(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2A1 mRNA] CTD PMID:31150632 (1->4)-beta-D-glucan multiple interactions ISO RGD:1621331 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CYP2A22 mRNA CTD PMID:36331819 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of CYP2A1 mRNA CTD PMID:22934830 (S)-nicotine increases hydroxylation EXP 6480464 CYP2A6 protein results in increased hydroxylation of Nicotine CTD PMID:12919726 (S)-nicotine multiple interactions ISO RGD:1352512 6480464 Nicotine inhibits the reaction [[CYP2A13 protein results in increased metabolism of N'-nitrosonornicotine] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone], Nicotine inhibits the reaction [CYP2A13 protein results in increased susceptibility to Aflatoxin B1] CTD PMID:22743290 , PMID:27567546 (S)-nicotine decreases activity ISO RGD:1352512 6480464 Nicotine results in decreased activity of CYP2A13 protein CTD PMID:27567546 (S)-nicotine increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of Nicotine CTD PMID:22743290 1,3,5-trinitro-1,3,5-triazinane increases expression EXP 6480464 cyclonite results in increased expression of CYP2A1 mRNA CTD PMID:25559034 1-benzylpiperazine decreases expression EXP 6480464 N-benzylpiperazine results in decreased expression of CYP2A1 mRNA CTD PMID:26821219 1-naphthol increases abundance ISO RGD:1352512 6480464 CYP2A13 protein results in increased abundance of 1-naphthol CTD PMID:27137136 1-naphthol multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased oxidation of naphthalene] which results in increased abundance of 1-naphthol CTD PMID:27137136 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP2A1 mRNA CTD PMID:30723492 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of CYP2A1 mRNA CTD PMID:16079270 17beta-estradiol 3-benzoate decreases expression EXP 6480464 estradiol 3-benzoate results in decreased expression of CYP2A1 protein CTD PMID:24752506 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2A1 mRNA CTD PMID:16054898 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1352512 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP2A13 mRNA CTD PMID:26159488 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1621331 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2A22 mRNA CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1621331 6480464 Tetrachlorodibenzodioxin affects the expression of CYP2A22 mRNA CTD PMID:26377647 , PMID:28922406 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of CYP2A1 mRNA CTD PMID:21346803 2-acetamidofluorene increases expression ISO RGD:1621331 6480464 2-Acetylaminofluorene results in increased expression of CYP2A22 mRNA CTD PMID:21607683 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:19692669 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of CYP2A1 mRNA CTD PMID:11323195 more ... 3-methyleneindolenine multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased metabolism of Skatole] which results in increased chemical synthesis of 3-methyleneindolenine CTD PMID:20187624 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of CYP2A1 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of CYP2A1 mRNA CTD PMID:30723492 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one affects metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:12920169 , PMID:17717079 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:17717079 more ... 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases hydroxylation ISO RGD:1352512 6480464 CYP2A13 protein results in increased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone, CYP2A13 results in increased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:17922361 , PMID:21473878 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases activity ISO RGD:1352512 6480464 CYP2A13 results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:21473878 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein SNP results in decreased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:14633739 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases hydroxylation ISO RGD:1352512 6480464 CYP2A13 gene polymorphism results in decreased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:17922361 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone more ... CTD PMID:14633739 more ... 