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Gene: Ahcy (adenosylhomocysteinase) Rattus norvegicus
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Symbol: Ahcy
Name: adenosylhomocysteinase
Description: Exhibits adenosylhomocysteinase activity; identical protein binding activity; and nucleotide binding activity. Involved in several processes, including S-adenosylhomocysteine catabolic process; chronic inflammatory response to antigenic stimulus; and circadian sleep/wake cycle. Localizes to the cytosol; neuron projection; and nucleus. Used to study hyperhomocysteinemia and pyridoxine deficiency anemia. Human ortholog(s) of this gene implicated in hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Orthologous to human AHCY (adenosylhomocysteinase); PARTICIPATES IN methionine cycle/metabolic pathway; choline metabolic pathway; glycine N-methyltransferase deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adoHcyase; S-adenosyl-L-homocysteine hydrolase; S-adenosylhomocysteine hydrolase
Orthologs:
Homo sapiens (human) : AHCY (adenosylhomocysteinase)  HGNC  Alliance
Mus musculus (house mouse) : Ahcy (S-adenosylhomocysteine hydrolase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ahcy (adenosylhomocysteinase)
Pan paniscus (bonobo/pygmy chimpanzee) : AHCY (adenosylhomocysteinase)
Canis lupus familiaris (dog) : AHCY (adenosylhomocysteinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ahcy (adenosylhomocysteinase)
Sus scrofa (pig) : AHCY (adenosylhomocysteinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03150,587,833 - 150,603,057 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3150,587,833 - 150,603,082 (-)Ensembl
Rnor_5.03156,957,240 - 156,972,464 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43145,544,834 - 145,560,058 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13145,450,455 - 145,465,680 (-)NCBI
Celera3142,299,485 - 142,314,709 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ahcy
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69260
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.