Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | increases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of SH3GLB1 mRNA | CTD | PMID:26682919 | 17alpha-ethynylestradiol | multiple interactions | ISO | Sh3glb1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SH3GLB1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Estradiol results in decreased expression of SH3GLB1 mRNA | CTD | PMID:22467019 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of SH3GLB1 protein | CTD | PMID:32145629 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Sh3glb1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SH3GLB1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SH3GLB1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SH3GLB1 mRNA | CTD | PMID:21570461 | 2,4,6-tribromophenol | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of SH3GLB1 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of SH3GLB1 mRNA | CTD | PMID:30851411 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of SH3GLB1 protein | CTD | PMID:31675489 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of SH3GLB1 mRNA | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | decreases methylation | ISO | Sh3glb1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased methylation of SH3GLB1 promoter | CTD | PMID:26251327 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Sh3glb1 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of SH3GLB1 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of SH3GLB1 protein | CTD | PMID:34186270 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of SH3GLB1 mRNA | CTD | PMID:28973697 | aflatoxin B1 | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of SH3GLB1 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SH3GLB1 mRNA | CTD | PMID:23724009 | antirheumatic drug | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of SH3GLB1 mRNA | CTD | PMID:24449571 | Aroclor 1254 | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of SH3GLB1 mRNA | CTD | PMID:23650126 | atazanavir sulfate | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Atazanavir Sulfate results in increased expression of SH3GLB1 mRNA | CTD | PMID:32152650 | atazanavir sulfate | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA | CTD | PMID:32152650 | benzo[a]pyrene | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SH3GLB1 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SH3GLB1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SH3GLB1 mRNA | CTD | PMID:26238291 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SH3GLB1 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SH3GLB1 protein | CTD | PMID:34186270 | bisphenol A | decreases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SH3GLB1 protein | CTD | PMID:31675489 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SH3GLB1 mRNA and bisphenol A results in decreased expression of SH3GLB1 protein | CTD | PMID:32145629 and PMID:34947998 | bisphenol A | decreases methylation | ISO | Sh3glb1 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of SH3GLB1 promoter | CTD | PMID:27312807 | Bisphenol B | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of SH3GLB1 protein | CTD | PMID:34186270 | calcitriol | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of SH3GLB1 mRNA | CTD | PMID:21592394 | calcitriol | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of SH3GLB1 mRNA | CTD | PMID:21592394 | carbamazepine | affects expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of SH3GLB1 mRNA | CTD | PMID:24752500 | chenodeoxycholic acid | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA more ... | CTD | PMID:32152650 | cisplatin | increases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Cisplatin results in increased expression of SH3GLB1 mRNA | CTD | PMID:21151649 | clofibrate | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of SH3GLB1 mRNA | CTD | PMID:17585979 | cobalt dichloride | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of SH3GLB1 mRNA | CTD | PMID:19376846 | copper(II) sulfate | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SH3GLB1 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of SH3GLB1 mRNA | CTD | PMID:19770486 | cyclosporin A | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA | CTD | PMID:32152650 | cyclosporin A | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SH3GLB1 mRNA | CTD | PMID:20106945 more ... | decabromodiphenyl ether | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of SH3GLB1 protein | CTD | PMID:31675489 | deguelin | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | deguelin results in increased expression of SH3GLB1 mRNA | CTD | PMID:33512557 | deoxycholic acid | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA more ... | CTD | PMID:32152650 | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of SH3GLB1 mRNA | CTD | PMID:22546817 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of SH3GLB1 mRNA | CTD | PMID:21266533 | diclofenac | affects expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Diclofenac affects the expression of SH3GLB1 mRNA | CTD | PMID:24752500 | dioxygen | increases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of SH3GLB1 mRNA | CTD | PMID:22629407 | dioxygen | multiple interactions | ISO | Sh3glb1 (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of SH3GLB1 mRNA] | CTD | PMID:22629407 | doxorubicin | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of SH3GLB1 mRNA | CTD | PMID:26873546 | doxorubicin | affects expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of SH3GLB1 protein | CTD | PMID:29385562 | enniatin | decreases expression | EXP | | 6480464 | enniatins results in decreased expression of SH3GLB1 mRNA | CTD | PMID:27163883 | enzyme inhibitor | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SH3GLB1 protein | CTD | PMID:23301498 | epoxiconazole | increases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of SH3GLB1 mRNA | CTD | PMID:35436446 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of SH3GLB1 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SH3GLB1 mRNA | CTD | PMID:25629700 | glycochenodeoxycholic acid | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA more ... | CTD | PMID:32152650 | glycocholic acid | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA more ... | CTD | PMID:32152650 | glycodeoxycholic acid | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA more ... | CTD | PMID:32152650 | ivermectin | decreases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SH3GLB1 protein | CTD | PMID:32959892 | leflunomide | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | leflunomide results in increased expression of SH3GLB1 mRNA | CTD | PMID:28988120 and PMID:29427785 | Mesaconitine | decreases expression | EXP | | 6480464 | mesaconitine results in decreased expression of SH3GLB1 protein | CTD | PMID:37182599 | methyl methanesulfonate | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of SH3GLB1 mRNA | CTD | PMID:23649840 | nefazodone | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | nefazodone results in increased expression of SH3GLB1 mRNA | CTD | PMID:32152650 | nefazodone | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA | CTD | PMID:32152650 | oxybenzone | increases expression | EXP | | 6480464 | oxybenzone results in increased expression of SH3GLB1 mRNA | CTD | PMID:30316929 | paracetamol | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SH3GLB1 mRNA | CTD | PMID:25704631 and PMID:29067470 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Sh3glb1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of SH3GLB1 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of SH3GLB1 protein | CTD | PMID:26879310 | phenobarbital | affects expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of SH3GLB1 mRNA | CTD | PMID:19159669 | phenylmercury acetate | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of SH3GLB1 mRNA | CTD | PMID:26272509 | piroxicam | decreases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Piroxicam results in decreased expression of SH3GLB1 mRNA | CTD | PMID:21858171 | rac-lactic acid | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of SH3GLB1 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | EXP | | 6480464 | [resveratrol co-treated with Streptozocin] results in increased expression of SH3GLB1 mRNA | CTD | PMID:25905778 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SH3GLB1 mRNA | CTD | PMID:28374803 | silver atom | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Silver results in decreased expression of SH3GLB1 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | Silver results in decreased expression of SH3GLB1 mRNA | CTD | PMID:27131904 | sodium arsenate | increases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of SH3GLB1 mRNA | CTD | PMID:21795629 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of SH3GLB1 mRNA | CTD | PMID:19281266 | streptozocin | multiple interactions | EXP | | 6480464 | [resveratrol co-treated with Streptozocin] results in increased expression of SH3GLB1 mRNA | CTD | PMID:25905778 | succimer | multiple interactions | ISO | Sh3glb1 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SH3GLB1 mRNA | CTD | PMID:21641980 | sunitinib | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SH3GLB1 mRNA | CTD | PMID:31533062 | tert-butyl hydroperoxide | decreases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of SH3GLB1 mRNA | CTD | PMID:15336504 | testosterone | multiple interactions | ISO | SH3GLB1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of SH3GLB1 mRNA | CTD | PMID:21592394 | testosterone | increases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Testosterone results in increased expression of SH3GLB1 mRNA | CTD | PMID:21592394 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of SH3GLB1 gene | CTD | PMID:27618143 | triclosan | decreases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of SH3GLB1 mRNA | CTD | PMID:34681664 | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of SH3GLB1 mRNA | CTD | PMID:30589522 | triptonide | increases expression | ISO | Sh3glb1 (Mus musculus) | 6480464 | triptonide results in increased expression of SH3GLB1 mRNA | CTD | PMID:33045310 | valproic acid | decreases expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SH3GLB1 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | SH3GLB1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SH3GLB1 mRNA | CTD | PMID:25979313 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of SH3GLB1 mRNA | CTD | PMID:29427782 | |