Ckmt2 (creatine kinase, mitochondrial 2) - Rat Genome Database

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Gene: Ckmt2 (creatine kinase, mitochondrial 2) Rattus norvegicus
Analyze
Symbol: Ckmt2
Name: creatine kinase, mitochondrial 2
RGD ID: 61977
Description: Enables cardiolipin binding activity. Involved in heart development and skeletal muscle tissue development. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human CKMT2 (creatine kinase, mitochondrial 2); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH 3-guanidinopropanoic acid; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: basic-type mitochondrial creatine kinase; creatine kinase S-type, mitochondrial; creatine kinase, mitochondrial 2, sarcomeric; MGC187999; mib-CK; S-MtCK; sarcomeric mitochondrial creatine kinase; similar to creatine kinase, mitochondrial 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2223,079,920 - 23,110,518 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl223,079,918 - 23,110,430 (-)Ensembl
Rnor_6.0221,422,680 - 21,452,797 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl221,422,818 - 21,437,193 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0240,627,924 - 40,657,402 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4222,084,948 - 22,106,014 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1222,005,331 - 22,026,403 (-)NCBI
Celera219,182,609 - 19,209,711 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Cardiolipin is the membrane receptor for mitochondrial creatine phosphokinase. Muller M, etal., J Biol Chem. 1985 Mar 25;260(6):3839-43.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Developmental expression of sarcomeric and ubiquitous mitochondrial creatine kinase is tissue-specific. Payne RM and Strauss AW, Biochim Biophys Acta. 1994 Sep 13;1219(1):33-8.
7. Structural characterization and tissue-specific expression of the mRNAs encoding isoenzymes from two rat mitochondrial creatine kinase genes. Payne RM, etal., Biochim Biophys Acta 1991 Jul 23;1089(3):352-61.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3338460   PMID:12477932   PMID:18614015   PMID:20833797   PMID:29867124  


Genomics

Comparative Map Data
Ckmt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2223,079,920 - 23,110,518 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl223,079,918 - 23,110,430 (-)Ensembl
Rnor_6.0221,422,680 - 21,452,797 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl221,422,818 - 21,437,193 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0240,627,924 - 40,657,402 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4222,084,948 - 22,106,014 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1222,005,331 - 22,026,403 (-)NCBI
Celera219,182,609 - 19,209,711 (-)NCBICelera
Cytogenetic Map2q12NCBI
CKMT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38581,233,322 - 81,266,398 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl581,233,320 - 81,266,398 (+)EnsemblGRCh38hg38GRCh38
GRCh37580,529,141 - 80,562,217 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36580,564,895 - 80,597,973 (+)NCBINCBI36hg18NCBI36
Build 34580,564,937 - 80,597,972NCBI
Celera576,433,409 - 76,466,487 (+)NCBI
Cytogenetic Map5q14.1NCBI
HuRef575,738,057 - 75,771,119 (+)NCBIHuRef
CHM1_1579,961,936 - 79,995,008 (+)NCBICHM1_1
T2T-CHM13v2.0581,717,903 - 81,750,979 (+)NCBI
Ckmt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391392,001,506 - 92,025,004 (-)NCBIGRCm39mm39
GRCm39 Ensembl1392,001,506 - 92,025,004 (-)Ensembl
GRCm381391,853,386 - 91,876,923 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1391,853,387 - 91,876,885 (-)EnsemblGRCm38mm10GRCm38
MGSCv371391,992,992 - 92,016,490 (-)NCBIGRCm37mm9NCBIm37
MGSCv361392,327,626 - 92,351,124 (-)NCBImm8
Celera1395,480,623 - 95,504,103 (-)NCBICelera
Cytogenetic Map13C3NCBI
Ckmt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541828,909,915 - 28,927,704 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541828,909,999 - 28,929,109 (-)NCBIChiLan1.0ChiLan1.0
CKMT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1534,324,529 - 34,357,963 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl534,324,529 - 34,356,919 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0534,013,387 - 34,046,522 (-)NCBIMhudiblu_PPA_v0panPan3
CKMT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1326,011,261 - 26,042,646 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl326,011,263 - 26,026,991 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha327,247,362 - 27,263,081 (-)NCBI
ROS_Cfam_1.0325,925,683 - 25,957,453 (-)NCBI
ROS_Cfam_1.0 Ensembl325,925,685 - 25,957,366 (-)Ensembl
UMICH_Zoey_3.1325,877,524 - 25,893,259 (-)NCBI
UNSW_CanFamBas_1.0325,847,135 - 25,862,863 (-)NCBI
UU_Cfam_GSD_1.0326,126,835 - 26,142,587 (-)NCBI
Ckmt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213182,027,158 - 182,049,174 (-)NCBI
SpeTri2.0NW_004936469575,836 - 598,601 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CKMT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl289,796,474 - 89,832,991 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1289,796,470 - 89,830,293 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2291,754,202 - 91,770,538 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2p16NCBI
CKMT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1475,379,181 - 75,414,640 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl475,398,939 - 75,414,715 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604924,253,413 - 24,288,192 (+)NCBIVero_WHO_p1.0
Ckmt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247431,791,423 - 1,812,970 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247431,791,040 - 1,812,970 (+)NCBIHetGla_female_1.0hetGla2


