Dync1i1 (dynein cytoplasmic 1 intermediate chain 1) - Rat Genome Database

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Gene: Dync1i1 (dynein cytoplasmic 1 intermediate chain 1) Rattus norvegicus
Analyze
Symbol: Dync1i1
Name: dynein cytoplasmic 1 intermediate chain 1
RGD ID: 2512
Description: Enables microtubule binding activity and microtubule motor activity. Involved in brain development and vesicle transport along microtubule. Located in axon cytoplasm and perinuclear region of cytoplasm. Part of cytoplasmic dynein complex. Colocalizes with piccolo-bassoon transport vesicle. Orthologous to human DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1); PARTICIPATES IN mitochondria transport pathway; phagocytosis pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytoplasmic dynein 1 intermediate chain 1; cytoplasmic dynein intermediate chain 1; DH IC-1; Dnci 1; Dnci1; Dncic1; dynein cytoplasmic 1 intermediate chain 1A; dynein cytoplasmic 1 intermediate chain 1B; dynein cytoplasmic 1 intermediate chain 1C; dynein cytoplasmic 1 intermediate chain 1D; dynein intermediate chain 1, cytosolic; dynein, cytoplasmic, intermediate chain 1; IC74-1A; IC74-1B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2433,852,597 - 34,166,159 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)Ensembl
Rnor_6.0430,807,755 - 31,121,097 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl430,807,879 - 31,121,090 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0430,714,935 - 31,028,010 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4430,496,410 - 30,809,622 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1430,547,347 - 30,880,140 (+)NCBI
Celera429,377,971 - 29,690,505 (+)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cytoplasmic dynein. Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169.
2. Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon. Fejtova A, etal., J Cell Biol. 2009 Apr 20;185(2):341-55. doi: 10.1083/jcb.200807155.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. Ligon LA, etal., J Biol Chem. 2004 Apr 30;279(18):19201-8. Epub 2004 Feb 24.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function. Paschal BM, etal., J Cell Biol 1992 Sep;118(5):1133-43.
8. Identification and developmental regulation of a neuron-specific subunit of cytoplasmic dynein. Pfister KK, etal., Mol Biol Cell. 1996 Feb;7(2):331-43.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11148215   PMID:15121898   PMID:15748847   PMID:16051887   PMID:16449194   PMID:19229290   PMID:20682791   PMID:21911489   PMID:22871113   PMID:23577064   PMID:23704327   PMID:24561039  
PMID:25540360  


Genomics

Comparative Map Data
Dync1i1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2433,852,597 - 34,166,159 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)Ensembl
Rnor_6.0430,807,755 - 31,121,097 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl430,807,879 - 31,121,090 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0430,714,935 - 31,028,010 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4430,496,410 - 30,809,622 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1430,547,347 - 30,880,140 (+)NCBI
Celera429,377,971 - 29,690,505 (+)NCBICelera
Cytogenetic Map4q13NCBI
DYNC1I1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38795,772,554 - 96,110,322 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl795,772,506 - 96,110,322 (+)EnsemblGRCh38hg38GRCh38
GRCh37795,401,866 - 95,739,634 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36795,239,838 - 95,565,660 (+)NCBINCBI36hg18NCBI36
Build 34795,046,552 - 95,372,375NCBI
Celera790,101,694 - 90,427,608 (+)NCBI
Cytogenetic Map7q21.3NCBI
HuRef790,008,652 - 90,347,456 (+)NCBIHuRef
CHM1_1795,331,673 - 95,669,665 (+)NCBICHM1_1
T2T-CHM13v2.0797,008,421 - 97,346,216 (+)NCBI
CRA_TCAGchr7v2794,730,870 - 95,068,701 (+)NCBI
Dync1i1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3965,725,593 - 6,028,039 (+)NCBIGRCm39mm39
GRCm39 Ensembl65,725,639 - 6,028,039 (+)Ensembl
GRCm3865,725,600 - 6,028,039 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl65,725,639 - 6,028,039 (+)EnsemblGRCm38mm10GRCm38
MGSCv3765,675,639 - 5,978,039 (+)NCBIGRCm37mm9NCBIm37
MGSCv3665,675,808 - 5,978,039 (+)NCBImm8
Celera65,874,647 - 6,178,900 (+)NCBICelera
Cytogenetic Map6A1NCBI
cM Map62.26NCBI
Dync1i1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543212,353,993 - 12,658,157 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543212,383,582 - 12,657,491 (+)NCBIChiLan1.0ChiLan1.0
DYNC1I1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17101,311,839 - 101,637,149 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7101,344,053 - 101,648,607 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0787,724,604 - 88,050,624 (+)NCBIMhudiblu_PPA_v0panPan3
DYNC1I1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11420,967,936 - 21,279,044 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1420,968,011 - 21,278,363 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1420,526,736 - 20,837,733 (+)NCBI
ROS_Cfam_1.01420,790,257 - 21,100,686 (+)NCBI
ROS_Cfam_1.0 Ensembl1420,790,150 - 21,100,690 (+)Ensembl
UMICH_Zoey_3.11420,935,563 - 21,246,926 (+)NCBI
UNSW_CanFamBas_1.01420,669,529 - 20,980,440 (+)NCBI
UU_Cfam_GSD_1.01420,927,298 - 21,238,416 (+)NCBI
Dync1i1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511834,336,964 - 34,630,858 (+)NCBI
SpeTri2.0NW_0049365854,232,428 - 4,496,878 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNC1I1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl975,414,755 - 75,760,519 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1975,414,663 - 75,760,527 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2983,031,974 - 83,173,009 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYNC1I1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12152,950,983 - 53,271,113 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2152,950,874 - 53,271,130 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604251,081,941 - 51,402,088 (+)NCBIVero_WHO_p1.0
Dync1i1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248132,490,706 - 2,825,412 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248132,490,745 - 2,826,230 (+)NCBIHetGla_female_1.0hetGla2


