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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2765
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gstt1
Name: glutathione S-transferase theta 1
Acc ID: CHEBI:24814
Term: indole-3-methanol
Definition: An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Chemical ID: MESH:C016517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstt1affects expressionEXP 6480464CTDindole-3-carbinol affects the expression of GSTT1 mRNAPMID:21396975
Gstt1increases expressionEXP 6480464CTDindole-3-carbinol results in increased expression of GSTT1 mRNA; indole-3-carbinol results in increased expression of GSTT1 proteinPMID:10413528 PMID:9794803
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