S100B (S100 calcium binding protein B) - Rat Genome Database

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Gene: S100B (S100 calcium binding protein B) Pan paniscus
Analyze
Symbol: S100B
Name: S100 calcium binding protein B
RGD ID: 11730501
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN adaptive thermogenesis (ortholog); astrocyte differentiation (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); Alzheimer's disease (ortholog); Animal Disease Models (ortholog); FOUND IN cytosol (ortholog); extracellular region (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22242,780,225 - 42,786,453 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12137,589,861 - 37,596,083 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02133,063,845 - 33,070,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12146,197,750 - 46,203,953 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2146,197,750 - 46,203,953 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
Alzheimer's disease  (ISO)
Animal Disease Models  (ISO)
aspergillosis  (ISO)
asphyxia neonatorum  (ISO)
Attention Deficit and Disruptive Behavior Disorders  (ISO)
autistic disorder  (ISO)
Axenfeld-Rieger syndrome type 3  (ISO)
bacterial meningitis  (ISO)
bipolar disorder  (ISO)
borna disease  (ISO)
brain disease  (ISO)
brain edema  (ISO)
Brain Hypoxia-Ischemia  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Brain Neoplasms  (ISO)
Cerebral Hemorrhage  (ISO)
Creutzfeldt-Jakob disease  (ISO)
demyelinating disease  (ISO)
Dental Pulp Exposure  (ISO)
depressive disorder  (ISO)
Diffuse Brain Injuries  (ISO)
dilated cardiomyopathy  (ISO)
Down syndrome  (ISO)
epilepsy  (ISO)
Experimental Diabetes Mellitus  (ISO)
Femoral Fractures  (ISO)
Hematoma  (ISO)
hepatic encephalopathy  (ISO)
hypertension  (ISO)
Hypotension  (ISO)
Inflammation  (ISO)
intracranial vasospasm  (ISO)
intrahepatic cholangiocarcinoma  (ISO)
invasive aspergillosis  (ISO)
Machado-Joseph disease  (ISO)
malignant mesothelioma  (ISO)
Mercury Poisoning, Nervous System  (ISO)
middle cerebral artery infarction  (ISO)
migraine without aura  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
nephrotoxicity  (ISO)
neuromyelitis optica  (ISO)
Parkinson's disease  (ISO)
relapsing-remitting multiple sclerosis  (ISO)
Reperfusion Injury  (ISO)
schizophrenia  (ISO)
Sepsis  (ISO)
sleep apnea  (ISO)
Spinal Fractures  (ISO)
Sporadic Creutzfeldt-Jakob Disease  (ISO)
Stroke  (ISO)
urinary bladder cancer  (ISO)
visual epilepsy  (ISO)
West Nile fever  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
S100B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22242,780,225 - 42,786,453 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12137,589,861 - 37,596,083 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02133,063,845 - 33,070,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12146,197,750 - 46,203,953 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2146,197,750 - 46,203,953 (-)Ensemblpanpan1.1panPan2
S100B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382146,598,604 - 46,605,082 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2146,598,604 - 46,605,208 (-)EnsemblGRCh38hg38GRCh38
GRCh372148,018,517 - 48,024,995 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362146,842,959 - 46,849,463 (-)NCBINCBI36Build 36hg18NCBI36
Build 342146,842,958 - 46,849,424NCBI
Celera2133,131,698 - 33,138,202 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2133,398,429 - 33,404,960 (-)NCBIHuRef
CHM1_12147,579,370 - 47,585,892 (-)NCBICHM1_1
T2T-CHM13v2.02144,984,829 - 44,991,348 (-)NCBIT2T-CHM13v2.0
S100b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391076,089,670 - 76,097,153 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1076,089,687 - 76,096,993 (+)EnsemblGRCm39 Ensembl
GRCm381076,253,836 - 76,261,319 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1076,253,853 - 76,261,159 (+)EnsemblGRCm38mm10GRCm38
MGSCv371075,716,581 - 75,724,064 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361075,697,569 - 75,703,813 (+)NCBIMGSCv36mm8
Celera1077,297,763 - 77,305,246 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.76NCBI
S100b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,372,345 - 12,381,159 (-)NCBIGRCr8
mRatBN7.22012,372,866 - 12,381,619 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,372,881 - 12,394,743 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2013,071,830 - 13,080,530 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,432,755 - 12,441,455 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02012,904,538 - 12,913,238 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02013,130,633 - 13,142,856 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,130,636 - 13,142,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02015,287,745 - 15,296,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42012,791,440 - 12,824,508 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12012,791,666 - 12,824,735 (-)NCBI
Celera2013,867,276 - 13,875,895 (-)NCBICelera
Cytogenetic Map20p12NCBI
S100b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540742,972,584 - 42,980,510 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540742,972,584 - 42,980,510 (-)NCBIChiLan1.0ChiLan1.0
S100B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13139,783,990 - 39,788,289 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3139,784,506 - 39,788,183 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3139,014,186 - 39,018,506 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03139,427,666 - 39,431,986 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13139,288,949 - 39,293,268 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03139,249,760 - 39,254,080 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03139,768,041 - 39,772,361 (-)NCBIUU_Cfam_GSD_1.0
S100B
(Sus scrofa - pig)		 No map positions available.
S100B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1290,188,820 - 90,194,986 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl290,188,639 - 90,195,023 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605418,611,924 - 18,618,244 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
S100b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474531,645,927 - 31,652,832 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474531,645,927 - 31,652,846 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000038047   ⟹   ENSPPAP00000015356
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2146,197,750 - 46,203,953 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000038055   ⟹   ENSPPAP00000015365
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2146,198,250 - 46,201,212 (-)Ensembl
RefSeq Acc Id: XM_008977472   ⟹   XP_008975720
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22242,780,225 - 42,786,453 (-)NCBI
NHGRI_mPanPan12137,589,861 - 37,596,083 (-)NCBI
Mhudiblu_PPA_v02133,063,845 - 33,070,073 (-)NCBI
PanPan1.12146,197,750 - 46,203,953 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034947914   ⟹   XP_034803805
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22242,780,225 - 42,786,388 (-)NCBI
NHGRI_mPanPan12137,589,861 - 37,596,016 (-)NCBI
Mhudiblu_PPA_v02133,063,845 - 33,070,007 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008975720 (Get FASTA)   NCBI Sequence Viewer  
  XP_034803805 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000015356
  ENSPPAP00000015356.1
  ENSPPAP00000015365.1
RefSeq Acc Id: XP_008975720   ⟸   XM_008977472
- UniProtKB: A0A2R9ADJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034803805   ⟸   XM_034947914
- UniProtKB: A0A2R9ADJ6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000015365   ⟸   ENSPPAT00000038055
Ensembl Acc Id: ENSPPAP00000015356   ⟸   ENSPPAT00000038047
Protein Domains
EF-hand   S100/CaBP-9k-type calcium binding subdomain


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030816 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038047.1 UniProtKB/TrEMBL
  ENSPPAT00000038055.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  S100-B UniProtKB/TrEMBL
  S100/CaBP-9k_CS UniProtKB/TrEMBL
  S100_Ca-bd_sub UniProtKB/TrEMBL
KEGG Report pps:100972982 UniProtKB/TrEMBL
NCBI Gene S100B ENTREZGENE
PANTHER PTHR11639:SF134 UniProtKB/TrEMBL
  S100 CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
Pfam EF-hand_1 UniProtKB/TrEMBL
  S_100 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  S100_CABP UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  S_100 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A2R9ADH5_PANPA UniProtKB/TrEMBL
  A0A2R9ADJ6 ENTREZGENE, UniProtKB/TrEMBL