Acot9 (acyl-CoA thioesterase 9) - Rat Genome Database

Name: Acot9
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Acot9 (acyl-CoA thioesterase 9) Rattus norvegicus

Analyze

Symbol:

Acot9

Name:

acyl-CoA thioesterase 9

RGD ID:

1359188

Description:

Predicted to enable acetyl-CoA hydrolase activity and palmitoyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process; long-chain fatty acid metabolic process; and short-chain fatty acid metabolic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human ACOT9 (acyl-CoA thioesterase 9); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Acate2; acyl-Coenzyme A thioesterase 2, mitochondrial; acyl-coenzyme A thioesterase 9, mitochondrial; LOC302640; similar to acyl-CoA thioesterase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACOT9 (acyl-CoA thioesterase 9)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Acot9 (acyl-CoA thioesterase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Acot9 (acyl-CoA thioesterase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACOT9 (acyl-CoA thioesterase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACOT9 (acyl-CoA thioesterase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Acot9 (acyl-CoA thioesterase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACOT9 (acyl-CoA thioesterase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACOT9 (acyl-CoA thioesterase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Acot9 (acyl-CoA thioesterase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ACOT9 (acyl-CoA thioesterase 9)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Acot10 (acyl-CoA thioesterase 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Acot9 (acyl-CoA thioesterase 9)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	acot9.1 (acyl-CoA thioesterase 9, tandem duplicate 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	acot9.2 (acyl-CoA thioesterase 9, tandem duplicate 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG13771	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1635	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1638	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1774	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F57F4.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T07D3.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T22B7.7	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	acot9	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	40,073,197 - 40,123,573 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	40,064,810 - 40,123,559 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	41,332,153 - 41,371,197 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	44,799,449 - 44,838,500 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	42,484,036 - 42,523,088 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	43,543,069 - 43,592,200 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	43,543,070 - 43,592,200 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	43,846,064 - 43,895,821 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	61,548,318 - 61,600,120 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	61,601,787 - 61,653,589 (-)	NCBI
Celera	X	40,701,964 - 40,751,523 (-)	NCBI		Celera
Cytogenetic Map	X	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-dexrazoxane (ISO)

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

2-acetamidofluorene (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

acetamide (EXP)

aconitine (EXP)

aristolochic acid A (EXP)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

Benzo[k]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

butanal (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

choline (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cyproconazole (EXP)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP,ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

epoxiconazole (EXP,ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

furan (EXP)

genistein (EXP)

gentamycin (EXP)

heptanal (ISO)

hexanal (ISO)

indole-3-methanol (EXP)

ivermectin (ISO)

L-methionine (ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

nonanal (ISO)

obeticholic acid (ISO)

octanal (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

prochloraz (EXP)

progesterone (ISO)

propanal (ISO)

resveratrol (ISO)

sodium dichromate (EXP)

Soman (EXP)

streptozocin (ISO)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

tetrahydropalmatine (ISO)

thioacetamide (EXP)

Triptolide (ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acyl-CoA metabolic process (IBA,ISO)

long-chain fatty acid metabolic process (ISO)

short-chain fatty acid metabolic process (ISO)

Cellular Component

mitochondrial matrix (ISO)

mitochondrion (IBA,ISO)

Molecular Function

acetyl-CoA hydrolase activity (ISO)

acyl-CoA hydrolase activity (IBA,ISO)

carboxylic ester hydrolase activity (IEA)

palmitoyl-CoA hydrolase activity (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:10383425	PMID:16103133	PMID:18614015

Genomics

Comparative Map Data

Acot9
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	40,073,197 - 40,123,573 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	40,064,810 - 40,123,559 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	41,332,153 - 41,371,197 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	44,799,449 - 44,838,500 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	42,484,036 - 42,523,088 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	43,543,069 - 43,592,200 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	43,543,070 - 43,592,200 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	43,846,064 - 43,895,821 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	61,548,318 - 61,600,120 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	61,601,787 - 61,653,589 (-)	NCBI
Celera	X	40,701,964 - 40,751,523 (-)	NCBI		Celera
Cytogenetic Map	X	q21	NCBI

