Dnajc3 (DnaJ heat shock protein family (Hsp40) member C3) - Rat Genome Database

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Gene: Dnajc3 (DnaJ heat shock protein family (Hsp40) member C3) Rattus norvegicus
Analyze
Symbol: Dnajc3
Name: DnaJ heat shock protein family (Hsp40) member C3
RGD ID: 708518
Description: Predicted to enable several functions, including misfolded protein binding activity; protein kinase inhibitor activity; and protein-folding chaperone binding activity. Predicted to be involved in several processes, including cellular response to cold; protein folding in endoplasmic reticulum; and regulation of translational initiation. Located in smooth endoplasmic reticulum. Orthologous to human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; influenza A pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DnaJ (Hsp40) homolog, subfamily C, member 3; dnaJ homolog subfamily C member 3; interferon-induced, double-stranded RNA-activated protein kinase inhibitor; LOC63880; protein kinase inhibitor of 58 kDa; protein kinase inhibitor p58
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815102,432,667 - 102,475,643 (+)NCBIGRCr8
mRatBN7.21596,025,605 - 96,068,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1596,025,624 - 96,065,181 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1599,935,638 - 99,977,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015101,066,102 - 101,108,631 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01597,995,046 - 98,037,458 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015104,186,918 - 104,226,236 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15104,186,792 - 104,226,329 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015107,610,329 - 107,649,355 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415103,881,634 - 103,921,295 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115103,897,413 - 103,937,075 (+)NCBI
Celera1594,875,150 - 94,914,827 (+)NCBICelera
Cytogenetic Map15q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP,ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
atrazine  (EXP)
benzbromarone  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbaryl  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (ISO)
clobetasol  (ISO)
clofibrate  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (EXP)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDE  (ISO)
DDT  (EXP)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
ethanol  (ISO)
fenofibrate  (ISO)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glucose  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hydralazine  (ISO)
hydrazine  (ISO)
hydrogen cyanide  (ISO)
ionomycin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
L-serine  (ISO)
lead(0)  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methidathion  (ISO)
methylparaben  (ISO)
motexafin gadolinium  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (ISO)
Nonidet P-40  (ISO)
omeprazole  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phlorizin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP,ISO)
potassium cyanide  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
resveratrol  (ISO)
retinyl acetate  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
SCH 23390  (EXP)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
tunicamycin  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zinc acetate  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. An interaction map of endoplasmic reticulum chaperones and foldases. Jansen G, etal., Mol Cell Proteomics. 2012 Sep;11(9):710-23. doi: 10.1074/mcp.M111.016550. Epub 2012 Jun 4.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. Yan W, etal., Proc Natl Acad Sci U S A 2002 Dec 10;99(25):15920-5. Epub 2002 Nov 22.
Additional References at PubMed
PMID:8666242   PMID:15489334   PMID:16923392   PMID:18923430   PMID:19199708   PMID:19946888   PMID:21245960   PMID:22064321   PMID:23376485   PMID:23395000   PMID:24769233   PMID:25329545  


Genomics

Comparative Map Data
Dnajc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815102,432,667 - 102,475,643 (+)NCBIGRCr8
mRatBN7.21596,025,605 - 96,068,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1596,025,624 - 96,065,181 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1599,935,638 - 99,977,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015101,066,102 - 101,108,631 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01597,995,046 - 98,037,458 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015104,186,918 - 104,226,236 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15104,186,792 - 104,226,329 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015107,610,329 - 107,649,355 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415103,881,634 - 103,921,295 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115103,897,413 - 103,937,075 (+)NCBI
