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Gene: S100b (S100 calcium binding protein B) Rattus norvegicus
Symbol: S100b
Name: S100 calcium binding protein B
RGD ID: 3615
Description: Exhibits RAGE receptor binding activity; identical protein binding activity; and metal ion binding activity. Involved in several processes, including long-term synaptic potentiation; negative regulation of skeletal muscle cell differentiation; and positive regulation of myelination. Localizes to cytoplasm and extracellular space. Used to study demyelinating disease. Biomarker of several diseases, including bipolar disorder; borna disease; brain disease (multiple); mental depression; and sleep apnea. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-pilocarpine; (R)-lipoic acid; 1,2-dimethylhydrazine.
Type: protein-coding
Also known as: MGC93559; protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100P
Homo sapiens (human) : S100B (S100 calcium binding protein B)  HGNC  Alliance
Mus musculus (house mouse) : S100b (S100 protein, beta polypeptide, neural)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S100b (S100 calcium binding protein B)
Pan paniscus (bonobo/pygmy chimpanzee) : S100B (S100 calcium binding protein B)
Canis lupus familiaris (dog) : S100B (S100 calcium binding protein B)
Sus scrofa (pig) : S100B (S100 calcium binding protein B)
Chlorocebus sabaeus (African green monkey) : S100B (S100 calcium binding protein B)
Heterocephalus glaber (naked mole-rat) : S100b (S100 calcium binding protein B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02013,130,633 - 13,142,856 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,130,636 - 13,142,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02015,287,745 - 15,296,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42012,791,440 - 12,824,508 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12012,791,666 - 12,824,735 (-)NCBI
Celera2013,867,276 - 13,875,895 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on S100b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3615
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.