Gfm1 (G elongation factor, mitochondrial 1) - Rat Genome Database

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Gene: Gfm1 (G elongation factor, mitochondrial 1) Rattus norvegicus
Analyze
Symbol: Gfm1
Name: G elongation factor, mitochondrial 1
RGD ID: 631396
Description: Predicted to enable GTPase activity and translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 1. Orthologous to human GFM1 (G elongation factor mitochondrial 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EF-G; EF-Gmt; Efg; elongation factor G 1, mitochondrial; elongation factor G, mitochondrial; elongation factor G1; G elongation factor; Gfm; mEF-G 1; MGC93294; mitochondrial elongation factor G
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22151,700,573 - 151,745,477 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2151,700,564 - 151,745,471 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2158,817,201 - 158,861,971 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02156,867,699 - 156,912,472 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02151,500,450 - 151,545,218 (+)NCBIRnor_WKY
Rnor_6.02164,601,575 - 164,646,478 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2164,601,586 - 164,646,439 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02183,950,902 - 183,995,881 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42157,283,046 - 157,327,969 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12157,233,008 - 157,277,932 (+)NCBI
Celera2146,070,110 - 146,114,990 (+)NCBICelera
Cytogenetic Map2q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrion  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Identification of the gene encoding the mitochondrial elongation factor G in mammals. Barker C, etal., Nucleic Acids Res 1993 Jun 11;21(11):2641-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14651853   PMID:18614015   PMID:19716793   PMID:22658674   PMID:26316108  


Genomics

Comparative Map Data
Gfm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22151,700,573 - 151,745,477 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2151,700,564 - 151,745,471 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2158,817,201 - 158,861,971 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02156,867,699 - 156,912,472 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02151,500,450 - 151,545,218 (+)NCBIRnor_WKY
Rnor_6.02164,601,575 - 164,646,478 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2164,601,586 - 164,646,439 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02183,950,902 - 183,995,881 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42157,283,046 - 157,327,969 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12157,233,008 - 157,277,932 (+)NCBI
Celera2146,070,110 - 146,114,990 (+)NCBICelera
Cytogenetic Map2q32NCBI
GFM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383158,644,527 - 158,695,581 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3158,644,527 - 158,695,581 (+)EnsemblGRCh38hg38GRCh38
GRCh373158,362,316 - 158,413,370 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363159,845,011 - 159,893,055 (+)NCBINCBI36Build 36hg18NCBI36
Celera3156,784,902 - 156,832,946 (+)NCBICelera
Cytogenetic Map3q25.32NCBI
HuRef3155,758,163 - 155,806,206 (+)NCBIHuRef
CHM1_13158,325,291 - 158,373,337 (+)NCBICHM1_1
T2T-CHM13v2.03161,418,448 - 161,469,504 (+)NCBIT2T-CHM13v2.0
Gfm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39367,337,448 - 67,382,401 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl367,337,429 - 67,383,862 (+)EnsemblGRCm39 Ensembl
GRCm38367,430,115 - 67,475,068 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl367,430,096 - 67,476,529 (+)EnsemblGRCm38mm10GRCm38
MGSCv37367,234,037 - 67,278,990 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36367,518,044 - 67,562,997 (+)NCBIMGSCv36mm8
Celera367,556,209 - 67,601,175 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.96NCBI
Gfm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554489,390,576 - 9,433,404 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554489,390,576 - 9,432,919 (+)NCBIChiLan1.0ChiLan1.0
GFM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13163,721,473 - 163,769,454 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3163,721,479 - 163,769,454 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03155,670,432 - 155,721,404 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GFM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12351,940,307 - 51,983,196 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2351,940,071 - 51,982,636 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2351,749,477 - 51,792,992 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02352,580,688 - 52,624,233 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2352,580,668 - 52,624,232 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12352,161,073 - 52,204,519 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02352,213,985 - 52,257,486 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02352,499,435 - 52,542,963 (+)NCBIUU_Cfam_GSD_1.0
Gfm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560284,441,526 - 84,489,184 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365195,244,591 - 5,292,439 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365195,245,202 - 5,292,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1398,411,179 - 98,458,525 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11398,411,132 - 98,456,496 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213106,704,037 - 106,749,956 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GFM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11532,153,650 - 32,198,393 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1532,150,607 - 32,198,396 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660414,716,825 - 4,761,563 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473036,354,255 - 36,400,195 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473036,354,334 - 36,400,999 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gfm1
314 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:23
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000017608, ENSRNOT00000042079
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1354594Despr10Despair related QTL 100.00000249locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2114654253159654253Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1582257Gluco21Glucose level QTL 213.10.0035blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2118111229157142209Rat
738007Anxrr7Anxiety related response QTL 74.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2118189491163189491Rat
1358360Sradr2Stress Responsive Adrenal Weight QTL 210.24adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)2129164097152195315Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631520Bp73Blood pressure QTL 730.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147686913168355276Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat

