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Gene: Ehhadh (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase) Rattus norvegicus
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Symbol: Ehhadh
Name: enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
Description: Exhibits 3-hydroxyacyl-CoA dehydrogenase activity and enzyme binding activity. Predicted to be involved in fatty acid beta-oxidation and internal protein amino acid acetylation. Localizes to the cytosol and peroxisome. Human ortholog(s) of this gene implicated in Fanconi syndrome. Orthologous to human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase); PARTICIPATES IN valproic acid pharmacokinetics pathway; beta-alanine metabolic pathway; butanoate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase; L-specific bifunctional protein; LBP; MEF; Mfe; Mfe1; multifunctional enzyme type 1; PBE; PBFE; pe-CoA; perMFE-1; peroxisomal bifunctional enzyme; peroxisomal bifunctional enzyme type 1; peroxisomal enoyl-CoA/hydrotase-3-hydroxyacyl-CoA
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01182,945,104 - 82,978,364 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01186,024,803 - 86,057,811 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,474,161 - 81,507,645 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11181,531,749 - 81,565,234 (+)NCBI
Celera1178,098,443 - 78,131,686 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ehhadh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621441
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.