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Gene: Ercc4 (ERCC excision repair 4, endonuclease catalytic subunit) Rattus norvegicus
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Symbol: Ercc4
Name: ERCC excision repair 4, endonuclease catalytic subunit
Description: Predicted to contribute to 3' overhang single-stranded DNA endodeoxyribonuclease activity and DNA binding activity. Involved in cellular response to organic cyclic compound. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group Q; XFE progeroid syndrome; pancreatic cancer; xeroderma pigmentosum; and xeroderma pigmentosum group F. Orthologous to human ERCC4 (ERCC excision repair 4, endonuclease catalytic subunit); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; INTERACTS WITH 3-aminobenzamide; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA repair endonuclease XPF; Ercc4 protein-like; excision repair cross-complementation group 4; excision repair cross-complementing rodent repair deficiency, complementation group 4; LOC304719; RGD1560340; similar to ERCC4_MOUSE
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0102,010,140 - 2,037,953 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010897,883 - 925,957 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4102,144,262 - 2,177,554NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ercc4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560340
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.