ACOT9
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	23,701,055 - 23,743,276 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	23,701,055 - 23,766,475 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	23,719,172 - 23,761,393 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	23,631,698 - 23,671,328 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	X	27,842,554 - 27,882,190 (-)	NCBI		Celera
Cytogenetic Map	X	p22.11	NCBI
HuRef	X	21,460,810 - 21,501,317 (-)	NCBI		HuRef
CHM1_1	X	23,752,695 - 23,792,269 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	23,284,668 - 23,326,884 (-)	NCBI		T2T-CHM13v2.0

Acot9
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	154,045,439 - 154,080,650 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	154,045,439 - 154,080,650 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	155,262,443 - 155,297,654 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	155,262,443 - 155,297,654 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	151,697,043 - 151,732,050 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	150,603,226 - 150,638,364 (+)	NCBI		MGSCv36	mm8
Celera	X	138,566,044 - 138,601,000 (+)	NCBI		Celera
Cytogenetic Map	X	F3	NCBI
cM Map	X	72.38	NCBI

Acot9
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955509	4,143,586 - 4,167,128 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955509	4,143,246 - 4,167,129 (-)	NCBI	ChiLan1.0	ChiLan1.0

ACOT9
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	X	25,503,513 - 25,547,923 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	16,300,116 - 16,365,713 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	23,678,071 - 23,717,092 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	23,676,669 - 23,717,092 (-)	Ensembl	panpan1.1		panPan2

ACOT9
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	19,395,763 - 19,460,945 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	19,395,762 - 19,551,198 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	X	19,350,059 - 19,415,885 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	19,342,343 - 19,374,457 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	19,389,633 - 19,455,007 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	19,422,682 - 19,488,508 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	19,479,032 - 19,544,221 (-)	NCBI		UU_Cfam_GSD_1.0

Acot9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	12,323,397 - 12,397,793 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936624	795,237 - 836,571 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936624	795,272 - 834,441 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACOT9
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	19,834,614 - 19,864,660 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	19,835,674 - 19,864,570 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	21,205,864 - 21,234,787 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACOT9
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	22,152,651 - 22,190,536 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	22,151,384 - 22,190,505 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	24,048,616 - 24,087,263 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acot9
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624897	125,348 - 155,621 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624897	125,348 - 155,557 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Acot9
99 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	35
Interacting mature miRNAs:	38
Transcripts:	ENSRNOT00000005033
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1	43491017	Rat
1298071	Edpm12	Estrogen-dependent pituitary mass QTL 12	3.2		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	X	2927898	47927898	Rat
10755455	Coatc13	Coat color QTL 13		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	4406000	49406000	Rat
631666	Iddm5	Insulin dependent diabetes mellitus QTL 5			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	4494549	49494549	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
71116	Niddm16	Non-insulin dependent diabetes mellitus QTL 16	7.81		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	15297802	60297802	Rat
1598873	Memor2	Memory QTL 2	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	X	20990947	41052531	Rat
2290375	Gluco34	Glucose level QTL 34	2.75		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	X	20990947	41203591	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	34	18	19	18	8	11	74	35	34	11	8
Low			23	23		23					7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC085822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000005033 ⟹ ENSRNOP00000005033

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	40,073,205 - 40,123,559 (-)	Ensembl
Rnor_6.0 Ensembl	X	43,543,070 - 43,592,200 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111580 ⟹ ENSRNOP00000089191

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	40,073,198 - 40,116,798 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000113538 ⟹ ENSRNOP00000091656

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	40,064,810 - 40,123,559 (-)	Ensembl

RefSeq Acc Id:

NM_001013960 ⟹ NP_001013982

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	40,073,197 - 40,123,465 (-)	NCBI
Rnor_6.0	X	43,543,069 - 43,592,200 (-)	NCBI
Rnor_5.0	X	43,846,064 - 43,895,821 (-)	NCBI
RGSC_v3.4	X	61,548,318 - 61,600,120 (-)	RGD
Celera	X	40,701,964 - 40,751,523 (-)	RGD

