(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of HK2 mRNA CTD PMID:17971868 (-)-epigallocatechin 3-gallate increases expression ISO RGD:733090 6480464 epigallocatechin gallate results in increased expression of HK2 mRNA CTD PMID:16084531 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:733090 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of HK2 mRNA CTD PMID:22079256 1,1-dichloroethene increases expression ISO RGD:735576 6480464 vinylidene chloride results in increased expression of HK2 mRNA CTD PMID:26682919 1,10-phenanthroline increases expression ISO RGD:733090 6480464 1, 10-phenanthroline results in increased expression of HK2 mRNA CTD PMID:19502547 1,2-dimethylhydrazine multiple interactions ISO RGD:735576 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HK2 mRNA CTD PMID:22206623 17alpha-ethynylestradiol multiple interactions ISO RGD:735576 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HK2 mRNA CTD PMID:17942748 17beta-estradiol decreases expression ISO RGD:733090 6480464 Estradiol results in decreased expression of HK2 mRNA CTD PMID:20106945 , PMID:21632981 17beta-estradiol multiple interactions ISO RGD:733090 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of HK2 mRNA CTD PMID:30165855 17beta-estradiol increases expression ISO RGD:733090 6480464 Estradiol results in increased expression of HK2 mRNA CTD PMID:23019147 , PMID:31614463 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:733090 6480464 Dihydrotestosterone results in increased expression of HK2 mRNA CTD PMID:29581250 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO RGD:733090 6480464 2 more ... CTD PMID:20394812 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:733090 6480464 2 more ... CTD PMID:19095052 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735576 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HK2 mRNA, Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA] CTD PMID:16054899 , PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of HK2 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of HK2 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735576 6480464 Tetrachlorodibenzodioxin results in increased expression of HK2 mRNA CTD PMID:17035482 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:735576 6480464 Tetrachlorodibenzodioxin affects the expression of HK2 mRNA CTD PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:733090 6480464 Tetrachlorodibenzodioxin results in increased expression of HK2 mRNA CTD PMID:20106945 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:733090 6480464 Endosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of HK2 mRNA] CTD PMID:26159488 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2-deoxy-D-glucose multiple interactions ISO RGD:733090 6480464 Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein] more ... CTD PMID:32619556 , PMID:34481905 2-ethoxyethanol increases expression EXP 6480464 2-ethoxyethanol results in increased expression of HK2 mRNA CTD PMID:19643169 2-hydroxypropanoic acid decreases expression ISO RGD:733090 6480464 Lactic Acid results in decreased expression of HK2 mRNA CTD PMID:30851411 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of HK2 mRNA CTD PMID:19643169 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:34256052 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 AHR gene mutant form inhibits the reaction [3 more ... CTD PMID:34256052 3-bromopyruvic acid decreases activity ISO RGD:733090 6480464 bromopyruvate results in decreased activity of HK2 protein CTD PMID:21548882 3-bromopyruvic acid decreases response to substance ISO RGD:735576 6480464 HK2 protein results in decreased susceptibility to bromopyruvate CTD PMID:28433571 3-bromopyruvic acid decreases expression ISO RGD:735576 6480464 bromopyruvate results in decreased expression of HK2 mRNA, bromopyruvate results in decreased expression of HK2 protein CTD PMID:28433571 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:735576 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA more ... CTD PMID:16054899 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:733090 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HK2 mRNA CTD PMID:28628672 3-methyladenine multiple interactions ISO RGD:733090 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein], 3-methyladenine inhibits the reaction [Potassium Dichromate results in