Gstt1 (glutathione S-transferase theta 1) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Gstt1 (glutathione S-transferase theta 1) Rattus norvegicus
Analyze
Symbol: Gstt1
Name: glutathione S-transferase theta 1
RGD ID: 2765
Description: Exhibits alkylhalidase activity; glutathione peroxidase activity; and glutathione transferase activity. Involved in several processes, including dichloromethane metabolic process; response to selenium ion; and response to vitamin E. Localizes to cytosol and nucleus. Biomarker of obesity and type 1 diabetes mellitus; PARTICIPATES IN glutathione conjugation pathway; paracetamol pharmacokinetics pathway; glutathione metabolic pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; (E)-1,3-dichloropropene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Glutathione S-transferase 1 (theta); glutathione S-transferase 5; glutathione S-transferase theta-1; glutathione S-transferase, theta 1; GST 5-5; GST class-theta-1; GSTYRS
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22012,856,613 - 12,873,586 (+)NCBI
Rnor_6.0 Ensembl2013,799,102 - 13,816,526 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02013,799,102 - 13,816,527 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02015,989,083 - 16,006,508 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,604,355 - 13,621,456 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12013,604,582 - 13,621,683 (-)NCBI
Celera2014,348,088 - 14,365,283 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute chest syndrome  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
acute promyelocytic leukemia  (ISO)
Agammaglobulinemia 2, Autosomal Recessive  (ISO)
aggressive periodontitis  (ISO)
alcohol dependence  (ISO)
Alcoholic Liver Diseases  (ISO)
Alzheimer's disease  (ISO)
amphetamine abuse  (ISO)
anemia  (ISO)
aplastic anemia  (ISO)
asbestosis  (ISO)
Asthenozoospermia  (ISO)
asthma  (ISO)
atopic dermatitis  (ISO)
beta thalassemia  (ISO)
breast cancer  (ISO)
Bronchopulmonary Dysplasia  (ISO)
cancer  (ISO)
carcinoma  (ISO)
cardiovascular system disease  (ISO)
cataract  (ISO)
cervical cancer  (ISO)
cervix carcinoma  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chromosome Aberrations  (ISO)
Chronic Bronchitis  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
colorectal adenocarcinoma  (ISO)
colorectal cancer  (ISO)
colorectal carcinoma  (ISO)
Congenital Abnormalities  (ISO)
congenital heart disease  (ISO)
coronary artery disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
cystic fibrosis  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
diffuse large B-cell lymphoma  (ISO)
disease of cellular proliferation  (ISO)
Disease Susceptibility  (ISO)
drug allergy  (ISO)
Drug-induced Anemia  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
Drug-Induced Leukopenia  (ISO)
Drug-induced Neutropenia  (ISO)
end stage renal disease  (ISO)
epilepsy  (ISO)
Epistaxis  (ISO)
esophageal cancer  (ISO)
Esophageal Neoplasms  (ISO)
esophagus adenocarcinoma  (ISO)
esophagus squamous cell carcinoma  (ISO)
exfoliation syndrome  (ISO)
Fanconi anemia  (ISO)
Femur Head Necrosis  (ISO)
Fetal Growth Retardation  (ISO)
Fever  (ISO)
glioblastoma  (ISO)
head and neck cancer  (ISO)
Hearing Loss, Noise-Induced  (ISO)
Hematologic Neoplasms  (ISO)
hepatocellular carcinoma  (ISO)
Hirschsprung's disease  (ISO)
Hodgkin's lymphoma  (ISO)
hypertension  (ISO)
hypospadias  (ISO)
infectious mononucleosis  (ISO)
inflammatory bowel disease  (ISO)
Iron Overload  (ISO)
juvenile rheumatoid arthritis  (ISO)
Kidney Neoplasms  (ISO)
Kuhnt-Junius degeneration  (ISO)
leukemia  (ISO)
leukopenia  (ISO)
Leukoplakia  (ISO)
liver cirrhosis  (ISO)
liver disease  (ISO)
lung cancer  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lymphoid leukemia  (ISO)
Lynch syndrome  (ISO)
medulloblastoma  (ISO)
Micronuclei, Chromosome-Defective  (ISO)
motor neuron disease  (ISO)
Mouth Abnormalities  (ISO)
mucositis  (ISO)
multiple myeloma  (ISO)
multiple sclerosis  (ISO)
myelodysplastic syndrome  (ISO)
myeloid leukemia  (ISO)
Nasal Polyps  (ISO)
neutropenia  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (IEP)
optic neuritis  (ISO)
oral cavity cancer  (ISO)
oral mucosa leukoplakia  (ISO)
oral submucous fibrosis  (ISO)
orofacial cleft  (ISO)
ovary epithelial cancer  (ISO)
pancreatic adenocarcinoma  (ISO)
