Gene: Tek (TEK receptor tyrosine kinase) Rattus norvegicus
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Symbol: Tek
Name: TEK receptor tyrosine kinase
Description: ENCODES a protein that exhibits growth factor binding; protein tyrosine kinase activity (ortholog); signaling receptor activity (ortholog); INVOLVED IN endochondral ossification; glomerulus vasculature development; positive regulation of angiogenesis; PARTICIPATES IN angiopoietin signaling pathway; rheumatoid arthritis pathway; ASSOCIATED WITH acute kidney tubular necrosis; brain ischemia; gastric ulcer; FOUND IN actin filament (ortholog); apical plasma membrane (ortholog); basal plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: angiopoietin-1 receptor; endothelial-specific receptor tyrosine kinase; TEK tyrosine kinase, endothelial; Tie-2; Tie2; tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2
Orthologs:
Homo sapiens (human) : TEK (TEK receptor tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Tek (TEK receptor tyrosine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tek (TEK receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : TEK (TEK receptor tyrosine kinase)
Canis lupus familiaris (dog) : TEK (TEK receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tek (TEK receptor tyrosine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05113,725,717 - 113,852,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05117,672,484 - 117,799,345 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45115,047,195 - 115,196,172 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15115,171,316 - 115,174,864 (+)NCBI
Celera5108,234,353 - 108,354,536 (+)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tek
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620980
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-01-08
Status: ACTIVE