TEK (TEK receptor tyrosine kinase) - Rat Genome Database

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Pathways
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Gene: TEK (TEK receptor tyrosine kinase) Canis lupus familiaris
Analyze
Symbol: TEK
Name: TEK receptor tyrosine kinase
RGD ID: 12184941
Description: ENCODES a protein that exhibits growth factor binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); cell-cell adhesion (ortholog); cell-matrix adhesion (ortholog); PARTICIPATES IN angiopoietin signaling pathway; ASSOCIATED WITH acute kidney tubular necrosis (ortholog); acute myeloid leukemia (ortholog); angiosarcoma (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: angiopoietin-1 receptor; growth factor receptor Tie2/Tek; TEK tyrosine kinase, endothelial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11145,278,375 - 45,377,300 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1145,278,891 - 45,409,093 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1143,955,919 - 44,054,831 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01146,225,355 - 46,324,241 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1146,225,693 - 46,324,239 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11144,881,654 - 44,980,440 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01144,771,574 - 44,870,410 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01145,518,478 - 45,616,970 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IEA,ISO)
cell differentiation  (IEA)
cell surface receptor protein tyrosine kinase signaling pathway  (IEA)
cell-cell adhesion  (ISO)
cell-matrix adhesion  (ISO)
circulatory system development  (IEA)
endochondral ossification  (ISO)
endothelial cell proliferation  (IEA)
glomerulus vasculature development  (ISO)
heart development  (ISO)
heart trabecula formation  (ISO)
hemopoiesis  (ISO)
negative regulation of angiogenesis  (IEA)
negative regulation of apoptotic process  (ISO)
negative regulation of endothelial cell apoptotic process  (ISO)
positive regulation of angiogenesis  (IEA,ISO)
positive regulation of cell adhesion  (ISO)
positive regulation of cytokine production involved in immune response  (ISO)
positive regulation of endothelial cell migration  (IEA)
positive regulation of ERK1 and ERK2 cascade  (IEA,ISO)
positive regulation of focal adhesion assembly  (IEA)
positive regulation of intracellular signal transduction  (IEA)
positive regulation of MAPK cascade  (IEA)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA,ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of protein phosphorylation  (IEA,ISO)
positive regulation of Rac protein signal transduction  (IEA)
positive regulation of Rho protein signal transduction  (IEA)
regulation of angiogenesis  (ISO)
regulation of cell migration  (ISO)
regulation of establishment or maintenance of cell polarity  (IEA)
regulation of non-canonical NF-kappaB signal transduction  (ISO)
response to cAMP  (ISO)
response to estrogen  (ISO)
response to hypoxia  (ISO)
response to peptide hormone  (ISO)
response to retinoic acid  (ISO)
sprouting angiogenesis  (IEA)
substrate adhesion-dependent cell spreading  (IEA)
Tie signaling pathway  (IEA)
vasculogenesis  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TEK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11145,278,375 - 45,377,300 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1145,278,891 - 45,409,093 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1143,955,919 - 44,054,831 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01146,225,355 - 46,324,241 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1146,225,693 - 46,324,239 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11144,881,654 - 44,980,440 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01144,771,574 - 44,870,410 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01145,518,478 - 45,616,970 (+)NCBIUU_Cfam_GSD_1.0
TEK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38927,109,141 - 27,230,178 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl927,109,141 - 27,230,174 (+)EnsemblGRCh38hg38GRCh38
GRCh37927,109,139 - 27,230,176 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36927,099,286 - 27,220,172 (+)NCBINCBI36Build 36hg18NCBI36
Build 34927,099,440 - 27,220,164NCBI
Celera927,037,320 - 27,158,328 (+)NCBICelera
Cytogenetic Map9p21.2NCBI
HuRef927,061,676 - 27,182,725 (+)NCBIHuRef
CHM1_1927,108,925 - 27,229,954 (+)NCBICHM1_1
T2T-CHM13v2.0927,119,713 - 27,240,739 (+)NCBIT2T-CHM13v2.0
Tek
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39494,627,322 - 94,763,213 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl494,627,526 - 94,763,213 (+)EnsemblGRCm39 Ensembl
GRCm38494,739,086 - 94,874,976 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl494,739,289 - 94,874,976 (+)EnsemblGRCm38mm10GRCm38
MGSCv37494,405,991 - 94,541,630 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36494,231,318 - 94,366,957 (+)NCBIMGSCv36mm8