4-oxo-4-(pyridin-3-yl)butanal multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] which results in increased abundance of 4-oxo-4-(3-pyridinebutanal), [CYP2A13 protein results in increased metabolism of N'-nitrosonornicotine] which results in increased abundance of 4-oxo-4-(3-pyridinebutanal) CTD PMID:27567546 4-oxo-4-(pyridin-3-yl)butanal increases abundance ISO RGD:1352512 6480464 CYP2A13 protein results in increased abundance of 4-oxo-4-(3-pyridinebutanal) CTD PMID:27567546 5-Hydroxyflavone increases oxidation ISO RGD:1352512 6480464 CYP2A13 protein results in increased oxidation of 5-hydroxyflavone CTD PMID:30964977 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of CYP2A1 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of CYP2A1 mRNA CTD PMID:19483382 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of CYP2A1 mRNA CTD PMID:22504374 9-phenanthrol multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol CTD PMID:27137136 9-phenanthrol increases abundance ISO RGD:1352512 6480464 CYP2A13 protein results in increased abundance of 9-phenanthrol CTD PMID:27137136 acenaphthene multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased oxidation of acenaphthene] which results in increased chemical synthesis of acenaphthene-1-ol CTD PMID:25642975 acenaphthene increases oxidation ISO RGD:1352512 6480464 CYP2A13 protein results in increased oxidation of acenaphthene CTD PMID:25642975 acenaphthylene increases oxidation ISO RGD:1352512 6480464 CYP2A13 protein results in increased oxidation of acenaphthylene, CYP2A13 protein results in increased oxidation of acenaphthylene metabolite CTD PMID:25642975 acetophenones increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of Acetophenones CTD PMID:18669584 acetophenones multiple interactions ISO RGD:1352512 6480464 CYP2A13 gene polymorphism inhibits the reaction [CYP2A13 protein results in increased metabolism of Acetophenones] CTD PMID:18669584 aflatoxin B1 decreases methylation ISO RGD:1352512 6480464 Aflatoxin B1 results in decreased methylation of CYP2A13 gene CTD PMID:27153756 aflatoxin B1 increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of Aflatoxin B1 CTD PMID:22743290 , PMID:26084420 aflatoxin B1 multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein co-treated with Aflatoxin B1] results in decreased expression of MIR1271 mRNA more ... CTD PMID:16917071 more ... aflatoxin B1 increases response to substance ISO RGD:1352512 6480464 CYP2A13 protein results in increased susceptibility to Aflatoxin B1 CTD PMID:22743290 , PMID:26084420 Aflatoxin G1 increases activity ISO RGD:1352512 6480464 CYP2A13 protein results in increased activity of aflatoxin G1 CTD PMID:23907605 Aflatoxin G1 affects response to substance ISO RGD:1352512 6480464 CYP2A13 protein affects the susceptibility to aflatoxin G1 CTD PMID:23907605 alendronic acid affects expression EXP 6480464 Alendronate affects the expression of CYP2A1 mRNA CTD PMID:16079270 all-trans-retinoic acid increases expression ISO RGD:1352512 6480464 Tretinoin results in increased expression of CYP2A13 mRNA CTD PMID:21376804 alpha-hexachlorocyclohexane multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP2A1 protein CTD PMID:16246485 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of CYP2A1 mRNA CTD PMID:18355885 , PMID:19483382 amitriptyline affects expression EXP 6480464 Amitriptyline affects the expression of CYP2A1 mRNA CTD PMID:18355885 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CYP2A1 mRNA CTD PMID:16483693 amodiaquine increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of Amodiaquine CTD PMID:31629065 amodiaquine multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine CTD PMID:31629065 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2A1 mRNA CTD PMID:8471063 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CYP2A1 mRNA, Chlorodiphenyl (54% Chlorine) results in increased expression of CYP2A1 protein CTD PMID:11323195 , PMID:8471063 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of CYP2A1 mRNA CTD PMID:19483382 benzene decreases expression EXP 6480464 Benzene results in decreased expression of CYP2A1, Benzene results in decreased expression of CYP2A1 protein CTD PMID:8517779 , PMID:9010585 benzene increases expression EXP 6480464 Benzene results in increased expression of CYP2A1 protein CTD PMID:8620572 benzo[a]pyrene increases methylation ISO RGD:1352512 6480464 Benzo(a)pyrene results in increased methylation of CYP2A13 3' UTR, Benzo(a)pyrene results in increased methylation of CYP2A13 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:1352512 6480464 Benzo(a)pyrene results in decreased expression of CYP2A13 mRNA CTD PMID:32234424 beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of CYP2A1 mRNA CTD PMID:19118567 beta-naphthoflavone increases expression ISO RGD:1352512 6480464 beta-Naphthoflavone results