LOC101960098 (aminoacylase-1) - Rat Genome Database

Name: LOC101960098
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Advanced Search (OLGA)

Gene: LOC101960098 (aminoacylase-1) Ictidomys tridecemlineatus

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Symbol:

LOC101960098 (Ensembl: ACY1)

Name:

aminoacylase-1 (Ensembl:aminoacylase 1)

RGD ID:

12502606

Description:

ENCODES a protein that exhibits aminoacylase activity (ortholog); INVOLVED IN amino acid metabolic process (inferred); ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (inferred); extracellular exosome (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Acy1; aminoacylase 1; aminoacylase-1, transcript variant X1; aminoacylase-1, transcript variant X2

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACY1 (aminoacylase 1)	NCBI	Ortholog
Mus musculus (house mouse):	Acy1 (aminoacylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Acy1 (aminoacylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Acy1 (aminoacylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACY1 (aminoacylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACY1 (aminoacylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACY1 (aminoacylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	66,552,867 - 66,573,380 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	3,327,879 - 3,333,879 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	3,308,863 - 3,333,877 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aminoacylase 1 Deficiency (ISO)

genetic disease (ISO)

intellectual disability (ISO)

pre-malignant neoplasm (ISO)

renal cell carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amino acid metabolic process (IEA)

Cellular Component

cytoplasm (IEA)

extracellular exosome (IEA)

Molecular Function

aminoacylase activity (IEA,ISO)

hydrolase activity (IEA)

identical protein binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC101960098
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	66,552,867 - 66,573,380 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	3,327,879 - 3,333,879 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	3,308,863 - 3,333,877 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACY1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	51,983,535 - 51,989,197 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	51,983,340 - 51,989,197 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	52,017,551 - 52,023,213 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	51,992,603 - 51,998,258 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	51,992,602 - 51,998,258	NCBI
Celera	3	51,996,840 - 52,002,495 (+)	NCBI		Celera
Cytogenetic Map	3	p21.2	NCBI
HuRef	3	52,080,641 - 52,086,559 (+)	NCBI		HuRef
CHM1_1	3	51,969,905 - 51,975,823 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	52,016,455 - 52,022,117 (+)	NCBI		T2T-CHM13v2.0

Acy1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	106,310,180 - 106,315,594 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	106,310,180 - 106,315,518 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	106,432,981 - 106,438,236 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	106,432,981 - 106,438,319 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	106,335,327 - 106,340,567 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	107,224,755 - 107,230,012 (-)	NCBI		MGSCv36	mm8
MGSCv36	9	106,291,097 - 106,296,337 (-)	NCBI		MGSCv36	mm8
Celera	9	106,060,386 - 106,065,605 (-)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	57.49	NCBI

Acy1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	115,951,068 - 115,956,471 (-)	NCBI		GRCr8
mRatBN7.2	8	107,072,354 - 107,077,756 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	107,072,358 - 107,077,682 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	112,695,324 - 112,700,661 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	110,894,500 - 110,899,837 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	108,737,280 - 108,742,617 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	115,134,792 - 115,140,171 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	115,134,765 - 115,140,080 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	114,498,889 - 114,504,255 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	111,576,888 - 111,581,571 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	111,596,342 - 111,601,026 (-)	NCBI
Celera	8	106,384,300 - 106,388,983 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

Acy1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	3,627,274 - 3,631,799 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	3,627,314 - 3,631,799 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACY1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	51,977,814 - 51,983,602 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	51,982,730 - 51,988,372 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	51,924,889 - 51,930,638 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	53,153,166 - 53,158,941 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	53,144,802 - 53,158,941 (+)	Ensembl	panpan1.1		panPan2

ACY1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	37,732,231 - 37,736,986 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	37,713,721 - 37,726,005 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	38,082,813 - 38,095,105 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	37,942,559 - 38,095,121 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	37,446,429 - 37,458,720 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	37,855,192 - 37,867,484 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	38,140,053 - 38,152,347 (-)	NCBI		UU_Cfam_GSD_1.0