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
61368Mcs1Mammary carcinoma susceptibility QTL 14.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777223319447Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:108
Interacting mature miRNAs:113
Transcripts:ENSRNOT00000074008
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 7 3
Medium 22 2 2 2 8 8 2 8 8
Low 14 24 8 16 8 8 6 15 3
Below cutoff 1 4 4 2 4 14 12 21

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC158762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000084002   ⟹   ENSRNOP00000069574
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl223,079,920 - 23,110,430 (-)Ensembl
Rnor_6.0 Ensembl221,422,818 - 21,437,193 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111326   ⟹   ENSRNOP00000096397
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl223,079,920 - 23,110,430 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118630   ⟹   ENSRNOP00000089864
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl223,079,918 - 23,100,113 (-)Ensembl
RefSeq Acc Id: NM_001127652   ⟹   NP_001121124
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2223,079,920 - 23,110,387 (-)NCBI
Rnor_6.0221,422,680 - 21,452,797 (-)NCBI
Rnor_5.0240,627,924 - 40,657,402 (-)NCBI
RGSC_v3.4222,084,948 - 22,106,014 (-)RGD
Celera219,182,609 - 19,209,711 (-)RGD
Sequence:
RefSeq Acc Id: XM_039103157   ⟹   XP_038959085
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2223,079,920 - 23,110,518 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001121124 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959085 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58763 (Get FASTA)   NCBI Sequence Viewer  
  P09605 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001121124   ⟸   NM_001127652
- Peptide Label: precursor
- UniProtKB: B0BNC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069574   ⟸   ENSRNOT00000084002
RefSeq Acc Id: XP_038959085   ⟸   XM_039103157
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000096397   ⟸   ENSRNOT00000111326
RefSeq Acc Id: ENSRNOP00000089864   ⟸   ENSRNOT00000118630
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P09605-F1-model_v2 AlphaFold P09605 1-419 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61977 AgrOrtholog
BioCyc Gene G2FUF-54874 BioCyc
BioCyc Pathway PWY-6158 [creatine phosphate biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000055450 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000069574 ENTREZGENE
  ENSRNOP00000069574.2 UniProtKB/TrEMBL
  ENSRNOP00000089864.1 UniProtKB/TrEMBL
  ENSRNOP00000096397.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084002 ENTREZGENE
  ENSRNOT00000084002.2 UniProtKB/TrEMBL
  ENSRNOT00000111326.1 UniProtKB/TrEMBL
  ENSRNOT00000118630.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.135.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7105696 IMAGE-MGC_LOAD
InterPro ATP-guanido_PTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gln_synth/guanido_kin_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:688698 UniProtKB/TrEMBL
MGC_CLONE MGC:187999 IMAGE-MGC_LOAD
NCBI Gene 688698 ENTREZGENE
PANTHER PTHR11547 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ATP-gua_Ptrans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-gua_PtransN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ckmt2 PhenoGen
PROSITE PHOSPHAGEN_KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48034 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55931 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A864_RAT UniProtKB/TrEMBL
  A0A8I6AQI5_RAT UniProtKB/TrEMBL
  B0BNC0 ENTREZGENE, UniProtKB/TrEMBL
  KCRS_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0A0G2JVQ1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Ckmt2  creatine kinase, mitochondrial 2  Ckmt2  creatine kinase, mitochondrial 2, sarcomeric  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC688698  similar to creatine kinase, mitochondrial 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Ckmt2  creatine kinase, mitochondrial 2, sarcomeric      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed exclusively in skeletal muscle and heart 61552