Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: GSTT1 (glutathione S-transferase theta 1) Homo sapiens
Symbol: GSTT1
Name: glutathione S-transferase theta 1
Description: The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutathione S-transferase theta-1; glutathione s-transferase, theta 1; glutathione transferase T1-1; GST class-theta-1
Related Pseudogenes: GSTTP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Annotation category: only annotated on alternate loci in reference assembly
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh372224,376,135 - 24,384,284 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,706,141 - 22,714,231 (-)NCBINCBI36hg18NCBI36
Build 342222,700,694 - 22,708,785NCBI
Celera228,176,027 - 8,184,162 (-)NCBI
Cytogenetic Map22q11.23NCBI
HuRef227,324,342 - 7,332,477 (-)NCBIHuRef

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GSTT1
Alliance Gene
Ensembl Gene
JBrowse: hg19
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736934
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.