Acer2 (alkaline ceramidase 2) - Rat Genome Database

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Gene: Acer2 (alkaline ceramidase 2) Rattus norvegicus
Analyze
Symbol: Acer2
Name: alkaline ceramidase 2
RGD ID: 1304629
Description: Predicted to enable dihydroceramidase activity. Predicted to be involved in several processes, including negative regulation of cell adhesion; regulation of protein metabolic process; and sphingolipid metabolic process. Predicted to be located in Golgi membrane. Orthologous to human ACER2 (alkaline ceramidase 2); PARTICIPATES IN sphingolipid metabolic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Asah3l; LOC313339; N-acylsphingosine amidohydrolase 3-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25101,391,830 - 101,442,615 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5101,391,885 - 101,442,614 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5103,772,875 - 103,817,891 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05105,563,430 - 105,608,446 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05105,596,792 - 105,641,922 (+)NCBIRnor_WKY
Rnor_6.05105,230,540 - 105,279,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,230,580 - 105,279,731 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05109,217,448 - 109,266,600 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45106,185,779 - 106,237,588 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15106,185,877 - 106,412,446 (+)NCBI
Celera5101,644,752 - 101,692,910 (-)NCBICelera
Cytogenetic Map5q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
carmustine  (EXP)
chlordecone  (ISO)
chloroethene  (ISO)
chloroprene  (EXP)
choline  (ISO)
cisplatin  (ISO)
crocidolite asbestos  (ISO)
cypermethrin  (ISO)
decabromodiphenyl ether  (EXP)
dioxygen  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
epoxiconazole  (ISO)
fipronil  (EXP)
folic acid  (ISO)
furan  (EXP)
glafenine  (EXP)
indole-3-methanol  (EXP)
isoprenaline  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP)
mercaptopurine  (EXP)
methotrexate  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
purine-6-thiol  (EXP)
rac-lactic acid  (ISO)
resveratrol  (EXP)
rotenone  (EXP)
sirolimus  (ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tebuconazole  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
tioguanine  (EXP)
titanium dioxide  (EXP,ISO)
toluene  (EXP)
topotecan  (EXP)
tremolite asbestos  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
urethane  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:16940153   PMID:18945876   PMID:20089856   PMID:20207939   PMID:20628055   PMID:26943039   PMID:28294157   PMID:29229990   PMID:29401619  


Genomics

Comparative Map Data
Acer2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25101,391,830 - 101,442,615 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5101,391,885 - 101,442,614 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5103,772,875 - 103,817,891 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05105,563,430 - 105,608,446 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05105,596,792 - 105,641,922 (+)NCBIRnor_WKY
Rnor_6.05105,230,540 - 105,279,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,230,580 - 105,279,731 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05109,217,448 - 109,266,600 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45106,185,779 - 106,237,588 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15106,185,877 - 106,412,446 (+)NCBI
Celera5101,644,752 - 101,692,910 (-)NCBICelera
Cytogenetic Map5q32NCBI
ACER2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38919,409,009 - 19,452,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl919,409,009 - 19,452,505 (+)EnsemblGRCh38hg38GRCh38
GRCh37919,409,007 - 19,452,503 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36919,398,925 - 19,442,500 (+)NCBINCBI36Build 36hg18NCBI36
Celera919,335,075 - 19,378,570 (+)NCBICelera
Cytogenetic Map9p22.1NCBI
HuRef919,370,525 - 19,414,024 (+)NCBIHuRef
CHM1_1919,408,778 - 19,452,327 (+)NCBICHM1_1
T2T-CHM13v2.0919,421,828 - 19,465,242 (+)NCBIT2T-CHM13v2.0
Acer2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39486,792,585 - 86,853,059 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl486,792,633 - 86,853,059 (+)EnsemblGRCm39 Ensembl
GRCm38486,874,348 - 86,932,524 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl486,874,396 - 86,934,822 (+)EnsemblGRCm38mm10GRCm38
MGSCv37486,520,318 - 86,566,785 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36486,345,695 - 86,392,106 (+)NCBIMGSCv36mm8
Celera485,395,108 - 85,439,689 (+)NCBICelera
Cytogenetic Map4C4NCBI
Acer2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543421,786,856 - 21,810,648 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543421,786,857 - 21,810,648 (+)NCBIChiLan1.0ChiLan1.0
ACER2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan19105,098,921 - 105,145,396 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0919,216,891 - 19,262,477 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1919,706,716 - 19,751,057 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl919,709,402 - 19,750,896 (+)Ensemblpanpan1.1panPan2
ACER2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11139,190,873 - 39,223,590 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1139,190,115 - 39,219,776 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1137,848,571 - 37,881,294 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01140,124,209 - 40,156,941 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1140,124,252 - 40,156,909 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11138,816,668 - 38,849,382 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01138,614,132 - 38,646,861 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01139,248,101 - 39,280,836 (+)NCBIUU_Cfam_GSD_1.0
Acer2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947153,619,937 - 153,659,729 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366521,289,382 - 1,329,409 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049366521,289,445 - 1,329,236 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACER2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,386,791 - 203,414,972 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11203,387,669 - 203,415,018 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,035,770 - 227,065,826 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACER2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11260,286,802 - 60,323,359 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1260,283,174 - 60,321,817 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603848,397,984 - 48,467,119 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acer2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473623,363,983 - 23,411,100 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473623,363,806 - 23,556,247 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Acer2
285 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:533
Count of miRNA genes:260
Interacting mature miRNAs:352
Transcripts:ENSRNOT00000010056
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599485997103690167Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599753548113061097Rat

