Ager (advanced glycosylation end product-specific receptor) - Rat Genome Database

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Gene: Ager (advanced glycosylation end product-specific receptor) Rattus norvegicus
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Symbol: Ager
Name: advanced glycosylation end product-specific receptor
RGD ID: 69258
Description: Enables S100 protein binding activity and high mobility group box 1 binding activity. Involved in several processes, including positive regulation of apoptotic process; regulation of cell migration; and response to hexose. Located in several cellular components, including basal plasma membrane; cell surface; and neuronal cell body. Used to study several diseases, including diabetic retinopathy; impotence; renal fibrosis; thromboangiitis obliterans; and type 2 diabetes mellitus. Biomarker of several diseases, including bone disease (multiple); cardiovascular system disease (multiple); colorectal carcinoma; diabetic encephalopathy; and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); cardiovascular system disease (multiple); cystic fibrosis; kidney failure (multiple); and lupus nephritis. Orthologous to human AGER (advanced glycosylation end-product specific receptor); PARTICIPATES IN Ras mediated signaling pathway; receptor for advanced glycation end-products signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 3,4-dihydroxybenzaldehyde.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: advanced glycosylation end product-specific receptor variant 2; advanced glycosylation end product-specific receptor variant 3; advanced glycosylation end product-specific receptor variant 4; advanced glycosylation end product-specific receptor variant 5; RAGE; receptor for advanced glycosylation end products
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2204,148,150 - 4,151,361 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl204,147,890 - 4,151,078 (-)Ensembl
Rnor_6.0204,363,152 - 4,366,079 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,363,152 - 4,366,079 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,442,508 - 6,445,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,250,613 - 4,253,540 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,250,839 - 4,253,767 (-)NCBI
Celera203,879,126 - 3,882,053 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (IEP)
adult respiratory distress syndrome  (IEP)
Albuminuria  (IDA,ISO)
Alzheimer's disease  (IDA,IEP,ISO)
Aortic Calcification  (IEP)
aortic disease  (IEP)
aspergillosis  (ISO)
asthma  (IDA,IEP,ISO)
atherosclerosis  (IEP,ISO)
atrial fibrillation  (ISO)
bacterial pneumonia  (ISO)
Brain Injuries  (IEP,ISO)
brain ischemia  (IEP)
Breast Neoplasms  (ISO)
Cardiac Fibrosis  (IEP)
cardiovascular system disease  (IEP,ISO)
carotid artery disease  (IEP,ISO)
Carotid Artery Injuries  (IMP)
cerebral infarction  (ISO)
chorioamnionitis  (ISO)
Chronic Allograft Dysfunction  (IEP)
chronic kidney disease  (ISO)
chronic obstructive pulmonary disease  (ISO)
clear cell renal cell carcinoma  (ISO)
colorectal carcinoma  (IEP)
congestive heart failure  (ISO)
contact dermatitis  (ISO)
Cor pulmonale  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
cystic fibrosis  (ISO)
diabetes mellitus  (ISO)
diabetic angiopathy  (ISO)
Diabetic Cardiomyopathies  (IDA,IEP)
diabetic encephalopathy  (IEP)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (IDA,IEP,ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (IDA,IEP,ISO)
end stage renal disease  (ISO)
Epidermal Hyperplasia  (ISO)
Experimental Autoimmune Myocarditis  (IEP)
Experimental Diabetes Mellitus  (IDA,IEP,ISO)
Fibrosis  (IDA)
Gastrointestinal Diseases  (IDA,IEP)
glomerulosclerosis  (ISO)
Hyperalgesia  (IEP,IMP,ISO)
hyperglycemia  (ISO)
Hyperoxia  (IEP)
hypertension  (IEP,ISO)
Hypertrophy  (ISO)
impotence  (IDA)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
intracranial aneurysm  (IEP)
invasive aspergillosis  (ISO)
invasive ductal carcinoma  (ISO)
Kawasaki disease  (ISO)
kidney disease  (ISO)
Left Ventricular Hypertrophy  (ISO)
leishmaniasis  (ISO)
Lewy body dementia  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (IEP)
Lung Injury  (IEP)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (ISO)
melanoma  (ISO)
middle cerebral artery infarction  (IEP,ISO)
morbid obesity  (ISO)
multiple sclerosis  (ISO)
myocardial infarction  (IEP,ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (IEP)
Neointima  (ISO)
neovascular inflammatory vitreoretinopathy  (ISO)
Neuralgia  (ISO)
obesity  (ISO)
occupational asthma  (ISO)
optic nerve disease  (ISO)