increased expression of HK2 protein] CTD PMID:32569804 , PMID:34481905 4-chlorobiphenyl increases expression ISO RGD:733090 6480464 4-chlorobiphenyl metabolite results in increased expression of HK2 mRNA CTD PMID:25417049 4-phenylbutyric acid multiple interactions ISO RGD:733090 6480464 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of HK2 protein] CTD PMID:32569804 5-fluorouracil decreases expression ISO RGD:733090 6480464 Fluorouracil results in decreased expression of HK2 protein CTD PMID:16595493 5-fluorouracil affects response to substance ISO RGD:733090 6480464 HK2 protein affects the susceptibility to Fluorouracil CTD PMID:18772588 5-fluorouracil multiple interactions ISO RGD:733090 6480464 HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein] CTD PMID:18772588 acetamide increases expression EXP 6480464 acetamide results in increased expression of HK2 mRNA CTD PMID:31881176 acrolein increases expression EXP 6480464 Acrolein results in increased expression of HK2 mRNA, Acrolein results in increased expression of HK2 protein CTD PMID:35150775 acrylamide decreases expression ISO RGD:735576 6480464 Acrylamide results in decreased expression of HK2 mRNA CTD PMID:21319176 acrylamide decreases expression ISO RGD:733090 6480464 Acrylamide results in decreased expression of HK2 mRNA CTD PMID:32763439 aflatoxin B1 increases expression ISO RGD:733090 6480464 Aflatoxin B1 results in increased expression of HK2 mRNA CTD PMID:32234424 all-trans-retinoic acid decreases expression ISO RGD:733090 6480464 Tretinoin results in decreased expression of HK2 mRNA CTD PMID:23724009 all-trans-retinoic acid increases expression ISO RGD:733090 6480464 Tretinoin results in increased expression of HK2 mRNA CTD PMID:33167477 alpha-cyano-4-hydroxycinnamic acid decreases expression ISO RGD:733090 6480464 alpha-cyano-4-hydroxycinnamate results in decreased expression of HK2 mRNA, alpha-cyano-4-hydroxycinnamate results in decreased expression of HK2 protein CTD PMID:26384349 AP20187 multiple interactions ISO RGD:733090 6480464 [AP20187 results in increased activity of INSR protein mutant form] which results in decreased expression of HK2 mRNA CTD PMID:29330302 aristolochic acid decreases expression ISO RGD:733090 6480464 aristolochic acid I results in decreased expression of HK2 mRNA CTD PMID:33212167 arsane multiple interactions ISO RGD:733090 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of HK2 mRNA CTD PMID:32525701 arsenic atom multiple interactions ISO RGD:733090 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of HK2 mRNA CTD PMID:32525701 arsenite(3-) multiple interactions ISO RGD:733090 6480464 arsenite inhibits the reaction [G3BP1 protein binds to HK2 mRNA] CTD PMID:32406909 arsenous acid decreases activity ISO RGD:733090 6480464 Arsenic Trioxide results in decreased activity of HK2 protein CTD PMID:26598702 arsenous acid multiple interactions ISO RGD:733090 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HK2 protein] CTD PMID:26598702 Azaspiracid increases expression ISO RGD:733090 6480464 azaspiracid results in increased expression of HK2 mRNA CTD PMID:28939011 azathioprine decreases expression ISO RGD:733090 6480464 Azathioprine results in decreased expression of HK2 mRNA CTD PMID:22623647 benzo[a]pyrene affects expression ISO RGD:733090 6480464 Benzo(a)pyrene affects the expression of HK2 mRNA CTD PMID:20106945 benzo[a]pyrene decreases methylation ISO RGD:735576 6480464 Benzo(a)pyrene results in decreased methylation of HK2 3' UTR, Benzo(a)pyrene results in decreased methylation of HK2 exon CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:733090 6480464 Benzo(a)pyrene results in increased methylation of HK2 promoter CTD PMID:27901495 benzo[a]pyrene affects response to substance EXP 6480464 HK2 protein affects the susceptibility to Benzo(a)pyrene CTD PMID:22100782 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of HK2 mRNA CTD PMID:22100782 benzo[a]pyrene multiple interactions EXP 6480464 GSK3A protein affects the reaction [Benzo(a)pyrene results in increased expression of HK2 mRNA] more ... CTD PMID:22100782 benzo[a]pyrene decreases expression ISO RGD:733090 6480464 Benzo(a)pyrene results in decreased expression of HK2 mRNA CTD PMID:21632981 benzo[a]pyrene affects localization EXP 6480464 Benzo(a)pyrene affects the localization of HK2 protein CTD PMID:22100782 benzo[a]pyrene increases expression ISO