ACY1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	13,353,446 - 13,359,274 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	13,353,588 - 13,359,569 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	153,547,149 - 153,552,999 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013359429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021727529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000002601 ⟹ ENSSTOP00000002326

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936529	3,327,879 - 3,333,879 (+)	Ensembl

RefSeq Acc Id:

XM_013359429 ⟹ XP_013214883

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	66,567,236 - 66,573,380 (+)	NCBI
SpeTri2.0	NW_004936529	3,327,782 - 3,333,877 (+)	NCBI

Sequence:

show sequence

CGGAACCTTCTCGGGGTGGAGCCAGCCCCCAACGTGCCGCCTGTGGGGCGGAGCTGGCGGCGGC
CAGAGCTGCCCAGGGGGCGGGATCCTGGATTCAAGCCTCCAATAACTCAGTGGAGGTCCTGCTC
GGTGGAGGACCCGGACCTAGGCGCCTACACTGCCGCAGGGAGTGGGCAGGTTGTGACTTGCAAT
CTGCGATATCCGCCCCGCGACCCGGCTTTGGGCCAAGTGGTGAGCGGATTAGGGCAGTTTTGAT
CTCGCGACCTTGCTGGACCCGGAGTCCCCGCCACATTTCTCGCAGCGGGAGCTGAAAGGCGAAC
GCCGGCCCAAGACCAGGAGAAAGAAAGCTTACCACGATCGGAGCCATGGCCAGCAAGGATCCTG
AGTCTGAGCACCCATCTGTGACGCTGTTCCGCCAGTACCTGCGCATCCGCACTGTCCACCCTAA
TCCCGACTATGGCACTGCTGTGGCCTTTTTTGAGGAGAGAGCCCACCAGCTAGGCCTGAGCTTT
CAGAAAGTGGAGGTGACACCTGGCTATGTGGTCCCTGTGCTAACTTGGCCAGGCACCAACCCTA
CACTCTCCTCCATCTTGCTCAACTCCCATATGGATGTGGTACCTGTCTTCAAGGAACATTGGAG
TCATGACCCCTTTGAGGCCTTCAAGGATTCTGAGGGCTACATCTATGCCAGGGGCACCCAAGAC
ATGAAGAGTGTCAGCATCCAGTACCTGGAAGCTGTGAGAAGGCTGAAGGTTGAGGGCCACCGTT
TTCCTAGAACCATCCACATGACCTTTGTACCTGATGAGGAAATCGGAGGTCACAAAGGCATGGA
GCTGTTCGTACAGCGGCCTGAGTTCCAGGCCCTGAGGGTGGGATTTGCCCTGGATGAGGGCCTG
GCTAACCCCACTGATGCCTTCACTGTCTTTTATAGTGAGCGGAGCCTCTGGTGGGTGCGGTTTA