Sequence:

show sequence

CTCACGCTCACGCTCTTCTGTCTCCCGTTTGTCTCTCTATACGGGAGGACGTTGGTTGTCCTCC
CGTGGGTAGGCAGTGGAGTGCCATGAAGCGGGCAGCGATGCGTCTTTGGACCTTGAACAAGGGG
CTTCTTACACATGGCAGAGGACTGGCTTACGGATCTGAAAACAAAATATGTAAACCTTTACACA
TACAGGAAGTTCGAAATAAGCTGCGGGAGATCGTAGGCGTATCCACAATCTGGAGAGACCATGT
AAAAGCAATGGAGGAAAGGAAGTTACTTCATAATTTTTTGGCTACATCACAGAAAGCCCTACCA
CCGAGGAAAATGAAGGACAGTTACATTGAAGTCCTCCTGCCTTTGGGTTCTGACCCTGATCTAC
GAGACAAATATTTGACTGTTCAAAATACAGTGAGATTTGGCAGGATTCTTGAGGACCTTGATAG
CTTAGGAGTTCTTGTTTGCTACATGCACAACCAAAATCATTCTACCAAGATGTCTCCATTATCA
ATCGTTACAGTCCTGGTGGACAAGATTGATATGTGTAAATACAGCTTAAGCCCTGAACAGGACA
TTAAGTTCACTGGCCATGTTAGCTGGGTTGGAAAGACTTCCATGGAAGTGAAGATGAAAATGTT
TCAGATGCACAGTGATGATAAATTTTGGCCTGTTTTGGATGCAACCTTTGTAATGGTGGCTCGA
GATTCTGAAAATAAAGGGCCTGCATTTGTAAATCCACTTGTTCCTGAAAATAAAGAAGAAGAAG
AACTTATTACACAAGGAGAATTGAACAAGAGCCGAAGGATTGCTTTTAGCACCACTTCATTACT
GAAAGTAGCTCCTAATTCTGAGGAGAGGAATGTCATACATGAACTGTTTCTTAACACACTGGAT
CCAAAGACTATAAGTTTTCAGAGTCGAATTTTGCCTCCTAAGGCAGTGTGGATGGAGGATACAA
AACTCAAGAGCTTGGATATTTGTCACCCTCAGGAGCGAAACATTTTCAATAGGATTTTTGGTGG
TTTTCTTATGAGAAAAGCATATGAACTTGCATGGGCTACAGCTTGTAGTTTTGGTGGTTCCCGG
CCATATGTGGTAACAGTAGATGATATCATGTTTCAGAAACCTGTTGAAGTTGGCTCATTGCTCT
TTCTTTCTTCACAGGTATGCTTCACCCAGGACAATTACATTCAAGTCAGAGTCCATAGTGAAGT
GGCCTCTCTTGACAGTCGTGAGCATATGACCACCAATGTCTTTCATTTTACATTCATGTCAGAA
AAAGAAGTACCCTTGATTTTCCCCAAAACATATGGAGAGTCCATGTTGTATTTAGATGGACAGC
GGCATTTCAAGTCCATGAGTACCCCAGTGATCTTGAAAAAGAACTACACTGTGGAGCCCTAGGA
AAAATCTCACTTGTTGCAAATCAGCACTTCAGGCACAGTGACATAGTGCCTAATAAAGGCATGC
TGAGAAATATTGATGTTCACATTGCTTTTTTATCTTCCATAGAGGGGACTATATTCAACTTTTA
GAATGATCAGAAAAGCAGAACAAGTGACTGAATGGGGCTAAGGGGTGAAAGAATGATTAAACAA
TAAAACCTTTTATAGTAATGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039099644 ⟹ XP_038955572

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	40,073,197 - 40,123,573 (-)	NCBI

RefSeq Acc Id:

XM_039099645 ⟹ XP_038955573

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	40,073,197 - 40,123,573 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013982	(Get FASTA)	NCBI Sequence Viewer
	XP_038955572	(Get FASTA)	NCBI Sequence Viewer
	XP_038955573	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85822	(Get FASTA)	NCBI Sequence Viewer
	EDL96100	(Get FASTA)	NCBI Sequence Viewer
	EDL96101	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013982 ⟸ NM_001013960