RGD:735576 6480464 Benzo(a)pyrene results in increased expression of HK2 mRNA CTD PMID:21569818 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:733090 6480464 7 more ... CTD PMID:19150397 , PMID:20382639 benzoates decreases expression ISO RGD:733090 6480464 Benzoates analog results in decreased expression of HK2 mRNA CTD PMID:29472718 betulinic acid multiple interactions ISO RGD:733090 6480464 [VDAC1 protein results in decreased susceptibility to betulinic acid] which results in increased expression of HK2 protein CTD PMID:30136359 bicalutamide increases expression EXP 6480464 bicalutamide results in increased expression of HK2 protein CTD PMID:35151640 bifenthrin increases expression ISO RGD:735576 6480464 bifenthrin results in increased expression of HK2 mRNA CTD PMID:26071804 bis(2-ethylhexyl) phthalate increases expression ISO RGD:735576 6480464 Diethylhexyl Phthalate results in increased expression of HK2 mRNA CTD PMID:30284816 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of HK2 mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HK2 mRNA CTD PMID:30816183 more ... bisphenol A affects expression ISO RGD:733090 6480464 bisphenol A affects the expression of HK2 mRNA CTD PMID:30903817 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of HK2 gene CTD PMID:28505145 bisphenol A multiple interactions ISO RGD:733090 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HK2 mRNA CTD PMID:28628672 bisphenol F multiple interactions ISO RGD:735576 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of HK2 mRNA] more ... CTD PMID:34147605 bisphenol F increases expression ISO RGD:735576 6480464 bisphenol F results in increased expression of HK2 mRNA, bisphenol F results in increased expression of HK2 protein CTD PMID:34147605 butanal increases expression ISO RGD:733090 6480464 butyraldehyde results in increased expression of HK2 mRNA CTD PMID:26079696 cadmium atom increases expression ISO RGD:733090 6480464 Cadmium results in increased expression of HK2 mRNA CTD PMID:21694771 cadmium atom multiple interactions ISO RGD:735576 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein CTD PMID:34481905 cadmium atom multiple interactions ISO RGD:733090 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein] more ... CTD PMID:34481905 cadmium dichloride multiple interactions ISO RGD:735576 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein CTD PMID:34481905 cadmium dichloride multiple interactions ISO RGD:733090 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein] more ... CTD PMID:34481905 carbon nanotube increases expression ISO RGD:735576 6480464 Nanotubes more ... CTD PMID:25554681 CCCP multiple interactions ISO RGD:733090 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein] CTD PMID:34481905 celecoxib multiple interactions ISO RGD:735576 6480464 Celecoxib inhibits the reaction [Nickel results in increased expression of HK2 mRNA] CTD PMID:27452194 chlordecone increases expression ISO RGD:735576 6480464 Chlordecone results in increased expression of HK2 mRNA CTD PMID:33711761 chloroprene increases expression ISO RGD:735576 6480464 Chloroprene results in increased expression of HK2 mRNA CTD PMID:23125180 chloroquine multiple interactions ISO RGD:733090 6480464 [quizartinib co-treated with spautin-1 co-treated with Chloroquine] results in increased transport of and affects the localization of HK2 protein, LAMP2 protein alternative form affects the reaction [[quizartinib co-treated with spautin-1 co-treated with Chloroquine] results in increased transport of and affects the localization of HK2 protein] CTD PMID:30821613 choline multiple interactions ISO RGD:735576 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of HK2 mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of HK2 gene CTD PMID:20938992 chromium(6+) affects expression ISO RGD:735576 6480464 chromium hexavalent ion affects the expression of HK2 mRNA CTD PMID:28472532 chromium(6+) increases expression ISO RGD:733090 6480464 chromium hexavalent ion results in increased expression of HK2 mRNA, chromium hexavalent ion results in increased expression of HK2 protein CTD PMID:30690063 , PMID:32525551 clotrimazole affects localization ISO RGD:733090 6480464 Clotrimazole affects the localization of HK2 protein CTD PMID:20724915 clotrimazole decreases expression ISO RGD:733090 6480464 Clotrimazole results in decreased expression of HK2 mRNA