CCAGCTCTGGGAGGCCAGGCCATGGGTCACGCTTCATTGAGGACACAGCAGCAGAGAAGCTGCA
CAAAGTTGTGAGCTCCATCTTGGCATTCCGGGAGAAGGAAAGGCAGAGGCTGCAGTCAAACCCT
CATCTGAAGGAGGGGGCCGTAACCTGTGTGAACCTGACTAAGCTAGAGGGTGGTGTGGCTTATA
ATGTGGTACCCGCCACTATGAGCGCCAGCTTTGACTTCCGCTTGGCACCAGATGTGGACCTGCA
GGCTTTTGAGAAGCAGCTACAGAGCTGGTGCCAGGCAGCTGGTGAGGGTGTCACCTTCGAGTTT
GTTCAGAGGTGGATGAAGCCCCGAGTGACACCTATTGATGATGCAAACCCCTGGTGGGCGGCTT
TTAACCGGGTCTGCAAGGACATGAACCTCACTCTAGAGCCGGAGATCTTCCCTGCTGCCACTGA
TAGCCGCTATCTCCGTGCGGTGGGGATCCCAGCTCTAGGCTTCTCACCCATGAACCGCACACCT
GTGCTGCTGCATGACCATGATGAGCGGTTGCATGAGACCGTGTTCCTTCGTGGGATTGACATAT
ACATGCGCTTGCTATCTGTTCTGGCCAGTGTGCCTGCCCTGCCCAATGAAAAATGAGCCCCATA
CCCTCCAGGCTGCCCCAGAGCTTTCATCCCAACCAGTGCCAAGGACCTCCTCTTCTCCTGACCA
GTAATGTAGCCTGTGTGGACAAAGGCAGCTCCTAAATACTAACACTGCACACATTCATGGAGAA
GGGAGTCTTATTACTCTGGGGACATGCTGTTACCAACCCAGTTTCACAGATGAGGAAACAGCTT
GGCTCTGTGCCCTCATGACATAACACACTGTCCCAGCCACATCTGCCTAGCAACAAGGGGCCAT
AGTTCAATGGCCACCATATTCTGACTGTGAGGTCAGGGATACTGTTCCCATCAAAAGGGCATAA
GTGTAATGCTAGTAACTCAGGAGGCCAACGTAGGAGGATCTCAAGTTTGAGGCCAGGCTTAGCA
AAACCATTTCAAAACAAAAAAACAAACAAACAAAGCCTGGGGATGTGGTTATGACATAGAACAC
CCCTGGTTCAATCTCCAGTACCATAAAGGAGCATACCAAGATTAGCGTCTCAGGGAACTACTCC
TGGCTTTCTGGGGATATACTCAGGATCCTGGGACCAGATGGGCCACTGCCAGGTGGGTAGGCAG
AGACAGCTTGCAAGGTATGAGCACCCTTTTTTTTTTTTTTTTTTTTGTTCTATTTGGTCAAAAC
CCACTGACTCTTGTGTTGGGAGTAGGGCCTTGATAGATCCAGCAGACTGGCCAGTGATCATGAA
TCATTGTGTGCAGAGGGGCCCAGGAGTTGAGTTTCAATCTGTCAGCCCTTGTCAGGATCCCATT
TGATATAACTAAAGCCATCTTGATTATAACCATTTGCCTGCCTGGAACCCTGCTATATACTCCA
AAACCTATAGGATATATCAAGCCATTAAGGTAGTCAGCTAGCTTAACTGACATTTGACATATTA
GTTTTTGTTGCTTTTTCTCCTCCTTCTTTTTGAGAAAACCCAGACAGATCCCAGTCGGCTGTGG
GTGTGGGCTACCTTTATTTAGTTTGACATATAAACCCCTTCCTCCTGCCTCAGGGTGCAAGGAT
CCTCCTGTTGCTGCCCAAGACCTGCTTCTTTCCTTAACCCTAATAAATTGCATTTTATACAAA