Celera493,148,719 - 93,271,150 (+)NCBICelera
Cytogenetic Map4C5NCBI
cM Map443.34NCBI
Tek
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85114,722,815 - 114,849,535 (+)NCBIGRCr8
mRatBN7.25109,607,077 - 109,733,805 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5109,607,077 - 109,733,804 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5112,185,658 - 112,306,395 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05113,911,456 - 114,031,907 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05113,973,696 - 114,094,435 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05113,725,717 - 113,852,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5113,725,717 - 113,852,799 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05117,672,484 - 117,799,345 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45115,047,195 - 115,196,172 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15115,171,316 - 115,174,864 (+)NCBI
Celera5108,234,353 - 108,354,536 (+)NCBICelera
Cytogenetic Map5q33NCBI
Tek
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554727,633,721 - 7,748,386 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554727,633,790 - 7,748,130 (-)NCBIChiLan1.0ChiLan1.0
TEK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21197,313,642 - 97,436,178 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1997,319,581 - 97,442,141 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0926,955,339 - 27,077,809 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1927,561,421 - 27,683,572 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl927,561,421 - 27,683,572 (+)Ensemblpanpan1.1panPan2
Tek
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947160,136,641 - 160,248,238 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366112,420,172 - 2,531,722 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366112,420,176 - 2,531,726 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1195,937,432 - 196,051,980 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11195,938,177 - 196,052,294 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,224,152 - 218,293,514 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Tek
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473631,345,774 - 31,473,727 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TEK
830 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 5 16 1 6 1 5 10 6
Low 4 6 5 5 6 6 7 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005626696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005626697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038490457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038490458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038490459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038490460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038552567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038552568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038552569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038552570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038654552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038654561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038681898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038681899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038681900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038681901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF282848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG932085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000002677   ⟹   ENSCAFP00000002485
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1145,278,891 - 45,409,093 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000070398   ⟹   ENSCAFP00000045200
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1145,278,891 - 45,409,093 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000077424   ⟹   ENSCAFP00000048948
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1145,278,891 - 45,409,093 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000079839   ⟹   ENSCAFP00000056219
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1145,278,891 - 45,409,093 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000084672   ⟹   ENSCAFP00000065701
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1145,278,891 - 45,409,093 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000087729   ⟹   ENSCAFP00000047151
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1145,278,891 - 45,409,093 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845031961   ⟹   ENSCAFP00845024994
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1146,225,693 - 46,324,239 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032103   ⟹   ENSCAFP00845025101
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1146,225,867 - 46,324,239 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032205   ⟹   ENSCAFP00845025176
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1146,258,331 - 46,324,239 (+)Ensembl