osteoarthritis  (IEP,ISO)
osteoporosis  (IEP,ISO)
pancreas disease  (ISO)
pancreatic cancer  (ISO)
periodontitis  (IEP,ISO)
Peripheral Nerve Injuries  (ISO)
Peritoneal Fibrosis  (IDA)
polycystic kidney disease  (ISO)
proliferative diabetic retinopathy  (ISO)
prostate cancer  (ISO)
proteinuria  (ISO)
psoriasis  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (IEP,ISO)
pulmonary hypertension  (ISO)
renal fibrosis  (IDA,ISO)
rheumatoid arthritis  (ISO)
rosacea  (ISO)
schistosomiasis  (ISO)
schizophrenia  (ISO)
schizotypal personality disorder  (ISO)
Sepsis  (IMP)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (IEP)
Stroke  (IDA,ISO)
Subarachnoid Hemorrhage  (IEP)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (ISO)
Takayasu's arteritis  (ISO)
thromboangiitis obliterans  (IDA,IEP)
Tongue Neoplasms  (IDA)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (IEP,ISO)
tuberculosis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (IDA,IEP,ISO)
uremia  (IEP)
ureteral obstruction  (ISO)
Vascular Calcification  (ISO)
vascular skin disease  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Nornicotine  (ISO)
(-)-anisomycin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
3,4-dihydroxybenzaldehyde  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenylprop-2-enal  (EXP)
acrolein  (EXP,ISO)
acrylamide  (ISO)
acteoside  (ISO)
agomelatine  (EXP)
aldehydo-D-glucose  (EXP,ISO)
aldehydo-D-ribose  (ISO)
all-trans-retinol  (EXP)
allyl isothiocyanate  (ISO)
alpha-D-galactose  (EXP,ISO)
aminoguanidine  (ISO)
ammonium chloride  (EXP)
ampicillin  (ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
aristolochic acid  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
azathioprine  (ISO)
benazepril  (EXP)
benzo[a]pyrene  (ISO)
Bergenin  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP)
Bisphenol A diglycidyl ether  (EXP)
bleomycin A2  (EXP)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (EXP)
calcitriol  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carnosine  (ISO)
chlorohydrocarbon  (ISO)
cholesterol  (ISO)
cisplatin  (ISO)
curcumin  (EXP)
D-glucose  (EXP,ISO)
D-ribofuranose  (ISO)
dapagliflozin  (EXP)
dichlorine  (EXP)
diclofenac  (ISO)
dicloxacillin  (ISO)
dioxygen  (EXP)
disodium selenite  (EXP)
estriol  (ISO)
ethanol  (ISO)
Ethyl pyruvate  (ISO)
febuxostat  (EXP)
flutamide  (ISO)
fructose  (EXP)
fulvestrant  (ISO)
furan  (EXP)
galactose  (EXP,ISO)
gallic acid  (EXP)
genistein  (EXP)
gentamycin  (EXP)
geraniol  (EXP)
glucose  (EXP,ISO)
graphene oxide  (ISO)
hesperetin  (EXP)
Honokiol  (ISO)
hydrogen peroxide  (EXP)
leflunomide  (ISO)
linoleic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
losartan  (EXP)
luteolin  (ISO)
LY294002  (EXP)
lycopene  (ISO)
mangiferin  (EXP)
mebendazole  (ISO)
melatonin  (ISO)
mesalamine  (EXP)
metformin  (EXP)
methylglyoxal  (ISO)
methylmercury chloride  (EXP)
naphthalene  (ISO)
nitrofen  (EXP)
oleanolic acid  (ISO)
oxidopamine  (EXP)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (ISO)
pentetrazol  (EXP)
permethrin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pioglitazone  (EXP)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
procyanidin B2  (EXP)
procyanidin B3  (ISO)
propanal  (ISO)
protein kinase inhibitor  (EXP)
Pyridostigmine bromide  (ISO)
quercetin  (ISO)
reactive oxygen species  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
rutin  (ISO)
SB 203580  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
streptozocin  (EXP,ISO)
testosterone  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
vinclozolin  (EXP)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte activation  (ISO)
astrocyte development  (ISO)
brain development  (IEP)
calcium ion homeostasis  (IMP)
cellular response to amyloid-beta  (ISO)
cellular response to fatty acid  (IEP)
cellular response to glucose stimulus  (IEP)
cellular response to hydrogen peroxide  (IEP)
cellular response to organic cyclic compound  (IEP)
cellular response to xenobiotic stimulus  (IEP)
glucose mediated signaling pathway  (ISO)
glycoprotein metabolic process  (IEP)
induction of positive chemotaxis  (ISO)
inflammatory response  (ISO)
learning or memory  (ISO)
lung development  (IEP)
microglial cell activation  (ISO)
negative regulation of advanced glycation end-product receptor activity  (ISO)
negative regulation of blood circulation  (ISO)
negative regulation of cell adhesion  (IMP)
negative regulation of collagen biosynthetic process  (IMP)
negative regulation of connective tissue replacement involved in inflammatory response wound healing  (ISO)