hide sequence

RefSeq Acc Id:

XM_021727529 ⟹ XP_021583204

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	66,552,867 - 66,573,380 (+)	NCBI
SpeTri2.0	NW_004936529	3,308,863 - 3,333,877 (+)	NCBI

Sequence:

show sequence

TCTATCCTCAGCACCCCCCAAAAGAAAAAAAAAAAAAAAGAGGAATTAACTAGGAAACTTATGA
GAATCAAAAAAAGGCATCCTCTTCCCTGAAAGAGAGGATCCCTGTGGATAGGATCTTGAAGGTG
GAATTAAGGTTGAAATTTTAACTTTAAATAAAAGGAGGAGAACTGGGCACCTCCCTTCCCAATT
ATATTGCCCACCTCCTGCAAACAAGACAAGAATGGAGTCAGATGGACACCAAAGGCCCAACTAT
GGCTCCTCTCCTCACCCTGGCAGGATGAGGCCAGAGCCCACTGGCTTTTGTGCAAAGCAGCAGC
TGGAGAGTAAGCTGATGCAGAAAATGGAGATCTTGAAGGGAGGGTAGCCAGGTGGGTGGTGAGG
CTCTAGCCCTCCTGCCCTTCCTTCCCCCTGTCTGGCAAAGGCCACCCCCAGAGGCATCCCATCT
ACTAGAGGTCACTAGAGTTGAGGCTCCATGCAGATAGCTCTGGGCAGGATGCACTCAGCACTCA
ATAGGGACGGGGGTTGGTCAGCAGCTGGCACAACAGTGTTTCCAATCCCTTTCCTATTTGTGGA
GAATGGCCCTGGGCACCGAAGGCAAGAAACATCCAGGCTGGCCACATTCCCTGCCTTGAACACT
TTCTACTGTATCACAAAAAAACTCGTTTTGAATTCTGGGGTCTCAGTTTCCTCACTTATAAAAC
AGATGACGTTTCCTTGGGACTGTACTTGGTAAGAAAGGTATTTGGTGGGCTGCAAGAATGTCAA
GGCCATTAAACGGATGGAGGAAGGTGGAGCCTGAGATTAGCTACTGGGATTAGCTCAGCCACCA
ACCCTCCCCACCCCGACCCCTTTTCATGCCCCAATTTAATCCTGAACTTAATCCTGCTTAGAAA
TCCTTCTTCAGAGGCCATCTCCCTCCAAGGTTCAGCTTTTGATGAGGAGCTCACTGAGGGACCA
AAACACATGAAAGACAGGGAGTGGGACCAACTGATGCCAAATCTGGGCCCAGACTAAGCCCTCT
CCCTACAAATTTCTTCTACCTGGAAGACTATGGGGGCAAAGGAGGAGTGTACTGGATATGAAAC
ACCTGGAAGGCCTCTCGATATCTTTCTCCTCAGCCCCCTGTCCCATTCTAACATAAGGGTCAAG
GGCACAGAGCTCTGTCCAAGGCCCTCTTCTAACCTTCCCTCGCACTAGTGGAGCATAGGTGGGA
AGTGGAAAGTGGGGCTCTCCACCTGTTTTTTCTCAGGAAACCTGAGCAAGCCACTGTATGGCAT
GCAGTATCCTTTTTCTCATCTATACAAAATGAGGATGACAGCTCTGTTCCCCGGCTCATTTCCC
TAGGCACCTGCTCCTCCTTCCATTTGAGTTCTGCCACAGGCTCACCAAAGGGGAGAGATCAGCA
GTAGACGCAGGGACTGTGCTCTCTGGACATCCTGGCCAACCTAATGCTGGCTGCCCTTGCTAGA
CATTCCCCTGGCTGCCTGCACTTCCCCCATCAAAGCACTGTGATGACGTGCTTGGTTTCTGTCT
CCCTGGGCAGCCAAGCCTGGGAGCCCCTTAGAGCAGGAGCCAAGGCTGCCACCTTCTGCTTGTG
TCCCCTGGGGCTCAGTTCAGAGCTGGGCCAGAGAAGGTGCTCAAACATCCTGGTGATCTGAGAT
