISO) ammonium chloride (EXP) amphetamine (EXP) anagliptin (ISO) antirheumatic drug (ISO) aristolochic acid A (EXP,ISO) arsenous acid (ISO) asperphenamate (ISO) astaxanthin (ISO) bacitracin (EXP) benzo[a]pyrene (ISO) benzo[b]fluoranthene (ISO) beta-hexachlorocyclohexane (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol F (EXP,ISO) bleomycin A2 (ISO) Brusatol (EXP) buspirone (EXP) cadmium atom (EXP) cadmium dichloride (EXP,ISO) calcium atom (ISO) calcium(0) (ISO) carbon nanotube (ISO) CGP 52608 (ISO) chlormequat chloride (EXP) chlorpyrifos (ISO) choline (ISO) chondroitin sulfate (ISO) chromium(6+) (ISO) cisplatin (ISO) clofibrate (ISO) coenzyme Q10 (ISO) copper atom (EXP,ISO) copper(0) (EXP,ISO) corticosterone (EXP) Cuprizon (EXP) curcumin (ISO) cyclosporin A (ISO) deguelin (ISO) dextran sulfate (ISO) diarsenic trioxide (ISO) Dibutyl phosphate (ISO) diclofenac (ISO) diethylstilbestrol (EXP) diquat (ISO) diuron (EXP) doramapimod (ISO) doxorubicin (EXP,ISO) epoxiconazole (ISO) ethanol (ISO) flutamide (EXP) folic acid (ISO) folpet (ISO) fumonisin B1 (ISO) gentamycin (EXP) glycolaldehyde (ISO) glyoxal (ISO) graphene oxide (ISO) hydrogen peroxide (ISO) imiquimod (ISO) indometacin (EXP) kainic acid (ISO) ketamine (EXP) ketoconazole (EXP) L-methionine (ISO) lipoic acid (ISO) lipopolysaccharide (ISO) lycopene (ISO) methotrexate (ISO) methylglyoxal (ISO) mifepristone (EXP) N-nitrosodiethylamine (ISO) N-nitrosodimethylamine (EXP) nickel atom (ISO) nickel subsulfide (EXP) nimesulide (EXP) Nutlin-3 (ISO) O-acetyl-L-carnitine (ISO) oligopeptide (ISO) oxaliplatin (EXP) ozone (ISO) paclitaxel (EXP) paracetamol (ISO) perfluorooctane-1-sulfonic acid (ISO) phenobarbital (ISO) picoxystrobin (ISO) pirinixic acid (EXP) potassium chromate (ISO) pregnenolone 16alpha-carbonitrile (EXP) resveratrol (EXP) serpentine asbestos (ISO) silicon dioxide (EXP,ISO) simvastatin (ISO) sodium arsenite (ISO) streptozocin (EXP) succimer (ISO) testosterone (EXP) testosterone enanthate (ISO) tetrachloromethane (EXP,ISO) thifluzamide (ISO) thioacetamide (EXP) titanium dioxide (ISO) topotecan (EXP) tremolite asbestos (ISO) trichloroethene (EXP) triphenyl phosphate (ISO) triptonide (ISO) valdecoxib (EXP) valproic acid (ISO) valsartan (ISO) vanadyl sulfate (EXP) vancomycin (EXP,ISO) vincaleukoblastine (EXP) vinclozolin (EXP) Yessotoxin (ISO) zoledronic acid (ISO)
1.
Increased expression of the lysosomal protease cathepsin S in hippocampal microglia following kainate-induced seizures.
Akahoshi N, etal., Neurosci Lett. 2007 Dec 18;429(2-3):136-41. Epub 2007 Oct 18.
2.
Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms.
Aoki T, etal., Stroke. 2008 Sep;39(9):2603-10. Epub 2008 Jul 17.
3.
Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles.
Baker CA, etal., J Virol. 2002 Nov;76(21):10905-13.
4.
Therapeutic dosing of an orally active, selective cathepsin S inhibitor suppresses disease in models of autoimmunity.