Parkinson's disease  (ISO)
Perinatal Asphyxia  (ISO)
peripheral nervous system disease  (ISO)
pre-malignant neoplasm  (ISO)
Premature Birth  (ISO)
Presbycusis  (ISO)
primary open angle glaucoma  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary tuberculosis  (ISO)
Raynaud disease  (ISO)
renal cell carcinoma  (ISO)
rheumatoid arthritis  (ISO)
senile cataract  (ISO)
sickle cell anemia  (ISO)
skin melanoma  (ISO)
Skin Neoplasms  (ISO)
stomach cancer  (ISO)
Therapy-related Acute Myeloid Leukemia  (ISO)
transitional cell carcinoma  (ISO)
Transplant Rejection  (ISO)
type 1 diabetes mellitus  (IEP)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
Vaso-occlusive Crisis  (ISO)
venous insufficiency  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (EXP)
(+)-schisandrin B  (EXP)
(E)-1,3-dichloropropene  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,2-dibromoethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1,2-epoxy-3-(4-nitrophenoxy)propane  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4,6-trinitrotoluene  (EXP)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-amino-7-methyl-1,7-dihydro-6H-purin-6-one  (ISO)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
acetylsalicylic acid  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
amphotericin B  (EXP)
angelica lactone  (EXP)
aristolochic acid  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
atrazine  (EXP)
benzbromarone  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzyl isothiocyanate  (EXP)
beta-D-glucosamine  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
bromodichloromethane  (EXP,ISO)
bromomethane  (ISO)
busulfan  (ISO)
buta-1,3-diene  (ISO)
butylated hydroxyanisole  (EXP)
cadmium dichloride  (EXP)
carbamazepine  (ISO)
carbon disulfide  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
chloroethene  (ISO)
chlorohydrocarbon  (ISO)
chloromethane  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (EXP)
cumene hydroperoxide  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (ISO)
Deoxycorticosterone acetate  (EXP)
dexamethasone  (EXP,ISO)
Diallyl sulfide  (EXP)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibromomethane  (EXP,ISO)
dichloromethane  (EXP,ISO)
diclofenac  (ISO)
diepoxybutane  (EXP,ISO)
diethyl maleate  (EXP)
dimethylarsinic acid  (ISO)
disodium selenite  (ISO)
elemental selenium  (EXP)
ellagic acid  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethoxyquin  (EXP,ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
glutathione  (EXP,ISO)
graphite  (EXP)
herbicide  (EXP)
hydrogen peroxide  (ISO)
ibuprofen  (EXP)
indole-3-methanol  (EXP)
indometacin  (EXP)
isoniazide  (ISO)
isothiocyanate  (ISO)
L-ascorbic acid  (ISO)
L-ethionine  (EXP)
lead nitrate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (ISO)
malonaldehyde  (ISO)
MeIQx  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methamphetamine  (ISO)
methimazole  (EXP)
methoxyacetic acid  (EXP)
methylarsonic acid  (ISO)
microcystin  (EXP)
microcystin RR  (ISO)
microcystin-LR  (ISO)
muconic acid  (ISO)
N-ethyl-N-nitrosourea  (ISO)
naphthalene  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel subsulfide  (ISO)
nitrogen dioxide  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP)
oltipraz  (EXP)
omeprazole  (EXP)
oxirane  (ISO)
ozone  (ISO)
p-nitrobenzyl chloride  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion-methyl  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (EXP,ISO)
PhIP  (ISO)
phlorizin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (EXP)
potassium chloride  (EXP)
potassium dichromate  (ISO)
progesterone  (ISO)
propargite  (ISO)
propiconazole  (ISO)
pyrazinecarboxamide  (ISO)
quercetin  (ISO)
rifampicin  (ISO)
selenium atom  (EXP)
senecionine  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sterigmatocystin  (EXP)
stilbene oxide  (EXP)
styrene  (ISO)
styrene oxide  (ISO)
sulforaphane  (EXP,ISO)
sulindac  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thiabendazole  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
triadimefon  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (EXP)
troglitazone  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (EXP)
xanthohumol  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytosol  (IDA,ISO)
nucleus  (IDA)

Molecular Function

References