GATTTCACTGCACAGAAGGGGAACCTGATACCTAAAGAGGGTCTTAACCTGCCCAAGGTCACAG
AGAGAAGGGGAATTAAGAGACCAGCAGGGTCCTACCTGCTAGCACGGGCCTGAATCACGCCCCA
TGTGTGTCCCCTTTCGGGTCGCTCTTGTCTAGGTCTGCTAGTCCTCTTTCTGGAGGTCGGGCTT
TTCAGGGTGGGATTGCAGGCTTTGATTGTCTCAGAAACCCCTGCCTGGCTAGTGGACAGTGGCT
AGTGGCTAGTGGGTCTTGTTTGGAGAGGACTGACAGGTAGTCCAAAGAAACAGTCCTGAACTCC
AGAATTTGGGGGTGGGGCAAAGGGATCCACTTTGGGGAGGTATCCTTTGGGAGAAATGACACTG
TGTCCCCATACCGTCTCATCACCTCTTATAGCCCCAGGAAAAACAGGGCAGGAGGGCTGGAACC
TGGCCAGAACTGGAGCTCCTGCCATGAAAAAGACACCTGGGTCTGCAACAGAGACTCACTGCCC
TAAATTCAACTGGTGACCTTGGCCCAGCCTTCCCCTGATCTCAGGACCTCAGTTTACCCACCTG
AACTATGTTTGGGGGATGGGATGGGGGAGACTTGCTGGTTTCTTTGTGTCTTTTCTGTTCTGAG
AGACCCTCAAGGTCTTTCCTGTCTTTCAGAGAGAACAGGGGGTCCTGATATATGTCTTTCAGAT
TATTCTCCTATAGCCCTAAAAATAAGCAGCCCCTGTTAAGCTTTACTGGCTCCCCTGCCCTCCC
TGGGGCTCTAGAGAGTTACTTGCTGCTCCAGTCTGGTGGGTTTTGGGTCTCTGCTGGGCCACCC
ACGTGGCAGCCACACATCATGCCACACTGACCTCCAGCTCACCTCTGAGGGTGCCCAGCCCCCT
CTGGTCAGCAGGGCTCCCTGGCAGAACATACCAAGCTCAGATCAGGCCTCTGACCTCGGGCTTT
CCCTCCTGCTCCCCAGGCCCCCTCCCCAGACCCGGTGCCCACTCCTTCTGTCCCTGGCTTCCTG
CCACTCAGGCTGGAAGGGGTGGGGGGGTGACAGCTGTGTAAGCAATGGTGGCTGCCCCCTTCCT
GCCCCTCCCCCCCAGCTGTCTCTCTCCCATGACAGCTGCCCAATCAAAGGGCCGGGGGCTTAGC
CAGCTCCCCCCACATGCAGGGATCAAGTGTCCACCCTGGCTTTGTTCTGGAGCAAGAACAATCC
GGGGGAGGGGAGGGCTCCTGGGGCTAGGCAACTCAAGTAGACTGGCCCACCCCTTGGGGATTCC
CTTGTCTCTTCTGGCCAGAGTATCTGGACCAGTTGGGGGCCTGTGGACCCACCTGGATGAGAGA
AAGGGGGATCCAGTCTCAGCTTTATCCCCCACCTCACATCCCTCAATTTCTCCCTCAGCTCTCC
CAGCTCCCAACCTAGCAGCTTACTTCTCCTATTCCAAAAGCAGTCATGCAGGCCACACCCAGTG
ATGCTAGGGAATGGCTCAGAGCATCAGGCAAGGCAGGGTGTGGCAGGAGGTGGACACTGGGCAG
GGGGCAGGGGGTCAGCATGGAGGGCTACTGGCTCCCCTGCCTGTAGCCTAATTGAGGGATGCTC
ACCCTTGCTGATTAGCTAGACCACCACAAAAACTGCCCCTCAGACCATGGGCCCAGCCTCAGCC
TTTCAGTCTCCCTTTGGAAGGAGAAGGGGAGAGCAGCCTGGGGTCTATAAGCTCCAGACTCTGG
TTTCTTGCTTTGGGTCTATTTCATAGACAAAGTAAAGAAGGGGGAGCTTGGAAAGGGGACCTCT
GATAAATTCCCCTTATCAGAAGCTATAAATGCTACAGCCTCCCCTCCTCAGGGCATCATTAGAT
