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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308085
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col4a2
Name: collagen type IV alpha 2 chain
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col4a2increases expressionISOCol4a2 (Mus musculus)6480464CTDStreptozocin results in increased expression of COL4A2 mRNAPMID:30642005
Col4a2multiple interactionsISOCol4a2 (Mus musculus)6480464CTDMIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA]PMID:30642005
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