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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | peripheral nervous system disease | | ISO | RGD:734329 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21228734 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | peripheral nervous system disease | | ISO | RGD:734329 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21228734 | |
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# | Reference Title | Reference Citation |
1. | Cytoplasmic dynein. | Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169. |
2. | Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon. | Fejtova A, etal., J Cell Biol. 2009 Apr 20;185(2):341-55. doi: 10.1083/jcb.200807155. |
3. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
4. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
5. | A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. | Ligon LA, etal., J Biol Chem. 2004 Apr 30;279(18):19201-8. Epub 2004 Feb 24. |
6. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
7. | Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function. | Paschal BM, etal., J Cell Biol 1992 Sep;118(5):1133-43. |
8. | Identification and developmental regulation of a neuron-specific subunit of cytoplasmic dynein. | Pfister KK, etal., Mol Biol Cell. 1996 Feb;7(2):331-43. |
9. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
10. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
11. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
12. | Tentative Sequence Identification Numbers | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
PMID:11148215 | PMID:15121898 | PMID:15748847 | PMID:16051887 | PMID:16449194 | PMID:19229290 | PMID:20682791 | PMID:21911489 | PMID:22871113 | PMID:23577064 | PMID:23704327 | PMID:24561039 |
PMID:25540360 |
Dync1i1 (Rattus norvegicus - Norway rat) |
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DYNC1I1 (Homo sapiens - human) |
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Dync1i1 (Mus musculus - house mouse) |
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Dync1i1 (Chinchilla lanigera - long-tailed chinchilla) |
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DYNC1I1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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DYNC1I1 (Canis lupus familiaris - dog) |
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Dync1i1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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DYNC1I1 (Sus scrofa - pig) |
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DYNC1I1 (Chlorocebus sabaeus - green monkey) |
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Dync1i1 (Heterocephalus glaber - naked mole-rat) |
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The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 8 | 58 | 1 | ||||||||||
Low | 2 | 6 | 19 | 12 | 9 | 12 | 7 | 8 | 14 | 16 | 40 | 2 | 7 |
Below cutoff | 1 | 32 | 24 | 23 | 8 | 23 | 1 | 3 | 2 | 12 | 7 | 1 |
RefSeq Transcripts | NM_019234 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006236026 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017592507 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017592508 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017592509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017592510 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC091353 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC095999 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AC099174 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473959 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JACYVU010000141 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
KU343212 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
KU343213 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
KU343214 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
KU343215 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
X66845 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000013184 ⟹ ENSRNOP00000013184 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000100335 ⟹ ENSRNOP00000094274 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000106012 ⟹ ENSRNOP00000080715 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000109704 ⟹ ENSRNOP00000092857 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000117171 ⟹ ENSRNOP00000085770 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_019234 ⟹ NP_062107 | ||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006236026 ⟹ XP_006236088 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017592507 ⟹ XP_017447996 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017592509 ⟹ XP_017447998 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_062107 | (Get FASTA) | NCBI Sequence Viewer |
