Slc25a5 (solute carrier family 25 member 5) - Rat Genome Database
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Gene: Slc25a5 (solute carrier family 25 member 5) Rattus norvegicus
Analyze
Symbol: Slc25a5
Name: solute carrier family 25 member 5
RGD ID: 620353
Description: Predicted to have adenine nucleotide transmembrane transporter activity and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including adenine nucleotide transport; cellular response to leukemia inhibitory factor; and negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Localizes to membrane raft and mitochondrial inner membrane. Orthologous to human SLC25A5 (solute carrier family 25 member 5); PARTICIPATES IN calcium/calcium-mediated signaling pathway; Huntington's disease pathway; Parkinson's disease pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2,2-tetramine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Adenine nucleotid translocator 2 fibroblast isoform (ATP-ADP carrier protein); Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocator 2; adenine nucleotide translocator 2 fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocator 2, fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocator), member 5; ADP,ATP carrier protein 2; ADP/ATP translocase 2; ANT 2; Ant2; solute carrier family 25 (mitochondrial carrier; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
Orthologs:
Homo sapiens (human) : SLC25A5 (solute carrier family 25 member 5)  HGNC  Alliance
Mus musculus (house mouse) : Slc25a5 (solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc25a5 (solute carrier family 25 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC25A5 (solute carrier family 25 member 5)
Canis lupus familiaris (dog) : SLC25A5 (solute carrier family 25 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc25a5 (solute carrier family 25 member 5)
Sus scrofa (pig) : SLC25A5 (solute carrier family 25 member 5)
Chlorocebus sabaeus (African green monkey) : SLC25A5 (solute carrier family 25 member 5)
Heterocephalus glaber (naked mole-rat) : Slc25a5 (solute carrier family 25 member 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X123,404,570 - 123,407,637 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,404,518 - 123,407,645 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X123,549,736 - 123,552,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X8,072,239 - 8,075,306 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X8,077,794 - 8,080,862 (-)NCBI
CeleraX115,261,785 - 115,264,852 (+)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12865426   PMID:14651853   PMID:15489334   PMID:17634366   PMID:18063578   PMID:18614015   PMID:19116139   PMID:19154410   PMID:19725078   PMID:19946888   PMID:20439489   PMID:20797633  
PMID:20833797   PMID:21630459   PMID:22658674   PMID:23106098   PMID:23267836   PMID:23376485   PMID:23979707   PMID:24625528   PMID:26316108   PMID:27458020   PMID:28376086   PMID:29476059  


Genomics

Comparative Map Data
Slc25a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X123,404,570 - 123,407,637 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,404,518 - 123,407,645 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X123,549,736 - 123,552,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X8,072,239 - 8,075,306 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X8,077,794 - 8,080,862 (-)NCBI
CeleraX115,261,785 - 115,264,852 (+)NCBICelera
Cytogenetic MapXq35NCBI
SLC25A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX119,468,422 - 119,471,396 (+)EnsemblGRCh38hg38GRCh38
GRCh38X119,468,444 - 119,471,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X118,602,363 - 118,605,359 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,486,433 - 118,489,320 (+)NCBINCBI36hg18NCBI36
Build 34X118,384,290 - 118,387,161NCBI
CeleraX119,057,070 - 119,060,067 (+)NCBI
Cytogenetic MapXq24NCBI
HuRefX108,095,551 - 108,098,548 (+)NCBIHuRef
CHM1_1X118,513,525 - 118,516,522 (+)NCBICHM1_1
Slc25a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X36,059,250 - 36,062,461 (+)NCBI
GRCm38X36,795,597 - 36,798,808 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX36,795,651 - 36,798,807 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X34,335,647 - 34,338,801 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X33,227,097 - 33,230,251 (+)NCBImm8
CeleraX23,519,362 - 23,522,516 (+)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX21.2NCBI
Slc25a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955534496,933 - 510,934 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955534497,518 - 500,309 (-)NCBIChiLan1.0ChiLan1.0
SLC25A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X118,926,743 - 118,929,632 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX118,926,743 - 118,929,624 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X108,501,654 - 108,504,591 (+)NCBIMhudiblu_PPA_v0panPan3
SLC25A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX91,523,643 - 91,526,479 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X91,523,649 - 91,526,447 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc25a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647910,432,172 - 10,435,154 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX97,919,290 - 97,922,245 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X97,919,295 - 97,922,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X113,743,301 - 113,746,201 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A5
(Chlorocebus sabaeus - African green monkey)
No map positions available.
Slc25a5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248953,472,810 - 3,475,713 (+)NCBI

