Map1lc3b (microtubule-associated protein 1 light chain 3 beta) - Rat Genome Database

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Gene: Map1lc3b (microtubule-associated protein 1 light chain 3 beta) Rattus norvegicus
Analyze
Symbol: Map1lc3b
Name: microtubule-associated protein 1 light chain 3 beta
RGD ID: 621315
Description: Enables microtubule binding activity and protein domain specific binding activity. Involved in positive regulation of protein binding activity. Located in several cellular components, including autophagosome membrane; dendrite; and neuronal cell body. Part of microtubule associated complex. Orthologous to several human genes including MAP1LC3B (microtubule associated protein 1 light chain 3 beta); PARTICIPATES IN autophagy pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: autophagy-related protein LC3 B; autophagy-related ubiquitin-like modifier LC3 B; LC3B; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; Map1lc3; MGC93422; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3B; MPL3; zbs559
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21949,665,795 - 49,673,655 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1949,665,791 - 49,677,690 (+)Ensembl
Rnor_6.01953,635,449 - 53,643,970 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1953,629,779 - 53,646,058 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01964,373,068 - 64,381,400 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41951,847,187 - 51,854,858 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11951,852,067 - 51,859,738 (+)NCBI
Celera1948,912,797 - 48,920,467 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Tetrandrine  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP,ISO)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-D  (EXP)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxyethyl methacrylate  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP,ISO)
3-methyladenine  (EXP,ISO)
3-Nitrofluoranthene  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-methoxy-TEMPO  (ISO)
4-phenylbutyric acid  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
7-ketocholesterol  (ISO)
abamectin  (EXP)
ABT-737  (ISO)
acadesine  (ISO)
acetaldehyde  (ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
aldrin  (ISO)
alginic acid  (ISO)
all-trans-retinoic acid  (ISO)
aloxistatin  (ISO)
alpha,alpha-trehalose  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP,ISO)
amphotericin B  (ISO)
antimycin A  (ISO)
apigenin  (ISO)
apocynin  (EXP)
aristolochic acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
atazanavir sulfate  (ISO)
atrazine  (ISO)
auramine O  (ISO)
AZD4547  (ISO)
bafilomycin A1  (EXP,ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
betulinic acid  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
bortezomib  (ISO)
brefeldin A  (ISO)
buspirone  (EXP)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcidiol  (ISO)
calix[6]arene  (ISO)
Calpeptin  (ISO)
carbon disulfide  (ISO)
carbon nanotube  (EXP,ISO)
carglumic acid  (ISO)
celecoxib  (ISO)
CGS-21680  (ISO)
chenodeoxycholic acid  (ISO)
chloropicrin  (ISO)
chloroquine  (EXP,ISO)
chlorpyrifos  (EXP)
cholesterol  (ISO)
cholic acid  (ISO)
chromium(6+)  (ISO)
chrysin  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
Citreoviridin  (EXP,ISO)
clobetasol  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
colistin  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cryptotanshinone  (ISO)
Curcumol  (EXP)
cyanamide  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
D-mannopyranose  (ISO)
DDE  (ISO)
deguelin  (ISO)
Dehydroeburicoic acid  (ISO)
deoxycholic acid  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenzofuran  (ISO)
dibutyl phthalate  (EXP,ISO)
diosgenin  (EXP,ISO)
dioxygen  (ISO)
diquat  (ISO)
disodium selenite  (EXP,ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
enzalutamide  (ISO)
erastin  (EXP)
erlotinib hydrochloride  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
everolimus  (ISO)
ferric oxide  (ISO)
finasteride  (EXP)
flavokawain B  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fomepizole  (ISO)
formaldehyde  (EXP,ISO)
gamma-hexachlorocyclohexane  (EXP)
gingerol  (ISO)
ginsenoside Rg2  (ISO)
glafenine  (EXP)
glucose  (EXP)
glutathione  (EXP,ISO)
glycerol 2-phosphate  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhizinic acid  (EXP)
hesperidin  (EXP)
hexadecanoic acid  (EXP,ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (ISO)
indoxyl sulfate  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
ivermectin  (ISO)
juglone  (ISO)
kainic acid  (EXP)
L-ascorbic acid 2-phosphate  (ISO)
L-leucine  (ISO)
L-serine  (EXP)