negative regulation of endothelial cell migration  (IMP)
negative regulation of endothelial cell proliferation  (IMP)
negative regulation of interleukin-10 production  (ISO)
negative regulation of long-term synaptic depression  (ISO)
negative regulation of long-term synaptic potentiation  (ISO)
negative regulation of osteoblast proliferation  (IEP)
negative regulation of protein phosphorylation  (IMP)
neuron projection development  (IGI,IMP,ISO)
obsolete modulation of age-related behavioral decline  (ISO)
positive regulation of activated T cell proliferation  (ISO)
positive regulation of apoptotic process  (IMP)
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process  (ISO)
positive regulation of autophagy  (IMP)
positive regulation of cell migration  (IMP)
positive regulation of chemokine production  (ISO)
positive regulation of dendritic cell differentiation  (ISO)
positive regulation of endothelial cell apoptotic process  (IMP)
positive regulation of endothelin production  (ISO)
positive regulation of epithelial to mesenchymal transition  (IMP)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fibroblast migration  (IMP)
positive regulation of fibroblast proliferation  (IMP)
positive regulation of gene expression  (IMP)
positive regulation of heterotypic cell-cell adhesion  (ISO)
positive regulation of inflammatory response  (IMP)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of interleukin-12 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of JUN kinase activity  (ISO)
positive regulation of monocyte chemotactic protein-1 production  (ISO)
positive regulation of monocyte extravasation  (ISO)
positive regulation of neuron apoptotic process  (IMP)
positive regulation of neuron death  (IMP)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of NIK/NF-kappaB signaling  (ISO)
positive regulation of p38MAPK cascade  (ISO)
positive regulation of phagocytosis, engulfment  (IMP)
positive regulation of potassium ion transmembrane transporter activity  (IMP)
positive regulation of protein phosphorylation  (IMP,ISO)
positive regulation of reactive oxygen species metabolic process  (IMP)
positive regulation of smooth muscle cell migration  (IMP)
positive regulation of smooth muscle cell proliferation  (IMP)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of type B pancreatic cell apoptotic process  (IMP)
protein localization to membrane  (ISO)
receptor signaling pathway via JAK-STAT  (IMP)
regulation of CD4-positive, alpha-beta T cell activation  (ISO)
regulation of DNA binding  (ISO)
regulation of inflammatory response  (IBA,ISO)
regulation of long-term synaptic potentiation  (ISO)
regulation of p38MAPK cascade  (IBA,ISO)
regulation of spontaneous synaptic transmission  (ISO)
regulation of T cell mediated cytotoxicity  (ISO)
response to activity  (IEP)
response to amyloid-beta  (ISO)
response to fructose  (IEP)
response to genistein  (IEP)
response to hyperoxia  (IEP)
response to hypoxia  (ISO)
response to methylglyoxal  (IEP)
response to selenite ion  (IEP)
response to vitamin A  (IEP)
transcytosis  (ISO)
transdifferentiation  (IEP)
transport across blood-brain barrier  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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Genomics

Comparative Map Data
Ager
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2204,148,150 - 4,151,361 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl204,147,890 - 4,151,078 (-)Ensembl
Rnor_6.0204,363,152 - 4,366,079 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,363,152 - 4,366,079 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,442,508 - 6,445,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,250,613 - 4,253,540 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,250,839 - 4,253,767 (-)NCBI
Celera203,879,126 - 3,882,053 (+)NCBICelera
Cytogenetic Map20p12NCBI
AGER
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,180,969 - 32,184,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl632,180,968 - 32,184,322 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,148,746 - 32,152,030 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,256,724 - 32,260,001 (-)NCBINCBI36hg18NCBI36
Build 34632,256,723 - 32,260,001NCBI
Celera633,715,793 - 33,719,070 (-)NCBI
Cytogenetic Map6p21.32NCBI
HuRef631,902,943 - 31,906,297 (-)NCBIHuRef
CHM1_1632,151,229 - 32,154,583 (-)NCBICHM1_1
Ager
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,816,545 - 34,819,911 (+)NCBIGRCm39mm39
GRCm39 Ensembl1734,816,836 - 34,819,910 (+)Ensembl