Baugh M, etal., J Autoimmun. 2011 May;36(3-4):201-9. Epub 2011 Mar 24.
5.
Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice.
Cattaruzza F, etal., Gastroenterology. 2011 Nov;141(5):1864-74.e1-3. Epub 2011 Jul 28.
6.
Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin alphanubeta3.
Cheng XW, etal., Am J Pathol. 2006 Feb;168(2):685-94.
7.
Spinal cathepsin S and fractalkine contribute to chronic pain in collagen induced arthritis.
Clark AK, etal., Arthritis Rheum. 2011 Dec 27. doi: 10.1002/art.34351.
8.
Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain.
Clark AK, etal., Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10655-60. Epub 2007 Jun 5.
9.
An orally active reversible inhibitor of cathepsin S inhibits human trans vivo delayed-type hypersensitivity.
Desai SN, etal., Eur J Pharmacol. 2006 May 24;538(1-3):168-74. Epub 2006 Mar 28.
10.
Genetic variation associated with bortezomib-induced peripheral neuropathy.
Favis R, etal., Pharmacogenet Genomics. 2011 Mar;21(3):121-9.
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
12.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
13.
Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice.
Hao HP, etal., J Neurosci Res. 2007 Aug 1;85(10):2196-206.
14.
Cathepsins and their endogenous inhibitors cystatins: expression and modulation in multiple sclerosis.
Haves-Zburof D, etal., J Cell Mol Med. 2011 Nov;15(11):2421-9. doi: 10.1111/j.1582-4934.2010.01229.x.
15.
Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis.
Johnson EM, etal., J Virol. 2009 Oct;83(19):9630-40. Epub 2009 Jul 29.
16.
Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice.
Jormsjo S, etal., Am J Pathol. 2002 Sep;161(3):939-45.
17.
Study of the functional share of lysosomal cathepsins by the development of specific inhibitors.
Katunuma N, etal., Adv Enzyme Regul. 1999;39:247-60.
18.
Differential expression of Cathepsin S and X in the spinal cord of a rat neuropathic pain model.
Leichsenring A, etal., BMC Neurosci. 2008 Aug 12;9:80.
19.
The lysosomal cysteine protease, cathepsin S, is increased in Alzheimer's disease and Down syndrome brain. An immunocytochemical study.
Lemere CA, etal., Am J Pathol. 1995 Apr;146(4):848-60.
20.
Baculoviral expression and characterization of rodent cathepsin S.
Mason CS, etal., Protein Expr Purif. 2001 Oct;23(1):45-54.
21.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
22.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
23.
Sequence analysis, tissue distribution, and expression of rat cathepsin S.
Petanceska S and Devi L, J Biol Chem 1992 Dec 25;267(36):26038-43.
24.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
25.
GOA pipeline
RGD automated data pipeline
26.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
27.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
28.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
29.
Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.
Sukhova GK, etal., J Clin Invest. 1998 Aug 1;102(3):576-83.
30.
Functional interface between cathepsins and growth factors in the kidney development.
Vattimo Mde F and Santos OF, Ren Fail. 2005;27(5):615-22.
31.
cDNA microarray analysis of spinal cord injury and regeneration related genes in rat.
Xiao L, etal., Sheng Li Xue Bao. 2005 Dec 25;57(6):705-13.