References - curated
1. Abbas A, etal., World J Gastroenterol. 2004 Dec 1;10(23):3389-93.
2. Abu-Amero KK, etal., BMC Med Genet. 2006 Apr 19;7:38.
3. Abu-Amero KK, etal., Br J Ophthalmol. 2009 Aug;93(8):1101-4. Epub 2009 Mar 13.
4. Angeli SI, etal., Laryngoscope. 2012 Nov;122(11):2539-42. doi: 10.1002/lary.23577. Epub 2012 Sep 10.
5. Arruda VR, etal., Eur J Haematol. 2001 Jun;66(6):383-8.
6. Asim M, etal., Dis Markers. 2010;28(6):369-76. doi: 10.3233/DMA-2010-0717.
7. Ates NA, etal., Otol Neurotol. 2005 May;26(3):392-7.
8. Barahmani N, etal., Neuro Oncol. 2009 Jun;11(3):292-300. Epub 2008 Oct 24.
9. Barroso Duarte EC, etal., Anticancer Res. 2006 Jan-Feb;26(1A):427-30.
10. Basu T, etal., Lancet. 1997 May 17;349(9063):1450.
11. Berendsen CL, etal., Urology. 1997 Apr;49(4):644-51.
12. Bogdani M, etal., J Endocrinol. 2013 Jan 18;216(2):111-23. doi: 10.1530/JOE-12-0385. Print 2013 Feb.
13. Bohanec Grabar P, etal., Clin Exp Rheumatol. 2009 Mar-Apr;27(2):229-36.
14. Bolufer P, etal., Br J Haematol. 2007 Feb;136(4):590-6.
15. Brasch-Andersen C, etal., Hum Mutat. 2004 Sep;24(3):208-14.
16. Buentello-Volante B, etal., Exp Eye Res. 2013 Feb;107:59-64. doi: 10.1016/j.exer.2012.11.013. Epub 2012 Nov 30.
17. Buzio L, etal., Occup Environ Med. 2003 Oct;60(10):789-93.
18. Cai L, etal., World J Gastroenterol. 2001 Aug;7(4):506-9. doi: 10.3748/wjg.v7.i4.506.
19. Carlsson PI, etal., Hear Res. 2005 Apr;202(1-2):87-96.
20. Casson AG, etal., Cancer Detect Prev. 2006;30(5):423-31. Epub 2006 Oct 24.
21. Chen H, etal., Lancet. 1996 Feb 3;347(8997):295-7.
22. Chen HC, etal., Eur J Cancer Prev. 2008 Jun;17(3):251-8. doi: 10.1097/CEJ.0b013e3282b72093.
23. Chen J, etal., Mol Biol Rep. 2012 Dec;39(12):10383-93. doi: 10.1007/s11033-012-1917-0. Epub 2012 Oct 10.
24. Cho HJ, etal., Cancer Genet Cytogenet. 2010 Apr 1;198(1):40-6. doi: 10.1016/j.cancergencyto.2009.12.004.
25. Chung J, etal., Clin Chem Lab Med. 2009;47(12):1475-81.
26. Cibeira MT, etal., Leuk Res. 2011 Sep;35(9):1178-83. doi: 10.1016/j.leukres.2011.02.009. Epub 2011 Mar 23.
27. Concolino P, etal., Clin Biochem. 2007 Sep;40(13-14):939-45. doi: 10.1016/j.clinbiochem.2007.04.012. Epub 2007 Apr 27.
28. Cresci M, etal., Am J Cardiol. 2011 Dec 1;108(11):1625-31. doi: 10.1016/j.amjcard.2011.07.022. Epub 2011 Sep 3.
29. Davies SM, etal., Br J Haematol. 2005 Oct;131(1):118-22.
30. de Lima Marson FA, etal., BMC Med Genet. 2013 Jun 10;14:60. doi: 10.1186/1471-2350-14-60.
31. de Oliveira Filho RA, etal., Blood Cells Mol Dis. 2013 Aug;51(2):76-9. doi: 10.1016/j.bcmd.2013.03.003. Epub 2013 Apr 13.
32. Delpisheh A, etal., Eur J Obstet Gynecol Reprod Biol. 2009 Mar;143(1):38-42. doi: 10.1016/j.ejogrb.2008.11.006. Epub 2009 Jan 14.