GRCm381734,597,460 - 34,600,937 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,597,862 - 34,600,936 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,734,807 - 34,737,877 (+)NCBIGRCm37mm9NCBIm37
MGSCv361734,205,945 - 34,208,989 (+)NCBImm8
Celera1737,693,022 - 37,696,092 (+)NCBICelera
Cytogenetic Map17B1NCBI
Ager
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437645,897 - 648,479 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437645,482 - 648,607 (-)NCBIChiLan1.0ChiLan1.0
AGER
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1632,708,251 - 32,711,641 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,708,251 - 32,711,641 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0631,828,363 - 31,831,981 (-)NCBIMhudiblu_PPA_v0panPan3
AGER
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,574,251 - 1,577,410 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,574,251 - 1,577,129 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,707,946 - 1,710,824 (-)NCBI
ROS_Cfam_1.0121,712,483 - 1,715,623 (-)NCBI
ROS_Cfam_1.0 Ensembl121,712,483 - 1,715,351 (-)Ensembl
UMICH_Zoey_3.1121,575,515 - 1,578,386 (-)NCBI
UNSW_CanFamBas_1.0121,641,097 - 1,643,974 (-)NCBI
UU_Cfam_GSD_1.0121,707,421 - 1,710,298 (-)NCBI
Ager
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494636,139,331 - 36,142,908 (-)NCBI
SpeTri2.0NW_0049367271,418,342 - 1,422,005 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGER
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,218,116 - 24,228,756 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,218,116 - 24,221,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2728,038,957 - 28,042,327 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGER
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,847,343 - 39,851,288 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1739,847,759 - 39,851,127 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604432,080,456 - 32,084,078 (-)NCBIVero_WHO_p1.0
Ager
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475424,138,086 - 24,140,900 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH133750  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,147,793 - 4,147,984 (-)MAPPERmRatBN7.2
Rnor_6.0204,366,245 - 4,366,435NCBIRnor6.0
Rnor_5.0206,445,601 - 6,445,791UniSTSRnor5.0
RGSC_v3.4204,250,257 - 4,250,447UniSTSRGSC3.4
Celera203,882,219 - 3,882,409UniSTS
RH 3.4 Map2053.3UniSTS
Cytogenetic Map20p12UniSTS
PMC162222P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,149,485 - 4,150,413 (-)MAPPERmRatBN7.2
Rnor_6.0204,363,817 - 4,364,744NCBIRnor6.0
Rnor_5.0206,443,173 - 6,444,100UniSTSRnor5.0
RGSC_v3.4204,251,948 - 4,252,875UniSTSRGSC3.4
Celera203,879,791 - 3,880,718UniSTS
Cytogenetic Map20p12UniSTS
AI453961  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,148,217 - 4,148,512 (-)MAPPERmRatBN7.2
Rnor_6.0204,365,717 - 4,366,011NCBIRnor6.0
Rnor_5.0206,445,073 - 6,445,367UniSTSRnor5.0
RGSC_v3.4204,250,681 - 4,250,975UniSTSRGSC3.4
Celera203,881,691 - 3,881,985UniSTS
RH 3.4 Map2053.83UniSTS
Cytogenetic Map20p12UniSTS
AI176804  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,151,744 - 4,151,845 (-)MAPPERmRatBN7.2
Rnor_6.0204,362,385 - 4,362,485NCBIRnor6.0
Rnor_5.0206,441,741 - 6,441,841UniSTSRnor5.0
RGSC_v3.4204,254,207 - 4,254,307UniSTSRGSC3.4
Celera203,878,359 - 3,878,459UniSTS
RH 3.4 Map2052.92UniSTS
Cytogenetic Map20p12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
737973Pia21Pristane induced arthritis QTL 214.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2036216564606812Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:78
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000000508, ENSRNOT00000072848
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 7
Medium 4 2 2 1 2 38 14 22 4
Low 3 39 55 39 18 39 8 11 36 21 18 8
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC084697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX883044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR475487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU164726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L33413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000000508   ⟹   ENSRNOP00000000508
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,147,890 - 4,151,078 (-)Ensembl
Rnor_6.0 Ensembl204,363,152 - 4,366,079 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000072848   ⟹   ENSRNOP00000066649
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,149,443 - 4,151,078 (-)Ensembl
Rnor_6.0 Ensembl204,363,186 - 4,366,050 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077205   ⟹   ENSRNOP00000075474
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,149,161 - 4,151,078 (-)Ensembl