Ctss Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 185,775,316 - 185,803,440 (+) NCBI GRCr8 mRatBN7.2 2 183,086,437 - 183,114,483 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 183,086,437 - 183,114,483 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 2 190,751,075 - 190,779,335 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 188,546,398 - 188,574,853 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 183,383,602 - 183,411,862 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 197,655,780 - 197,679,768 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 197,655,786 - 197,679,458 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 2 217,144,866 - 217,169,058 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 2 190,425,290 - 190,466,877 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 2 190,385,391 - 190,429,631 (+) NCBI Celera 2 175,621,979 - 175,645,341 (+) NCBI Celera Cytogenetic Map 2 q34 NCBI
CTSS Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 150,730,188 - 150,765,778 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 150,730,079 - 150,765,957 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 150,702,664 - 150,738,254 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 148,969,175 - 149,004,929 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 147,515,623 - 147,551,378 NCBI Celera 1 123,818,402 - 123,853,717 (-) NCBI Celera Cytogenetic Map 1 q21.3 NCBI HuRef 1 122,080,971 - 122,116,053 (-) NCBI HuRef CHM1_1 1 152,098,024 - 152,133,771 (-) NCBI CHM1_1 T2T-CHM13v2.0 1 149,853,594 - 149,889,583 (-) NCBI T2T-CHM13v2.0
Ctss Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 3 95,434,097 - 95,463,716 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 3 95,434,097 - 95,463,714 (+) Ensembl GRCm39 Ensembl GRCm38 3 95,526,786 - 95,556,405 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 3 95,526,786 - 95,556,403 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 3 95,330,708 - 95,360,325 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 3 95,612,248 - 95,641,803 (+) NCBI MGSCv36 mm8 Celera 3 96,957,909 - 96,987,824 (+) NCBI Celera Cytogenetic Map 3 F2.1 NCBI cM Map 3 40.74 NCBI
Ctss Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955413 99,159 - 124,042 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955413 99,279 - 124,793 (+) NCBI ChiLan1.0 ChiLan1.0
CTSS Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 1 99,064,378 - 99,097,165 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 1 98,818,135 - 98,852,978 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 1 126,084,249 - 126,118,221 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 1 129,733,996 - 129,768,318 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 1 129,733,996 - 129,768,318 (-) Ensembl panpan1.1 panPan2
CTSS Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 17 59,893,840 - 59,910,878 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 17 59,893,840 - 59,910,849 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 17 59,339,729 - 59,356,741 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 17 60,909,903 - 60,927,183 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 17 60,909,903 - 60,947,992 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 17 59,739,445 - 59,756,448 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 17 59,823,472 - 59,840,470 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 17 60,551,720 - 60,568,999 (-) NCBI UU_Cfam_GSD_1.0
Ctss
CTSS Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 4 98,417,883 - 98,442,950 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 4 98,415,273 - 98,442,952 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 4 107,665,975 - 107,691,575 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
CTSS Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Vero_WHO_p1.0 NW_023666038 12,512,460 - 12,548,903 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Ctss
.
Predicted Target Of