CTD PMID:25863232 cobalt atom multiple interactions ISO RGD:733090 6480464 [tungsten carbide binds to Cobalt] which results in increased expression of HK2 mRNA CTD PMID:20105288 cobalt dichloride multiple interactions ISO RGD:733090 6480464 zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HK2 mRNA] CTD PMID:22202117 cobalt dichloride increases expression ISO RGD:733090 6480464 cobaltous chloride results in increased expression of HK2 mRNA CTD PMID:19502547 more ... cobalt(2+) sulfate increases expression ISO RGD:733090 6480464 cobalt sulfate results in increased expression of HK2 mRNA CTD PMID:19502547 copper(II) sulfate increases expression ISO RGD:733090 6480464 Copper Sulfate results in increased expression of HK2 mRNA CTD PMID:19549813 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of HK2 mRNA CTD PMID:27523638 cyclosporin A decreases expression ISO RGD:733090 6480464 Cyclosporine results in decreased expression of HK2 mRNA CTD PMID:25562108 cyclosporin A increases expression ISO RGD:733090 6480464 Cyclosporine results in increased expression of HK2 mRNA CTD PMID:27989131 desferrioxamine B multiple interactions ISO RGD:733090 6480464 Doxorubicin inhibits the reaction [Deferoxamine results in increased expression of HK2 protein] CTD PMID:34126102 desferrioxamine B increases expression ISO RGD:733090 6480464 Deferoxamine results in increased expression of HK2 protein CTD PMID:34126102 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of HK2 mRNA CTD PMID:14618091 dexamethasone multiple interactions ISO RGD:733090 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HK2 mRNA CTD PMID:28628672 dexamethasone multiple interactions ISO RGD:735576 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA more ... CTD PMID:16054899 , PMID:27452194 diarsenic trioxide decreases activity ISO RGD:733090 6480464 Arsenic Trioxide results in decreased activity of HK2 protein CTD PMID:26598702 diarsenic trioxide multiple interactions ISO RGD:733090 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to HK2 protein] CTD PMID:26598702 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of HK2 mRNA CTD PMID:21266533 dicrotophos increases expression ISO RGD:733090 6480464 dicrotophos results in increased expression of HK2 mRNA CTD PMID:28302478 dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of HK2 mRNA CTD PMID:23153324 dimercaprol multiple interactions ISO RGD:733090 6480464 Dimercaprol inhibits the reaction [4-aminophenylarsenoxide binds to HK2 protein] CTD PMID:26598702 dimethylarsinic acid multiple interactions ISO RGD:735576 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of HK2 mRNA CTD PMID:34876320 dimethylselenide multiple interactions ISO RGD:733090 6480464 [[Ozone results in increased oxidation of dimethylselenide] which results in decreased expression of HK2-DT mRNA] which results in decreased expression of HK2 mRNA CTD PMID:33656867 dinophysistoxin 1 increases expression ISO RGD:733090 6480464 dinophysistoxin 1 results in increased expression of HK2 mRNA CTD PMID:28939011 Diosbulbin B decreases expression ISO RGD:735576 6480464 diosbulbin B results in decreased expression of HK2 mRNA CTD PMID:32148032 dioxygen affects expression ISO RGD:735576 6480464 Oxygen deficiency affects the expression of HK2 mRNA CTD PMID:17193925 dioxygen increases expression ISO RGD:733090 6480464 Oxygen deficiency results in increased expression of HK2 mRNA, Oxygen deficiency results in increased expression of HK2 protein CTD PMID:19502547 more ... dorsomorphin multiple interactions ISO RGD:733090 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of HK2 mRNA CTD PMID:19915844 doxorubicin multiple interactions ISO RGD:733090 6480464 Doxorubicin inhibits the reaction [Deferoxamine results in increased expression of HK2 protein] CTD PMID:34126102 doxorubicin increases expression ISO RGD:733090 6480464 Doxorubicin results in increased expression of HK2 mRNA CTD PMID:29803840 doxorubicin decreases expression ISO RGD:735576 6480464 Doxorubicin results in decreased expression of HK2 mRNA, Doxorubicin results in decreased expression of HK2 protein CTD PMID:26873546 , PMID:29653124 doxorubicin decreases expression ISO RGD:733090 6480464 Doxorubicin results in decreased expression of HK2 mRNA, Doxorubicin results in decreased expression of HK2 protein CTD PMID:16595493 emodin increases expression ISO RGD:735576 6480464 Emodin results