RefSeq Acc Id: XM_005626696   ⟹   XP_005626753
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11145,278,375 - 45,377,300 (+)NCBI
Dog10K_Boxer_Tasha1143,955,922 - 44,054,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005626697   ⟹   XP_005626754
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11145,278,375 - 45,377,300 (+)NCBI
Dog10K_Boxer_Tasha1143,955,922 - 44,054,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038490457   ⟹   XP_038346385
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11144,881,654 - 44,980,440 (+)NCBI
RefSeq Acc Id: XM_038490458   ⟹   XP_038346386
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11144,881,655 - 44,980,440 (+)NCBI
RefSeq Acc Id: XM_038490459   ⟹   XP_038346387
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11144,881,657 - 44,980,440 (+)NCBI
RefSeq Acc Id: XM_038490460   ⟹   XP_038346388
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11144,881,657 - 44,980,440 (+)NCBI
RefSeq Acc Id: XM_038552567   ⟹   XP_038408495
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01145,518,478 - 45,616,970 (+)NCBI
RefSeq Acc Id: XM_038552568   ⟹   XP_038408496
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01145,518,479 - 45,616,970 (+)NCBI
RefSeq Acc Id: XM_038552569   ⟹   XP_038408497
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01145,518,481 - 45,616,970 (+)NCBI
RefSeq Acc Id: XM_038552570   ⟹   XP_038408498
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01145,518,481 - 45,616,970 (+)NCBI
RefSeq Acc Id: XM_038616428   ⟹   XP_038472356
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01144,771,574 - 44,870,410 (+)NCBI
RefSeq Acc Id: XM_038616429   ⟹   XP_038472357
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01144,771,575 - 44,870,410 (+)NCBI
RefSeq Acc Id: XM_038616430   ⟹   XP_038472358
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01144,771,577 - 44,870,410 (+)NCBI
RefSeq Acc Id: XM_038616431   ⟹   XP_038472359
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01144,771,577 - 44,870,410 (+)NCBI
RefSeq Acc Id: XM_038654552   ⟹   XP_038510480
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1143,955,919 - 44,054,831 (+)NCBI
RefSeq Acc Id: XM_038654561   ⟹   XP_038510489
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1143,955,920 - 44,054,831 (+)NCBI
RefSeq Acc Id: XM_038681898   ⟹   XP_038537826
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01146,225,355 - 46,324,241 (+)NCBI
RefSeq Acc Id: XM_038681899   ⟹   XP_038537827
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01146,225,356 - 46,324,241 (+)NCBI
RefSeq Acc Id: XM_038681900   ⟹   XP_038537828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01146,225,358 - 46,324,241 (+)NCBI
RefSeq Acc Id: XM_038681901   ⟹   XP_038537829
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01146,225,358 - 46,324,241 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005626753 (Get FASTA)   NCBI Sequence Viewer  
  XP_005626754 (Get FASTA)   NCBI Sequence Viewer  
  XP_038346385 (Get FASTA)   NCBI Sequence Viewer  
  XP_038346386 (Get FASTA)   NCBI Sequence Viewer  
  XP_038346387 (Get FASTA)   NCBI Sequence Viewer  
  XP_038346388 (Get FASTA)   NCBI Sequence Viewer  
  XP_038408495 (Get FASTA)   NCBI Sequence Viewer  
  XP_038408496 (Get FASTA)   NCBI Sequence Viewer  
  XP_038408497 (Get FASTA)   NCBI Sequence Viewer  
  XP_038408498 (Get FASTA)   NCBI Sequence Viewer  
  XP_038472356 (Get FASTA)   NCBI Sequence Viewer  
  XP_038472357 (Get FASTA)   NCBI Sequence Viewer  
  XP_038472358 (Get FASTA)   NCBI Sequence Viewer  
  XP_038472359 (Get FASTA)   NCBI Sequence Viewer  
  XP_038510480 (Get FASTA)   NCBI Sequence Viewer  
  XP_038510489 (Get FASTA)   NCBI Sequence Viewer  
  XP_038537826 (Get FASTA)   NCBI Sequence Viewer  
  XP_038537827 (Get FASTA)   NCBI Sequence Viewer  
  XP_038537828 (Get FASTA)   NCBI Sequence Viewer  
  XP_038537829 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF97238 (Get FASTA)   NCBI Sequence Viewer  
  AWA46075 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000002485.5
  ENSCAFP00000045200.1
  ENSCAFP00000047151.2
  ENSCAFP00000056219.2
  ENSCAFP00030014988.1
  ENSCAFP00030015140.1
  ENSCAFP00030015189.1
  ENSCAFP00040008708.1
  ENSCAFP00040008770.1
  ENSCAFP00040008828.1
  ENSCAFP00040008890.1
  ENSCAFP00040008965.1
  ENSCAFP00040008991.1
  ENSCAFP00845024994
  ENSCAFP00845024994.1
  ENSCAFP00845025101.1
  ENSCAFP00845025176.1
Reference Protein Sequences
RefSeq Acc Id: XP_005626753   ⟸   XM_005626696
- Peptide Label: isoform X3
- UniProtKB: A0A8C0MPR3 (UniProtKB/TrEMBL),   A0A8C0KNZ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005626754   ⟸   XM_005626697
- Peptide Label: isoform X4
- UniProtKB: A0A8I3P3D4 (UniProtKB/TrEMBL),   A0A8P0N4V0 (UniProtKB/TrEMBL),   A0A8C0KNZ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000065701   ⟸   ENSCAFT00000084672
RefSeq Acc Id: ENSCAFP00000045200   ⟸   ENSCAFT00000070398
RefSeq Acc Id: ENSCAFP00000048948   ⟸   ENSCAFT00000077424