Position Markers
Slc25a5  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01219,748,511 - 219,749,554NCBIRnor6.0
Rnor_5.01226,616,169 - 226,617,212UniSTSRnor5.0
Celera1199,332,552 - 199,333,595UniSTS
Cytogenetic Map1q42UniSTS
Cytogenetic MapXq36UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X70352120127888215Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X82930791127930791Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X101333032146333032Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX107886746152409805Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X110957467155957467Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X110957467155957467Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118715462159970021Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX120045041143145818Rat
5685004Bss104Bone structure and strength QTL 1043.9tibia area (VT:1000281)tibia area measurement (CMO:0001382)X121442246134627946Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:183
Count of miRNA genes:143
Interacting mature miRNAs:166
Transcripts:ENSRNOT00000015085
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 7 6
Medium 2 43 57 41 19 41 8 11 74 29 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_057102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AABR07041236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01113925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000015085   ⟹   ENSRNOP00000015913
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX123,404,518 - 123,407,645 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092523
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX123,406,485 - 123,407,488 (+)Ensembl
RefSeq Acc Id: NM_057102   ⟹   NP_476443
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X123,404,570 - 123,407,637 (+)NCBI
Rnor_5.0X123,549,736 - 123,552,803 (+)NCBI
RGSC_v3.4X8,072,239 - 8,075,306 (-)RGD
CeleraX115,261,785 - 115,264,852 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_476443 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH59108 (Get FASTA)   NCBI Sequence Viewer  
  BAA02238 (Get FASTA)   NCBI Sequence Viewer  
  EDM10821 (Get FASTA)   NCBI Sequence Viewer  
  Q09073 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_476443   ⟸   NM_057102
- UniProtKB: Q09073 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000015913   ⟸   ENSRNOT00000015085

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701983
Promoter ID:EPDNEW_R12506
Type:multiple initiation site
Name:Slc25a5_1
Description:solute carrier family 25 member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X123,404,537 - 123,404,597EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
X 123550909 123550910 A C snv BDIX.Cg-Tal/NemOda (KyushuU), BDIX/NemOda (KyushuU)
X 123550915 123550916 C T snv HWY/Slc (KyushuU), DOB/Oda (KyushuU)
X 123551074 123551075 T A snv SS/JrHsdMcwi (MCW), IS/Kyo (KyushuU), NIG-III/Hok (KyushuU), F344/DuCrlCrlj (KyushuU), LE/Stm (KyushuU), HTX/Kyo (KyushuU), F344/NSlc (KyushuU), RCS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), F344/Stm (KyushuU), HWY/Slc (KyushuU), LEC/Tj (KyushuU), BDIX/NemOda (KyushuU), DOB/Oda (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), SR/JrHsd (MCW), SBN/Ygl (MCW), ZFDM (KyushuU), GH/OmrMcwi (MCW), SBH/Ygl (MCW), ZF (KyushuU)
X 123551110 123551111 G A snv ZF (KyushuU)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
X 123405790 123405791 A G snv M520/N (MCW)
X 123405905 123405906 A G snv WKY/N (MCW)
X 123405908 123405909 T A snv SS/JrHsdMcwi (MCW), CDS


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
X 8073968 8073969 A T snv SHR/OlaIpcv (KNAW), SS/JrHsdMcwi (MCW), SS/JrHsdMcwi (MDC), GH/OmrMcwi (MCW), SR/JrHsd (MCW)
X 8073969 8073970 A G snv WKY/N (KNAW), SHRSP/Gcrc (MDC)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620353 AgrOrtholog
Ensembl Genes ENSRNOG00000039980 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000015913 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015085 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.50.40.10 UniProtKB/Swiss-Prot
InterPro Aden_trnslctor UniProtKB/Swiss-Prot
  Mit_carrier UniProtKB/Swiss-Prot
  Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:25176 UniProtKB/Swiss-Prot
NCBI Gene 25176 ENTREZGENE
Pfam Mito_carr UniProtKB/Swiss-Prot
PhenoGen Slc25a5 PhenoGen
PRINTS ADPTRNSLCASE UniProtKB/Swiss-Prot
  MITOCARRIER UniProtKB/Swiss-Prot
PROSITE SOLCAR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot
UniGene Rn.102263 ENTREZGENE
UniProt ADT2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Slc25a5  solute carrier family 25 member 5  Slc25a5  solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Slc25a5  solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5      Symbol and Name updated 629477 APPROVED
2003-03-06 Slc25a5  solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5  Ant2  Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein)  Data Merged 628472 PROVISIONAL
2002-08-07 Slc25a5        Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Ant2  Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein)      Symbol and Name status set to approved 70586 APPROVED