in increased expression of HK2 mRNA CTD PMID:21319176 endosulfan multiple interactions ISO RGD:733090 6480464 Endosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of HK2 mRNA] CTD PMID:26159488 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of HK2 mRNA CTD PMID:29391264 ethanol increases expression ISO RGD:735576 6480464 Ethanol results in increased expression of HK2 mRNA, Ethanol results in increased expression of HK2 protein CTD PMID:28962519 , PMID:30319688 ethyl methanesulfonate decreases expression ISO RGD:733090 6480464 Ethyl Methanesulfonate results in decreased expression of HK2 mRNA CTD PMID:23649840 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of HK2 mRNA CTD PMID:30307764 flutamide increases expression ISO RGD:735576 6480464 Flutamide analog results in increased expression of HK2 mRNA, Flutamide results in increased expression of HK2 mRNA CTD PMID:17702527 folic acid multiple interactions ISO RGD:735576 6480464 [1 more ... CTD PMID:20938992 , PMID:22206623 formaldehyde decreases expression ISO RGD:733090 6480464 Formaldehyde results in decreased expression of HK2 mRNA CTD PMID:23649840 fulvestrant multiple interactions ISO RGD:735576 6480464 Fulvestrant inhibits the reaction [bisphenol F results in increased expression of HK2 protein] CTD PMID:34147605 genistein increases expression ISO RGD:733090 6480464 Genistein results in increased expression of HK2 mRNA CTD PMID:23019147 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of HK2 mRNA CTD PMID:33387578 heptachlor increases expression EXP 6480464 Heptachlor results in increased expression of HK2 mRNA CTD PMID:23153324 hydrogen peroxide affects expression ISO RGD:733090 6480464 Hydrogen Peroxide affects the expression of HK2 mRNA CTD PMID:20044591 indometacin multiple interactions ISO RGD:735576 6480464 Indomethacin inhibits the reaction [Nickel results in increased expression of HK2 mRNA] CTD PMID:27452194 indometacin multiple interactions ISO RGD:733090 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HK2 mRNA CTD PMID:28628672 ionomycin increases expression EXP 6480464 Ionomycin results in increased expression of HK2 mRNA CTD PMID:17516843 irinotecan affects expression EXP 6480464 Irinotecan affects the expression of HK2 mRNA CTD PMID:20097248 isoprenaline decreases expression ISO RGD:735576 6480464 Isoproterenol results in decreased expression of HK2 mRNA CTD PMID:20003209 josamycin decreases response to substance ISO RGD:733090 6480464 HK2 protein results in decreased susceptibility to Josamycin CTD PMID:31915244 L-methionine multiple interactions ISO RGD:735576 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of HK2 mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of HK2 gene CTD PMID:20938992 lead(0) affects expression ISO RGD:733090 6480464 Lead affects the expression of HK2 mRNA CTD PMID:22313790 lead(2+) affects expression ISO RGD:733090 6480464 Lead affects the expression of HK2 mRNA CTD PMID:22313790 leflunomide increases expression ISO RGD:733090 6480464 leflunomide results in increased expression of HK2 mRNA CTD PMID:28988120 , PMID:29427785 leptomycin B multiple interactions ISO RGD:733090 6480464 [leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of HK2 mRNA CTD PMID:20803015 lipopolysaccharide decreases expression ISO RGD:733090 6480464 Lipopolysaccharides results in decreased expression of HK2 mRNA CTD PMID:21540303 LY294002 decreases expression ISO RGD:733090 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of HK2 protein CTD PMID:35122754 LY294002 multiple interactions ISO RGD:735576 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of HK2 mRNA], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol F results in increased expression of HK2 protein] CTD PMID:34147605 LY294002 multiple interactions ISO RGD:733090 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [fosbretabulin analog results in decreased expression of HK2 protein] CTD PMID:35122754 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of HK2 mRNA CTD PMID:16507785 methyl methanesulfonate decreases expression ISO RGD:733090 6480464 Methyl Methanesulfonate results in decreased expression of HK2 mRNA CTD PMID:23649840 methylarsonic acid multiple interactions ISO RGD:735576 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of HK2 mRNA CTD PMID:34876320 methylmercury chloride decreases expression ISO RGD:733090 6480464 