SET domain containing 7, histone lysine methyltransferase
RGD ID:
1586346
Description:
Enables chromatin binding activity. Involved in positive regulation of DNA-templated transcription and response to ethanol. Located in nucleus. Used to study extrahepatic cholestasis. Orthologous to human SETD7 (SET domain containing 7, histone lysine methyltransferase); PARTICIPATES IN carnitine biosynthetic pathway; histone modification pathway; methionine cycle/metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter], TGFB1 protein promotes the reaction [Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter]]
Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter], TGFB1 protein promotes the reaction [Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter]]
Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter], TGFB1 protein promotes the reaction [Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter]]
[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SETD7 mRNA
[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SETD7 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SETD7 mRNA
Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in beta-endorphin-producing POMC neurons of the hypothalamus.
SET domain containing (lysine methyltransferase) 7
LOC689954
similar to Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7)
Nomenclature updated to reflect human and mouse nomenclature
similar to Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7)
LOC679429
similar to Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7)
similar to Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7)
similar to Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7)