Gene: Ager (advanced glycosylation end product-specific receptor) Rattus norvegicus
Symbol: Ager
Name: advanced glycosylation end product-specific receptor
Description: ENCODES a protein that exhibits high mobility group box 1 binding; S100 protein binding; advanced glycation end-product binding (ortholog); INVOLVED IN brain development; calcium ion homeostasis; cellular response to drug; PARTICIPATES IN Ras mediated signaling pathway; receptor for advanced glycation end-products signaling pathway; ASSOCIATED WITH Acute Lung Injury; adult respiratory distress syndrome; Albuminuria; FOUND IN axon; basal plasma membrane; cell surface; INTERACTS WITH 3,4-dihydroxybenzaldehyde; acrolein; aldehydo-D-glucose
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: advanced glycosylation end product-specific receptor variant 2; advanced glycosylation end product-specific receptor variant 3; advanced glycosylation end product-specific receptor variant 4; advanced glycosylation end product-specific receptor variant 5; RAGE; receptor for advanced glycosylation end products
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0204,363,152 - 4,366,079 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,442,508 - 6,445,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,250,613 - 4,253,540 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,250,839 - 4,253,767 (-)NCBI
Celera203,879,126 - 3,882,053 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ager
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69258
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-01-08
Status: ACTIVE