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42133334344463908Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)42271068534430484Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43258419952754138Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:286
Count of miRNA genes:175
Interacting mature miRNAs:202
Transcripts:ENSRNOT00000013184
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 58 1
Low 2 6 19 12 9 12 7 8 14 16 40 2 7
Below cutoff 1 32 24 23 8 23 1 3 2 12 7 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC091353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC095999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC099174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU343212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU343213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU343214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU343215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000013184   ⟹   ENSRNOP00000013184
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)Ensembl
Rnor_6.0 Ensembl430,807,879 - 31,121,090 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100335   ⟹   ENSRNOP00000094274
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl433,895,878 - 34,166,149 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106012   ⟹   ENSRNOP00000080715
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl434,141,856 - 34,166,149 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109704   ⟹   ENSRNOP00000092857
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117171   ⟹   ENSRNOP00000085770
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)Ensembl
RefSeq Acc Id: NM_019234   ⟹   NP_062107
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2433,852,927 - 34,166,150 (+)NCBI
Rnor_6.0430,807,879 - 31,121,091 (+)NCBI
Rnor_5.0430,714,935 - 31,028,010 (+)NCBI
RGSC_v3.4430,496,410 - 30,809,622 (+)RGD
Celera429,377,971 - 29,690,505 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236026   ⟹   XP_006236088
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2433,852,603 - 34,166,159 (+)NCBI
Rnor_6.0430,807,759 - 31,121,097 (+)NCBI
Rnor_5.0430,714,935 - 31,028,010 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592507   ⟹   XP_017447996
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2433,852,597 - 34,166,159 (+)NCBI
Rnor_6.0430,807,755 - 31,121,097 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592509   ⟹   XP_017447998
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2433,852,602 - 34,166,159 (+)NCBI
Rnor_6.0430,807,759 - 31,121,097 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_062107   ⟸   NM_019234
- Sequence:
RefSeq Acc Id: XP_006236088   ⟸   XM_006236026
- Peptide Label: isoform X1
- UniProtKB: A0A173DW29 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447996   ⟸   XM_017592507
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017447998   ⟸   XM_017592509
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000013184   ⟸   ENSRNOT00000013184
RefSeq Acc Id: ENSRNOP00000085770   ⟸   ENSRNOT00000117171
RefSeq Acc Id: ENSRNOP00000092857   ⟸   ENSRNOT00000109704
RefSeq Acc Id: ENSRNOP00000094274   ⟸   ENSRNOT00000100335
RefSeq Acc Id: ENSRNOP00000080715   ⟸   ENSRNOT00000106012

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63100-F1-model_v2 AlphaFold Q63100 1-643 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692862
Promoter ID:EPDNEW_R3386
Type:initiation region
Name:Dync1i1_1
Description:dynein cytoplasmic 1 intermediate chain 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0430,807,912 - 30,807,972EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2512 AgrOrtholog
BioCyc Gene G2FUF-45702 BioCyc
Ensembl Genes ENSRNOG00000009700 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000013184 ENTREZGENE
  ENSRNOP00000013184.5 UniProtKB/TrEMBL
  ENSRNOP00000080715.1 UniProtKB/TrEMBL
  ENSRNOP00000085770 ENTREZGENE
  ENSRNOP00000085770.1 UniProtKB/TrEMBL
  ENSRNOP00000092857 ENTREZGENE
  ENSRNOP00000092857.1 UniProtKB/TrEMBL
  ENSRNOP00000094274.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013184 ENTREZGENE
  ENSRNOT00000013184.5 UniProtKB/TrEMBL
  ENSRNOT00000100335.1 UniProtKB/TrEMBL
  ENSRNOT00000106012.1 UniProtKB/TrEMBL
  ENSRNOT00000109704 ENTREZGENE
  ENSRNOT00000109704.1 UniProtKB/TrEMBL
  ENSRNOT00000117171 ENTREZGENE
  ENSRNOT00000117171.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DYNC1I1/DYNC1I2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29564 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 29564 ENTREZGENE
Pfam Dynein_IC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dync1i1 PhenoGen
PROSITE WD_REPEATS_REGION UniProtKB/Swiss-Prot
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC206306
UniProt A0A173DW29 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2D5_RAT UniProtKB/TrEMBL
  A0A8I6AHE2_RAT UniProtKB/TrEMBL
  A0A8I6AKL2_RAT UniProtKB/TrEMBL
  A0A8I6G4X7_RAT UniProtKB/TrEMBL
  DC1I1_RAT UniProtKB/Swiss-Prot
  G3V792_RAT UniProtKB/TrEMBL
  Q63100 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Dync1i1  dynein cytoplasmic 1 intermediate chain 1  Dncic1  dynein, cytoplasmic, intermediate chain 1  Symbol and Name updated 1299863 APPROVED
2002-11-06 Dncic1  dynein, cytoplasmic, intermediate chain 1  Dnci1    Symbol and Name updated 625702 APPROVED
2002-06-10 Dnci1  dynein, cytoplasmic, intermediate chain 1      Name updated 70584 APPROVED
2001-12-06 Dnci 1  dynein, cytoplasmic, intermediate chain 1      Symbol updated to reflect Human and Mouse nomenclature 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds alpha tubulin 69826
gene_process may mediate the interaction of cytoplasmic dynein with membranous organelles and kinetochores 69826
gene_process may be involved in subcellular targeting 69826