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Gene: Il27 (interleukin 27) Rattus norvegicus
Symbol: Il27
Name: interleukin 27
RGD ID: 1561420
Description: Predicted to have interleukin-27 receptor binding activity. Involved in response to bacterium. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in asthma and chronic obstructive pulmonary disease. Orthologous to human IL27 (interleukin 27); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; lipopolysaccharide; 4-hydroxynon-2-enal (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: interleukin-27 subunit alpha; LOC365368; RGD1561420; similar to IL-27 p28 subunit
Homo sapiens (human) : IL27 (interleukin 27)  HGNC  Alliance
Mus musculus (house mouse) : Il27 (interleukin 27)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il27 (interleukin 27)
Pan paniscus (bonobo/pygmy chimpanzee) : IL27 (interleukin 27)
Canis lupus familiaris (dog) : IL27 (interleukin 27)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il27 (interleukin 27)
Sus scrofa (pig) : IL27 (interleukin 27)
Chlorocebus sabaeus (African green monkey) : IL27 (interleukin 27)
Heterocephalus glaber (naked mole-rat) : Il27 (interleukin 27)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01198,003,615 - 198,010,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,003,683 - 198,008,893 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01204,981,789 - 204,987,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,730,394 - 185,735,604 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1178,831,320 - 178,837,817 (-)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Il27
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561420
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.