methylmercuric chloride results in decreased expression of HK2 mRNA CTD PMID:23179753 , PMID:27188386 microcystin-LR increases expression ISO RGD:735576 6480464 cyanoginosin LR results in increased expression of HK2 mRNA CTD PMID:17654400 , PMID:25497113 mirex increases expression EXP 6480464 Mirex results in increased expression of HK2 mRNA CTD PMID:23153324 N-acetyl-beta-D-glucosamine increases expression ISO RGD:733090 6480464 Acetylglucosamine results in increased expression of HK2 mRNA CTD PMID:18047607 N-acetyl-D-glucosamine increases expression ISO RGD:733090 6480464 Acetylglucosamine results in increased expression of HK2 mRNA CTD PMID:18047607 N-acetyl-L-cysteine increases expression ISO RGD:733090 6480464 Acetylcysteine results in increased expression of HK2 mRNA CTD PMID:16084531 N-methyl-4-phenylpyridinium decreases expression ISO RGD:735576 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of HK2 mRNA CTD PMID:17475336 N-methyl-4-phenylpyridinium increases expression ISO RGD:733090 6480464 1-Methyl-4-phenylpyridinium results in increased expression of HK2 mRNA CTD PMID:24810058 nickel atom increases expression ISO RGD:733090 6480464 Nickel results in increased expression of HK2 mRNA CTD PMID:24768652 , PMID:25583101 nickel atom multiple interactions ISO RGD:735576 6480464 Celecoxib inhibits the reaction [Nickel results in increased expression of HK2 mRNA] more ... CTD PMID:27452194 nickel atom increases expression ISO RGD:735576 6480464 Nickel results in increased expression of HK2 mRNA CTD PMID:27452194 nickel dichloride multiple interactions ISO RGD:733090 6480464 2-amino-3-(4'-N, N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide inhibits the reaction [nickel chloride results in increased expression of HK2 mRNA] CTD PMID:33596451 nickel dichloride increases expression ISO RGD:735576 6480464 nickel chloride results in increased expression of HK2 mRNA CTD PMID:12426141 more ... nickel dichloride multiple interactions ISO RGD:735576 6480464 Dinoprostone promotes the reaction [nickel chloride results in increased expression of HK2 mRNA], HIF1A affects the reaction [nickel chloride results in increased expression of HK2 mRNA] CTD PMID:12426141 more ... nickel dichloride increases expression ISO RGD:733090 6480464 nickel chloride results in increased expression of HK2 mRNA, nickel chloride results in increased expression of HK2 protein CTD PMID:21455298 more ... nickel subsulfide affects expression ISO RGD:735576 6480464 nickel subsulfide affects the expression of HK2 mRNA CTD PMID:12729255 nickel sulfate decreases expression ISO RGD:733090 6480464 nickel sulfate results in decreased expression of HK2 mRNA CTD PMID:22714537 ochratoxin A increases expression ISO RGD:733090 6480464 ochratoxin A results in increased expression of HK2 protein CTD PMID:32835834 okadaic acid increases expression ISO RGD:733090 6480464 Okadaic Acid results in increased expression of HK2 mRNA CTD PMID:28939011 ozone multiple interactions ISO RGD:733090 6480464 [[Ozone results in increased oxidation of dimethylselenide] which results in decreased expression of HK2-DT mRNA] which results in decreased expression of HK2 mRNA CTD PMID:33656867 paracetamol affects expression ISO RGD:735576 6480464 Acetaminophen affects the expression of HK2 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of HK2 mRNA CTD PMID:33387578 pentanal increases expression ISO RGD:733090 6480464 pentanal results in increased expression of HK2 mRNA CTD PMID:26079696 perfluorooctane-1-sulfonic acid affects localization ISO RGD:735576 6480464 perfluorooctane sulfonic acid affects the localization of HK2 protein CTD PMID:28288859 perfluorooctanoic acid multiple interactions ISO RGD:735576 6480464 Dietary Fats, Unsaturated promotes the reaction [perfluorooctanoic acid results in increased expression of HK2 mRNA] CTD PMID:23626681 pirinixic acid decreases expression ISO RGD:735576 6480464 pirinixic acid results in decreased expression of HK2 mRNA CTD PMID:17426115 pirinixic acid increases expression ISO RGD:735576 6480464 pirinixic acid results in increased expression of HK2 mRNA CTD PMID:16985257 potassium chromate multiple interactions ISO RGD:733090 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of HK2 mRNA CTD PMID:22079256 potassium chromate increases expression ISO RGD:733090 6480464 potassium chromate(VI) results in increased expression of HK2 mRNA CTD