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Gene: S100a8 (S100 calcium binding protein A8) Rattus norvegicus
Symbol: S100a8
Name: S100 calcium binding protein A8
RGD ID: 620265
Description: Predicted to have calcium ion binding activity and calcium-dependent protein binding activity. Involved in several processes, including autocrine signaling; response to ethanol; and response to lipopolysaccharide. Localizes to extracellular space. Biomarker of urinary bladder cancer. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A8 (S100 calcium binding protein A8); INTERACTS WITH (S)-colchicine; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calgranulin-A; migration inhibitory factor-related protein 8; MRP-8; Mrp8; p8; protein S100-A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A)
Homo sapiens (human) : S100A8 (S100 calcium binding protein A8)  HGNC  Alliance
Mus musculus (house mouse) : S100a8 (S100 calcium binding protein A8 (calgranulin A))  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : S100A8 (S100 calcium binding protein A8)
Canis lupus familiaris (dog) : S100A8 (S100 calcium binding protein A8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S100a8 (S100 calcium binding protein A8)
Sus scrofa (pig) : S100A8 (S100 calcium binding protein A8)
Chlorocebus sabaeus (African green monkey) : S100A8 (S100 calcium binding protein A8)
Heterocephalus glaber (naked mole-rat) : S100a8 (S100 calcium binding protein A8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02190,073,239 - 190,074,333 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2190,073,815 - 190,074,354 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02209,507,598 - 209,508,692 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,961,994 - 182,962,513 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12182,912,099 - 182,912,619 (+)NCBI
Celera2170,099,876 - 170,100,395 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on S100a8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620265
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.