lactulose  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (EXP,ISO)
levofloxacin  (ISO)
lipopolysaccharide  (EXP)
luteolin  (ISO)
LY294002  (EXP)
melatonin  (ISO)
melibiose  (ISO)
menadione  (ISO)
metformin  (ISO)
methamphetamine  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (ISO)
metyrapone  (ISO)
miconazole  (ISO)
myriocin  (ISO)
N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-acylsphinganine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
NADP zwitterion  (EXP)
NADP(+)  (EXP)
Naftopidil  (ISO)
nefazodone  (EXP,ISO)
nelfinavir  (ISO)
niclosamide  (ISO)
nicotinamide  (ISO)
nimesulide  (EXP)
Nonylphenol  (EXP)
obeticholic acid  (ISO)
oleanolic acid  (ISO)
oleic acid  (ISO)
oxidopamine  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PD 0325901  (ISO)
Pentoxifylline  (EXP)
pepstatin A  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perfluoroundecanoic acid  (EXP)
phenobarbital  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidylethanolamine  (ISO)
pirinixic acid  (ISO)
platycodin D  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
procyanidin B2  (ISO)
quercetin  (ISO)
quetiapine fumarate  (ISO)
radon atom  (ISO)
radon(0)  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rimonabant  (ISO)
rotenone  (EXP,ISO)
roxadustat  (EXP)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sirolimus  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
Soman  (EXP)
spironolactone  (EXP)
sulforaphane  (ISO)
sulfur dioxide  (EXP)
T-2 toxin  (EXP)
tamoxifen  (ISO)
taurine  (ISO)
taurocholic acid  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thapsigargin  (EXP,ISO)
thiamine(1+) chloride  (EXP,ISO)
thifluzamide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
trichostatin A  (EXP,ISO)
trifloxystrobin  (ISO)
trimethyltin  (EXP)
trovafloxacin  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (EXP)
vinclozolin  (EXP)
vincristine  (ISO)
vismodegib  (ISO)
vorinostat  (EXP,ISO)
wortmannin  (ISO)
zearalenone  (EXP,ISO)
zinc atom  (ISO)
zinc oxide  (EXP,ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:11060023   PMID:14760703   PMID:15095872   PMID:15489334   PMID:16854843   PMID:19279012   PMID:22783020   PMID:22948227   PMID:23629966   PMID:24089209   PMID:24185898   PMID:24351649  
PMID:24747438   PMID:25127057   PMID:25215947   PMID:25244949   PMID:25494214   PMID:26284655   PMID:27187184   PMID:27442348   PMID:28223137   PMID:29554128   PMID:29901175   PMID:31140414  
PMID:33391467  


Genomics

Comparative Map Data
Map1lc3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21949,665,795 - 49,673,655 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1949,665,791 - 49,677,690 (+)Ensembl
Rnor_6.01953,635,449 - 53,643,970 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1953,629,779 - 53,646,058 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01964,373,068 - 64,381,400 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41951,847,187 - 51,854,858 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11951,852,067 - 51,859,738 (+)NCBI
Celera1948,912,797 - 48,920,467 (+)NCBICelera
Cytogenetic Map19q12NCBI
MAP1LC3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381687,392,336 - 87,404,774 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1687,383,953 - 87,404,779 (+)EnsemblGRCh38hg38GRCh38
GRCh371687,425,942 - 87,438,380 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361685,983,320 - 85,995,881 (+)NCBINCBI36hg18NCBI36
Build 341685,983,450 - 85,995,880NCBI
Celera1671,722,569 - 71,735,146 (+)NCBI
Cytogenetic Map16q24.2NCBI
HuRef1673,168,889 - 73,180,793 (+)NCBIHuRef
CHM1_11688,837,611 - 88,850,167 (+)NCBICHM1_1
Map1lc3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398122,317,177 - 122,325,499 (+)NCBIGRCm39mm39
GRCm39 Ensembl8122,317,100 - 122,325,499 (+)Ensembl
GRCm388121,590,438 - 121,598,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8121,590,361 - 121,598,760 (+)EnsemblGRCm38mm10GRCm38
MGSCv378124,114,368 - 124,121,947 (+)NCBIGRCm37mm9NCBIm37
MGSCv368124,476,528 - 124,484,107 (+)NCBImm8
Celera8125,811,811 - 125,819,390 (+)NCBICelera
Cytogenetic Map8E1NCBI
Map1lc3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555411,852,388 - 1,868,194 (+)NCBIChiLan1.0ChiLan1.0
MAP1LC3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11687,393,976 - 87,399,736 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01668,063,869 - 68,076,772 (+)NCBIMhudiblu_PPA_v0panPan3
MAP1LC3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1565,669,553 - 65,683,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha565,681,248 - 65,695,108 (-)NCBI
ROS_Cfam_1.0565,891,103 - 65,905,466 (-)NCBI
UMICH_Zoey_3.1565,915,961 - 65,929,771 (-)NCBI