in increased expression of CYP2A13 mRNA CTD PMID:22258563 bexarotene multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in increased expression of CYP2A1 mRNA CTD PMID:17630414 biphenyl affects binding ISO RGD:1352512 6480464 diphenyl binds to CYP2A13 protein CTD PMID:27137136 biphenyl increases oxidation ISO RGD:1352512 6480464 CYP2A13 protein results in increased oxidation of diphenyl CTD PMID:27137136 biphenyl-4-amine multiple interactions ISO RGD:1352512 6480464 CYP2A13 protein results in increased hydroxylation of and results in increased activity of 4-biphenylamine CTD PMID:16988941 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of CYP2A1 mRNA CTD PMID:25031359 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1621331 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A22 mRNA CTD PMID:33484791 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CYP2A1 protein CTD PMID:24752506 bisphenol A increases expression ISO RGD:1621331 6480464 bisphenol A results in increased expression of CYP2A22 mRNA CTD PMID:30245210 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CYP2A1 mRNA CTD PMID:30903817 carbon nanotube decreases expression ISO RGD:1621331 6480464 Nanotubes, Carbon results in decreased expression of CYP2A22 mRNA CTD PMID:25620056 carbon nanotube affects expression ISO RGD:1621331 6480464 Nanotubes, Carbon analog affects the expression of CYP2A22 mRNA CTD PMID:25620056 chenodeoxycholic acid decreases activity EXP 6480464 Chenodeoxycholic Acid results in decreased activity of CYP2A1 protein CTD PMID:8889968 chlorohydrocarbon multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of CYP2A1 mRNA CTD PMID:30744511 cholic acid decreases activity EXP 6480464 Cholic Acid results in decreased activity of CYP2A1 protein CTD PMID:8889968 chrysin increases oxidation ISO RGD:1352512 6480464 CYP2A13 protein results in increased oxidation of chrysin CTD PMID:30964977 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of CYP2A1 mRNA CTD PMID:19483382 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of CYP2A1 mRNA CTD PMID:11328961 clomipramine affects expression EXP 6480464 Clomipramine affects the expression of CYP2A1 mRNA CTD PMID:18355885 coumarin increases hydroxylation ISO RGD:1352512 6480464 CYP2A13 protein results in increased hydroxylation of coumarin CTD PMID:17922361 coumarin increases hydroxylation EXP 6480464 CYP2A6 protein results in increased hydroxylation of coumarin CTD PMID:12919726 coumarin decreases hydroxylation ISO RGD:1352512 6480464 CYP2A13 gene polymorphism results in decreased hydroxylation of coumarin CTD PMID:17922361 cyhalothrin increases activity EXP 6480464 cyhalothrin results in increased activity of CYP2A1 protein CTD PMID:29727961 cyhalothrin increases expression EXP 6480464 cyhalothrin results in increased expression of CYP2A1 mRNA CTD PMID:29727961 cylindrospermopsin decreases expression ISO RGD:1352512 6480464 cylindrospermopsin results in decreased expression of CYP2A13 mRNA CTD PMID:23726867 DDT increases expression EXP 6480464 DDT results in increased expression of CYP2A1 mRNA CTD PMID:29477483 deoxycholic acid decreases activity EXP 6480464 Deoxycholic Acid results in decreased activity of CYP2A1 protein CTD PMID:8889968 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of CYP2A1 mRNA CTD PMID:15102944 dichloroacetic acid increases expression ISO RGD:1621331 6480464 Dichloroacetic Acid results in increased expression of CYP2A22 mRNA CTD PMID:28962523 endosulfan multiple interactions ISO RGD:1352512 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP2A13 mRNA CTD PMID:26159488 ethanol increases expression EXP 6480464 Ethanol results in increased expression of CYP2A1 mRNA CTD PMID:15353170 farnesol increases activity EXP 6480464 Farnesol results in increased activity of CYP2A1 protein CTD PMID:15840382 fipronil increases expression EXP 6480464 fipronil results in increased expression of CYP2A1 mRNA CTD PMID:23962444 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of CYP2A1 mRNA CTD PMID:18035473 flutamide increases expression EXP 6480464 Flutamide results in increased expression of CYP2A1 mRNA CTD PMID:24136188 Furafylline decreases activity EXP 6480464 furafylline results in decreased activity of CYP2A1 protein CTD PMID:15879494 gamma-hexachlorocyclohexane increases activity EXP 6480464 Hexachlorocyclohexane results in increased activity of CYP2A1 protein CTD PMID:3569844 genistein multiple interactions EXP 6480464 [Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of CYP2A1 mRNA CTD PMID:25031359 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of