Markers in Region
RH129365  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,442,257 - 101,442,473 (+)MAPPERmRatBN7.2
Rnor_6.05105,279,375 - 105,279,590NCBIRnor6.0
Rnor_5.05109,266,243 - 109,266,458UniSTSRnor5.0
RGSC_v3.45106,237,232 - 106,237,447UniSTSRGSC3.4
Celera5101,644,893 - 101,645,108UniSTS
RH 3.4 Map5739.7UniSTS
Cytogenetic Map5q32UniSTS
RH137105  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,442,267 - 101,442,468 (+)MAPPERmRatBN7.2
Rnor_6.05105,279,385 - 105,279,585NCBIRnor6.0
Rnor_5.05109,266,253 - 109,266,453UniSTSRnor5.0
RGSC_v3.45106,237,242 - 106,237,442UniSTSRGSC3.4
Celera5101,644,898 - 101,645,098UniSTS
RH 3.4 Map5739.3UniSTS
Cytogenetic Map5q32UniSTS
RH142072  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,439,761 - 101,439,970 (+)MAPPERmRatBN7.2
Rnor_6.05105,276,879 - 105,277,087NCBIRnor6.0
Rnor_5.05109,263,747 - 109,263,955UniSTSRnor5.0
RGSC_v3.45106,234,737 - 106,234,945UniSTSRGSC3.4
Celera5101,647,395 - 101,647,603UniSTS
RH 3.4 Map5737.5UniSTS
Cytogenetic Map5q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 9 4 4 31 5 11
Low 3 35 48 37 19 37 8 11 74 4 36 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010056   ⟹   ENSRNOP00000010056
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5101,391,885 - 101,442,614 (+)Ensembl
Rnor_6.0 Ensembl5105,230,580 - 105,279,731 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115639   ⟹   ENSRNOP00000094342
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5101,391,885 - 101,442,614 (+)Ensembl
RefSeq Acc Id: NM_001107943   ⟹   NP_001101413
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,391,885 - 101,442,614 (+)NCBI
Rnor_6.05105,230,580 - 105,279,731 (+)NCBI
Rnor_5.05109,217,448 - 109,266,600 (+)NCBI
RGSC_v3.45106,185,779 - 106,237,588 (+)RGD
Celera5101,644,752 - 101,692,910 (-)RGD
Sequence:
RefSeq Acc Id: XM_006238363   ⟹   XP_006238425
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,391,836 - 101,442,615 (+)NCBI
Rnor_6.05105,230,540 - 105,279,732 (+)NCBI
Rnor_5.05109,217,448 - 109,266,600 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109889   ⟹   XP_038965817
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,391,830 - 101,436,511 (+)NCBI
RefSeq Acc Id: XM_039109891   ⟹   XP_038965819
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,392,672 - 101,442,615 (+)NCBI
RefSeq Acc Id: XM_039109892   ⟹   XP_038965820
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,391,832 - 101,438,320 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001101413   ⟸   NM_001107943
- UniProtKB: D3ZNW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238425   ⟸   XM_006238363
- Peptide Label: isoform X1
- UniProtKB: D3ZNW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010056   ⟸   ENSRNOT00000010056
RefSeq Acc Id: XP_038965817   ⟸   XM_039109889
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965820   ⟸   XM_039109892
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038965819   ⟸   XM_039109891
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000094342   ⟸   ENSRNOT00000115639

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZNW4-F1-model_v2 AlphaFold D3ZNW4 1-275 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693826
Promoter ID:EPDNEW_R4351
Type:multiple initiation site
Name:Acer2_1
Description:alkaline ceramidase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05105,230,616 - 105,230,676EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304629 AgrOrtholog
BioCyc Gene G2FUF-40837 BioCyc
Ensembl Genes ENSRNOG00000007637 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000010056 ENTREZGENE
  ENSRNOP00000010056.4 UniProtKB/TrEMBL
  ENSRNOP00000094342.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010056 ENTREZGENE
  ENSRNOT00000010056.7 UniProtKB/TrEMBL
  ENSRNOT00000115639.1 UniProtKB/TrEMBL
InterPro Ceramidase UniProtKB/TrEMBL
KEGG Report rno:313339 UniProtKB/TrEMBL
NCBI Gene 313339 ENTREZGENE
PANTHER ALKALINE CERAMIDASE 2 UniProtKB/TrEMBL
  PTHR46139 UniProtKB/TrEMBL
Pfam aPHC UniProtKB/TrEMBL
PhenoGen Acer2 PhenoGen
UniProt A0A8I6B090_RAT UniProtKB/TrEMBL
  D3ZNW4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-01-05 Acer2  alkaline ceramidase 2  Asah3l  N-acylsphingosine amidohydrolase 3-like   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Asah3l  N-acylsphingosine amidohydrolase 3-like   Asah3l_predicted  N-acylsphingosine amidohydrolase 3-like (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Asah3l_predicted  N-acylsphingosine amidohydrolase 3-like (predicted)      Symbol and Name status set to approved 70820 APPROVED