Sult2a1 (sulfotransferase family 2A member 1) - Rat Genome Database
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Gene: Sult2a1 (sulfotransferase family 2A member 1) Rattus norvegicus
Analyze
Symbol: Sult2a1
Name: sulfotransferase family 2A member 1
RGD ID: 621337
Description: Exhibits 3'-phosphoadenosine 5'-phosphosulfate binding activity and alcohol sulfotransferase activity. Involved in several processes, including cellular response to vitamin D; response to activity; and sulfation. Localizes to cytosol. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1); PARTICIPATES IN tamoxifen pharmacokinetics pathway; estradiol biosynthetic pathway; paracetamol pharmacokinetics pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 1-nitropropane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alcohol sulfotransferase; bile salt sulfotransferase; bile-salt sulfotransferase 2A1; hydroxysteroid sulfotransferase a; hydroxysteroid sulfotransferase-like; Smp-2; ST; ST-20; St2; St2a1; STa; Sth2; sulfotransferase 2A1; sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1; Sulfotransferase hydroxysteroid gene 2; sulfotransferase, hydroxysteroid preferring 2
RGD Orthologs
Human
Mouse
Bonobo
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2175,451,178 - 75,508,142 (-)NCBI
Rnor_6.0 Ensembl176,252,329 - 76,780,230 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0176,558,721 - 76,614,315 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0177,849,696 - 77,903,846 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4175,632,632 - 75,708,022 (-)NCBIRGSC3.4rn4RGSC3.4
RH 3.4 Map1767.8RGD
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(5alpha)-cholestan-3beta-ol  (ISO)
1-Hydroxypyrene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropropane  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4'-dichlorobiphenyl  (ISO)
2,4-diaminotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
2,5-dichlorobiphenyl  (ISO)
2,5-dihydroxybenzoic acid  (EXP)
2,6-diaminotoluene  (EXP)
2-acetamidofluorene  (EXP)
2-nitro-p-phenylenediamine  (EXP)
2-nitropropane  (EXP)
3'-phospho-5'-adenylyl sulfate  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,3',5-triiodo-L-thyronine  (EXP)
3,5-dichlorobiphenyl  (ISO)
3-methylcholanthrene  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4-acetylaminofluorene  (EXP)
4-chlorobiphenyl  (ISO)
4-nitro-1,2-phenylenediamine  (EXP)
4-nitrophenol  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
adenosine 3',5'-bismonophosphate  (ISO)
aflatoxin B1  (ISO)
alcohol  (EXP)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
angelicin  (EXP)
antalarmin  (ISO)
astressin  (ISO)
atazanavir sulfate  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
benzoquinones  (ISO)
beta-naphthoflavone  (EXP)
betulin  (ISO)
bexarotene  (EXP)
biochanin A  (EXP)
bisphenol A  (EXP,ISO)
caffeine  (EXP)
calcidiol  (EXP)
carbon nanotube  (ISO)
celecoxib  (ISO)
chenodeoxycholic acid  (ISO)
cholic acid  (ISO)
ciprofibrate  (ISO)
clofibrate  (EXP)
clotrimazole  (EXP)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dehydroepiandrosterone  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP,ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
endosulfan  (ISO)
entacapone  (EXP)
estrone  (ISO)
ethanol  (ISO)
etofenprox  (EXP)
ferulic acid  (EXP)
fipronil  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
furan  (EXP)
gallic acid  (EXP)
gamma-hexachlorocyclohexane  (EXP,ISO)
genistein  (ISO)
ginsenoside Rg1  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
GW 4064  (ISO)
GW 501516  (ISO)
Heliotrine  (ISO)
heptachlor  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
isotretinoin  (ISO)
L-ascorbic acid  (ISO)
leflunomide  (ISO)
lithocholic acid  (EXP,ISO)
methamphetamine  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N,N-dimethylformamide  (ISO)
N-hydroxy-2-acetamidofluorene  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nefazodone  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
paclitaxel  (EXP)
paracetamol  (EXP,ISO)
parathion  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenanthrene  (ISO)
phenobarbital  (EXP,ISO)
phenytoin  (EXP)
pirinixic acid  (EXP,ISO)
potassium bromate  (EXP)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
psoralen  (EXP)
pyrazinecarboxamide  (EXP)
quercetin  (ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quinolin-8-ol  (ISO)
rifampicin  (EXP,ISO)
senecionine  (ISO)
Senkirkine  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
tolcapone  (EXP)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tris(2-chloroethyl) phosphate  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (ISO)
vitamin E  (EXP)
Yangonin  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA)
cytosol  (IDA,ISO)

