Acy1 (aminoacylase 1) - Rat Genome Database

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Gene: Acy1 (aminoacylase 1) Rattus norvegicus
Analyze
Symbol: Acy1
Name: aminoacylase 1
RGD ID: 2030
Description: Enables aminoacylase activity. Predicted to be involved in protein catabolic process. Predicted to be located in extracellular exosome. Orthologous to human ACY1 (aminoacylase 1); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2,2-tetramine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ACY IA; ACY IB; ACY-1A; ACY-1B; Acy1a; Acy1b; aminoacylase-1; aminoacylase-1A; aminoacylase-1B; N-acyl-L-amino-acid amidohydrolase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88115,951,068 - 115,956,471 (-)NCBIGRCr8
mRatBN7.28107,072,354 - 107,077,756 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,072,358 - 107,077,682 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,695,324 - 112,700,661 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08110,894,500 - 110,899,837 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,737,280 - 108,742,617 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,134,792 - 115,140,171 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,134,765 - 115,140,080 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,498,889 - 114,504,255 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,576,888 - 111,581,571 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18111,596,342 - 111,601,026 (-)NCBI
Celera8106,384,300 - 106,388,983 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
arsenous acid  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP,ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
finasteride  (EXP)
flutamide  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
indometacin  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
levofloxacin  (EXP)
methimazole  (EXP)
N-nitrosomorpholine  (EXP)
ochratoxin A  (EXP)
paracetamol  (ISO)
perfluorododecanoic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propiconazole  (EXP,ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
selenium atom  (ISO)
streptozocin  (EXP)
succimer  (ISO)
sulfadimethoxine  (EXP)
sulindac  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
triptonide  (ISO)
trovafloxacin  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Rat kidney acylase I: further characterisation and mutation studies on the involvement of Glu 147 in the catalytic process. Durand A, etal., Biochimie. 2003 Oct;85(10):953-62.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The rat kidney acylase I, characterization and molecular cloning. Differences with other acylases I. Giardina T, etal., Eur J Biochem. 2000 Oct;267(20):6249-55.
4. Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning. Mao M, etal., Proc Natl Acad Sci U S A 1998 Jul 7;95(14):8175-80.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15253876   PMID:15489334   PMID:16189514   PMID:17478110   PMID:21082674   PMID:21516116   PMID:25502805   PMID:26514267   PMID:31515488  


Genomics

Comparative Map Data
Acy1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88115,951,068 - 115,956,471 (-)NCBIGRCr8
mRatBN7.28107,072,354 - 107,077,756 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,072,358 - 107,077,682 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,695,324 - 112,700,661 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08110,894,500 - 110,899,837 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,737,280 - 108,742,617 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,134,792 - 115,140,171 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,134,765 - 115,140,080 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,498,889 - 114,504,255 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,576,888 - 111,581,571 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18111,596,342 - 111,601,026 (-)NCBI
Celera8106,384,300 - 106,388,983 (-)NCBICelera
Cytogenetic Map8q32NCBI
ACY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38351,983,535 - 51,989,197 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl351,983,340 - 51,989,197 (+)EnsemblGRCh38hg38GRCh38
GRCh37352,017,551 - 52,023,213 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36351,992,603 - 51,998,258 (+)NCBINCBI36Build 36hg18NCBI36
Build 34351,992,602 - 51,998,258NCBI
Celera351,996,840 - 52,002,495 (+)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef352,080,641 - 52,086,559 (+)NCBIHuRef
CHM1_1351,969,905 - 51,975,823 (+)NCBICHM1_1
T2T-CHM13v2.0352,016,455 - 52,022,117 (+)NCBIT2T-CHM13v2.0
Acy1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,310,180 - 106,315,594 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,310,180 - 106,315,518 (-)EnsemblGRCm39 Ensembl
GRCm389106,432,981 - 106,438,236 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,432,981 - 106,438,319 (-)EnsemblGRCm38mm10GRCm38
MGSCv379106,335,327 - 106,340,567 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369107,224,755 - 107,230,012 (-)NCBIMGSCv36mm8
MGSCv369106,291,097 - 106,296,337 (-)NCBIMGSCv36mm8
Celera9106,060,386 - 106,065,605 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.49NCBI
Acy1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,627,274 - 3,631,799 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,627,314 - 3,631,799 (+)NCBIChiLan1.0ChiLan1.0
ACY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2251,977,814 - 51,983,602 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1351,982,730 - 51,988,372 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0351,924,889 - 51,930,638 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,153,166 - 53,158,941 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,144,802 - 53,158,941 (+)Ensemblpanpan1.1panPan2
ACY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,732,231 - 37,736,986 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,713,721 - 37,726,005 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02038,082,813 - 38,095,105 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,942,559 - 38,095,121 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,446,429 - 37,458,720 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,855,192 - 37,867,484 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02038,140,053 - 38,152,347 (-)NCBIUU_Cfam_GSD_1.0
LOC101960098
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560266,552,867 - 66,573,380 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365293,327,879 - 3,333,879 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365293,308,863 - 3,333,877 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,353,446 - 13,359,274 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,353,588 - 13,359,569 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,547,149 - 153,552,999 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Acy1
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:83
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000015851
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)888612425107550209Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8102370617108923645Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat

Markers in Region
RH131381  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28107,072,527 - 107,072,971 (+)MAPPERmRatBN7.2
mRatBN7.2X19,926,012 - 19,926,229 (+)MAPPERmRatBN7.2
Rnor_6.0X20,002,097 - 20,002,313NCBIRnor6.0
Rnor_6.08115,134,966 - 115,135,409NCBIRnor6.0
Rnor_5.08114,499,063 - 114,499,506UniSTSRnor5.0
Rnor_5.0X20,749,654 - 20,749,870UniSTSRnor5.0
RGSC_v3.48111,577,058 - 111,577,501UniSTSRGSC3.4
RGSC_v3.4X40,266,090 - 40,266,306UniSTSRGSC3.4
CeleraX20,183,575 - 20,183,791UniSTS
Celera8106,384,470 - 106,384,913UniSTS
RH 3.4 Map81138.8UniSTS
Cytogenetic Map8q32UniSTS
Cytogenetic MapXq21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000015851   ⟹   ENSRNOP00000015852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8107,072,366 - 107,077,580 (-)Ensembl
Rnor_6.0 Ensembl8115,134,765 - 115,140,080 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098603   ⟹   ENSRNOP00000082500
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8107,072,366 - 107,077,580 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101252   ⟹   ENSRNOP00000082112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8107,072,358 - 107,077,041 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103409   ⟹   ENSRNOP00000082264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8107,072,358 - 107,077,682 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112946   ⟹   ENSRNOP00000090917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8107,072,358 - 107,077,399 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118284   ⟹   ENSRNOP00000095568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8107,072,366 - 107,077,580 (-)Ensembl
RefSeq Acc Id: NM_001005383   ⟹   NP_001005383
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88115,951,068 - 115,956,405 (-)NCBI
mRatBN7.28107,072,354 - 107,077,691 (-)NCBI
Rnor_6.08115,134,796 - 115,139,479 (-)NCBI
Rnor_5.08114,498,889 - 114,504,255 (-)NCBI
RGSC_v3.48111,576,888 - 111,581,571 (-)RGD
Celera8106,384,300 - 106,388,983 (-)RGD
Sequence:
RefSeq Acc Id: NM_001393838   ⟹   NP_001380767
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88115,951,068 - 115,956,405 (-)NCBI
mRatBN7.28107,072,354 - 107,077,691 (-)NCBI
RefSeq Acc Id: XM_063265237   ⟹   XP_063121307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88115,951,269 - 115,956,471 (-)NCBI
RefSeq Acc Id: NP_001005383   ⟸   NM_001005383
- UniProtKB: Q6PTT1 (UniProtKB/Swiss-Prot),   Q6AYS7 (UniProtKB/Swiss-Prot),   A0A8I5ZVF1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015852   ⟸   ENSRNOT00000015851
Ensembl Acc Id: ENSRNOP00000090917   ⟸   ENSRNOT00000112946
Ensembl Acc Id: ENSRNOP00000095568   ⟸   ENSRNOT00000118284
Ensembl Acc Id: ENSRNOP00000082112   ⟸   ENSRNOT00000101252
Ensembl Acc Id: ENSRNOP00000082264   ⟸   ENSRNOT00000103409
Ensembl Acc Id: ENSRNOP00000082500   ⟸   ENSRNOT00000098603
RefSeq Acc Id: NP_001380767   ⟸   NM_001393838
- UniProtKB: Q6PTT1 (UniProtKB/Swiss-Prot),   Q6AYS7 (UniProtKB/Swiss-Prot),   A0A8I5ZVF1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121307   ⟸   XM_063265237
- Peptide Label: isoform X1
Protein Domains
Peptidase M20 dimerisation