Count of predictions: 190 Count of miRNA genes: 138 Interacting mature miRNAs: 151 Transcripts: ENSRNOT00000028732 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1578648 Bss11 Bone structure and strength QTL 11 4.7 femur morphology trait (VT:0000559) femoral neck cortical cross-sectional area (CMO:0001702) 2 114837527 211674221 Rat 1358356 Srcrt1 Stress Responsive Cort QTL1 3.66 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 2 161699179 222436696 Rat 1331734 Bp204 Blood pressure QTL 204 3.61192 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 168358098 223265385 Rat 1298074 Bp164 Blood pressure QTL 164 0.003 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 42804607 202447032 Rat 1354648 Bp239 Blood pressure QTL 239 0.001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 66118463 226797303 Rat 1354649 Kidm17 Kidney mass QTL 17 2.9 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 2 81754530 227146641 Rat 10755499 Bp389 Blood pressure QTL 389 2.61 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 2 18960362 228801039 Rat 1298076 Bp166 Blood pressure QTL 166 0.0009 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 136445150 202447032 Rat 152025245 Scl81 Serum cholesterol level QTL 81 3.49 blood cholesterol amount (VT:0000180) 2 122609194 206936711 Rat 70162 Bp63 Blood pressure QTL 63 5.64 arterial blood pressure trait (VT:2000000) blood pressure measurement (CMO:0000003) 2 169745596 214745596 Rat 1554319 Bmd2 Bone mineral density QTL 2 13.4 0.0001 lumbar vertebra area (VT:0010570) lumbar vertebra cross-sectional area (CMO:0001689) 2 114837675 212549332 Rat 12879836 Kidm61 Kidney mass QTL 61 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 2 152413072 185122374 Rat 1581569 Uae32 Urinary albumin excretion QTL 32 0.0001 urine protein amount (VT:0005160) urine albumin excretion rate (CMO:0000757) 2 78665619 219826953 Rat 10043136 Iddm54 Insulin dependent diabetes mellitus QTL 54 3.4 0.0001 blood glucose amount (VT:0000188) age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140) 2 143657411 190602963 Rat 12879837 Am2 Aortic mass QTL 2 0.001 aorta mass (VT:0002845) aorta weight to aorta length to body weight ratio (CMO:0002722) 2 152413072 185122374 Rat 12879838 Cm86 Cardiac mass QTL 86 0.002 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 2 152413072 185122374 Rat 1302793 Bw16 Body weight QTL 16 5 0.0001 body mass (VT:0001259) body weight (CMO:0000012) 2 157142209 202446871 Rat 61467 Bp14 Blood pressure QTL 14 2.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 43154682 202446871 Rat 12879839 Cm85 Cardiac mass QTL 85 0.001 heart mass (VT:0007028) heart wet weight to body weight ratio (CMO:0002408) 2 152413072 185122374 Rat 61469 Bp16 Blood pressure QTL 16 5.64 arterial blood pressure trait (VT:2000000) blood pressure measurement (CMO:0000003) 2 169745596 214745596 Rat 70175 BpQTLCluster3 Blood pressure QTL cluster 3 4.128 arterial blood pressure trait (VT:2000000) absolute change in systolic blood pressure (CMO:0000607) 2 135552573 202446871 Rat 1549833 Bp257 Blood pressure QTL 257 0.003 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 168354880 185122374 Rat 1358900 Bw48 Body weight QTL 48 4.88 body mass (VT:0001259) body weight (CMO:0000012) 2 157142078 211086598 Rat 1359030 Bp277 Blood pressure QTL 277 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 2 114837527 185876470 Rat 1331760 Bp206 Blood pressure QTL 206 3.62454 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 56043031 202447032 Rat 12879840 Bw179 Body weight QTL 179 0.005 body mass (VT:0001259) body weight (CMO:0000012) 2 152413072 185122374 Rat 1581502 Esta3 Estrogen-induced thymic atrophy QTL 3 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 2 136916935 189599348 Rat 9589044 Scfw1 Subcutaneous fat weight QTL 1 5.8 0.001 subcutaneous adipose mass (VT:1000472) abdominal subcutaneous fat pad weight (CMO:0002069) 2 182171407 227171407 Rat 8694435 Bw166 Body weight QTL 166 14.08 0.001 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 2 182171407 227171407 Rat 1359032 Hrtrt18 Heart rate QTL 18 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 2 157142078 192625452 Rat 2301966 Bp322 Blood pressure QTL 322 3.58 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 