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Gene: Cyp2a1 (cytochrome P450, family 2, subfamily a, polypeptide 1) Rattus norvegicus
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Symbol: Cyp2a1
Name: cytochrome P450, family 2, subfamily a, polypeptide 1
Description: Exhibits steroid hydroxylase activity. Involved in coumarin metabolic process. Localizes to the intracellular membrane-bounded organelle. Orthologous to human CYP2A7 (cytochrome P450 family 2 subfamily A member 7); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; caffeine metabolic pathway; retinol metabolic pathway; INTERACTS WITH (2-trans,6-trans)-farnesol; (S)-nicotine; 1,3,5-trinitro-1,3,5-triazinane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CYPIIA1; cytochrome P450 2A1; cytochrome P450 IIA1 (hepatic steroid hydroxylase IIA1); cytochrome P450 IIA1 (hepatic steroid hydroxylase IIA1) gene; cytochrome P450-UT-F; P450-UT-F; RATCYP2A1; Shdl; Shdl_mapped; steroid hormones 7-alpha-hydroxylase; steroid hydroxylase, hepatic; steroid hydroxylase, hepatic (mapped); testosterone 7-alpha-hydroxylase
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0183,711,223 - 83,725,222 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0184,925,733 - 84,938,423 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,006,828 - 82,020,282 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1182,084,938 - 82,098,390 (+)NCBI
Celera176,649,089 - 76,662,287 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cyp2a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2463
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.