33. Dirksen U, etal., Pediatr Res. 2004 Mar;55(3):466-71. Epub 2003 Dec 17.
34. Doney AS, etal., Circulation. 2005 Jun 7;111(22):2927-34. Epub 2005 May 31.
35. Duarte EC, etal., Anticancer Res. 2008 Mar-Apr;28(2A):1101-6.
36. Duell EJ, etal., J Natl Cancer Inst. 2002 Feb 20;94(4):297-306. doi: 10.1093/jnci/94.4.297.
37. Elhasid R, etal., Bone Marrow Transplant. 2010 Dec;45(12):1728-31. doi: 10.1038/bmt.2010.61. Epub 2010 Mar 29.
38. Faramawy MM, etal., J Crit Care. 2009 Sep;24(3):e7-10.
39. Gao H, etal., Int J Colorectal Dis. 2011 Jan;26(1):117-25. doi: 10.1007/s00384-010-1013-7. Epub 2010 Jul 27.
40. Garcia-Closas M, etal., J Natl Cancer Inst. 1999 Nov 17;91(22):1960-4.
41. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
42. Ghelani AM, etal., Rheumatol Int. 2010 Apr 18.
43. Ghosh T, etal., Mol Biol Rep. 2012 Oct;39(10):9383-9. doi: 10.1007/s11033-012-1802-x. Epub 2012 Jul 1.
44. Giannouli S and Voulgarelis M, Leuk Res. 2013 Oct;37(10):1185-6. doi: 10.1016/j.leukres.2013.06.001. Epub 2013 Jul 13.
45. Gisi D, etal., Eur J Biochem. 2001 Jul;268(14):4001-10.
46. GOA data from the GO Consortium
47. Goncalves MS, etal., Int J Lab Hematol. 2010 Feb;32(1 Pt 1):e49-56. doi: 10.1111/j.1751-553X.2009.01169.x. Epub 2009 Jun 23.
