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Gene: Slc10a2 (solute carrier family 10 member 2) Rattus norvegicus
Symbol: Slc10a2
Name: solute carrier family 10 member 2
RGD ID: 3682
Description: Exhibits bile acid:sodium symporter activity. Involved in bile acid and bile salt transport. Localizes to apical plasma membrane; nucleus; and proteasome complex. Human ortholog(s) of this gene implicated in intestinal disease. Orthologous to human SLC10A2 (solute carrier family 10 member 2); PARTICIPATES IN bile acid transport pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17alpha-ethynylestradiol; 3,3',5-triiodo-L-thyronine.
Type: protein-coding
Also known as: apical sodium-dependent bile acid transporter; ASBT; IBAT; ileal Na(+)/bile acid cotransporter; ileal sodium-dependent bile acid transporter; ileal sodium/bile acid cotransporter; ISBAT; ISBT; Na(+)-dependent ileal bile acid transporter; sodium/taurocholate-cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family), member 2; solute carrier family 10 (sodium/bile acid cotransporter), member 2; solute carrier family 10, member 2
Homo sapiens (human) : SLC10A2 (solute carrier family 10 member 2)  HGNC  Alliance
Mus musculus (house mouse) : Slc10a2 (solute carrier family 10, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc10a2 (solute carrier family 10 member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC10A2 (solute carrier family 10 member 2)
Canis lupus familiaris (dog) : SLC10A2 (solute carrier family 10 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc10a2 (solute carrier family 10 member 2)
Sus scrofa (pig) : SLC10A2 (solute carrier family 10 member 2)
Chlorocebus sabaeus (African green monkey) : SLC10A2 (solute carrier family 10 member 2)
Heterocephalus glaber (naked mole-rat) : Slc10a2 (solute carrier family 10 member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01690,324,420 - 90,350,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1690,324,361 - 90,345,865 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01689,709,462 - 89,732,970 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41689,939,295 - 89,961,444 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11689,925,334 - 90,169,172 (+)NCBI
Celera1682,094,445 - 82,108,935 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc10a2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3682
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.