Molecular Function

References

References - curated
1. Apak TI and Duffel MW, Drug Metab Dispos. 2004 Dec;32(12):1501-8. Epub 2004 Sep 15.
2. Chatterjee B and Roy AK, J Steroid Biochem Mol Biol. 1990 Nov 20;37(3):437-45.
3. Chatterjee B, etal., FASEB J. 1989 Feb;3(2):169-73.
4. Chatterjee B, etal., J Biol Chem 1987 Jan 15;262(2):822-5.
5. Echchgadda I, etal., Mol Pharmacol. 2004 Mar;65(3):720-9.
6. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Kim SY, etal., Drug Metab Dispos. 2005 Nov;33(11):1673-8. Epub 2005 Aug 11.
8. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
9. Kwon EM, etal., Cancer Epidemiol. 2012 Aug;36(4):347-53. Epub 2012 Apr 26.
10. Maiti S, etal., Biochem Biophys Res Commun. 2004 Oct 8;323(1):235-41.
11. Miller WL Rev Endocr Metab Disord. 2009 Mar;10(1):3-17.
12. NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Ogura K, etal., Biochem Biophys Res Commun 1990 Feb 14;166(3):1494-500.
14. Ogura K, etal., Biochem Biophys Res Commun. 1989 Nov 30;165(1):168-74. doi: 10.1016/0006-291x(89)91050-4.
15. Pipeline to import KEGG annotations from KEGG into RGD
16. Pipeline to import SMPDB annotations from SMPDB into RGD
17. RGD automated data pipeline
18. RGD automated import pipeline for gene-chemical interactions
19. Sharp S, etal., Eur J Biochem. 1993 Feb 1;211(3):539-48.
20. Song CS, etal., J Biol Chem 2001 Nov 9;276(45):42549-56.
21. Watabe T, etal., Chem Biol Interact 1994 Jun;92(1-3):87-105.
22. Wilborn TW, etal., J Steroid Biochem Mol Biol. 2006 Jun;99(4-5):209-14. Epub 2006 Apr 17.
Additional References at PubMed
PMID:1588921   PMID:8033248   PMID:16469813   PMID:19548878   PMID:20056724   PMID:21721019   PMID:23026138   PMID:23207770  


Genomics

Comparative Map Data
Sult2a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2175,451,178 - 75,508,142 (-)NCBI
Rnor_6.0 Ensembl176,252,329 - 76,780,230 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0176,558,721 - 76,614,315 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0177,849,696 - 77,903,846 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4175,632,632 - 75,708,022 (-)NCBIRGSC3.4rn4RGSC3.4
RH 3.4 Map1767.8RGD
Cytogenetic Map1q21NCBI
SULT2A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1947,870,467 - 47,886,315 (-)EnsemblGRCh38hg38GRCh38
GRCh381947,870,467 - 47,886,315 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371948,373,724 - 48,389,572 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,065,682 - 53,081,405 (-)NCBINCBI36hg18NCBI36
Build 341953,065,681 - 53,081,405NCBI
Celera1945,179,460 - 45,195,376 (-)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1944,800,492 - 44,816,411 (-)NCBIHuRef
CHM1_11948,375,906 - 48,391,802 (-)NCBICHM1_1
Sult2a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39713,530,171 - 13,571,335 (-)NCBIGRCm39mm39
GRCm39 Ensembl713,530,171 - 13,571,334 (-)Ensembl
GRCm38713,796,246 - 13,837,410 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl713,796,246 - 13,837,409 (-)EnsemblGRCm38mm10GRCm38
MGSCv37714,381,595 - 14,422,759 (-)NCBIGRCm37mm9NCBIm37
MGSCv36714,381,602 - 14,422,724 (-)NCBImm8
Celera711,427,949 - 11,449,279 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map78.02NCBI
SULT2A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11953,517,248 - 53,532,573 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1953,517,248 - 53,532,573 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01944,864,747 - 44,880,688 (-)NCBIMhudiblu_PPA_v0panPan3
SULT2A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,524,765 - 53,536,721 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,525,496 - 53,536,723 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,108,567 - 49,120,453 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SULT2A1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1641,160,707 - 41,175,382 (-)NCBI
ChlSab1.1 Ensembl641,159,978 - 41,175,300 (-)Ensembl