XP_006236088 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017447996 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017447998 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | ANG60407 | (Get FASTA) | NCBI Sequence Viewer |
ANG60408 | (Get FASTA) | NCBI Sequence Viewer | |
ANG60409 | (Get FASTA) | NCBI Sequence Viewer | |
ANG60410 | (Get FASTA) | NCBI Sequence Viewer | |
CAA47321 | (Get FASTA) | NCBI Sequence Viewer | |
EDM15026 | (Get FASTA) | NCBI Sequence Viewer | |
EDM15027 | (Get FASTA) | NCBI Sequence Viewer | |
EDM15028 | (Get FASTA) | NCBI Sequence Viewer | |
Q63100 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_062107 ⟸ NM_019234 |
- Sequence: |
RefSeq Acc Id: | XP_006236088 ⟸ XM_006236026 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A173DW29 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017447996 ⟸ XM_017592507 |
- Peptide Label: | isoform X2 |
- Sequence: |
RefSeq Acc Id: | XP_017447998 ⟸ XM_017592509 |
- Peptide Label: | isoform X3 |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000013184 ⟸ ENSRNOT00000013184 |
RefSeq Acc Id: | ENSRNOP00000085770 ⟸ ENSRNOT00000117171 |
RefSeq Acc Id: | ENSRNOP00000092857 ⟸ ENSRNOT00000109704 |
RefSeq Acc Id: | ENSRNOP00000094274 ⟸ ENSRNOT00000100335 |
RefSeq Acc Id: | ENSRNOP00000080715 ⟸ ENSRNOT00000106012 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q63100-F1-model_v2 | AlphaFold | Q63100 | 1-643 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13692862 | ||||||||
Promoter ID: | EPDNEW_R3386 | ||||||||
Type: | initiation region | ||||||||
Name: | Dync1i1_1 | ||||||||
Description: | dynein cytoplasmic 1 intermediate chain 1 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:2512 | AgrOrtholog |
BioCyc Gene | G2FUF-45702 | BioCyc |
Ensembl Genes | ENSRNOG00000009700 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000013184 | ENTREZGENE |
ENSRNOP00000013184.5 | UniProtKB/TrEMBL | |
ENSRNOP00000080715.1 | UniProtKB/TrEMBL | |
ENSRNOP00000085770 | ENTREZGENE | |
ENSRNOP00000085770.1 | UniProtKB/TrEMBL | |
ENSRNOP00000092857 | ENTREZGENE | |
ENSRNOP00000092857.1 | UniProtKB/TrEMBL | |
ENSRNOP00000094274.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000013184 | ENTREZGENE |
ENSRNOT00000013184.5 | UniProtKB/TrEMBL | |
ENSRNOT00000100335.1 | UniProtKB/TrEMBL | |
ENSRNOT00000106012.1 | UniProtKB/TrEMBL | |
ENSRNOT00000109704 | ENTREZGENE | |
ENSRNOT00000109704.1 | UniProtKB/TrEMBL | |
ENSRNOT00000117171 | ENTREZGENE | |
ENSRNOT00000117171.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.130.10.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | DYNC1I1/DYNC1I2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
WD40/YVTN_repeat-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
WD40_repeat | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
WD40_repeat_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:29564 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
NCBI Gene | 29564 | ENTREZGENE |
Pfam | Dynein_IC2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
WD40 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Dync1i1 | PhenoGen |
PROSITE | WD_REPEATS_REGION | UniProtKB/Swiss-Prot |
SMART | WD40 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF50978 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TIGR | TC206306 | |
UniProt | A0A173DW29 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6A2D5_RAT | UniProtKB/TrEMBL | |
A0A8I6AHE2_RAT | UniProtKB/TrEMBL | |
A0A8I6AKL2_RAT | UniProtKB/TrEMBL | |
A0A8I6G4X7_RAT | UniProtKB/TrEMBL | |
DC1I1_RAT | UniProtKB/Swiss-Prot | |
G3V792_RAT | UniProtKB/TrEMBL | |
Q63100 | ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2006-03-30 | Dync1i1 | dynein cytoplasmic 1 intermediate chain 1 | Dncic1 | dynein, cytoplasmic, intermediate chain 1 | Symbol and Name updated | 1299863 | APPROVED |
2002-11-06 | Dncic1 | dynein, cytoplasmic, intermediate chain 1 | Dnci1 | Symbol and Name updated | 625702 | APPROVED | |
2002-06-10 | Dnci1 | dynein, cytoplasmic, intermediate chain 1 | Name updated | 70584 | APPROVED | ||
2001-12-06 | Dnci 1 | dynein, cytoplasmic, intermediate chain 1 | Symbol updated to reflect Human and Mouse nomenclature | 69665 | APPROVED |
Note Type | Note | Reference |
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gene_physical_interaction | binds alpha tubulin | 69826 |
gene_process | may mediate the interaction of cytoplasmic dynein with membranous organelles and kinetochores | 69826 |
gene_process | may be involved in subcellular targeting | 69826 |