Celera1594,875,150 - 94,914,827 (+)NCBICelera
Cytogenetic Map15q24NCBI
DNAJC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381395,677,139 - 95,794,988 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1395,677,139 - 95,794,988 (+)EnsemblGRCh38hg38GRCh38
GRCh371396,329,393 - 96,447,242 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361395,127,484 - 95,241,285 (+)NCBINCBI36Build 36hg18NCBI36
Build 341395,127,483 - 95,241,285NCBI
Celera1377,177,188 - 77,295,039 (+)NCBICelera
Cytogenetic Map13q32.1NCBI
HuRef1376,927,193 - 77,044,763 (+)NCBIHuRef
CHM1_11396,299,542 - 96,417,377 (+)NCBICHM1_1
T2T-CHM13v2.01394,881,700 - 94,999,557 (+)NCBIT2T-CHM13v2.0
Dnajc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914119,175,371 - 119,219,114 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14119,175,388 - 119,219,109 (+)EnsemblGRCm39 Ensembl
GRCm3814118,937,932 - 118,981,702 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14118,937,976 - 118,981,697 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714119,337,154 - 119,380,924 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614119,337,209 - 119,379,121 (+)NCBIMGSCv36mm8
Celera14117,490,628 - 117,537,345 (+)NCBICelera
Cytogenetic Map14E4NCBI
cM Map1462.6NCBI
Dnajc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540414,360,832 - 14,412,533 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540414,361,540 - 14,412,533 (-)NCBIChiLan1.0ChiLan1.0
DNAJC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21497,199,547 - 97,319,864 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11395,877,932 - 95,988,726 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01376,853,053 - 76,963,530 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11395,975,607 - 96,114,256 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1396,033,605 - 96,114,165 (+)Ensemblpanpan1.1panPan2
DNAJC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12246,323,263 - 46,402,240 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2246,307,905 - 46,398,625 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2246,093,175 - 46,185,499 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02246,737,351 - 46,829,808 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2246,736,369 - 46,844,494 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12246,400,716 - 46,493,029 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02246,433,934 - 46,526,175 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02246,439,531 - 46,531,587 (+)NCBIUU_Cfam_GSD_1.0
Dnajc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945181,825,991 - 181,896,607 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647214,055,532 - 14,126,211 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647214,055,548 - 14,126,173 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1165,230,162 - 65,303,834 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11165,230,145 - 65,299,084 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21172,092,332 - 72,161,773 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1374,474,643 - 74,582,942 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl374,474,548 - 74,579,048 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604630,900,130 - 31,009,831 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnajc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248792,369,237 - 2,434,433 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248792,369,332 - 2,434,433 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dnajc3
160 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:149
Count of miRNA genes:113
Interacting mature miRNAs:119
Transcripts:ENSRNOT00000014182
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)158226252098288169Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)158226252098288169Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat

Markers in Region
S100a10  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21596,029,801 - 96,030,319 (+)MAPPERmRatBN7.2
Rnor_6.015104,190,990 - 104,191,507NCBIRnor6.0
Rnor_5.015107,614,401 - 107,614,918UniSTSRnor5.0
RGSC_v3.415103,885,706 - 103,886,223UniSTSRGSC3.4
Celera1594,879,221 - 94,879,738UniSTS
Cytogenetic Map15q24UniSTS
Cytogenetic Map2q31-q34UniSTS
RH128467  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22179,229,330 - 179,229,523 (+)MAPPERmRatBN7.2
mRatBN7.21596,029,873 - 96,030,066 (+)MAPPERmRatBN7.2
Rnor_6.015104,191,062 - 104,191,254NCBIRnor6.0
Rnor_6.02193,900,908 - 193,901,100NCBIRnor6.0
Rnor_5.015107,614,473 - 107,614,665UniSTSRnor5.0
Rnor_5.02210,966,438 - 210,966,630UniSTSRnor5.0
RGSC_v3.42186,653,993 - 186,654,185UniSTSRGSC3.4