Markers in Region
RH129668  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22151,727,560 - 151,727,742 (+)MAPPERmRatBN7.2
Rnor_6.02164,628,570 - 164,628,751NCBIRnor6.0
Rnor_5.02183,977,973 - 183,978,154UniSTSRnor5.0
RGSC_v3.42157,310,041 - 157,310,222UniSTSRGSC3.4
Celera2146,097,082 - 146,097,263UniSTS
RH 3.4 Map2995.7UniSTS
Cytogenetic Map2q31UniSTS
RH129902  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22151,727,636 - 151,727,835 (+)MAPPERmRatBN7.2
Rnor_6.02164,628,646 - 164,628,844NCBIRnor6.0
Rnor_5.02183,978,049 - 183,978,247UniSTSRnor5.0
RGSC_v3.42157,310,117 - 157,310,315UniSTSRGSC3.4
Celera2146,097,158 - 146,097,356UniSTS
RH 3.4 Map2995.8UniSTS
Cytogenetic Map2q31UniSTS
BE104714  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22151,737,056 - 151,737,224 (+)MAPPERmRatBN7.2
Rnor_6.02164,638,065 - 164,638,232NCBIRnor6.0
Rnor_5.02183,987,468 - 183,987,635UniSTSRnor5.0
RGSC_v3.42157,319,536 - 157,319,703UniSTSRGSC3.4
Celera2146,106,577 - 146,106,744UniSTS
RH 3.4 Map2995.8UniSTS
Cytogenetic Map2q31UniSTS
RH138806  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22151,730,685 - 151,730,845 (+)MAPPERmRatBN7.2
Rnor_6.02164,631,695 - 164,631,854NCBIRnor6.0
Rnor_5.02183,981,098 - 183,981,257UniSTSRnor5.0
RGSC_v3.42157,313,166 - 157,313,325UniSTSRGSC3.4
Celera2146,100,207 - 146,100,366UniSTS
RH 3.4 Map2995.8UniSTS
Cytogenetic Map2q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 40 11 8
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000017608   ⟹   ENSRNOP00000017608
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2164,601,712 - 164,646,258 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000042079   ⟹   ENSRNOP00000040081
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2151,700,564 - 151,745,471 (+)Ensembl
Rnor_6.0 Ensembl2164,601,586 - 164,646,439 (+)Ensembl
RefSeq Acc Id: NM_053625   ⟹   NP_446077
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22151,700,573 - 151,745,477 (+)NCBI
Rnor_6.02164,601,575 - 164,646,478 (+)NCBI
Rnor_5.02183,950,902 - 183,995,881 (+)NCBI
RGSC_v3.42157,283,046 - 157,327,969 (+)RGD
Celera2146,070,110 - 146,114,990 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446077 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41107 (Get FASTA)   NCBI Sequence Viewer  
  AAH85721 (Get FASTA)   NCBI Sequence Viewer  
  EDM00923 (Get FASTA)   NCBI Sequence Viewer  
  Q07803 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_446077   ⟸   NM_053625
- UniProtKB: Q5U347 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000040081   ⟸   ENSRNOT00000042079
RefSeq Acc Id: ENSRNOP00000017608   ⟸   ENSRNOT00000017608
Protein Domains
tr-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q07803-F1-model_v2 AlphaFold Q07803 1-751 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691365
Promoter ID:EPDNEW_R1890
Type:initiation region
Name:Gfm1_1
Description:G elongation factor, mitochondrial 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02164,601,589 - 164,601,649EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631396 AgrOrtholog
BioCyc Gene G2FUF-52866 BioCyc
Ensembl Genes ENSRNOG00000012873 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000040081 ENTREZGENE
  ENSRNOP00000040081.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042079 ENTREZGENE
  ENSRNOT00000042079.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.230.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192461 IMAGE-MGC_LOAD
InterPro EFG1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_III/V UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_V UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_V-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFTu-like_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_TR_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold_subgr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T_Tr_GTP-bd_dom UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  Transl_B-barrel_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_EFG/EF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_EFG/EF2_IV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:114017 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93294 IMAGE-MGC_LOAD
NCBI Gene 114017 ENTREZGENE
PANTHER PTHR43636 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EFG_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_IV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gfm1 PhenoGen
PRINTS ELONGATNFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_TR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_TR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EFG_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_IV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54211 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54980 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs EF-G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  small_GTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2ULJ1_RAT UniProtKB/TrEMBL
  EFGM_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5U347 ENTREZGENE
UniProt Secondary Q5U347 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-25 Gfm1  G elongation factor, mitochondrial 1  Gfm  G elongation factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Gfm  G elongation factor  Efg    Symbol updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in all tissues, enriched in liver, thymus and brain 632613
gene_homology 62% and 61% homology to the Thermus thermophilus and E. coli elongation factor-G (EF-G) respectively; 52% homology to the rat elongation factor-2 (EF-2) 632613
gene_protein 752 amino acid 632613