Gene: Nus1 (NUS1 dehydrodolichyl diphosphate synthase subunit) Rattus norvegicus
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Symbol: Nus1
Name: NUS1 dehydrodolichyl diphosphate synthase subunit
Description: ENCODES a protein that exhibits dehydrodolichyl diphosphate synthase activity (ortholog); prenyltransferase activity (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); dolichol biosynthetic process (ortholog); dolichyl diphosphate biosynthetic process (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant mental retardation 55 (ortholog); body dysmorphic disorder (ortholog); FOUND IN dehydrodolichyl diphosphate synthase complex (ortholog); endoplasmic reticulum membrane (ortholog); membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; dibutyl phthalate
AGR Description: Predicted to have dehydrodolichyl diphosphate synthase activity; predicted to be involved in several processes, including cholesterol homeostasis, dolichol biosynthetic process, and protein glycosylation; predicted to localize to the dehydrodolichyl diphosphate synthase complex and endoplasmic reticulum membrane; orthologous to human NUS1 (NUS1 dehydrodolichyl diphosphate synthase subunit).
Merged Description: Predicted to have dehydrodolichyl diphosphate synthase activity; predicted to be involved in several processes, including cholesterol homeostasis, dolichol biosynthetic process, and protein glycosylation; predicted to localize to the dehydrodolichyl diphosphate synthase complex and endoplasmic reticulum membrane; orthologous to human NUS1 (NUS1 dehydrodolichyl diphosphate synthase subunit); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dehydrodolichyl diphosphate synthase complex subunit NUS1; LOC294400; nogo-B receptor; nuclear undecaprenyl pyrophosphate synthase 1; nuclear undecaprenyl pyrophosphate synthase 1 homolog; nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); RGD1307879; similar to hypothetical protein D10Ertd438e
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02033,557,052 - 33,584,011 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02035,336,831 - 35,363,790 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42031,143,886 - 31,170,668 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12031,144,058 - 31,181,953 (+)NCBI
Celera2033,209,636 - 33,236,417 (+)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nus1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307879
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.