PMID:22079256 , PMID:22714537 potassium dichromate multiple interactions ISO RGD:733090 6480464 3-methyladenine inhibits the reaction [Potassium Dichromate results in increased expression of HK2 protein] more ... CTD PMID:32569804 potassium dichromate increases expression ISO RGD:733090 6480464 Potassium Dichromate results in increased expression of HK2 protein CTD PMID:32569804 promethazine decreases expression EXP 6480464 Promethazine results in decreased expression of HK2 mRNA CTD PMID:28903497 propanal increases expression ISO RGD:733090 6480464 propionaldehyde results in increased expression of HK2 mRNA CTD PMID:26079696 prostaglandin E2 multiple interactions ISO RGD:735576 6480464 Dinoprostone promotes the reaction [nickel chloride results in increased expression of HK2 mRNA] CTD PMID:27452194 prostaglandin E2 increases expression ISO RGD:735576 6480464 Dinoprostone results in increased expression of HK2 mRNA CTD PMID:27452194 quercetin multiple interactions ISO RGD:733090 6480464 Quercetin inhibits the reaction [SP1 protein promotes the reaction [AR protein results in increased expression of HK2 mRNA]] CTD PMID:15661808 quercetin decreases expression ISO RGD:733090 6480464 Quercetin results in decreased expression of HK2 mRNA CTD PMID:21632981 quizartinib multiple interactions ISO RGD:733090 6480464 [quizartinib co-treated with spautin-1 co-treated with Chloroquine] results in increased transport of and affects the localization of HK2 protein, LAMP2 protein alternative form affects the reaction [[quizartinib co-treated with spautin-1 co-treated with Chloroquine] results in increased transport of and affects the localization of HK2 protein] CTD PMID:30821613 rac-lactic acid decreases expression ISO RGD:733090 6480464 Lactic Acid results in decreased expression of HK2 mRNA CTD PMID:30851411 radon atom increases expression ISO RGD:733090 6480464 Radon results in increased expression of HK2 protein CTD PMID:32198912 radon(0) increases expression ISO RGD:733090 6480464 Radon results in increased expression of HK2 protein CTD PMID:32198912 resveratrol decreases expression ISO RGD:733090 6480464 resveratrol results in decreased expression of HK2 mRNA CTD PMID:16979140 rotenone increases expression ISO RGD:735576 6480464 Rotenone results in increased expression of HK2 mRNA CTD PMID:17702527 rotenone increases expression ISO RGD:733090 6480464 Rotenone results in increased expression of HK2 mRNA CTD PMID:29955902 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of HK2 mRNA CTD PMID:28374803 roxadustat increases expression ISO RGD:733090 6480464 roxadustat results in increased expression of HK2 mRNA CTD PMID:33596451 SB 431542 multiple interactions ISO RGD:733090 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 serpentine asbestos increases expression ISO RGD:733090 6480464 Asbestos, Serpentine results in increased expression of HK2 mRNA CTD PMID:29523930 silicon dioxide affects expression ISO RGD:733090 6480464 Silicon Dioxide analog affects the expression of HK2 mRNA CTD PMID:25895662 silicon dioxide decreases expression ISO RGD:733090 6480464 Silicon Dioxide results in decreased expression of HK2 mRNA CTD PMID:22300531 , PMID:25351596 silver atom decreases expression ISO RGD:735576 6480464 Silver results in decreased expression of HK2 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:735576 6480464 Silver results in decreased expression of HK2 mRNA CTD PMID:27131904 sodium arsenate multiple interactions ISO RGD:733090 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of HK2 mRNA CTD PMID:32525701 sodium arsenate multiple interactions ISO RGD:735576 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of HK2 mRNA CTD PMID:34876320 sodium arsenite increases expression ISO RGD:733090 6480464 sodium arsenite results in increased expression of HK2 mRNA, sodium arsenite results in increased expression of HK2 protein CTD PMID:27287256 sodium arsenite multiple interactions ISO RGD:735576 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of HK2 mRNA CTD PMID:34876320 sodium arsenite multiple interactions ISO RGD:733090 6480464 HIF1A protein affects the reaction [sodium arsenite results in increased expression of HK2 protein] more ... CTD PMID:27287256 sodium dodecyl sulfate decreases expression ISO RGD:733090 6480464 Sodium Dodecyl Sulfate results in decreased expression of HK2 mRNA CTD PMID:31734321 Soman