Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ntf3 (neurotrophin 3) Rattus norvegicus
Symbol: Ntf3
Name: neurotrophin 3
Description: Exhibits nerve growth factor binding activity. Involved in modulation of chemical synaptic transmission; myelination; and positive regulation of glial cell differentiation. Predicted to localize to several cellular components, including axon; dendrite; and synaptic vesicle. Human ortholog(s) of this gene implicated in Alzheimer's disease and asthma. Orthologous to human NTF3 (neurotrophin 3); PARTICIPATES IN mitogen activated protein kinase signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH (+)-pilocarpine; (R)-adrenaline; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HDNF; nerve growth factor 2; neurotrophic factor; neurotrophin-3; neurotrophin-3 (HDNF/NT-3); NGF-2; NT-3
Homo sapiens (human) : NTF3 (neurotrophin 3)  HGNC  Alliance
Mus musculus (house mouse) : Ntf3 (neurotrophin 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ntf3 (neurotrophin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NTF3 (neurotrophin 3)
Canis lupus familiaris (dog) : NTF3 (neurotrophin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ntf3 (neurotrophin 3)
Sus scrofa (pig) : NTF3 (neurotrophin 3)
Chlorocebus sabaeus (African green monkey) : NTF3 (neurotrophin 3)
Heterocephalus glaber (naked mole-rat) : Ntf3 (neurotrophin 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04158,636,883 - 158,705,886 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4158,636,884 - 158,705,886 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04225,638,801 - 225,707,719 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44162,435,781 - 162,506,961 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14162,680,717 - 162,751,897 (-)NCBI
Celera4147,640,921 - 147,710,546 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ntf3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619728
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.