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Gene: Col11a1 (collagen type XI alpha 1 chain) Rattus norvegicus
Symbol: Col11a1
Name: collagen type XI alpha 1 chain
Description: Exhibits heparan sulfate binding activity and heparin binding activity. Involved in ossification. Localizes to collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in Marshall syndrome; Stickler syndrome; autosomal dominant nonsyndromic deafness; and fibrochondrogenesis. Orthologous to human COL11A1 (collagen type XI alpha 1 chain); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: collagen alpha-1(XI) chain; collagen type a1(XI)6A-7-8; collagen type a1(XI)6B-7; collagen type XI; collagen, type XI, alpha 1; Procollagen type XI alpha 1; Procollagen type XI alpha 1,; procollagen, type XI, alpha 1
Homo sapiens (human) : COL11A1 (collagen type XI alpha 1 chain)  HGNC  Alliance
Mus musculus (house mouse) : Col11a1 (collagen, type XI, alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col11a1 (collagen type XI alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL11A1 (collagen type XI alpha 1 chain)
Canis lupus familiaris (dog) : COL11A1 (collagen type XI alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col11a1 (collagen type XI alpha 1 chain)
Sus scrofa (pig) : COL11A1 (collagen type XI alpha 1 chain)
Chlorocebus sabaeus (African green monkey) : COL11A1 (collagen type XI alpha 1 chain)
Heterocephalus glaber (naked mole-rat) : Col11a1 (collagen type XI alpha 1 chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02216,863,423 - 217,056,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2216,863,428 - 217,056,523 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02234,955,150 - 235,148,754 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42209,996,467 - 210,193,379 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12210,124,200 - 210,156,132 (+)NCBI
Celera2194,360,332 - 194,556,704 (+)NCBICelera
Cytogenetic Map2q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Col11a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2372
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.