48. Gordeeva LA, etal., Prenat Diagn. 2013 Nov;33(11):1095-101. doi: 10.1002/pd.4204. Epub 2013 Aug 24.
49. Gorovenko NG, etal., Tsitol Genet. 2010 Sep-Oct;44(5):41-6.
50. Gra OA, etal., Genetika. 2010 Feb;46(2):262-71.
51. Guo L, etal., Hua Xi Kou Qiang Yi Xue Za Zhi. 2012 Apr;30(2):187-91.
52. Haase D, etal., Leuk Res. 2002 Mar;26(3):249-54.
53. Hayek T, etal., Atherosclerosis. 2006 Feb;184(2):404-12. Epub 2005 Jul 5.
54. Hiratsuka A, etal., Anal Biochem. 1997 Oct 15;252(2):229-37.
55. Hori M, etal., Pharmacogenomics. 2007 Oct;8(10):1307-14.
56. Hovnik T, etal., Diabetes Care. 2009 Dec;32(12):2258-62. doi: 10.2337/dc09-0852. Epub 2009 Sep 14.
57. Huang W, etal., Gene. 2013 Sep 10;526(2):80-6. doi: 10.1016/j.gene.2013.05.032. Epub 2013 Jun 4.
58. Ibrahim AM, etal., Ann Hum Genet. 2016 Jan;80(1):32-7. doi: 10.1111/ahg.12138. Epub 2015 Nov 9.
59. Jonsson LS, etal., Int Arch Occup Environ Health. 2008 Jul;81(7):913-9. Epub 2007 Dec 8.
60. Kanetsky PA, etal., Cancer Epidemiol Biomarkers Prev. 2001 May;10(5):509-13.
61. Kao CC, etal., J Surg Oncol. 2010 Sep 15;102(4):301-7. doi: 10.1002/jso.21643.
62. Karban A, etal., Dig Dis Sci. 2011 Jul;56(7):2081-7. Epub 2011 Jan 18.
63. Keenan BT, etal., Arthritis Rheum. 2010 Nov;62(11):3196-210. doi: 10.1002/art.27639.
64. Khan MI, etal., Mol Vis. 2010 Oct 26;16:2146-52.
65. Kim JW, etal., Cancer. 2000 May 1;88(9):2082-91.
66. Korytina GF, etal., J Mol Med. 2005 Sep;83(9):700-10. Epub 2005 Jun 1.
67. Ladero JM, etal., Scand J Gastroenterol. 2005 Mar;40(3):348-53. doi: 10.1080/00365520510012109.
68. Lee HS, etal., Leuk Res. 2009 Mar;33(3):426-33. doi: 10.1016/j.leukres.2008.07.021. Epub 2008 Aug 29.
69. Li YH, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2012 Apr;14(4):260-3.
70. Lie RT, etal., Epidemiology. 2008 Jul;19(4):606-15. doi: 10.1097/EDE.0b013e3181690731.
71. Lima CS, etal., J Bras Pneumol. 2012 Jan-Feb;38(1):50-6. doi: 10.1590/s1806-37132012000100008.
72. Lincz LF, etal., Haematologica. 2004 May;89(5):628-9.
73. Lourenco GJ, etal., Eur J Haematol. 2005 Dec;75(6):530-1.
74. Lu Y, etal., Gene. 2013 Sep 15;527(1):311-5. doi: 10.1016/j.gene.2013.06.031. Epub 2013 Jul 1.
75. Makhdoomi MA, etal., Tumour Biol. 2015 Apr;36(4):2613-9. doi: 10.1007/s13277-014-2882-0. Epub 2014 Nov 29.
76. Mallick S, etal., Urology. 2007 Jun;69(6):1165-9.
77. Mandegary A, etal., Asian Pac J Cancer Prev. 2011;12(5):1279-82.
78. Manfredi S, etal., Pharmacogenomics. 2009 Jan;10(1):29-34.
79. Mann CL, etal., Neurology. 2000 Feb 8;54(3):552-7.
80. Mansoori AA and Jain SK, Asian Pac J Cancer Prev. 2018 Mar 27;19(3):725-731. doi: 10.22034/APJCP.2018.19.3.725.
81. Marson FA, etal., BMC Med Genet. 2014 Mar 4;15:27. doi: 10.1186/1471-2350-15-27.
82. Martínez C, etal., J Infect Dis. 2007 May 1;195(9):1320-3. doi: 10.1086/513569. Epub 2007 Mar 15.
83. Martínez C, etal., Pharmacogenomics. 2006 Jul;7(5):711-8. doi: 10.2217/14622416.7.5.711.
84. Martínez-Bravo MJ, etal., Immunol Lett. 2011 Dec 30;141(1):140-4. doi: 10.1016/j.imlet.2011.09.005. Epub 2011 Sep 24.