CYP2A1 mRNA CTD PMID:24136188 helenalin increases oxidation ISO RGD:1352512 6480464 CYP2A13 protein results in increased oxidation of helenalin CTD PMID:34989853 helenalin decreases activity ISO RGD:1352512 6480464 helenalin results in decreased activity of CYP2A13 protein CTD PMID:34989853 hexamethylphosphoric triamide increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of Hempa CTD PMID:18669584 hexamethylphosphoric triamide multiple interactions ISO RGD:1352512 6480464 CYP2A13 gene polymorphism inhibits the reaction [CYP2A13 protein results in increased metabolism of Hempa] CTD PMID:18669584 imipramine affects expression EXP 6480464 Imipramine affects the expression of CYP2A1 mRNA CTD PMID:18355885 inulin multiple interactions ISO RGD:1621331 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of CYP2A22 mRNA CTD PMID:36331819 ketoconazole affects expression EXP 6480464 Ketoconazole affects the expression of CYP2A1 mRNA CTD PMID:18355885 ketoconazole decreases activity EXP 6480464 Ketoconazole results in decreased activity of CYP2A1 protein CTD PMID:15879494 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of CYP2A1 protein CTD PMID:7986207 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of CYP2A1 mRNA CTD PMID:19483382 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of CYP2A1 mRNA CTD PMID:24136188 lipopolysaccharide decreases expression ISO RGD:1352512 6480464 Lipopolysaccharides results in decreased expression of CYP2A13 mRNA, Lipopolysaccharides results in decreased expression of CYP2A13 protein CTD PMID:23884085 lipopolysaccharide multiple interactions ISO RGD:1352512 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CYP2A13 mRNA] CTD PMID:23884085 lithocholic acid decreases activity EXP 6480464 Lithocholic Acid results in decreased activity of CYP2A1 protein CTD PMID:8889968 m-xylene affects activity EXP 6480464 3-xylene affects the activity of CYP2A1 protein CTD PMID:15204773 methimazole increases expression EXP 6480464 Methimazole results in increased expression of CYP2A1 mRNA CTD PMID:22504374 methoxsalen decreases activity EXP 6480464 Methoxsalen results in decreased activity of CYP2A1 protein CTD PMID:12814958 methoxsalen multiple interactions ISO RGD:1352512 6480464 [Methoxsalen results in decreased activity of CYP2A13 protein] which results in decreased susceptibility to Skatole more ... CTD PMID:17671098 more ... methyl tert-butyl ether increases hydroxylation EXP 6480464 CYP2A6 protein results in increased hydroxylation of methyl tert-butyl ether CTD PMID:12919726 methylisothiazolinone decreases expression ISO RGD:1352512 6480464 2-methyl-4-isothiazolin-3-one results in decreased expression of CYP2A13 mRNA CTD PMID:31629900 methylmercury chloride multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of CYP2A1 mRNA CTD PMID:30744511 metyrapone multiple interactions ISO RGD:1352512 6480464 Metyrapone inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:18669584 miconazole multiple interactions ISO RGD:1352512 6480464 Miconazole inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:18669584 monosodium L-glutamate multiple interactions EXP 6480464 Sodium Glutamate results in increased expression of and results in increased activity of CYP2A1 protein CTD PMID:7476908 N'-Nitrosoanabasine multiple interactions ISO RGD:1352512 6480464 N'-nitrosoanabasine inhibits the reaction [[CYP2A13 protein results in increased metabolism of N'-nitrosonornicotine] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone] CTD PMID:27567546 N'-Nitrosoanabasine decreases activity ISO RGD:1352512 6480464 N'-nitrosoanabasine results in decreased activity of CYP2A13 protein CTD PMID:27567546 N'-Nitrosoanatabine multiple interactions ISO RGD:1352512 6480464 N'-nitrosoanatabine inhibits the reaction [[CYP2A13 protein results in increased metabolism of N'-nitrosonornicotine] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone] CTD PMID:27567546 N'-Nitrosoanatabine decreases activity ISO RGD:1352512 6480464 N'-nitrosoanatabine results in decreased activity of CYP2A13 protein CTD PMID:27567546 N'-Nitrosonornicotine increases hydroxylation ISO RGD:1352512 6480464 CYP2A13 protein results in increased hydroxylation of N'-nitrosonornicotine CTD PMID:17922361 N'-Nitrosonornicotine multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased metabolism of N'-nitrosonornicotine] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone more ... CTD PMID:27567546 N'-Nitrosonornicotine increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of N'-nitrosonornicotine CTD