increases expression EXP 6480464 Soman results in increased expression of HK2 mRNA CTD PMID:19281266 sunitinib increases expression ISO RGD:733090 6480464 Sunitinib results in increased expression of HK2 mRNA CTD PMID:31533062 tacrolimus hydrate increases expression ISO RGD:735576 6480464 Tacrolimus results in increased expression of HK2 mRNA CTD PMID:29362864 tetrachloromethane affects expression ISO RGD:735576 6480464 Carbon Tetrachloride affects the expression of HK2 mRNA CTD PMID:17484886 thapsigargin increases expression ISO RGD:733090 6480464 Thapsigargin results in increased expression of HK2 mRNA CTD PMID:21694771 thapsigargin decreases expression ISO RGD:733090 6480464 Thapsigargin results in decreased expression of HK2 mRNA CTD PMID:22378314 thimerosal decreases expression ISO RGD:733090 6480464 Thimerosal results in decreased expression of HK2 mRNA CTD PMID:27188386 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of HK2 mRNA CTD PMID:28903497 , PMID:34492290 titanium dioxide decreases expression ISO RGD:735576 6480464 titanium dioxide results in decreased expression of HK2 mRNA CTD PMID:23557971 , PMID:29264374 tolfenamic acid multiple interactions ISO RGD:733090 6480464 tolfenamic acid affects the reaction [TGFB1 protein affects the expression of HK2 protein] CTD PMID:31381904 Tributyltin oxide increases expression ISO RGD:735576 6480464 bis(tri-n-butyltin)oxide results in increased expression of HK2 mRNA CTD PMID:18958704 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of HK2 mRNA CTD PMID:33387578 trichostatin A decreases expression ISO RGD:733090 6480464 trichostatin A results in decreased expression of HK2 mRNA CTD PMID:24935251 trichostatin A multiple interactions ISO RGD:733090 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HK2 mRNA CTD PMID:27188386 trichostatin A increases expression ISO RGD:733090 6480464 trichostatin A results in increased expression of HK2 mRNA CTD PMID:24935251 , PMID:26272509 Triptolide increases expression ISO RGD:735576 6480464 triptolide results in increased expression of HK2 mRNA CTD PMID:34087332 Triptolide decreases expression ISO RGD:735576 6480464 triptolide results in decreased expression of HK2 mRNA CTD PMID:34087332 troglitazone decreases expression ISO RGD:735576 6480464 troglitazone results in decreased expression of HK2 mRNA CTD PMID:12732648 Tungsten carbide multiple interactions ISO RGD:733090 6480464 [tungsten carbide binds to Cobalt] which results in increased expression of HK2 mRNA CTD PMID:20105288 tunicamycin increases expression ISO RGD:735576 6480464 Tunicamycin results in increased expression of HK2 mRNA CTD PMID:17127020 tunicamycin decreases expression ISO RGD:733090 6480464 Tunicamycin results in decreased expression of HK2 mRNA CTD PMID:22378314 urethane decreases expression ISO RGD:733090 6480464 Urethane results in decreased expression of HK2 mRNA CTD PMID:28818685 valproic acid increases expression ISO RGD:733090 6480464 Valproic Acid results in increased expression of HK2 mRNA CTD PMID:23179753 more ... valproic acid decreases expression ISO RGD:733090 6480464 Valproic Acid results in decreased expression of HK2 mRNA CTD PMID:23179753 , PMID:27188386 valproic acid increases methylation ISO RGD:733090 6480464 Valproic Acid results in increased methylation of HK2 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:733090 6480464 Valproic Acid affects the expression of HK2 mRNA CTD PMID:25979313 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of HK2 mRNA CTD PMID:23034163 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of HK2 gene CTD PMID:31682807 vorinostat multiple interactions ISO RGD:733090 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HK2 mRNA CTD PMID:27188386 vorinostat increases expression ISO RGD:733090 6480464 vorinostat results in increased expression of HK2 mRNA CTD PMID:26272509 vorinostat decreases expression ISO RGD:733090 6480464 vorinostat results in decreased expression of HK2 mRNA CTD PMID:27188386 Yessotoxin increases expression ISO RGD:733090 6480464 yessotoxin analog results in increased expression of HK2 mRNA CTD PMID:30679557 zearalenone increases expression ISO RGD:733090 6480464 Zearalenone results in increased expression of HK2 mRNA CTD PMID:32119988 zinc dichloride multiple interactions ISO RGD:733090 6480464 zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HK2 mRNA] CTD PMID:22202117