85. Masood N, etal., Cancer Biomark. 2015;15(5):583-9. doi: 10.3233/CBM-150498.
86. McLeod R, etal., Cancer Res. 1997 Oct 1;57(19):4257-66.
87. Mehrotra S, etal., Int J Immunogenet. 2010 Aug;37(4):263-7. Epub 2010 Apr 6.
88. MGD data from the GO Consortium
89. Mittal RD, etal., J Gastroenterol Hepatol. 2007 Jun;22(6):920-4.
90. Moisio AL, etal., Gastroenterology. 1998 Dec;115(6):1387-94.
91. Moore LE, etal., Carcinogenesis. 2007 Sep;28(9):1960-4. Epub 2007 Jul 7.
92. Morabito F, etal., Leuk Lymphoma. 2012 Mar;53(3):406-10. doi: 10.3109/10428194.2011.623254.
93. Mustafa MD, etal., Mol Hum Reprod. 2013 Jan;19(1):35-42. doi: 10.1093/molehr/gas039. Epub 2012 Sep 3.
94. Nagle CM, etal., Eur J Cancer. 2007 Jan;43(2):283-90. Epub 2006 Nov 3.
95. Nascimento H, etal., Dis Colon Rectum. 2003 Apr;46(4):510-5. doi: 10.1007/s10350-004-6591-4.
96. NCBI rat LocusLink and RefSeq merged data July 26, 2002
97. Negovan A, etal., Biomed Res Int. 2017;2017:7365080. doi: 10.1155/2017/7365080. Epub 2017 Jan 15.
98. Nosheen M, etal., Asian Pac J Cancer Prev. 2010;11(4):881-5.
99. Ogura K, etal., Biochem Biophys Res Commun 1991 Dec 31;181(3):1294-300.
100. Ogura K, etal., Biochem Biophys Res Commun 1994 Dec 15;205(2):1250-6.
101. Online Mendelian Inheritance in Man, OMIM (TM).
102. Ortega MM, etal., Acta Haematol. 2003;109(2):108-9.
103. Ovsepian VA, etal., Genetika. 2010 Oct;46(10):1360-2.
104. Oz O, etal., Eur J Ophthalmol. 2006 Jan - Feb;16(1):105-110. doi: 10.5301/EJO.2008.3524.
105. Ozcan C, etal., Eur Arch Otorhinolaryngol. 2010 Feb;267(2):227-32. Epub 2009 Aug 23.
106. Ozer HT, etal., Clin Exp Rheumatol. 2012 May-Jun;30(3 Suppl 72):S14-7. Epub 2012 Oct 8.
107. Pal M, etal., Tissue Cell. 2008 Dec;40(6):425-35. doi: 10.1016/j.tice.2008.04.003. Epub 2008 Jun 24.
108. Pemble SE and Taylor JB, Biochem J 1992 Nov 1;287 ( Pt 3):957-63.
109. Pipeline to import KEGG annotations from KEGG into RGD
110. Pipeline to import SMPDB annotations from SMPDB into RGD
111. Poonkuzhali B, etal., Acta Haematol. 2005;114(3):127-32.
112. Rajagopal R, etal., Carcinogenesis. 2005 Dec;26(12):2157-63. doi: 10.1093/carcin/bgi195. Epub 2005 Jul 28.
113. RGD automated data pipeline
114. RGD automated import pipeline for gene-chemical interactions
115. Rohr P, etal., Clin Exp Rheumatol. 2008 Jan-Feb;26(1):151-5.
116. Ross MK and Pegram RA, Chem Res Toxicol. 2003 Feb;16(2):216-26.
117. Rossini A, etal., Carcinogenesis. 2007 Dec;28(12):2537-42. doi: 10.1093/carcin/bgm222. Epub 2007 Oct 4.
118. Roy N, etal., PLoS One. 2016 Mar 3;11(3):e0149843. doi: 10.1371/journal.pone.0149843. eCollection 2016.
119. Rudolph A, etal., Int J Cancer. 2012 Sep 1;131(5):E841-8. doi: 10.1002/ijc.27428. Epub 2012 May 29.
120. Saadat I, etal., Mol Vis. 2012;18:1996-2000. Epub 2012 Jul 18.
121. Saadat M, Clin Chim Acta. 2020 May 23;508:213-216. doi: 10.1016/j.cca.2020.05.041.
122. Sanjay P, etal., Rev Bras Hematol Hemoter. 2012;34(2):100-2. doi: 10.5581/1516-8484.20120030.
123. Senhaji N, etal., Mediators Inflamm. 2015;2015:248060. doi: 10.1155/2015/248060. Epub 2015 Oct 28.
124. Sgambato A, etal., Anticancer Res. 2002 Nov-Dec;22(6B):3647-52.
125. Shaheen SO, etal., J Allergy Clin Immunol. 2010 Dec;126(6):1141-8.e7. Epub 2010 Nov 4.
126. Sharma A, etal., Tumour Biol. 2013 Oct;34(5):3249-57. doi: 10.1007/s13277-013-0897-6. Epub 2013 Jun 8.
127. Sharma E, etal., Eur J Obstet Gynecol Reprod Biol. 2012 Apr;161(2):163-9. doi: 10.1016/j.ejogrb.2012.01.008. Epub 2012 Feb 4.
128. Sharma V, etal., Ann Hematol. 2010 Apr;89(4):411-4. doi: 10.1007/s00277-009-0847-y. Epub 2009 Oct 17.
129. Shekharyadav C, etal., Hum Exp Toxicol. 2011 Oct;30(10):1464-74. doi: 10.1177/0960327110392402. Epub 2011 Feb 7.
130. Sherratt PJ, etal., Biochem J. 1998 Nov 1;335 ( Pt 3):619-30.
131. Shokeer A and Mannervik B, Biochim Biophys Acta. 2010 Apr;1800(4):466-73. doi: 10.1016/j.bbagen.2010.01.003. Epub 2010 Jan 25.
132. Sikdar N, etal., Int J Cancer. 2004 Mar;109(1):95-101. doi: 10.1002/ijc.11610.
133. Singh H, etal., Am J Obstet Gynecol. 2008 Mar;198(3):303.e1-6. Epub 2008 Feb 21.
134. Sireesha R, etal., Exp Eye Res. 2012 May;98:67-74. doi: 10.1016/j.exer.2012.03.002. Epub 2012 Mar 16.
135. Spalletta G, etal., Am J Geriatr Psychiatry. 2007 Oct;15(10):879-87.
136. Stanulla M, etal., Blood. 2000 Feb 15;95(4):1222-8.
137. Sterpone S, etal., Biol Res. 2009;42(4):477-86. doi: /S0716-97602009000400009. Epub 2010 Jan 29.
138. Strange RC, etal., Toxicol Lett 2000 Mar 15;112-113:357-63.
139. Stroombergen MC and Waring RH, Hum Exp Toxicol. 1999 Mar;18(3):141-5.
140. Takanashi M, etal., Haematologica. 2003 Nov;88(11):1238-44.
141. Tan EK, etal., Neurology. 2000 Aug 22;55(4):533-8.
142. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
143. Tew MB, etal., Genes Immun. 2001 Jun;2(4):236-8.
144. Tripathi S, etal., Indian J Gastroenterol. 2011 Dec;30(6):257-63. doi: 10.1007/s12664-011-0144-2. Epub 2011 Dec 3.
145. Tsai HJ, etal., Hum Genet. 2008 May;123(4):359-69. doi: 10.1007/s00439-008-0485-9. Epub 2008 Mar 5.
146. Tulsyan S, etal., Mol Diagn Ther. 2013 Dec;17(6):371-9. doi: 10.1007/s40291-013-0045-4.
147. Van Lieshout EM, etal., Biochim Biophys Acta. 1998 Aug 24;1381(3):305-11.
148. van Lieshout EM, etal., Carcinogenesis. 1998 Nov;19(11):2055-7.
