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Gene: Ocln (occludin) Rattus norvegicus
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Symbol: Ocln
Name: occludin
Description: Predicted to have protein domain specific binding activity. Involved in cellular response to tumor necrosis factor and response to interleukin-18. Localizes to the apical plasma membrane and lateral plasma membrane. Biomarker of diabetic retinopathy. Human ortholog(s) of this gene implicated in Crohn's disease and pseudo-TORCH syndrome 1. Orthologous to human OCLN (occludin); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; hepatitis C pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 17-glucosiduronic acid; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Orthologs:
Homo sapiens (human) : OCLN (occludin)  HGNC  Alliance
Mus musculus (house mouse) : Ocln (occludin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ocln (occludin)
Pan paniscus (bonobo/pygmy chimpanzee) : OCLN (occludin)
Canis lupus familiaris (dog) : OCLN (occludin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ocln (occludin)
Sus scrofa (pig) : OCLN (occludin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0230,527,327 - 30,577,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0249,686,707 - 49,737,380 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4231,317,090 - 31,367,485 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1231,237,461 - 31,287,854 (-)NCBI
Celera227,670,881 - 27,719,967 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ocln
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620089
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.