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Gene: Map1lc3a (microtubule-associated protein 1 light chain 3 alpha) Rattus norvegicus
Symbol: Map1lc3a
Name: microtubule-associated protein 1 light chain 3 alpha
RGD ID: 735183
Description: Predicted to have microtubule binding activity; phosphatidylethanolamine binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to copper ion; cellular response to hydrogen peroxide; and response to morphine. Localizes to several cellular components, including autophagosome membrane; cytosol; and late endosome. Biomarker of several diseases, including artery disease (multiple); degenerative disc disease; ischemia (multiple); retinal detachment; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in glioblastoma multiforme. Orthologous to human MAP1LC3A (microtubule associated protein 1 light chain 3 alpha); PARTICIPATES IN autophagy pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: autophagy-related protein LC3 A; autophagy-related ubiquitin-like modifier LC3 A; LC3-I; LC3-II; LC3A; MAP1 light chain 3-like protein 1; MAP1A/1B light chain 3 A; MAP1A/MAP1B LC3 A; MAP1A/MAP1B light chain 3 A; MGC105263; microtubule-associated proteins 1A/1B light chain 3A
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03150,801,289 - 150,802,935 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3150,801,289 - 150,802,935 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,169,534 - 157,171,180 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43145,758,939 - 145,760,532 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13145,664,573 - 145,666,154 (+)NCBI
Celera3142,510,304 - 142,511,947 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Map1lc3a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735183
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.