AGCCCCAAAGAGTCTTCACAACCAAGGGAAACTAGATTGGGCTCAGGAGAAATGCCACAGCACC
ACTCACTGGTACCCACTCCTGCATGATCTCACTCAAATTGAGAAAGATCTCTGGCTTCCATTCT
CCATGCTAAAGACAGCGCACTTTCTCTGCCGCTCAGTAGCCATGATTCCCAGAACCCAAAGAGT
AAACCCATAGACAGGCAATCAAGGCCCTTCATGGTCCATCCCCTGCTAACTCTTCTTGTCTCAT
CTCTACCCCATCCCCCATACAGGTCAGGCTGCAGAACCACCTCTTACCACCTCCAGGCCTCTGG
GCCTTTGCCCAGGCTGATGATCCCAGTTTGAAAGGCCCATCCTCCTCACTCTCTATCAAAATCC
TTCTCAAATGCCACCTCCTCTGTGGAGCCTTCCCCAACCTTCCAAGTCAGATGAGACACACTCA
GGCCTCTGTGCCCCCAAAGATATGGCTGTAACTCAAAGGAATCCCAGTTGAGCATTTCAGAGCC
CGTCCTTCCACTACCCTGAGAGATTCAGGAGGATAAGAAATTTGAGACAGGACCAGGCTCAGAA
TACAGGCAGAATTGTTAGGGCTCACAGGGCCTGAGATCGCTAGAGACCATGAGGCTCACCTAAG
GACCCAGGGTTGAAGGACTAGCCACATGGGCAGAGAGCCAGGCTCTACCTGGATAGGATTCTCA
GTTCTTTCTCAGCACCCAGTAGCCCCTACTCCTGCTGTTTTGGGGGGTCTAGAGGCTCCCTGGG
CATGTTGCTGGAATGAAGAATTTGGACTGTGTTTTGAGATTTCTAGGGAATCAGAATAGGCTAC
CCAAGAAGGGGGGTTGTAAGAAGCACTAGAGCATGGGATAGGTTTCACAGAACTGAGTTGGGTT
CAGCCTATCACAACTAGAAAGGCTTCACCAATCAAGAGAAGAACCTGAGGTCCAGAATATAAGG
GAATTGTTTGTAAGACTACATGCCACAACTGGCAGACTGGGAGAACCCGGGGTCCACCTGGGCA
GCTCAATGCTCATTCCTCAAGAGGTTGGTGCCACTGGGCAACGGTGATGGAGACTGGAGGAGAG
AGGCAGTGATGGGAGTAGGCTTACCACGATCGGAGCCATGGCCAGCAAGGATCCTGAGTCTGAG
CACCCATCTGTGACGCTGTTCCGCCAGTACCTGCGCATCCGCACTGTCCACCCTAATCCCGACT
ATGGCACTGCTGTGGCCTTTTTTGAGGAGAGAGCCCACCAGCTAGGCCTGAGCTTTCAGAAAGT
GGAGGTGACACCTGGCTATGTGGTCCCTGTGCTAACTTGGCCAGGCACCAACCCTACACTCTCC
TCCATCTTGCTCAACTCCCATATGGATGTGGTACCTGTCTTCAAGGAACATTGGAGTCATGACC
CCTTTGAGGCCTTCAAGGATTCTGAGGGCTACATCTATGCCAGGGGCACCCAAGACATGAAGAG
TGTCAGCATCCAGTACCTGGAAGCTGTGAGAAGGCTGAAGGTTGAGGGCCACCGTTTTCCTAGA
ACCATCCACATGACCTTTGTACCTGATGAGGAAATCGGAGGTCACAAAGGCATGGAGCTGTTCG
TACAGCGGCCTGAGTTCCAGGCCCTGAGGGTGGGATTTGCCCTGGATGAGGGCCTGGCTAACCC
CACTGATGCCTTCACTGTCTTTTATAGTGAGCGGAGCCTCTGGTGGGTGCGGTTTACCAGCTCT
GGGAGGCCAGGCCATGGGTCACGCTTCATTGAGGACACAGCAGCAGAGAAGCTGCACAAAGTTG
TGAGCTCCATCTTGGCATTCCGGGAGAAGGAAAGGCAGAGGCTGCAGTCAAACCCTCATCTGAA