150540301 202447032 Rat 1298080 Bp163 Blood pressure QTL 163 0.02 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 66118275 202447032 Rat 8662832 Vetf7 Vascular elastic tissue fragility QTL 7 3.5 aorta elastin amount (VT:0003905) aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002) 2 81689826 221035911 Rat 1298085 Bp165 Blood pressure QTL 165 0.0006 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 42804607 202447032 Rat 8694194 Abfw1 Abdominal fat weight QTL 1 11.7 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 2 182171407 227171407 Rat 1359022 Ppulsi1 Prepulse inhibition QTL 1 3.63 prepulse inhibition trait (VT:0003088) acoustic startle response measurement (CMO:0001519) 2 136916935 213594495 Rat 1641891 Alcrsp17 Alcohol response QTL 17 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 2 149559561 249053267 Rat 724534 Uae6 Urinary albumin excretion QTL 6 10 urine albumin amount (VT:0002871) urine albumin level (CMO:0000130) 2 78665619 249053267 Rat 61374 Edpm2 Estrogen-dependent pituitary mass QTL 2 4.42 0.86 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 2 76539322 202447032 Rat 2300189 Bmd48 Bone mineral density QTL 48 5.8 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 2 179335906 224335906 Rat 8662843 Vetf9 Vascular elastic tissue fragility QTL 9 2.05 thoracic aorta molecular composition trait (VT:0010568) aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003) 2 157142078 226277316 Rat 631501 Bp101 Blood pressure QTL 101 2.4 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 150341684 202446871 Rat 2307174 Activ3 Activity QTL 3 4.83 0.000058 locomotor behavior trait (VT:0001392) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 2 168594495 213594495 Rat 1331794 Bp202 Blood pressure QTL 202 3.66819 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 141194931 223265385 Rat 71113 Cari2 Carrageenan-induced inflammation QTL 2 2.7 0.009 hypodermis integrity trait (VT:0010550) inflammatory exudate volume (CMO:0001429) 2 141596551 202447032 Rat 1331805 Cm29 Cardiac mass QTL 29 3.50746 heart mass (VT:0007028) heart wet weight (CMO:0000069) 2 141194931 223265385 Rat 634308 Sach6 Saccharin preference QTL 6 4.9 taste sensitivity trait (VT:0001986) saccharin intake volume to total fluid intake volume ratio (CMO:0001601) 2 112456140 212696837 Rat 1598805 Memor8 Memory QTL 8 3 exploratory behavior trait (VT:0010471) average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674) 2 150341585 189039377 Rat 1358917 Cm42 Cardiac mass QTL 42 2.82 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 2 25413423 203928301 Rat 724568 Uae13 Urinary albumin excretion QTL 13 4.4 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 2 143157029 210020885 Rat 1358913 Cm41 Cardiac mass QTL 41 2.73 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 2 25413423 203928301 Rat 1300165 Rf9 Renal function QTL 9 3.28 kidney glomerulus integrity trait (VT:0010546) index of glomerular damage (CMO:0001135) 2 133914684 202447032 Rat 61401 Niddm2 Non-insulin dependent diabetes mellitus QTL 2 4.54 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 2 144599348 189599348 Rat 631507 Bp105 Blood pressure QTL 105 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 112456140 212696837 Rat 1641925 Alcrsp2 Alcohol response QTL 2 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 2 149559561 221167075 Rat 1354609 Niddm62 Non-insulin dependent diabetes mellitus QTL 62 4.72 0.000006 insulin secretion trait (VT:0003564) plasma insulin level (CMO:0000342) 2 150540301 202447032 Rat 1598833 Bp295 Blood pressure QTL 295 3.5 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 147798556 192798556 Rat 61417 Cia10 Collagen induced arthritis QTL 10 3.4 joint integrity trait (VT:0010548) experimental arthritis severity measurement (CMO:0001459) 2 179946951 224946951 Rat 1354622 Kidm16 Kidney mass QTL 16 3 kidney mass (VT:0002707) left kidney wet weight (CMO:0000083) 2 81754530 222436696 Rat 631266 Bp132 Blood pressure QTL 132 0.0005 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 46123260 202447032 Rat 631522 Bp74 Blood pressure QTL 74 0.05 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 172710921 184114403 Rat 8694383 Bw158 Body weight QTL 158 7.69 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 2 182171407 227171407 Rat 7488927 Bp365 Blood pressure QTL 365 0.008 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 162765032 207765032 Rat 1598838 Bp290 Blood pressure QTL 290 1.9 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 166539266 211539266 Rat 7488925 Bp364 Blood pressure QTL 364 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 160564068 205564068 Rat 2306901 Bp337 Blood pressure QTL 337 0.01 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 164073756 227146641 Rat 1354605 Rf48 Renal function QTL 48 2.9 blood creatinine amount (VT:0005328) plasma creatinine level (CMO:0000537) 2 74786664 206665859 Rat 6903312 Bw112 Body weight QTL 112 3.2 0.0013 body mass (VT:0001259) body weight (CMO:0000012) 2 143657569 184114274 Rat 1354601 Slep1 Serum leptin concentration QTL 1 5.39 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 2 43171017 184114403 Rat 2293084 Iddm26 Insulin dependent diabetes mellitus QTL 26 2.9 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 2 174930955 213594495 Rat
D2Mco48
Rat Assembly Chr Position (strand) Source JBrowse Rnor_5.0 20 34,115,408 - 34,116,469 NCBI Rnor5.0 RGSC_v3.4 20 29,853,888 - 29,855,558 UniSTS RGSC3.4 RGSC_v3.4 2 190,427,909 - 190,428,097 UniSTS RGSC3.4 Celera 8 40,643,459 - 40,644,632 UniSTS Celera 2 175,624,598 - 175,624,786 UniSTS Cytogenetic Map 2 q34 UniSTS
RH128983
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 183,114,193 - 183,114,407 (+) MAPPER mRatBN7.2 Rnor_6.0 2 197,679,479 - 197,679,692 NCBI Rnor6.0 Rnor_5.0 2 217,168,769 - 217,168,982 UniSTS Rnor5.0 RGSC_v3.4 2 190,466,588 - 190,466,801 UniSTS RGSC3.4 Celera 2 175,645,052 - 175,645,265 UniSTS RH 3.4 Map 2 1212.9 UniSTS Cytogenetic Map 2 q34 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000028732 ⟹ ENSRNOP00000028732
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 183,089,198 - 183,114,483 (+) Ensembl Rnor_6.0 Ensembl 2 197,655,786 - 197,679,458 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000102986 ⟹ ENSRNOP00000088061
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 183,089,198 - 183,114,483 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000105420 ⟹ ENSRNOP00000092901
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 183,086,437 - 183,114,483 (+) Ensembl
RefSeq Acc Id:
NM_017320 ⟹ NP_059016
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 185,775,396 - 185,803,440 (+) NCBI mRatBN7.2 2 183,086,437 - 183,114,483 (+) NCBI Rnor_6.0 2 197,655,780 - 197,679,768 (+) NCBI Rnor_5.0 2 217,144,866 - 217,169,058 (+) NCBI RGSC_v3.4 2 190,425,290 - 190,466,877 (+) RGD Celera 2 175,621,979 - 175,645,341 (+) RGD
Sequence:
GGGACTCTCTCATGCCGCCATACGGAGATGGCTGTTTTGGGTGCCCCTGGTGTGCTCTGTGACAATGGAGCAACTGCAGAGAGACCTACCCTGGACCACCACTGGGATCTCTGGAAGAAAACTCGCAT
hide sequence
RefSeq Acc Id:
XM_063282416 ⟹ XP_063138486
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 185,775,316 - 185,803,440 (+) NCBI
RefSeq Acc Id:
NP_059016 ⟸ NM_017320
- Peptide Label:
preproprotein
- UniProtKB:
A0A8I6AES4 (UniProtKB/TrEMBL), A6K2Z7 (UniProtKB/TrEMBL)
- Sequence:
MAVLGAPGVLCDNGATAERPTLDHHWDLWKKTRMRRNTDQNEEDVRRLIWEKNLKFIMLHNLEHSMGMHSYSVGMNHMGDMTPEEVIGYMGSLRIPRPWNRSGTLKSSSNQTLPDSVDWREKGCVTNV
hide sequence
Ensembl Acc Id:
ENSRNOP00000028732 ⟸ ENSRNOT00000028732
Ensembl Acc Id:
ENSRNOP00000088061 ⟸ ENSRNOT00000102986
Ensembl Acc Id:
ENSRNOP00000092901 ⟸ ENSRNOT00000105420
RefSeq Acc Id:
XP_063138486 ⟸ XM_063282416
- Peptide Label:
isoform X1
- UniProtKB:
A6K2Z7 (UniProtKB/TrEMBL)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2004-09-10
Ctss
cathepsin S
Symbol and Name status set to approved
1299863 APPROVED
2002-08-07
Ctss
cathepsin S
Symbol and Name status set to provisional
70820 PROVISIONAL
Note Type
Note
Reference
gene_expression
enriched in brain, ovary, and uterus; present in thyroglobulin containing follicular cells
727522
gene_protein
retains proteolytic activity at neutral pH
727522
gene_regulation
induced by thyroid-stimulating hormone
727522