149. van Rooij IA, etal., Epidemiology. 2001 Sep;12(5):502-7.
150. Vavilin VA, etal., Vopr Med Khim. 2000 Jul-Aug;46(4):388-97.
151. Wang X, etal., Gene. 2014 Jan 1;533(1):48-51. doi: 10.1016/j.gene.2013.10.004. Epub 2013 Oct 10.
152. Wang Y, etal., Cancer Epidemiol. 2010 Jun 7.
153. Waś J, etal., Adv Clin Exp Med. 2018 Nov;27(11):1561-1566. doi: 10.17219/acem/74682.
154. Westphal GA, etal., Int Arch Occup Environ Health. 2000 Aug;73(6):384-8.
155. Wilflingseder J, etal., Nephrol Dial Transplant. 2009 Mar;24(3):1015-23. doi: 10.1093/ndt/gfn683. Epub 2008 Dec 18.
156. Xiao Z, etal., Leuk Res. 2008 Aug;32(8):1288-91. Epub 2007 Nov 26.
157. Xu S, etal., Redox Rep. 2018 Dec;23(1):213-218. doi: 10.1080/13510002.2018.1546985.
158. Yang M, etal., Wei Sheng Yan Jiu. 2005 Nov;34(6):647-9.
159. Yang Y, etal., Int J Mol Med. 2004 Nov;14(5):855-9.
160. Yilmaz A, etal., Curr Eye Res. 2005 Jul;30(7):575-81.
161. Yuan JM, etal., Carcinogenesis. 2008 Jul;29(7):1386-93. Epub 2008 Jun 9.
162. Zenkel M, etal., Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5558-66.
163. Zhang L, etal., Biochem Pharmacol. 2019 Jun;164:368-376. doi: 10.1016/j.bcp.2019.05.002. Epub 2019 May 4.
164. Zhou J, etal., Invest Ophthalmol Vis Sci. 2010 Aug;51(8):3924-8. doi: 10.1167/iovs.10-5240. Epub 2010 Mar 24.
165. Zhu Y, etal., Zhonghua Nei Ke Za Zhi. 2002 Aug;41(8):538-40.
166. Živkovic M, etal., J Neurol Sci. 2013 Nov 15;334(1-2):6-9. doi: 10.1016/j.jns.2013.07.001. Epub 2013 Aug 9.
Additional References at PubMed
PMID:1848757   PMID:8670055   PMID:8761485   PMID:8799324   PMID:9307035   PMID:9434735   PMID:9854036   PMID:12038961   PMID:12477932   PMID:15489334   PMID:16496253   PMID:17827337  
PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Gstt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22012,856,613 - 12,873,586 (+)NCBI
Rnor_6.0 Ensembl2013,799,102 - 13,816,526 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02013,799,102 - 13,816,527 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02015,989,083 - 16,006,508 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,604,355 - 13,621,456 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12013,604,582 - 13,621,683 (-)NCBI
Celera2014,348,088 - 14,365,283 (+)NCBICelera
Cytogenetic Map20p12NCBI
GSTT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh372224,376,133 - 24,384,311 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,706,141 - 22,714,231 (-)NCBINCBI36hg18NCBI36
Build 342222,700,694 - 22,708,785NCBI
Celera228,176,027 - 8,184,162 (-)NCBI
Cytogenetic Map22q11.23NCBI
HuRef227,324,342 - 7,332,477 (-)NCBIHuRef
Gstt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,619,647 - 75,634,418 (-)NCBIGRCm39mm39
GRCm39 Ensembl1075,619,647 - 75,634,418 (-)Ensembl
GRCm381075,783,813 - 75,798,584 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,783,813 - 75,798,584 (-)EnsemblGRCm38mm10GRCm38
MGSCv371075,246,558 - 75,261,329 (-)NCBIGRCm37mm9NCBIm37
MGSCv361075,227,531 - 75,242,300 (-)NCBImm8
Celera1076,828,580 - 76,843,364 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.58NCBI

Position Markers
RH130749  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02013,816,320 - 13,816,505NCBIRnor6.0
Rnor_5.02016,006,301 - 16,006,486UniSTSRnor5.0
RGSC_v3.42013,604,377 - 13,604,562UniSTSRGSC3.4
Celera2014,365,076 - 14,365,261UniSTS
RH 3.4 Map20154.86UniSTS
Cytogenetic Map20p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124652101Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125653396Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20126305996Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20126305996Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20127357423Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20128375393Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20128375393Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20128375393Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20128375393Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20128375393Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20133300419Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20137550487Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20137550487Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20201865447018654Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20299970747999707Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20340211127968216Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20403911318872273Rat
4889857Pur27Proteinuria QTL 2712.20.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20403911318872273Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)20410895649108956Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20485547515050565Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20587544818739210Rat
