Gene: Ldhb (lactate dehydrogenase B) Rattus norvegicus
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Symbol: Ldhb
Name: lactate dehydrogenase B
Description: ENCODES a protein that exhibits identical protein binding; kinase binding; L-lactate dehydrogenase activity; INVOLVED IN lactate metabolic process; NAD metabolic process; PARTICIPATES IN cysteine and methionine metabolic pathway; gluconeogenesis pathway; glycolysis pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); Breast Neoplasms (ortholog); ductal carcinoma in situ (ortholog); FOUND IN cytosol (ortholog); membrane raft (ortholog); INTERACTS WITH (+)-alpha-tocopherol; 17alpha-ethynylestradiol; 17beta-estradiol
AGR Description: Exhibits several functions, including L-lactate dehydrogenase activity, NAD binding activity, and identical protein binding activity; involved in NAD metabolic process and lactate metabolic process; predicted to localize to the cytosol and membrane raft; orthologous to human LDHB (lactate dehydrogenase B).
Merged Description: Exhibits several functions, including L-lactate dehydrogenase activity, NAD binding activity, and identical protein binding activity; involved in NAD metabolic process and lactate metabolic process; predicted to localize to the cytosol and membrane raft; orthologous to human LDHB (lactate dehydrogenase B); PARTICIPATES IN cysteine and methionine metabolic pathway; gluconeogenesis pathway; glycolysis pathway; INTERACTS WITH (+)-alpha-tocopherol; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: L-lactate dehydrogenase B; L-lactate dehydrogenase B chain; Lactate dehydrogenease B; LDH heart subunit; LDH-B; LDH-H; Ldh2
Orthologs:
Homo sapiens (human) : LDHB (lactate dehydrogenase B)  HGNC  Alliance
Mus musculus (house mouse) : Ldhb (lactate dehydrogenase B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ldhb (lactate dehydrogenase B)
Pan paniscus (bonobo/pygmy chimpanzee) : LDHB (lactate dehydrogenase B)
Canis lupus familiaris (dog) : LDHB (lactate dehydrogenase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ldhb (lactate dehydrogenase B)
Sus scrofa (pig) : LDHB (lactate dehydrogenase B)
more info ...
Related Pseudogenes: LOC367882  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04176,701,980 - 176,719,999 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04240,918,027 - 240,936,014 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44180,061,567 - 180,079,473 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14180,306,690 - 180,322,406 (-)NCBI
Celera4163,963,498 - 163,981,517 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

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Nomenclature History
 
More on Ldhb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2997
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.