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Gene: GSTT1 (glutathione S-transferase theta 1) Homo sapiens
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Symbol: GSTT1
Name: glutathione S-transferase theta 1
Description: The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutathione S-transferase theta-1; glutathione s-transferase, theta 1; glutathione transferase T1-1; GST class-theta-1
Orthologs:
Related Pseudogenes: GSTTP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Annotation category: only annotated on alternate loci in reference assembly
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh372224,376,135 - 24,384,284 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,706,141 - 22,714,231 (-)NCBINCBI36hg18NCBI36
Build 342222,700,694 - 22,708,785NCBI
Celera228,176,027 - 8,184,162 (-)NCBI
Cytogenetic Map22q11.23NCBI
HuRef227,324,342 - 7,332,477 (-)NCBIHuRef


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Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GSTT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736934
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.