1581577Pur15Proteinuria QTL 154.380.0002total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20865434118872273Rat
4889870Pur30Proteinuria QTL 30190.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20865434130991290Rat
631265Iresp1Immunoglobin response QTL18.3blood anti-double stranded DNA antibody amount (VT:0004762)serum anti-DNA antibody level (CMO:0001533)20965564214411641Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:149
Count of miRNA genes:114
Interacting mature miRNAs:120
Transcripts:ENSRNOT00000001669
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 28 20 10 20 27 34 10
Low 2 43 29 21 9 21 8 11 70 8 7 1 8
Below cutoff 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001669   ⟹   ENSRNOP00000001669
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2013,799,102 - 13,816,526 (+)Ensembl
RefSeq Acc Id: NM_053293   ⟹   NP_445745
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22012,856,680 - 12,873,586 (+)NCBI
Rnor_6.02013,799,102 - 13,816,527 (+)NCBI
Rnor_5.02015,989,083 - 16,006,508 (+)NCBI
RGSC_v3.42013,604,355 - 13,621,456 (-)RGD
Celera2014,348,088 - 14,365,283 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772859   ⟹   XP_008771081
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22012,856,930 - 12,873,580 (+)NCBI
Rnor_6.02013,799,394 - 13,816,521 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772860   ⟹   XP_008771082
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22012,856,963 - 12,873,580 (+)NCBI
Rnor_6.02013,799,399 - 13,816,521 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772861   ⟹   XP_008771083
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22012,870,795 - 12,873,580 (+)NCBI
Rnor_6.02013,813,552 - 13,816,521 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098441   ⟹   XP_038954369
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22012,856,678 - 12,873,580 (+)NCBI
RefSeq Acc Id: XM_039098442   ⟹   XP_038954370
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22012,856,613 - 12,871,278 (+)NCBI
RefSeq Acc Id: XM_039098443   ⟹   XP_038954371
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22012,861,800 - 12,873,580 (+)NCBI
RefSeq Acc Id: XM_039098444   ⟹   XP_038954372
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22012,870,416 - 12,873,580 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_445745   ⟸   NM_053293
- UniProtKB: Q01579 (UniProtKB/Swiss-Prot),   B6DYQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771082   ⟸   XM_008772860
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008771081   ⟸   XM_008772859
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008771083   ⟸   XM_008772861
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000001669   ⟸   ENSRNOT00000001669
RefSeq Acc Id: XP_038954370   ⟸   XM_039098442
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038954369   ⟸   XM_039098441
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038954371   ⟸   XM_039098443
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038954372   ⟸   XM_039098444
- Peptide Label: isoform X5
Protein Domains
GST C-terminal   GST N-terminal

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701534
Promoter ID:EPDNEW_R12058
Type:multiple initiation site
Name:Gstt1_1
Description:glutathione S-transferase theta 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02013,799,083 - 13,799,143EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2765 AgrOrtholog
Ensembl Genes ENSRNOG00000049771 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000001669 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001669 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7301492 IMAGE-MGC_LOAD
InterPro Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_C_Theta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_N_Theta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105379 IMAGE-MGC_LOAD
NCBI Gene 25260 ENTREZGENE
Pfam GST_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GSTT1 RGD
PhenoGen Gstt1 PhenoGen
PROSITE GST_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_NTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47616 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC206835
UniProt B6DYQ8 ENTREZGENE, UniProtKB/TrEMBL
  GSTT1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q2XTA7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Gstt1  glutathione S-transferase theta 1    glutathione S-transferase, theta 1  Name updated 1299863 APPROVED
2002-06-10 Gstt1  Glutathione S-transferase 1 (theta)      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein 244 amino acid residues 68795
gene_transcript transcript promoter region lacks both TATA and CAAT boxes 68795