GGAGGGGGCCGTAACCTGTGTGAACCTGACTAAGCTAGAGGGTGGTGTGGCTTATAATGTGGTA
CCCGCCACTATGAGCGCCAGCTTTGACTTCCGCTTGGCACCAGATGTGGACCTGCAGGCTTTTG
AGAAGCAGCTACAGAGCTGGTGCCAGGCAGCTGGTGAGGGTGTCACCTTCGAGTTTGTTCAGAG
GTGGATGAAGCCCCGAGTGACACCTATTGATGATGCAAACCCCTGGTGGGCGGCTTTTAACCGG
GTCTGCAAGGACATGAACCTCACTCTAGAGCCGGAGATCTTCCCTGCTGCCACTGATAGCCGCT
ATCTCCGTGCGGTGGGGATCCCAGCTCTAGGCTTCTCACCCATGAACCGCACACCTGTGCTGCT
GCATGACCATGATGAGCGGTTGCATGAGACCGTGTTCCTTCGTGGGATTGACATATACATGCGC
TTGCTATCTGTTCTGGCCAGTGTGCCTGCCCTGCCCAATGAAAAATGAGCCCCATACCCTCCAG
GCTGCCCCAGAGCTTTCATCCCAACCAGTGCCAAGGACCTCCTCTTCTCCTGACCAGTAATGTA
GCCTGTGTGGACAAAGGCAGCTCCTAAATACTAACACTGCACACATTCATGGAGAAGGGAGTCT
TATTACTCTGGGGACATGCTGTTACCAACCCAGTTTCACAGATGAGGAAACAGCTTGGCTCTGT
GCCCTCATGACATAACACACTGTCCCAGCCACATCTGCCTAGCAACAAGGGGCCATAGTTCAAT
GGCCACCATATTCTGACTGTGAGGTCAGGGATACTGTTCCCATCAAAAGGGCATAAGTGTAATG
CTAGTAACTCAGGAGGCCAACGTAGGAGGATCTCAAGTTTGAGGCCAGGCTTAGCAAAACCATT
TCAAAACAAAAAAACAAACAAACAAAGCCTGGGGATGTGGTTATGACATAGAACACCCCTGGTT
CAATCTCCAGTACCATAAAGGAGCATACCAAGATTAGCGTCTCAGGGAACTACTCCTGGCTTTC
TGGGGATATACTCAGGATCCTGGGACCAGATGGGCCACTGCCAGGTGGGTAGGCAGAGACAGCT
TGCAAGGTATGAGCACCCTTTTTTTTTTTTTTTTTTTTGTTCTATTTGGTCAAAACCCACTGAC
TCTTGTGTTGGGAGTAGGGCCTTGATAGATCCAGCAGACTGGCCAGTGATCATGAATCATTGTG
TGCAGAGGGGCCCAGGAGTTGAGTTTCAATCTGTCAGCCCTTGTCAGGATCCCATTTGATATAA
CTAAAGCCATCTTGATTATAACCATTTGCCTGCCTGGAACCCTGCTATATACTCCAAAACCTAT
AGGATATATCAAGCCATTAAGGTAGTCAGCTAGCTTAACTGACATTTGACATATTAGTTTTTGT
TGCTTTTTCTCCTCCTTCTTTTTGAGAAAACCCAGACAGATCCCAGTCGGCTGTGGGTGTGGGC
TACCTTTATTTAGTTTGACATATAAACCCCTTCCTCCTGCCTCAGGGTGCAAGGATCCTCCTGT
TGCTGCCCAAGACCTGCTTCTTTCCTTAACCCTAATAAATTGCATTTTATACAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013214883	(Get FASTA)	NCBI Sequence Viewer
	XP_021583204	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000002326.2
GenBank Protein	KAG3270599	(Get FASTA)	NCBI Sequence Viewer
	KAG3270600	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013214883 ⟸ XM_013359429

