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Gene: RT1-DMa (RT1 class II, locus DMa) Rattus norvegicus
Symbol: RT1-DMa
Name: RT1 class II, locus DMa
RGD ID: 735053
Description: Predicted to have MHC class II protein complex binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; chaperone cofactor-dependent protein refolding; and positive regulation of immune response. Predicted to localize to several cellular components, including MHC class II protein complex; endosome; and lysosomal membrane. Orthologous to human HLA-DMA (major histocompatibility complex, class II, DM alpha); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane; alachlor.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DMA1; Hla-dma; major histocompatibility complex, class II, DM alpha; MHC class II-like alpha chain; RT1 class II, DM alpha; RT1.DMa; RT1.Ma
Is Marker For: Strains:   DA.E3-(RT1-DMa-Ggnbp1)   DA.KHW-(RT1-DMa-Mln)  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0203,935,512 - 3,938,915 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,240,975 - 5,244,386 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,302,036 - 7,305,439 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,843,458 - 4,846,861 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,843,691 - 4,847,054 (-)NCBI
Celera206,307,688 - 6,311,091 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on RT1-DMa
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735053
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.