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Gene: Acsl1 (acyl-CoA synthetase long-chain family member 1) Rattus norvegicus
Symbol: Acsl1
Name: acyl-CoA synthetase long-chain family member 1
RGD ID: 2015
Description: Exhibits arachidonate-CoA ligase activity; long-chain fatty acid-CoA ligase activity; and phytanate-CoA ligase activity. Involved in several processes, including fatty acid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; and triglyceride biosynthetic process. Localizes to bounding membrane of organelle; endoplasmic reticulum; and plasma membrane. Biomarker of obesity. Orthologous to human ACSL1 (acyl-CoA synthetase long chain family member 1); PARTICIPATES IN adrenoleukodystrophy pathway; carnitine palmitoyltransferase I deficiency pathway; carnitine-acylcarnitine translocase deficiency; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; 1-naphthyl isothiocyanate.
Type: protein-coding
Also known as: Acas; ACS; Acyl CoA synthetase long chain; Acyl CoA synthetase, long chain; arachidonate--CoA ligase; COAA; Facl2; fatty acid Coenzyme A ligase, long chain 2; LACS 1; long-chain acyl-CoA synthetase 1; long-chain-fatty-acid--CoA ligase 1; long-chain-fatty-acid--CoA ligase, liver isozyme; phytanate--CoA ligase
Homo sapiens (human) : ACSL1 (acyl-CoA synthetase long chain family member 1)  HGNC  Alliance
Mus musculus (house mouse) : Acsl1 (acyl-CoA synthetase long-chain family member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acsl1 (acyl-CoA synthetase long chain family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACSL1 (acyl-CoA synthetase long chain family member 1)
Canis lupus familiaris (dog) : ACSL1 (acyl-CoA synthetase long chain family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acsl1 (acyl-CoA synthetase long chain family member 1)
Sus scrofa (pig) : ACSL1 (acyl-CoA synthetase long chain family member 1)
Chlorocebus sabaeus (African green monkey) : ACSL1 (acyl-CoA synthetase long chain family member 1)
Heterocephalus glaber (naked mole-rat) : Acsl1 (acyl-CoA synthetase long chain family member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01648,937,456 - 49,003,898 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1648,937,456 - 49,003,246 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01648,653,023 - 48,719,250 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41649,036,892 - 49,081,416 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11649,036,966 - 49,081,491 (-)NCBI
Celera1643,758,263 - 43,802,634 (-)NCBICelera
Cytogenetic Map16q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acsl1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2015
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.