- UniProtKB:

I3M0R1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASKDPESEHPSVTLFRQYLRIRTVHPNPDYGTAVAFFEERAHQLGLSFQKVEVTPGYVVPVLT
WPGTNPTLSSILLNSHMDVVPVFKEHWSHDPFEAFKDSEGYIYARGTQDMKSVSIQYLEAVRRL
KVEGHRFPRTIHMTFVPDEEIGGHKGMELFVQRPEFQALRVGFALDEGLANPTDAFTVFYSERS
LWWVRFTSSGRPGHGSRFIEDTAAEKLHKVVSSILAFREKERQRLQSNPHLKEGAVTCVNLTKL
EGGVAYNVVPATMSASFDFRLAPDVDLQAFEKQLQSWCQAAGEGVTFEFVQRWMKPRVTPIDDA
NPWWAAFNRVCKDMNLTLEPEIFPAATDSRYLRAVGIPALGFSPMNRTPVLLHDHDERLHETVF
LRGIDIYMRLLSVLASVPALPNEK

hide sequence

RefSeq Acc Id:

XP_021583204 ⟸ XM_021727529

- UniProtKB:

I3M0R1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASKDPESEHPSVTLFRQYLRIRTVHPNPDYGTAVAFFEERAHQLGLSFQKVEVTPGYVVPVLT
WPGTNPTLSSILLNSHMDVVPVFKEHWSHDPFEAFKDSEGYIYARGTQDMKSVSIQYLEAVRRL
KVEGHRFPRTIHMTFVPDEEIGGHKGMELFVQRPEFQALRVGFALDEGLANPTDAFTVFYSERS
LWWVRFTSSGRPGHGSRFIEDTAAEKLHKVVSSILAFREKERQRLQSNPHLKEGAVTCVNLTKL
EGGVAYNVVPATMSASFDFRLAPDVDLQAFEKQLQSWCQAAGEGVTFEFVQRWMKPRVTPIDDA
NPWWAAFNRVCKDMNLTLEPEIFPAATDSRYLRAVGIPALGFSPMNRTPVLLHDHDERLHETVF
LRGIDIYMRLLSVLASVPALPNEK

hide sequence

Ensembl Acc Id:

ENSSTOP00000002326 ⟸ ENSSTOT00000002601

Protein Domains

Peptidase M20 dimerisation

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000002597	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000002601.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.150.900	UniProtKB/TrEMBL
	3.30.70.360	UniProtKB/TrEMBL
	Zn peptidases	UniProtKB/TrEMBL
InterPro	Aminoacylase-1_M20A	UniProtKB/TrEMBL
	ArgE/DapE_CS	UniProtKB/TrEMBL
	Bact_exopeptidase_dim_dom	UniProtKB/TrEMBL
	N-acyl_aa_amidohydrolase	UniProtKB/TrEMBL
	Peptidase_M20	UniProtKB/TrEMBL
	Peptidase_M20_dimer	UniProtKB/TrEMBL
NCBI Gene	Acy1	ENTREZGENE
PANTHER	AMINOACYLASE-1	UniProtKB/TrEMBL
	AMINOACYLASE-1	UniProtKB/TrEMBL
Pfam	M20_dimer	UniProtKB/TrEMBL
	Peptidase_M20	UniProtKB/TrEMBL
PIRSF	ACY-1	UniProtKB/TrEMBL
PROSITE	ARGE_DAPE_CPG2_1	UniProtKB/TrEMBL
	ARGE_DAPE_CPG2_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55031	UniProtKB/TrEMBL
	Zn-dependent exopeptidases	UniProtKB/TrEMBL
UniProt	I3M0R1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-07-13	LOC101960098	aminoacylase-1	Acy1	aminoacylase 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM