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Gene: ACSL1 (acyl-CoA synthetase long chain family member 1) Homo sapiens
Symbol: ACSL1
Name: acyl-CoA synthetase long chain family member 1
Description: Exhibits long-chain fatty acid-CoA ligase activity. Involved in lipid biosynthetic process; long-chain fatty acid import into cell; and long-chain fatty acid metabolic process. Localizes to the endoplasmic reticulum and mitochondrion. Biomarker of obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACS1; acyl-CoA synthetase 1; acyl-CoA synthetase long-chain family member 1; arachidonate--CoA ligase; FACL1; FACL2; fatty-acid-Coenzyme A ligase, long-chain 1; fatty-acid-Coenzyme A ligase, long-chain 2; LACS; LACS 1; LACS 2; LACS1; LACS2; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 1; long-chain acyl-CoA synthetase 2; long-chain fatty acid-CoA ligase 2; long-chain fatty-acid-coenzyme A ligase 1; long-chain-fatty-acid--CoA ligase 1; palmitoyl-CoA ligase 1; palmitoyl-CoA ligase 2; paltimoyl-CoA ligase 1; phytanate--CoA ligase
Mus musculus (house mouse) : Acsl1 (acyl-CoA synthetase long-chain family member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Acsl1 (acyl-CoA synthetase long-chain family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acsl1 (acyl-CoA synthetase long chain family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACSL1 (acyl-CoA synthetase long chain family member 1)
Canis lupus familiaris (dog) : ACSL1 (acyl-CoA synthetase long chain family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acsl1 (acyl-CoA synthetase long chain family member 1)
Sus scrofa (pig) : ACSL1 (acyl-CoA synthetase long chain family member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh384184,755,595 - 184,826,593 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374185,676,749 - 185,747,215 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364185,913,743 - 185,984,209 (-)NCBINCBI36hg18NCBI36
Build 344186,051,898 - 186,122,364NCBI
Celera4183,005,275 - 183,075,742 (-)NCBI
Cytogenetic Map4q35.1NCBI
HuRef4181,430,075 - 181,478,058 (-)NCBIHuRef
CHM1_14185,652,944 - 185,723,638 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ACSL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1342971
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.