UNSW_CanFamBas_1.0565,747,849 - 65,761,805 (-)NCBI
UU_Cfam_GSD_1.0566,161,995 - 66,175,961 (-)NCBI
MAP1LC3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,915,387 - 1,941,077 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.161,919,879 - 1,941,069 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.262,007,809 - 2,029,003 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAP1LC3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1572,762,428 - 72,774,204 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl572,763,050 - 72,772,770 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660472,921,927 - 2,933,888 (-)NCBIVero_WHO_p1.0
Map1lc3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247463,084,418 - 3,094,250 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH128740  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21949,673,499 - 49,673,652 (+)MAPPERmRatBN7.2
Rnor_6.01953,643,815 - 53,643,967NCBIRnor6.0
Rnor_5.01964,381,250 - 64,381,402UniSTSRnor5.0
RGSC_v3.41951,854,708 - 51,854,860UniSTSRGSC3.4
Celera1948,920,317 - 48,920,469UniSTS
RH 3.4 Map19680.7UniSTS
Cytogenetic Map19q12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:288
Count of miRNA genes:193
Interacting mature miRNAs:226
Transcripts:ENSRNOT00000051352, ENSRNOT00000067141
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000051352   ⟹   ENSRNOP00000049421
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1953,629,779 - 53,646,055 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000067141   ⟹   ENSRNOP00000062130
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1949,665,984 - 49,677,690 (+)Ensembl
Rnor_6.0 Ensembl1953,635,688 - 53,643,964 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079382   ⟹   ENSRNOP00000072338
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1949,665,791 - 49,675,743 (+)Ensembl
Rnor_6.0 Ensembl1953,635,445 - 53,646,058 (+)Ensembl
RefSeq Acc Id: NM_022867   ⟹   NP_074058
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21949,665,979 - 49,673,650 (+)NCBI
Rnor_6.01953,635,633 - 53,643,965 (+)NCBI
Rnor_5.01964,373,068 - 64,381,400 (+)NCBI
RGSC_v3.41951,847,187 - 51,854,858 (+)RGD
Celera1948,912,797 - 48,920,467 (+)RGD
Sequence:
RefSeq Acc Id: XM_017601351   ⟹   XP_017456840
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21949,665,795 - 49,673,655 (+)NCBI
Rnor_6.01953,635,449 - 53,643,970 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_074058   ⟸   NM_022867
- UniProtKB: Q62625 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017456840   ⟸   XM_017601351
- Peptide Label: isoform X1
- UniProtKB: Q62625 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072338   ⟸   ENSRNOT00000079382
RefSeq Acc Id: ENSRNOP00000062130   ⟸   ENSRNOT00000067141
RefSeq Acc Id: ENSRNOP00000049421   ⟸   ENSRNOT00000051352

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62625-F1-model_v2 AlphaFold Q62625 1-142 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701192
Promoter ID:EPDNEW_R11715
Type:initiation region
Name:Map1lc3b_1
Description:microtubule-associated protein 1 light chain 3 beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01953,635,650 - 53,635,710EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621315 AgrOrtholog
BioCyc Gene G2FUF-5427 BioCyc
Ensembl Genes ENSRNOG00000017905 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000049421 UniProtKB/TrEMBL
  ENSRNOP00000062130 UniProtKB/Swiss-Prot
  ENSRNOP00000072338 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000051352 UniProtKB/TrEMBL
  ENSRNOT00000067141 UniProtKB/Swiss-Prot
  ENSRNOT00000079382 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6889616 IMAGE-MGC_LOAD
  IMAGE:7189855 IMAGE-MGC_LOAD
InterPro Atg8-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64862 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72811 IMAGE-MGC_LOAD
  MGC:93422 IMAGE-MGC_LOAD
NCBI Gene 64862 ENTREZGENE
PANTHER PTHR10969 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Atg8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Map1lc3b PhenoGen
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt MLP3B_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q7TQ75_RAT UniProtKB/TrEMBL
UniProt Secondary Q6XVN7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Map1lc3b  microtubule-associated protein 1 light chain 3 beta    microtubule-associated proteins 1A/1B light chain 3  Name updated 1299863 APPROVED
2004-09-10 Map1lc3b  microtubule-associated proteins 1A/1B light chain 3  MPL3    Symbol and Name updated 1299863 APPROVED
2002-08-07 MPL3  microtubule-associated proteins 1A/1B light chain 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed only in neurons 633201
gene_protein 16.4 kDa 633201