RefSeq Acc Id: ENSCAFP00000047151   ⟸   ENSCAFT00000087729
RefSeq Acc Id: ENSCAFP00000056219   ⟸   ENSCAFT00000079839
RefSeq Acc Id: ENSCAFP00000002485   ⟸   ENSCAFT00000002677
RefSeq Acc Id: XP_038346385   ⟸   XM_038490457
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038346386   ⟸   XM_038490458
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038346387   ⟸   XM_038490459
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038346388   ⟸   XM_038490460
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038472356   ⟸   XM_038616428
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038472357   ⟸   XM_038616429
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038472358   ⟸   XM_038616430
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038472359   ⟸   XM_038616431
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038537826   ⟸   XM_038681898
- Peptide Label: isoform X1
- UniProtKB: A0A8P0T060 (UniProtKB/TrEMBL),   A0A8C0KNZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038537827   ⟸   XM_038681899
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038537828   ⟸   XM_038681900
- Peptide Label: isoform X3
- UniProtKB: A0A8C0MPR3 (UniProtKB/TrEMBL),   A0A8C0KNZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038537829   ⟸   XM_038681901
- Peptide Label: isoform X4
- UniProtKB: A0A8I3P3D4 (UniProtKB/TrEMBL),   A0A8P0N4V0 (UniProtKB/TrEMBL),   A0A8C0KNZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038510480   ⟸   XM_038654552
- Peptide Label: isoform X1
- UniProtKB: A0A8P0T060 (UniProtKB/TrEMBL),   A0A8C0KNZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038510489   ⟸   XM_038654561
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038408495   ⟸   XM_038552567
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KNZ4 (UniProtKB/TrEMBL),   A0A8P0T060 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038408496   ⟸   XM_038552568
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038408497   ⟸   XM_038552569
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KNZ4 (UniProtKB/TrEMBL),   A0A8C0MPR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038408498   ⟸   XM_038552570
- Peptide Label: isoform X4
- UniProtKB: A0A8C0KNZ4 (UniProtKB/TrEMBL),   A0A8I3P3D4 (UniProtKB/TrEMBL),   A0A8P0N4V0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845024994   ⟸   ENSCAFT00845031961
RefSeq Acc Id: ENSCAFP00845025176   ⟸   ENSCAFT00845032205
RefSeq Acc Id: ENSCAFP00845025101   ⟸   ENSCAFT00845032103
Protein Domains
EGF-like   Fibronectin type-III   Ig-like   Protein kinase

Promoters
RGD ID:13685222
Promoter ID:EPDNEW_C3289
Type:initiation region
Name:TEK_1
Description:TEK receptor tyrosine kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11145,278,751 - 45,278,811EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001713 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030008950 UniProtKB/TrEMBL
  ENSCAFG00040005352 UniProtKB/TrEMBL
  ENSCAFG00845018055 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002677.5 UniProtKB/TrEMBL
  ENSCAFT00000070398.2 UniProtKB/TrEMBL
  ENSCAFT00000079839.2 UniProtKB/TrEMBL
  ENSCAFT00000087729.2 UniProtKB/TrEMBL
  ENSCAFT00030017153.1 UniProtKB/TrEMBL
  ENSCAFT00030017334.1 UniProtKB/TrEMBL
  ENSCAFT00030017397.1 UniProtKB/TrEMBL
  ENSCAFT00040010048.1 UniProtKB/TrEMBL
  ENSCAFT00040010112.1 UniProtKB/TrEMBL
  ENSCAFT00040010177.1 UniProtKB/TrEMBL
  ENSCAFT00040010244.1 UniProtKB/TrEMBL
  ENSCAFT00040010332.1 UniProtKB/TrEMBL
  ENSCAFT00040010359.1 UniProtKB/TrEMBL
  ENSCAFT00845031961 ENTREZGENE
  ENSCAFT00845031961.1 UniProtKB/TrEMBL
  ENSCAFT00845032103.1 UniProtKB/TrEMBL
  ENSCAFT00845032205.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  EGF_extracell UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  LE_dom UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kin_Tie2_Ig-like_dom-1_N UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
KEGG Report cfa:403714 UniProtKB/TrEMBL
NCBI Gene TEK ENTREZGENE
PANTHER ANGIOPOIETIN-1 RECEPTOR UniProtKB/TrEMBL
  INACTIVE TYROSINE-PROTEIN KINASE 7 UniProtKB/TrEMBL
  PROTEIN KINASE RECEPTOR TIE-1, PUTATIVE-RELATED UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/TrEMBL
Pfam EGF_2 UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  Ig_Tie2_1 UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PIRSF TyrPK_CSF1-R UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A2S0RR57_CANLF UniProtKB/TrEMBL
  A0A8C0KNZ4 ENTREZGENE
  A0A8C0MPR3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q5H5_CANLF UniProtKB/TrEMBL
  A0A8C0Q5M0_CANLF UniProtKB/TrEMBL
  A0A8C0QDC6_CANLF UniProtKB/TrEMBL
  A0A8C0QH76_CANLF UniProtKB/TrEMBL
  A0A8C0QKW3_CANLF UniProtKB/TrEMBL
  A0A8I3P3D4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PCR2_CANLF UniProtKB/TrEMBL
  A0A8I3S0B4_CANLF UniProtKB/TrEMBL
  A0A8P0N4V0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0T060 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47241 ENTREZGENE