RGSC_v3.415103,885,778 - 103,885,970UniSTSRGSC3.4
Celera1594,879,293 - 94,879,485UniSTS
Celera2171,057,250 - 171,057,442UniSTS
Cytogenetic Map2q31-q34UniSTS
Cytogenetic Map15q24UniSTS
RH124908  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21596,029,917 - 96,030,073 (+)MAPPERmRatBN7.2
Rnor_6.015104,191,106 - 104,191,261NCBIRnor6.0
Rnor_5.015107,614,517 - 107,614,672UniSTSRnor5.0
RGSC_v3.415103,885,822 - 103,885,977UniSTSRGSC3.4
Celera1594,879,337 - 94,879,492UniSTS
Cytogenetic Map15q24UniSTS
RH125510  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21596,029,919 - 96,030,073 (+)MAPPERmRatBN7.2
Rnor_6.015104,191,108 - 104,191,261NCBIRnor6.0
Rnor_5.015107,614,519 - 107,614,672UniSTSRnor5.0
RGSC_v3.415103,885,824 - 103,885,977UniSTSRGSC3.4
Celera1594,879,339 - 94,879,492UniSTS
Cytogenetic Map15q24UniSTS
S100a10  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21596,029,897 - 96,030,246 (+)MAPPERmRatBN7.2
Rnor_6.015104,191,086 - 104,191,434NCBIRnor6.0
Rnor_5.015107,614,497 - 107,614,845UniSTSRnor5.0
RGSC_v3.415103,885,802 - 103,886,150UniSTSRGSC3.4
Celera1594,879,317 - 94,879,665UniSTS
Cytogenetic Map2q31-q34UniSTS
Cytogenetic Map15q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000014182   ⟹   ENSRNOP00000014182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1596,025,624 - 96,065,181 (+)Ensembl
Rnor_6.0 Ensembl15104,186,792 - 104,226,329 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093411   ⟹   ENSRNOP00000076327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1596,038,395 - 96,065,181 (+)Ensembl
Rnor_6.0 Ensembl15104,220,316 - 104,223,548 (+)Ensembl
RefSeq Acc Id: NM_022232   ⟹   NP_071568
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,432,667 - 102,475,643 (+)NCBI
mRatBN7.21596,025,605 - 96,068,585 (+)NCBI
Rnor_6.015104,186,918 - 104,226,236 (+)NCBI
Rnor_5.015107,610,329 - 107,649,355 (+)NCBI
RGSC_v3.415103,881,634 - 103,921,295 (+)RGD
Celera1594,875,150 - 94,914,827 (+)RGD
Sequence:
RefSeq Acc Id: NP_071568   ⟸   NM_022232
- Peptide Label: precursor
- UniProtKB: Q9R0T3 (UniProtKB/Swiss-Prot),   Q6P7A0 (UniProtKB/Swiss-Prot),   A0A1W2Q6P6 (UniProtKB/TrEMBL),   A6HUH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014182   ⟸   ENSRNOT00000014182
RefSeq Acc Id: ENSRNOP00000076327   ⟸   ENSRNOT00000093411
Protein Domains
J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9R0T3-F1-model_v2 AlphaFold Q9R0T3 1-504 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699876
Promoter ID:EPDNEW_R10399
Type:initiation region
Name:Dnajc3_1
Description:DnaJ heat shock protein family member C3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.015104,186,804 - 104,186,864EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708518 AgrOrtholog
BioCyc Gene G2FUF-12431 BioCyc
Ensembl Genes ENSRNOG00000010352 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055011941 UniProtKB/Swiss-Prot
  ENSRNOG00060009172 UniProtKB/Swiss-Prot
  ENSRNOG00065007879 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014182.6 UniProtKB/Swiss-Prot
  ENSRNOT00000093411.2 UniProtKB/TrEMBL
  ENSRNOT00055020311 UniProtKB/Swiss-Prot
  ENSRNOT00060015454 UniProtKB/Swiss-Prot
  ENSRNOT00065012379 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5621087 IMAGE-MGC_LOAD
InterPro DnaJ_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  J_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:63880 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72454 IMAGE-MGC_LOAD
NCBI Gene 63880 ENTREZGENE
PANTHER DNAJ HOMOLOG SUBFAMILY C MEMBER 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LD25575P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DnaJ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnajc3 PhenoGen
PRINTS JDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DNAJ_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010352 RatGTEx
  ENSRNOG00055011941 RatGTEx
  ENSRNOG00060009172 RatGTEx
  ENSRNOG00065007879 RatGTEx
SMART DnaJ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46565 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1W2Q6P6 ENTREZGENE, UniProtKB/TrEMBL
  A6HUH2 ENTREZGENE, UniProtKB/TrEMBL
  A6HUH3_RAT UniProtKB/TrEMBL
  DNJC3_RAT UniProtKB/Swiss-Prot
  Q6P7A0 ENTREZGENE
  Q9R0T3 ENTREZGENE
UniProt Secondary Q6P7A0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Dnajc3  DnaJ heat shock protein family (Hsp40) member C3  Dnajc3  DnaJ (Hsp40) homolog, subfamily C, member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-27     Dnajc3  DnaJ (Hsp40) homolog, subfamily C, member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dnajc3  DnaJ (Hsp40) homolog, subfamily C, member 3    protein kinase inhibitor p58  Name updated 1299863 APPROVED
2004-09-10 Dnajc3  protein kinase inhibitor p58  LOC63880    Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference