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Gene: Mgst1 (microsomal glutathione S-transferase 1) Rattus norvegicus
Symbol: Mgst1
Name: microsomal glutathione S-transferase 1
Description: Exhibits glutathione binding activity; glutathione transferase activity; and identical protein binding activity. Involved in several processes, including Leydig cell differentiation; response to lipopolysaccharide; and response to organonitrogen compound. Localizes to several cellular components, including endoplasmic reticulum; mitochondrion; and peroxisomal membrane. Orthologous to human MGST1 (microsomal glutathione S-transferase 1); PARTICIPATES IN glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; (S)-amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC72699; microsomal GST-1; microsomal GST-I
Homo sapiens (human) : MGST1 (microsomal glutathione S-transferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mgst1 (microsomal glutathione S-transferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mgst1 (microsomal glutathione S-transferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MGST1 (microsomal glutathione S-transferase 1)
Canis lupus familiaris (dog) : MGST1 (microsomal glutathione S-transferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mgst1 (microsomal glutathione S-transferase 1)
Sus scrofa (pig) : MGST1 (microsomal glutathione S-transferase 1)
Chlorocebus sabaeus (African green monkey) : MGST1 (microsomal glutathione S-transferase 1)
Heterocephalus glaber (naked mole-rat) : Mgst1 (microsomal glutathione S-transferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04172,119,382 - 172,134,609 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4172,119,331 - 172,134,607 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04236,372,225 - 236,387,452 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44175,248,654 - 175,263,881 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14175,493,783 - 175,509,005 (+)NCBI
Celera4159,602,240 - 159,617,460 (+)NCBICelera
Cytogenetic Map4q44NCBI
RH 3.4 Map41032.9RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mgst1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70927
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.