PMID:27567546 N,N-diethyl-m-toluamide increases expression ISO RGD:1352512 6480464 DEET results in increased expression of CYP2A13 mRNA CTD PMID:27091632 N,N-dimethylaniline increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of N, N-dimethylaniline CTD PMID:18669584 N,N-dimethylaniline multiple interactions ISO RGD:1352512 6480464 CYP2A13 gene polymorphism inhibits the reaction [CYP2A13 protein results in increased metabolism of N, N-dimethylaniline] CTD PMID:18669584 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP2A1 protein CTD PMID:16246485 N-nitrosodiethylamine increases expression ISO RGD:1621331 6480464 Diethylnitrosamine results in increased expression of CYP2A22 mRNA CTD PMID:21607683 N-nitrosodimethylamine increases hydroxylation EXP 6480464 CYP2A6 protein results in increased hydroxylation of Dimethylnitrosamine CTD PMID:12919726 N-Nitrosoguvacoline increases activity ISO RGD:1352512 6480464 CYP2A13 protein results in increased activity of N-nitrosoguvacoline CTD PMID:15725615 N-Nitrosopyrrolidine decreases expression ISO RGD:1352512 6480464 N-Nitrosopyrrolidine results in decreased expression of CYP2A13 mRNA CTD PMID:32234424 NADP zwitterion multiple interactions ISO RGD:1352512 6480464 [NADP co-treated with CYP2A13 protein] results in increased oxidation of 2-ethynylnaphthalene more ... CTD PMID:27137136 NADP(+) multiple interactions ISO RGD:1352512 6480464 [NADP co-treated with CYP2A13 protein] results in increased oxidation of 2-ethynylnaphthalene more ... CTD PMID:27137136 naphthalene increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of naphthalene CTD PMID:28599267 naphthalene affects binding ISO RGD:1352512 6480464 naphthalene binds to CYP2A13 protein CTD PMID:27137136 naphthalene multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased oxidation of naphthalene] which results in increased abundance of 1-naphthol more ... CTD PMID:27137136 , PMID:28599267 naphthalene increases oxidation ISO RGD:1352512 6480464 CYP2A13 protein results in increased oxidation of naphthalene CTD PMID:27137136 nicotine increases expression EXP 6480464 Nicotine results in increased expression of CYP2A1 mRNA CTD PMID:22934830 nicotine increases hydroxylation EXP 6480464 CYP2A6 protein results in increased hydroxylation of Nicotine CTD PMID:12919726 nicotine multiple interactions ISO RGD:1352512 6480464 Nicotine inhibits the reaction [[CYP2A13 protein results in increased metabolism of N'-nitrosonornicotine] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone], Nicotine inhibits the reaction [CYP2A13 protein results in increased susceptibility to Aflatoxin B1] CTD PMID:22743290 , PMID:27567546 nicotine increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of Nicotine CTD PMID:22743290 nicotine decreases activity ISO RGD:1352512 6480464 Nicotine results in decreased activity of CYP2A13 protein CTD PMID:27567546 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of CYP2A1 mRNA CTD PMID:24136188 O-methyleugenol decreases expression ISO RGD:1352512 6480464 methyleugenol results in decreased expression of CYP2A13 mRNA CTD PMID:32234424 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of CYP2A1 mRNA CTD PMID:19483382 organoselenium compound multiple interactions ISO RGD:1352512 6480464 Organoselenium Compounds binds to and results in decreased activity of CYP2A13 protein CTD PMID:21732699 oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of CYP2A1 mRNA CTD PMID:23439660 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1621331 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CYP2A22 mRNA more ... CTD PMID:36331819 phenanthrene increases oxidation ISO RGD:1352512 6480464 CYP2A13 protein results in increased oxidation of phenanthrene CTD PMID:27137136 phenanthrene affects binding ISO RGD:1352512 6480464 phenanthrene binds to CYP2A13 protein CTD PMID:27137136 phenanthrene multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol CTD PMID:27137136 phenanthrenes affects binding ISO RGD:1352512 6480464 Phenanthrenes analog binds to CYP2A13 protein CTD PMID:27137136 phenanthrenes multiple interactions ISO RGD:1352512 6480464 [NADP co-treated with CYP2A13 protein] results in increased oxidation of Phenanthrenes analog CTD PMID:27137136 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CYP2A1 mRNA CTD PMID:15596064 phenobarbital decreases expression ISO RGD:1621331 6480464 Phenobarbital results in decreased expression of CYP2A22 protein CTD PMID:35881160 phenobarbital increases expression ISO RGD:1352512 6480464 Phenobarbital results in increased expression of CYP2A13 mRNA CTD