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYS7-F1-model_v2 AlphaFold Q6AYS7 1-408 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696249
Promoter ID:EPDNEW_R6773
Type:initiation region
Name:Acy1_1
Description:aminoacylase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08115,139,953 - 115,140,013EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2030 AgrOrtholog
BioCyc Gene G2FUF-29239 BioCyc
Ensembl Genes ENSRNOG00000011189 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055013030 UniProtKB/Swiss-Prot
  ENSRNOG00060030246 UniProtKB/Swiss-Prot
  ENSRNOG00065008472 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015851.6 UniProtKB/TrEMBL
  ENSRNOT00000098603.1 UniProtKB/TrEMBL
  ENSRNOT00000101252.1 UniProtKB/TrEMBL
  ENSRNOT00000103409.1 UniProtKB/TrEMBL
  ENSRNOT00000112946.1 UniProtKB/TrEMBL
  ENSRNOT00000118284.1 UniProtKB/TrEMBL
  ENSRNOT00055022347 UniProtKB/Swiss-Prot
  ENSRNOT00060052661 UniProtKB/Swiss-Prot
  ENSRNOT00065013445 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.900 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zn peptidases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7107165 IMAGE-MGC_LOAD
InterPro Aminoacylase-1_M20A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArgE/DapE_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bact_exopeptidase_dim_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  N-acyl_aa_amidohydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M20_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:300981 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93728 IMAGE-MGC_LOAD
NCBI Gene Acy1 ENTREZGENE
PANTHER AMINOACYLASE-1 UniProtKB/Swiss-Prot
  AMINOACYLASE-1 UniProtKB/Swiss-Prot
  AMINOACYLASE-1 UniProtKB/TrEMBL
  AMINOACYLASE-1 UniProtKB/TrEMBL
Pfam M20_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Acy1 PhenoGen
PIRSF ACY-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARGE_DAPE_CPG2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARGE_DAPE_CPG2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011189 RatGTEx
  ENSRNOG00055013030 RatGTEx
  ENSRNOG00060030246 RatGTEx
  ENSRNOG00065008472 RatGTEx
Superfamily-SCOP SSF55031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZU87_RAT UniProtKB/TrEMBL
  A0A8I5ZUM3_RAT UniProtKB/TrEMBL
  A0A8I5ZVF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABX8_RAT UniProtKB/TrEMBL
  A0A8I6ANP4_RAT UniProtKB/TrEMBL
  A0A8L2Q7R2_RAT UniProtKB/TrEMBL
  ACY1A_RAT UniProtKB/Swiss-Prot
  ACY1B_RAT UniProtKB/Swiss-Prot
  Q6AYS7 ENTREZGENE
  Q6PTT0 ENTREZGENE
  Q6PTT1 ENTREZGENE
UniProt Secondary Q6PTT1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Acy1  Aminoacylase 1      Symbol and Name status set to approved 70586 APPROVED