Rnor_6.0 Ensembl204,363,508 - 4,365,317 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077561   ⟹   ENSRNOP00000073680
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,363,186 - 4,366,050 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080289
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,365,587 - 4,366,078 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000084841   ⟹   ENSRNOP00000072071
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,147,890 - 4,151,078 (-)Ensembl
Rnor_6.0 Ensembl204,363,186 - 4,366,050 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085277
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,147,890 - 4,151,078 (-)Ensembl
Rnor_6.0 Ensembl204,363,186 - 4,366,050 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089721
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,363,186 - 4,366,050 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091105
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,363,351 - 4,364,019 (+)Ensembl
RefSeq Acc Id: NM_053336   ⟹   NP_445788
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2204,148,150 - 4,151,078 (-)NCBI
Rnor_6.0204,363,152 - 4,366,079 (+)NCBI
Rnor_5.0206,442,508 - 6,445,435 (+)NCBI
RGSC_v3.4204,250,613 - 4,253,540 (-)RGD
Celera203,879,126 - 3,882,053 (+)RGD
Sequence:
RefSeq Acc Id: XM_006256025   ⟹   XP_006256087
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2204,148,150 - 4,151,361 (-)NCBI
Rnor_6.0204,363,153 - 4,366,078 (+)NCBI
Rnor_5.0206,442,508 - 6,445,435 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_445788   ⟸   NM_053336
- Peptide Label: precursor
- UniProtKB: Q6MG86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256087   ⟸   XM_006256025
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K218 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075474   ⟸   ENSRNOT00000077205
RefSeq Acc Id: ENSRNOP00000072071   ⟸   ENSRNOT00000084841
RefSeq Acc Id: ENSRNOP00000066649   ⟸   ENSRNOT00000072848
RefSeq Acc Id: ENSRNOP00000000508   ⟸   ENSRNOT00000000508
RefSeq Acc Id: ENSRNOP00000073680   ⟸   ENSRNOT00000077561
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63495-F1-model_v2 AlphaFold Q63495 1-402 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701339
Promoter ID:EPDNEW_R11863
Type:multiple initiation site
Name:Ager_2
Description:advanced glycosylation end product-specific receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11864  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0204,363,173 - 4,363,233EPDNEW
RGD ID:13701347
Promoter ID:EPDNEW_R11864
Type:single initiation site
Name:Ager_1
Description:advanced glycosylation end product-specific receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11863  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0204,363,385 - 4,363,445EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69258 AgrOrtholog
BioCyc Gene G2FUF-4584 BioCyc
Ensembl Genes ENSRNOG00000000439 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000000508 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000066649 UniProtKB/TrEMBL
  ENSRNOP00000072071 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073680 UniProtKB/TrEMBL
  ENSRNOP00000075474 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000508 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000072848 UniProtKB/TrEMBL
  ENSRNOT00000077205 UniProtKB/TrEMBL
  ENSRNOT00000077561 UniProtKB/TrEMBL
  ENSRNOT00000084841 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7121345 IMAGE-MGC_LOAD
InterPro CD80_C2-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81722 UniProtKB/TrEMBL
MGC_CLONE MGC:105376 IMAGE-MGC_LOAD
NCBI Gene 81722 ENTREZGENE
Pfam C2-set_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ager PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC208219
UniProt A0A0G2K218 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K653_RAT UniProtKB/TrEMBL
  A0A0G2KAP4_RAT UniProtKB/TrEMBL
  F1ABR3_RAT UniProtKB/TrEMBL
  F1ABR4_RAT UniProtKB/TrEMBL
  F1ABR5_RAT UniProtKB/TrEMBL
  F1ABR6_RAT UniProtKB/TrEMBL
  M0RAU0_RAT UniProtKB/TrEMBL
  Q63495 ENTREZGENE
  Q6MG86 ENTREZGENE, UniProtKB/TrEMBL
  RAGE_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ager  advanced glycosylation end product-specific receptor       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_mapping is found within the rat major histocompatibility RT1 complex. 1300431
gene_process mediates interactions of advanced glycosylation end products (age), which accumulate in vascular tissue in aging and at an accelerated rate in diabetes 724707