PMID:22258563 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of CYP2A1 mRNA CTD PMID:19483382 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of CYP2A1 mRNA CTD PMID:15596064 pyrrolidine dithiocarbamate multiple interactions ISO RGD:1352512 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CYP2A13 mRNA] CTD PMID:23884085 quinomethionate affects expression ISO RGD:1352512 6480464 quinomethionate affects the expression of CYP2A13 mRNA CTD PMID:15387888 quinomethionate increases expression ISO RGD:1352512 6480464 quinomethionate results in increased expression of CYP2A13 mRNA CTD PMID:18214805 raloxifene affects expression EXP 6480464 Raloxifene Hydrochloride affects the expression of CYP2A1 mRNA CTD PMID:16079270 resveratrol multiple interactions ISO RGD:1352512 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of CYP2A13 mRNA CTD PMID:23557933 rifampicin increases expression EXP 6480464 Rifampin results in increased expression of CYP2A1 mRNA CTD PMID:19118567 rifampicin decreases expression ISO RGD:1352512 6480464 Rifampin results in decreased expression of CYP2A13 mRNA CTD PMID:22258563 rifampicin increases expression ISO RGD:1352512 6480464 Rifampin results in increased expression of CYP2A13 mRNA CTD PMID:22258563 semicarbazide multiple interactions EXP 6480464 [carbamylhydrazine results in decreased activity of CYP2A1 protein] which results in decreased abundance of Testosterone metabolite, [carbamylhydrazine results in increased activity of CYP2A1 protein] which results in increased abundance of Testosterone metabolite CTD PMID:19788891 semicarbazide increases activity EXP 6480464 carbamylhydrazine results in increased activity of CYP2A1 protein CTD PMID:19788891 senecionine increases expression ISO RGD:1352512 6480464 senecionine results in increased expression of CYP2A13 mRNA CTD PMID:26100227 skatole multiple interactions ISO RGD:1352512 6480464 [CYP2A13 protein results in increased metabolism of Skatole] which results in increased chemical synthesis of 3-methyleneindolenine more ... CTD PMID:20187624 , PMID:20795680 skatole increases metabolic processing ISO RGD:1352512 6480464 CYP2A13 protein results in increased metabolism of Skatole CTD PMID:20187624 sodium arsenite decreases expression ISO RGD:1352512 6480464 sodium arsenite results in decreased expression of CYP2A13 mRNA CTD PMID:34032870 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of CYP2A1 mRNA CTD PMID:25993096 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of CYP2A1 mRNA CTD PMID:25905778 streptozocin multiple interactions ISO RGD:1621331 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A22 mRNA CTD PMID:33484791 tamoxifen multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in increased expression of CYP2A1 mRNA CTD PMID:17630414 taurocholic acid decreases activity EXP 6480464 Taurocholic Acid results in decreased activity of CYP2A1 protein CTD PMID:8889968 testosterone affects metabolic processing EXP 6480464 CYP2A1 protein affects the metabolism of Testosterone CTD PMID:15879494 testosterone multiple interactions EXP 6480464 [carbamylhydrazine results in decreased activity of CYP2A1 protein] which results in decreased abundance of Testosterone metabolite, [carbamylhydrazine results in increased activity of CYP2A1 protein] which results in increased abundance of Testosterone metabolite CTD PMID:19788891 testosterone enanthate decreases expression EXP 6480464 testosterone enanthate results in decreased expression of CYP2A1 protein CTD PMID:8573203 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of CYP2A1 mRNA, Carbon Tetrachloride results in decreased expression of CYP2A1 protein CTD PMID:17606319 , PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2A1 mRNA] CTD PMID:31150632 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of CYP2A1 mRNA CTD PMID:19483382 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of CYP2A1 mRNA CTD PMID:34492290 toluene increases expression EXP 6480464 Toluene results in increased expression of CYP2A1 protein CTD PMID:8620572 tranylcypromine multiple interactions ISO RGD:1352512 6480464 Tranylcypromine inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:18669584 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of CYP2A1 mRNA CTD PMID:19448997 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of CYP2A1 protein CTD PMID:8620572 Triptolide multiple interactions ISO RGD:1621331 6480464 TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP2A1 mRNA] CTD PMID:32987112 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of CYP2A1 protein CTD PMID:7986207