- UniProtKB:

Q5U2X8 (UniProtKB/TrEMBL), F7ETS0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKRAAMRLWTLNKGLLTHGRGLAYGSENKICKPLHIQEVRNKLREIVGVSTIWRDHVKAMEERK
LLHNFLATSQKALPPRKMKDSYIEVLLPLGSDPDLRDKYLTVQNTVRFGRILEDLDSLGVLVCY
MHNQNHSTKMSPLSIVTVLVDKIDMCKYSLSPEQDIKFTGHVSWVGKTSMEVKMKMFQMHSDDK
FWPVLDATFVMVARDSENKGPAFVNPLVPENKEEEELITQGELNKSRRIAFSTTSLLKVAPNSE
ERNVIHELFLNTLDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNIFNRIFGGFLMRKAY
ELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQDNYIQVRVHSEVASLDSRE
HMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVILKKNYTVEP

hide sequence

RefSeq Acc Id:

ENSRNOP00000005033 ⟸ ENSRNOT00000005033

RefSeq Acc Id:	XP_038955573 ⟸ XM_039099645
- Peptide Label:	isoform X1
- UniProtKB:	A6IPR3 (UniProtKB/TrEMBL), F7ETS0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038955572 ⟸ XM_039099644
- Peptide Label:	isoform X1
- UniProtKB:	A6IPR3 (UniProtKB/TrEMBL), F7ETS0 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000089191 ⟸ ENSRNOT00000111580

RefSeq Acc Id:

ENSRNOP00000091656 ⟸ ENSRNOT00000113538

Protein Domains

HotDog ACOT-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5U2X8-F1-model_v2	AlphaFold	Q5U2X8	1-439	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359188	AgrOrtholog
BioCyc Gene	G2FUF-2442	BioCyc
BioCyc Pathway	PWY-5148 [acyl-CoA hydrolysis]	BioCyc
	PWY-5972 [stearate biosynthesis I (animals)]	BioCyc
	PWY-5996 [oleate biosynthesis II (animals and fungi)]	BioCyc
	PWY-8042 [acylceramide biosynthesis]	BioCyc
	PWY3O-1801 [palmitoleate biosynthesis IV (fungi and animals)]	BioCyc
Ensembl Genes	ENSRNOG00000003782	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000005033	ENTREZGENE
	ENSRNOP00000005033.5	UniProtKB/TrEMBL
	ENSRNOP00000089191.1	UniProtKB/TrEMBL
	ENSRNOP00000091656.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005033	ENTREZGENE
	ENSRNOT00000005033.6	UniProtKB/TrEMBL
	ENSRNOT00000111580.1	UniProtKB/TrEMBL
	ENSRNOT00000113538.1	UniProtKB/TrEMBL
Gene3D-CATH	Hotdog Thioesterase	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7126662	IMAGE-MGC_LOAD
InterPro	HOTDOG_ACOT	UniProtKB/TrEMBL
	HotDog_dom	UniProtKB/TrEMBL
KEGG Report	rno:302640	UniProtKB/TrEMBL
MGC_CLONE	MGC:94122	IMAGE-MGC_LOAD
NCBI Gene	302640	ENTREZGENE
PANTHER	ACYL-COA THIOESTERASE	UniProtKB/TrEMBL
	ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL	UniProtKB/TrEMBL
PhenoGen	Acot9	PhenoGen
PROSITE	HOTDOG_ACOT	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54637	UniProtKB/TrEMBL
UniProt	A0A8I6A6Q0_RAT	UniProtKB/TrEMBL
	A0A8I6AFW7_RAT	UniProtKB/TrEMBL
	A6IPR3	ENTREZGENE, UniProtKB/TrEMBL
	F7ETS0	ENTREZGENE, UniProtKB/TrEMBL
	Q5U2X8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-05	Acot9	acyl-CoA thioesterase 9	LOC302640	similar to acyl-CoA thioesterase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-29	LOC302640	similar to acyl-CoA thioesterase			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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