Position Markers
D1Wox13  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0176,720,186 - 76,720,553NCBIRnor6.0
Rnor_6.0176,609,202 - 76,609,589NCBIRnor6.0
Rnor_5.0177,900,170 - 77,900,557UniSTSRnor5.0
Rnor_5.0178,009,693 - 78,010,060UniSTSRnor5.0
RGSC_v3.4174,602,468 - 74,602,835UniSTSRGSC3.4
RGSC_v3.4175,705,354 - 75,705,739RGDRGSC3.4
RGSC_v3.4174,602,467 - 74,602,835RGDRGSC3.4
RGSC_v3.4175,705,355 - 75,705,739UniSTSRGSC3.4
RGSC_v3.1175,783,465 - 75,783,850RGD
Celera170,385,758 - 70,386,127UniSTS
RH 3.4 Map1781.9RGD
RH 3.4 Map1781.9UniSTS
Cytogenetic Map1q21.3-q22.1UniSTS
Cytogenetic Map1q21UniSTS
RH94657  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0176,529,148 - 76,529,260NCBIRnor6.0
Rnor_6.0176,558,755 - 76,558,867NCBIRnor6.0
Rnor_5.0177,849,723 - 77,849,835UniSTSRnor5.0
Rnor_5.0177,823,892 - 77,824,004UniSTSRnor5.0
RGSC_v3.4175,632,659 - 75,632,771UniSTSRGSC3.4
RGSC_v3.4174,553,826 - 74,553,938UniSTSRGSC3.4
Celera170,337,183 - 70,337,295UniSTS
RH 3.4 Map1767.8UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map1q21.3-q22.1UniSTS
BI301823  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0176,144,306 - 76,144,471NCBIRnor6.0
Rnor_5.0177,448,413 - 77,448,578UniSTSRnor5.0
RGSC_v3.4174,453,133 - 74,453,298UniSTSRGSC3.4
Celera170,238,177 - 70,238,342UniSTS
RH 3.4 Map1766.59UniSTS
Cytogenetic Map1q21.3-q22.1UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)125439386904217Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15655769122614963Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1565577285706974Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11131448983657083Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11131448983657083Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11131448983657083Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11131448983657083Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123406428108057505Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)12429779978748000Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)125951907130917265Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13148945479689689Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13444911279449112Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13444911279449112Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134993530173445086Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13537750894364229Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135377692217372257Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13585416780854167Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13585416780854167Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13585416780854167Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13603316579689689Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13603316579689689Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14190724986907249Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143579208126240667Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143579208126240667Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143579208126240667Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143579208126240667Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143579208126240667Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14611346179689689Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)149147799156446783Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14954732883657083Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14957857794578577Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149578577169852184Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149578693217054291Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15052271494225616Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15385134883657083Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15385134883657083Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157761301104391981Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)158209327103209327Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)158354072161711996Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)164588516125875986Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)166113339122614963Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)16722768394201552Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:84
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000041367
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_131903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide D14987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D14988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M31363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NM_131903   ⟹   NP_571978
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2175,451,178 - 75,508,113 (-)NCBI
Rnor_6.0176,558,728 - 76,614,279 (-)NCBI
Rnor_5.0177,849,696 - 77,903,846 (-)NCBI
RGSC_v3.4175,632,632 - 75,708,022 (-)RGD
Sequence:
RefSeq Acc Id: XM_008758891   ⟹   XP_008757113
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2175,464,945 - 75,508,142 (-)NCBI
Rnor_6.0176,571,742 - 76,614,315 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758892   ⟹   XP_008757114
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0176,558,721 - 76,614,314 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_571978 (Get FASTA)   NCBI Sequence Viewer  
  XP_008757113 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41356 (Get FASTA)   NCBI Sequence Viewer  
  BAA03632 (Get FASTA)   NCBI Sequence Viewer  
  BAA03633 (Get FASTA)   NCBI Sequence Viewer  
  P15709 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_571978   ⟸   NM_131903
- UniProtKB: P15709 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008757114   ⟸   XM_008758892
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008757113   ⟸   XM_008758891
- Peptide Label: isoform X1
- Sequence:
Protein Domains
Sulfotransfer_1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689717
Promoter ID:EPDNEW_R241
Type:initiation region
Name:Sult2a2_1
Description:sulfotransferase family 2A, dehydroepiandrosterone -preferring,member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R242  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0176,614,300 - 76,614,360EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 76577319 76577320 C T snv BN/SsN (MCW), WKY/N (MCW), ACI/N (MCW), WN/N (MCW), Buf/N (MCW), M520/N (MCW)
1 76610597 76610598 A G snv CDS, CDR


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621337 AgrOrtholog
Ensembl Genes ENSRNOG00000047986 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002046 UniProtKB/TrEMBL
  ENSRNOP00000043445 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000060238 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002046 UniProtKB/TrEMBL
  ENSRNOT00000041367 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000064593 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24912 UniProtKB/Swiss-Prot
NCBI Gene 24912 ENTREZGENE
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB SULT2A1 RGD
PhenoGen Sult2a1 PhenoGen
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3ZR55_RAT UniProtKB/TrEMBL
  D4AE35_RAT UniProtKB/TrEMBL
  M3ZCQ0_RAT UniProtKB/TrEMBL
  P15709 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A0G2JYC0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-12 Sult2a1  sulfotransferase family 2A member 1  Sult2a1  sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-01   sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1  Sult2a1  sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1  Name updated 1299863 APPROVED
2005-02-28 Sult2a1  sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1  Sth2  sulfotransferase, hydroxysteroid preferring 2  Data Merged 737654 APPROVED
2003-04-09 Sth2  sulfotransferase, hydroxysteroid preferring 2    Sulfotransferase hydroxysteroid gene 2  Name updated 629478 APPROVED
2002-08-07 Sult2a1  sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Sth2  Sulfotransferase hydroxysteroid gene 2      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression present in the rat liver cytosol 634136
gene_regulation mRNA expression is repressed by androgen 634135